Genistein Up-Regulates Tumor Suppressor MicroRNA-574-3p in Prostate Cancer

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Chiyomaru, Takeshi ^a   Yamamura, Soichiro ^a   Fukuhara, Shinichiro ^a   Hidaka, Hideo ^b   Majid, Shahana ^a   Saini, Sharanjot ^a   Arora, Sumit ^a   Deng, Guoren ^a   Shahryari, Varahram ^a   Chang, Inik ^a   Tanaka, Yuichiro ^a   Tabatabai, Z Laura ^c   Enokida, Hideki ^b   Seki, Naohiko ^d   Nakagawa, Masayuki ^b   Dahiya, Rajvir ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; GENISTEIN; JANUS KINASE; MICRORNA; MICRORNA 574 3P; PROTEIN BCL XL; STAT PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CANCER STAGING; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; GLEASON SCORE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROSTATE CANCER; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA BINDING; UPREGULATION; WNT SIGNALING PATHWAY;

3' UNTRANSLATED REGIONS; AGED; AGED, 80 AND OVER; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BASE PAIRING; BASE SEQUENCE; BINDING SITES; CELL MOVEMENT; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; GENISTEIN; HUMANS; MALE; MICE; MICRORNAS; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROSTATIC NEOPLASMS; RNA INTERFERENCE;

EID: 84874878684     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058929     Document Type: Article

References (55)

1. Siegel R, Naishadham D, Jemal A, (2012) Cancer statistics, 2012. CA Cancer J Clin 62: 10-29.
2. Mehlen P, Puisieux A, (2006) Metastasis: a question of life or death. Nat Rev Cancer 6: 449-458.
3. Attar RM, Takimoto CH, Gottardis MM, (2009) Castration-resistant prostate cancer: locking up the molecular escape routes. Clin Cancer Res 15: 3251-3255.
4. Nelson CJ, Lee JS, Gamboa MC, Roth AJ, (2008) Cognitive effects of hormone therapy in men with prostate cancer: a review. Cancer 113: 1097-1106.
5. Li Y, Sarkar FH, (2002) Inhibition of nuclear factor kappaB activation in PC3 cells by genistein is mediated via Akt signaling pathway. Clin Cancer Res 8: 2369-2377.
6. de Souza PL, Russell PJ, Kearsley JH, Howes LG, (2010) Clinical pharmacology of isoflavones and its relevance for potential prevention of prostate cancer. Nutr Rev 68: 542-555.
7. Pavese JM, Farmer RL, Bergan RC, (2010) Inhibition of cancer cell invasion and metastasis by genistein. Cancer Metastasis Rev 29: 465-482.
8. Li Y, Sarkar FH, (2002) Gene expression profiles of genistein-treated PC3 prostate cancer cells. J Nutr 132: 3623-3631.
9. Brodersen P, Voinnet O, (2009) Revisiting the principles of microRNA target recognition and mode of action. Nat Rev Mol Cell Biol 10: 141-148.
10. Lai EC, (2002) Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. Nat Genet 30: 363-364.
11. Friedman RC, Farh KK, Burge CB, Bartel DP, (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19: 92-105.
12. Ryan BM, Robles AI, Harris CC, (2010) Genetic variation in microRNA networks: The implications for cancer research. Nat Rev Cancer 10: 389-402.
13. Croce CM, (2009) Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet 10: 704-714.
14. Zhang B, Pan X, Cobb GP, Anderson TA, (2007) microRNAs as oncogenes and tumor suppressors. Dev Biol 302: 1-12.
15. Zaman MS, Shahryari V, Deng G, Thamminana S, Saini S, et al. (2012) Up-regulation of microRNA-21 correlates with lower kidney cancer survival. PLoS One 7: e31060.
16. Chen Y, Zaman MS, Deng G, Majid S, Saini S, et al. (2011) MicroRNAs 221/222 and genistein-mediated regulation of ARHI tumor suppressor gene in prostate cancer. Cancer Prev Res (Phila) 4: 76-86.
17. Chiyomaru T, Yamamura S, Zaman MS, Majid S, Deng G, et al. (2012) Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151. PLoS ONE 7: e43812.
18. Fuse M, Kojima S, Enokida H, Chiyomaru T, Yoshino H, et al. (2012) Tumor suppressive microRNAs (miR-222 and miR-31) regulate molecular pathways based on microRNA expression signature in prostate cancer. J Hum Genet [In press].
19. Tabas-Madrid D, Nogales-Cadenas R, Pascual-Montano A, (2012) GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics. Nucleic Acids Res40: W478-483.
20. Nogales-Cadenas R, Carmona-Saez P, Vazquez M, Vicente C, Yang X, et al. (2009) GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information. Nucleic Acids Res 37: W317-322.
21. Carmona-Saez P, Chagoyen M, Tirado F, Carazo JM, Pascual-Montano A, (2007) GENECODIS: a web-based tool for finding significant concurrent annotations in gene lists. Genome Biol 8: R3.
22. Khan N, Adhami VM, Mukhtar H, (2010) Apoptosis by dietary agents for prevention and treatment of prostate cancer. Endocr Relat Cancer 17: R39-52.
23. Huang X, Chen S, Xu L, Liu Y, Deb DK, et al. (2005) Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells. Cancer Res 65: 3470-3478.
24. Xu L, Bergan RC, (2006) Genistein inhibits matrix metalloproteinase type 2 activation and prostate cancer cell invasion by blocking the transforming growth factor beta-mediated activation of mitogen-activated protein kinase-activated protein kinase 2-27-kDa heat shock protein pathway. Mol Pharmacol 70: 869-877.
25. Li Y, Che M, Bhagat S, Ellis KL, Kucuk O, et al. (2004) Regulation of gene expression and inhibition of experimental prostate cancer bone metastasis by dietary genistein. Neoplasia 6: 354-363.
26. Majid S, Dar AA, Saini S, Chen Y, Shahryari V, et al. (2010) Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer. Cancer Res 70: 2809-2818.
27. Guo Y, Wang S, Hoot DR, Clinton SK, (2007) Suppression of VEGF-mediated autocrine and paracrine interactions between prostate cancer cells and vascular endothelial cells by soy isoflavones. J Nutr Biochem 18: 408-417.
28. Sang N, Stiehl DP, Bohensky J, Leshchinsky I, Srinivas V, et al. (2003) MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. J Biol Chem 278: 14013-14019.
29. Vader P, van der Meel R, Symons MH, Fens MH, Pieters E, et al. (2011) Examining the role of Rac1 in tumor angiogenesis and growth: a clinically relevant RNAi-mediated approach. Angiogenesis 14: 457-466.
30. Luedde T, (2010) MicroRNA-151 and its hosting gene FAK (focal adhesion kinase) regulate tumor cell migration and spreading of hepatocellular carcinoma. Hepatology 52: 1164-1166.
31. Bao B, Wang Z, Ali S, Kong D, Li Y, et al. (2011) Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. Cancer Lett 307: 26-36.
32. Slusarz A, Shenouda NS, Sakla MS, Drenkhahn SK, Narula AS, et al. (2010) Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer. Cancer Res 70: 3382-3390.
33. Wang H, Li Q, Chen H, (2012) Genistein Affects Histone Modifications on Dickkopf-Related Protein 1 (DKK1) Gene in SW480 Human Colon Cancer Cell Line. PLoS One 7: e40955.
34. Zhang Y, Chen H, (2011) Genistein attenuates WNT signaling by up-regulating sFRP2 in a human colon cancer cell line. Exp Biol Med (Maywood) 236: 714-722.
35. Kim YS, Farrar W, Colburn NH, Milner JA, (2012) Cancer stem cells: potential target for bioactive food components. J Nutr Biochem 23: 691-698.
36. Traish AM, Morgentaler A, (2009) Epidermal growth factor receptor expression escapes androgen regulation in prostate cancer: a potential molecular switch for tumour growth. Br J Cancer 101: 1949-1956.
37. Di Lorenzo G, Tortora G, D'Armiento FP, De Rosa G, Staibano S, et al. (2002) Expression of epidermal growth factor receptor correlates with disease relapse and progression to androgen-independence in human prostate cancer. Clin Cancer Res 8: 3438-3444.
38. Shah RB, Ghosh D, Elder JT, (2006) Epidermal growth factor receptor (ErbB1) expression in prostate cancer progression: correlation with androgen independence. Prostate 66: 1437-1444.
39. Kefas B, Godlewski J, Comeau L, Li Y, Abounader R, et al. (2008) microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res 68: 3566-3572.
40. Giles KM, Barker A, Zhang PM, Epis MR, Leedman PJ, (2011) MicroRNA regulation of growth factor receptor signaling in human cancer cells. Methods Mol Biol 676: 147-163.
41. Chan LW, Wang FF, Cho WC, (2012) Genomic sequence analysis of EGFR regulation by microRNAs in lung cancer. Curr Top Med Chem 12: 920-926.
42. Tao J, Wu D, Xu B, Qian W, Li P, et al. (2012) microRNA-133 inhibits cell proliferation, migration and invasion in prostate cancer cells by targeting the epidermal growth factor receptor. Oncol Rep 27: 1967-1975.
43. Cho WC, Chow AS, Au JS, (2011) MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1. RNA Biol 8: 125-131.
44. Xu B, Wang N, Wang X, Tong N, Shao N, et al. (2012) MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer. Prostate 72: 1171-1178.
45. Li Y, Vandenboom TG 2nd, Wang Z, Kong D, Ali S, et al (2010) miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res 70: 1486-1495.
46. Katakowski M, Zheng X, Jiang F, Rogers T, Szalad A, et al. (2010) MiR-146b-5p suppresses EGFR expression and reduces in vitro migration and invasion of glioma. Cancer Invest 28: 1024-1030.
47. Yamaguchi G, Takanashi M, Tanaka M, Fujita K, Ohira T, et al. (2012) Isolation of miRNAs that target EGFR mRNA in human lung cancer. Biochem Biophys Res Commun 420: 411-416.
48. Green DR, Reed JC, (1998) Mitochondria and apoptosis. Science 281: 1309-1312.
49. Li X, Marani M, Mannucci R, Kinsey B, Andriani F, et al. (2001) Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells. Cancer Res 61: 1699-1706.
50. Kumi-Diaka J, Sanderson NA, Hall A, (2000) The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP. Biol Cell 92: 595-604.
51. Tatarano S, Chiyomaru T, Kawakami K, Enokida H, Yoshino H, et al. (2011) miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. Int J Oncol 39: 1099-1107.
52. Tatarano S, Chiyomaru T, Kawakami K, Enokida H, Yoshino H, et al. (2012) Novel oncogenic function of mesoderm development candidate 1 and its regulation by MiR-574-3p in bladder cancer cell lines. Int J Oncol 40: 951-959.
53. Saramäki OR, Porkka KP, Vessella RL, Visakorpi T, (2006) Genetic aberrations in prostate cancer by microarray analysis. Int J Cancer 119: 1322-1329.
54. Su Y, Ni Z, Wang G, Cui J, Wei C, et al. (2012) Aberrant expression of microRNAs in gastric cancer and biological significance of miR-574-3p. Int Immunopharmacol 13: 468-475.
55. Chiyomaru T, Enokida H, Tatarano S, Kawahara K, Uchida Y, et al. (2010) miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer. Br J Cancer 102: 883-891.