A new shrinkage estimator for dispersion improves differential expression detection in RNA-seq data

Biostatistics

Volumn 14, Issue 2, 2013, Pages 232-243

  Wu, Hao ^a   Wang, Chi ^b   Wu, Zhijin ^c  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Differential expression; Empirical Bayes; RNA sequencing; Shrinkage estimator

Indexed keywords

ARTICLE; BAYES THEOREM; BINOMIAL DISTRIBUTION; BIOSTATISTICS; GENE EXPRESSION PROFILING; HUMAN; NUCLEIC ACID DATABASE; POISSON DISTRIBUTION; SEQUENCE ANALYSIS; STATISTICAL MODEL; STATISTICS;

BAYES THEOREM; BINOMIAL DISTRIBUTION; BIOSTATISTICS; DATABASES, NUCLEIC ACID; GENE EXPRESSION PROFILING; HUMANS; MODELS, STATISTICAL; POISSON DISTRIBUTION; SEQUENCE ANALYSIS, RNA;

EID: 84874912212     PISSN: 14654644     EISSN: 14684357     Source Type: Journal    
DOI: 10.1093/biostatistics/kxs033     Document Type: Article

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