Ammonia in breath and emitted from skin

Journal of Breath Research

Volumn 7, Issue 1, 2013, Pages

  Schmidt, F M ^a,d   Vaittinen, O ^a   Metsala M ^a   Lehto, M ^b,c   Forsblom, C ^b,c   Groop, P H ^b,c   Halonen, L ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; MOUTHWASH; CREATININE; ION; QUATERNARY AMMONIUM DERIVATIVE; UREA;

ADULT; AMMONIA BLOOD LEVEL; ARTICLE; BREATHING; CONCENTRATION (PARAMETERS); FEMALE; HUMAN; HUMAN EXPERIMENT; HYDROLYSIS; MALE; NORMAL HUMAN; PH; PRIORITY JOURNAL; SKIN; BLOOD; BREATH ANALYSIS; CHEMISTRY; COMPARATIVE STUDY; EXHALATION; METABOLISM; MIDDLE AGED; MOUTH; NOSE; SALIVA; SPECTROSCOPY;

ADULT; AMMONIA; BREATH TESTS; CREATININE; EXHALATION; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; IONS; MALE; MIDDLE AGED; MOUTH; NOSE; QUATERNARY AMMONIUM COMPOUNDS; SALIVA; SKIN; SPECTRUM ANALYSIS; UREA;

EID: 84874911994     PISSN: 17527155     EISSN: 17527163     Source Type: Journal    
DOI: 10.1088/1752-7155/7/1/017109     Document Type: Article

References (66)

1. Wilkinson D J, Smeeton N J and Watt P W 2010 Ammonia metabolism, the brain and fatigue; revisiting the link Prog. Neurobiol. 91 200-19
2. Kearney D J, Hubbard T and Putnam D 2002 Breath ammonia measurement in Helicobacter pylori infection Dig. Dis. Sci. 47 2523-30 (Pubitemid 35305462)
3. Toda K, Li J and Dasgupta P K 2006 Measurement of ammonia in human breath with a liquid-film conductivity sensor Anal. Chem. 78 7284-91 (Pubitemid 44607575)
4. Smallegange R C, Verhulst N O and Takken W 2011 Sweaty skin: an invitation to bite? Trends Parasitol. 27 143-8
5. Hibbard T and Killard A J 2011 Breath ammonia analysis: clinical application and measurement CRC Crit. Rev. Anal. Chem. 41 21-35
6. Kim K-H, Jahan S A and Kabir E 2012 A review of breath analysis for diagnosis of human health Trend. Anal. Chem. 33 1-8
7. Lovett A M, Reid N M, Buckley J A, French J B and Cameron D M 1979 Real-time analysis of breath using an atmospheric-pressure ionization mass-spectrometer Biomed. Mass Spectrom. 6 91-7 (Pubitemid 9147100)
8. Davies S, Španěl P and Smith D 1997 Quantitative analysis of ammonia on the breath of patients in end-stage renal failure Kidney Int. 52 223-8 (Pubitemid 27321835)
9. 2 precursor ions Rapid Commun. Mass Spectrom. 12 763-6 (Pubitemid 28290279)
10. Smith D, Španěl P and Davies S 1999 Trace gases in breath of healthy volunteers when fasting and after a protein-calorie meal: a preliminary study J. Appl. Physiol. 87 1584-8
11. Diskin A M, Španěl P and Smith D 2003 Time variation of ammonia, acetone, isoprene and ethanol in breath: a quantitative SIFT-MS study over 30 days Physiol. Meas. 24 107-19 (Pubitemid 36330459)
12. Penault C, Španěl P and Smith D 2005 Detection of H-pylori infection by breath ammonia following urea ingestion Breath Analysis for Clinical Diagnosis and Therapeutic Monitoring ed A Amann and D Smith (Singapore: World Scientific) pp 393-9
13. Smith D, Wang T, Španěl P and Bloor R 2006 The increase of breath ammonia induced by niacin ingestion quantified by selected ion flow tube mass spectrometry Physiol. Meas. 27 437-44
14. Španěl P, Turner C, Wang T S, Bloor R and Smith D 2006 Generation of volatile compounds on mouth exposure to urea and sucrose: implications for exhaled breath analysis Physiol. Meas. 27 N7-17
15. Turner C, Španěl P and Smith D 2006 A longitudinal study of ammonia, acetone and propanol in the exhaled breath of 30 subjects using selected ion flow tube mass spectrometry, SIFT-MS Physiol. Meas. 27 321-37
16. Španěl P, Dryahina K and Smith D 2007 Acetone, ammonia and hydrogen cyanide in exhaled breath of several volunteers aged 4-83 years J. Breath Res. 1 011001
17. Španěl P, Dryahina K and Smith D 2007 The concentration distributions of some metabolites in the exhaled breath of young adults J. Breath Res. 1 026001
18. Turner C, Parekh B, Walton C, Španěl P, Smith D and Evans M 2008 An exploratory comparative study of volatile compounds in exhaled breath and emitted by skin using selected ion flow tube mass spectrometry Rapid Commun. Mass Spectrom. 22 526-32 (Pubitemid 351300587)
19. Wang T S, Pysanenko A, Dryahina K, Španěl P and Smith D 2008 Analysis of breath, exhaled via the mouth and nose, and the air in the oral cavity J. Breath Res. 2 037013
20. Smith D, Wang T, Pysanenko A and Španěl P 2008 A selected ion flow tube mass spectrometry study of ammonia in mouth- and nose-exhaled breath and in the oral cavity Rapid Commun. Mass Spectrom. 22 783-9 (Pubitemid 351442551)
21. Enderby B, Lenney W, Brady M, Emmett C, Španěl P and Smith D 2009 Concentrations of some metabolites in the breath of healthy children aged 7-18 years measured using selected ion flow tube mass spectrometry (SIFT-MS) J. Breath Res. 3 036001
22. Boshier P R, Cushnir J R, Priest O H, Marczin N and Hanna G B 2010 Variation in the levels of volatile trace gases within three hospital environments: implications for clinical breath testing J. Breath Res. 4 031001
23. Endre Z H, Pickering J W, Storer M K, Hu W P, Moorhead K T, Allardyce R, McGregor D O and Scotter J M 2011 Breath ammonia and trimethylamine allow real-time monitoring of haemodialysis efficacy Physiol. Meas. 32 115-30
24. Neri G, Lacquaniti A, Rizzo G, Donato N, Latino M and Buemi M 2012 Real-time monitoring of breath ammonia during haemodialysis: use of ion mobility spectrometry (IMS) and cavity ring-down spectroscopy (CRDS) techniques Nephrol. Dial. Transplant. 27 2945-52
25. Moskalenko K L, Nadezhdinskii A I and Adamovskaya I A 1996 Human breath trace gas content study by tunable diode laser spectroscopy technique Infrared Phys. Technol. 37 181-92 (Pubitemid 126337923)
26. Narasimhan L R, Goodman W and Patel C K 2001 Correlation of breath ammonia with blood urea nitrogen and creatinine during hemodialysis Proc. Natl Acad. Sci. USA 98 4617-21 (Pubitemid 32295025)
27. DuBois S, Eng S, Bhattacharya R, Rulyak S, Hubbard T, Putnam D and Kearney D J 2005 Breath ammonia testing for diagnosis of hepatic encephalopathy Dig. Dis. Sci. 50 1780-4 (Pubitemid 41413890)
28. Manne J, Sukhorukov O, Jäger W and Tulip J 2006 Pulsed quantum cascade laser-based cavity ring-down spectroscopy for ammonia detection in breath Appl. Opt. 45 9230-7 (Pubitemid 46224850)
29. Stamyr K, Vaittinen O, Jaakola J, Guss J, Metsälä M, Johanson G and Halonen L 2009 Background levels of hydrogen cyanide in human breath measured by infrared cavity ring down spectroscopy Biomarkers 14 285-91
30. Hibbard T and Killard A J 2011 Breath ammonia levels in a normal human population study as determined by photoacoustic laser spectroscopy J. Breath Res. 5 037101
31. Lewicki R, Kosterev A A, Thomazy D M, Risby T H, Solga S, Schwartz T B and Tittel F K 2011 Real time ammonia detection in exhaled human breath using a distributed feedback quantum cascade laser based sensor Proc. SPIE 7945 79450K
32. Popa C, Dutu D, Cernat R, Matei C, Bratu A, Banita S and Dumitras D 2011 Ethylene and ammonia traces measurements from the patients' breath with renal failure via LPAS method Appl. Phys. B 105 669-74
33. Wang J, Xie H, Liang L, Zhang W, Peng W and Yu Q 2012 Tunable fiber laser based photoacoustic spectrometer for breath ammonia analysis during hemodialysis Laser Phys. 22 327-30
34. Norwood D M, Wainman T, Lioy P J and Waldman J M 1992 Breath ammonia depletion and its relevance to acidic aerosol exposure studies Arch. Environ. Health 47 309-13
35. Wakabayashi H, Kuwabara Y, Murata H, Kobashi K and Watanabe A 1997 Measurement of the expiratory ammonia concentration and its clinical significance Metab. Brain Dis. 12 161-9 (Pubitemid 27264267)
36. Shimamoto C, Hirata I and Katsu K 2000 Breath and blood ammonia in liver cirrhosis Hepatogastroenterology 47 443-5 (Pubitemid 30216310)
37. Timmer B, Olthuis W and Berg A 2005 Ammonia sensors and their applications: a review Sensors Actuators B 107 666-77
38. 3 sensor Biomed. Mater. Eng. 18 99-106 (Pubitemid 352040124)
39. Gouma P, Kalyanasundaram K, Yun X, Stanacevic M and Wang L S 2010 Nanosensor and breath analyzer for ammonia detection in exhaled human breath IEEE Sensors J. 10 49-53
40. Adrover R, Cocozzella D, Ridruejo E, Garca A, Rome J and Podestá J 2012 Breath-ammonia testing of healthy subjects and patients with cirrhosis Dig. Dis. Sci. 57 189-95
41. Nose K, Mizuno T, Yamane N, Kondo T, Ohtani H, Araki S and Tsuda T 2005 Identification of ammonia in gas emanated from human skin and its correlation with that in blood Anal. Sci. 21 1471-4 (Pubitemid 41797870)
42. Imran M, Shah Y, Nundlall S, Roberts N B and Howse M 2012 Is blood ammonia influenced by kidney function? A prospective study Clin. Biochem. 45 363-5
43. Anderson J C, Babb A L and Hlastala M P 2003 Modeling soluble gas exchange in the airways and alveoli Ann. Biomed. Eng. 31 1402-22
44. King J, Unterkofler K, Teschl G, Teschl S, Koc H, Hinterhuber H and Amann A 2011 A mathematical model for breath gas analysis of volatile organic compounds with special emphasis on acetone J. Math. Biol. 63 959-99
45. Berden G and Engeln R (ed) 2009 Cavity Ring-Down Spectroscopy: Techniques and Applications (New York: Wiley) 322 pp
46. Schmidt F M, Vaittinen O, Metsälä M, Kraus P and Halonen L 2010 Direct detection of acetylene in air by continuous wave cavity ring-down spectroscopy Appl. Phys. B 101 671-82
47. 4 in human plasma, isotonic salt solutions and water at 37 degrees C Clin. Chim. Acta 273 43-58 (Pubitemid 29044054)
48. Schmohl A, Miklos A and Hess P 2001 Effects of adsorption-desorption processes on the response time and accuracy of photoacoustic detection of ammonia Appl. Opt. 40 2571-8
49. O'Hara M E, O'Hehir S, Green S and Mayhew C A 2008 Development of a protocol to measure volatile organic compounds in human breath: a comparison of rebreathing and on-line single exhalations using proton transfer reaction mass spectrometry Physiol. Meas. 29 309-30 (Pubitemid 351423042)
50. Schmidt F M, Metsälä M, Vaittinen O and Halonen L 2011 Background levels and diurnal variations of hydrogen cyanide in breath and emitted from skin J. Breath Res. 5 046004
51. Barsotti R J 2001 Measurement of ammonia in blood J. Pediatr. 138 S11-20 (Pubitemid 32099499)
52. Huizenga J R, Vissink A, Kuipers E J and Gips C H 1999 Helicobacter pylori and ammonia concentrations of whole, parotid and submandibular/sublingual saliva Clin. Oral Invest. 3 84-7
53. Sato K 1977 The physiology, pharmacology, and biochemistry of the eccrine sweat gland Rev. Phys., Biochem. Pharmacol. 79 51-131
54. Brusilow S W and Gordes E H 1968 Ammonia secretion in sweat Am. J. Physiol. 214 513-7
55. Vaittinen O, Schmidt F M, Metsälä M and Halonen L 2012 Exhaled breath biomonitoring using laser spectroscopy Curr. Anal. Chem. at press
56. Meulenbelt J 2012 Ammonia Medicine 40 94-5
57. Cardoso E M L, Arregger A L, Tumilasci O R, Elbert A and Contreras L N 2009 Assessment of salivary urea as a less invasive alternative to serum determinations Scand. J. Clin. Lab. Invest. 69 330-4
58. Baxmann A C, Ahmed M S, Marques N C, Menon V B, Pereira A B, Kirsztajn G M and Heilberg I P 2008 Influence of muscle mass and physical activity on serum and urinary creatinine and serum cystatin C Clin. J. Am. Soc. Nephrol. 3 348-54
59. Kho H-S, Lee S-W, Chung S-C and Kim Y-K 1999 Oral manifestations and salivary flow rate, pH, and buffer capacity in patients with end-stage renal disease undergoing hemodialysis Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 88 316-9
60. Bots C P et al 2007 Acute effects of hemodialysis on salivary flow rate and composition Clin. Nephrol. 67 25-31 (Pubitemid 46321740)
61. Tomás I, Marinho J S, Limeres J, Santos M J, Araújo L and Diz P 2008 Changes in salivary composition in patients with renal failure Arch. Oral Biol. 53 528-32
62. Bayraktar G, Kurtulus I, Kazancioglu R, Bayramgurler I, Cintan S, Bural C, Bozfakioglu S, Issever H and Yildiz A 2009 Oral health and inflammation in patients with end-stage renal failure Perit. Dial. Int. 29 472-9
63. Mydlik M and Derzsiová K 2008 Oxalic acid as a uremic toxin J. Renal Nutrition 18 33-9 (Pubitemid 350251825)
64. Raimann J G, Kirisits W, Gebetsroither E, Carter M, Callegari J, Rosales L, Levin N W and Kotanko P 2011 Saliva urea dipstick test: application in chronic kidney disease Clin. Nephrol. 76 23-8
65. Emrich H M and Oelert H 1966 pH-Wert und Gesamtammoniak im menschlichen Schweiss Pflugers Arch. Ges. Phys. 290 311-4
66. Czarnowski D, Górski J, Jóźwiuk J and Boroń-Kaczmarska A 1992 Plasma ammonia is the principal source of ammonia in sweat Eur. J. Appl. Physiol. Occup. Physiol. 65 135-7