Implementing genome-informed personalized medicine in the U.S. Air Force Medical Service via the Patient-Centered Precision Care Research (PC2-Z) Program

Johns Hopkins APL Technical Digest (Applied Physics Laboratory)

Volumn 31, Issue 4, 2013, Pages 333-344

  Bradburne, Christopher E ^a,b   Carruth, Lucy M ^a,b   Lin, Jeffrey S ^b,c   Sivakumar, Ashok ^c,d   Benson, John H ^c,e   Vogel, Ruth A ^b,d  

^a Asymmetric Operations Department   (United States)

^b PC2 Z Program   (United States)

^c Research and Exploratory Development Department (REDD)   (United States)

^d CUS ^*  (United States)

^e Transportation Security Administration Infrastructure Modernization   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL CARE; CLINICAL KNOWLEDGE; FOCUS AREAS; GENOMIC INFORMATION; MEDICAL SERVICES; PERSONALIZED HEALTHCARE; PERSONALIZED MEDICINES; U.S. AIR FORCE;

BIOINFORMATICS; GENES; HEALTH CARE; MILITARY AVIATION; RESEARCH;

PROGRAM TRANSLATORS;

EID: 84874895970     PISSN: 02705214     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Varmus, H., "Ten Years On - The Human Genome and Medicine," N. Engl. J. Med. 362(21), 2028-2029 (2010).
2. Evans, J. P., Meslin, E. M., Marteau, T. M., and Caulfield, T., "Deflating the Genomic Bubble," Science 331(6019), 861-862 (2011).
3. Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., et al., "The Sequence of the Human Genome," Science 291(5507), 1304-1351 (2001).
4. International Hap Map Consortium, "The International HapMap Project," Nature 426(6968), 789-796 (2003).
5. Manolio, T. A., "Genomewide Association Studies and Assessment of the Risk of Disease," N. Engl. J. Med. 363(2), 166-176 (2010).
6. Imai, K., Kricka, L. J., and Fortina, P., "Concordance Study of 3 Direct-to-Consumer Genetic-Testing Services," Clin. Chem. 57(3), 518-521 (2011).
7. Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., et al., "Finding the Missing Heritability of Complex Diseases," Nature 461(7265), 747-753 (2009).
8. The 1000 Genomes Project Consortium, "A Map of Human Genome Variation from Population Scale Sequencing," Nature 467 (7319), 1061-1073 (2010).
9. Mardis, E. R., "The $1,000 Genome, the $100,000 Analysis?" Genomic Med. 2(11), 84 (2010).
10. Davies, K., The $1,000 Genome: The Revolution in DNA Sequencing and the New Era of Personalized Medicine, New York Free Press, New York (2010).
11. Hindorff, L. A., MacArthur, J. (European Bioinformatics Institute), Morales, J. (European Bioinformatics Institute), Junkins, H. A., Hall, P. N., Klemm, A. K., and Manolio, T. A., "A Catalog of Published Genome-Wide Association Studies," http://www.genome.gov/gwastudies, accessed March 2013.
12. Kronenthal, C. J., Delaney, S. K., and Christman, M. F., "Broadening Research Consent in the Era of Genome-Informed Medicine," Genet. Med. 14 (4), 432-436 (2012).
13. Kohane, I. S., Mandl, K. D., Taylor, P. L., Holm, I. A., Nigrin, D. J., and Kunkel, L. M., "Reestablishing the Researcher-Patient Compact," Science 316 (5826), 836-837 (2007).
14. Stack, C. B., Gharani, N., Gordon, E. S., Schmidlen, T., Christman, M. F., and Keller, M. A., "Genetic Risk Estimation in the Coriell Personalized Medicine Collaborative," Genet. Med. 13(2), 131-139 (2011).
15. Keller, M. A., Gordon, E. S., Stack, C. B., Gharani, N., Schmidlen, T. J., et al., "Coriell Personalized Medicine Collaborative: A Prospective Study of the Utility of Personalized Medicine," Per. Med. 7(3), 301-317 (2010).
16. Pollack, C. E., Gidengil, C., and Mehrotra, A., "The Growth of Retail Clinics and the Medical Home: Two Trends in Concert or in Conflict?" Health Affairs 29(5), 998-1003 (2010).
17. Wade, C. H., McBride, C. M., Kardia, S. L., and Brody, L. C., "Considerations for Designing a Prototype Genetic Test for Use in Translational Research," Public Health Genomics 13(3), 155-165 (2010).
18. Mazmanian, P. E., and Davis, D. A., "Continuing Medical Education and the Physician as a Learner: Guide to the Evidence," J. Am. Med. Assoc. 288(9), 1057-1060 (2002).
19. Sharp, R. R., Goldlust, M. E., and Eng, C., "Addressing Gaps in Physician Education Using Personal Genomic Testing," Genet. Med. 13(8), 750-751 (2011).
20. Williams, M. S., "The Public Health Genomics Translation Gap: What We Don't Have and Why It Matters," Public Health Genomics 15(3-4), 132-138 (2012).