A myristoylated alanine-rich c kinase substrate-related peptide suppresses cytokine mrna and protein expression in lps-activated canine neutrophils

American Journal of Respiratory Cell and Molecular Biology

Volumn 48, Issue 3, 2013, Pages 314-321

  Li, Jingjing ^a   D'Annibale Tolhurst, Melissa A ^a   Adler, Kenneth B ^a   Fang, Shijing ^a   Yin, Qui ^a   Birkenheuer, Adam J ^a   Levy, Michael G ^a   Jones, Samuel L ^a   Sung, Eui Jae ^a   Hawkins, Eleanor C ^a   Yoder, Jeffrey A ^a   Nordone, Shila K ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Cytokine; Inflammation; MARCKS; Neutrophil

Indexed keywords

CXCL1 CHEMOKINE; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MARCKS PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; DOG; EPITHELIUM CELL; HUMAN; IMMUNOCOMPETENT CELL; INFLAMMATORY DISEASE; MOUSE; NEUTROPHIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEPSIS;

ANIMALS; DOGS; HUMANS; INTERLEUKIN-8; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; NEUTROPHILS; PEPTIDES; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84874841020     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0278OC     Document Type: Article

References (34)

1. Fujishima S, Aikawa N. Neutrophil-mediated tissue injury and its modulation. Intensive Care Med 1995;21:277-285.
2. Arbuzova A, Schmitz AA, Vergeres G. Cross-talk unfolded: MARCKS proteins. Biochem J 2002;362:1-12.
3. Eckert RE, Neuder LE, Park J, Adler KB, Jones SL. Myristoylated alanine-rich C-kinase substrate (MARCKS) protein regulation of human neutrophil migration. Am J Respir Cell Mol Biol 2010;42:586-594.
4. Foster WM, Adler KB, Crews AL, Potts EN, Fischer BM, Voynow JA. MARCKS-related peptide modulates in vivo the secretion of airway MUC5AC. Am J Physiol Lung Cell Mol Physiol 2010;299:L345-L352.
5. Li J, Birkenheuer AJ, Marr HS, Levy MG, Yoder JA, Nordone SK. Expression and function of triggering receptor expressed on myeloid cells-1 (TREM-1) on canine neutrophils. Dev Comp Immunol 2011; 35:872-880.
6. Bastarache JA, Blackwell TS. Development of animal models for the acute respiratory distress syndrome. Dis Model Mech 2009;2:218-223.
7. Rittirsch D, Hoesel LM, Ward PA. The disconnect between animal models of sepsis and human sepsis. J Leukoc Biol 2007;81:137-143.
8. Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, et al. Clustal W and Clustal X version 2.0. Bioinformatics 2007;23:2947-2948.
9. Tamura K, Dudley J, Nei M, Kumar S. MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 2007; 24:1596-1599.
10. Nordone SK, Ignacio GA, Su L, Sempowski GD, Golenbock DT, Li L, Dean GA. Failure of TLR4-driven NF-kappa B activation to stimulate virus replication in models of HIV Type 1 activation. AIDS Res Hum Retroviruses 2007;23:1387-1395.
11. Pfaffl MW. A new mathematical model for relative quantification in realtime RT-PCR. Nucleic Acids Res 2001;29:e45.
12. Piedra PA, Poveda GA, Ramsey B, McCoy K, Hiatt PW. Incidence and prevalence of neutralizing antibodies to the common adenoviruses in children with cystic fibrosis: implication for gene therapy with adenovirus vectors. Pediatrics 1998;101:1013-1019.
13. Hu AY, Weng TC, Tseng YF, Chen YS, Wu CH, Hsiao S, Chou AH, Chao HJ, Gu A, Wu SC, et al. Microcarrier-based MDCK cell culture system for the production of influenza H5N1 vaccines. Vaccine 2008; 26:5736-5740.
14. Morral N, O'Neal W, Rice K, Leland M, Kaplan J, Piedra PA, Zhou H, Parks RJ, Velji R, Aguilar-Cordova E, et al. Administration of helperdependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons. Proc Natl Acad Sci USA 1999;96:12816-12821.
15. Suarez Butler MF, Langkamp-Henken B, Herrlinger-Garcia KA, Klash AE, Szczepanik ME, Nieves C Jr., Cottey RJ, Bender BS. Arginine supplementation enhances mitogen-induced splenocyte proliferation but does not affect in vivo indicators of antigen-specific immunity in mice. J Nutr 2005;135:1146-1150.
16. Temperton NJ, Hoschler K, Major D, Nicolson C, Manvell R, Hien VM, Ha Do Q, de Jong M, Zambon M, Takeuchi Y, et al. A sensitive retroviral pseudotype assay for influenza H5N1-neutralizing antibodies. Influenza Other Respir Viruses 2007;1:105-112.
17. Williams SB, Flanigan TP, Cu-Uvin S, Mayer K, Williams P, Ettore CA, Artenstein AW, Duerr A, VanCott TC. Human immunodeficiency obtained from women infected with HIV Type 1. Clin Infect Dis 2002; 35:611-617.
18. Thelen M, Rosen A, Nairn AC, Aderem A. Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate. Proc Natl Acad Sci USA 1990;87:5603-5607.
19. Vaaraniemi J, Palovuori R, Lehto VP, Eskelinen S. Translocation of MARCKS and reorganization of the cytoskeleton by PMA correlates with the ion selectivity, the confluence, and transformation state of kidney epithelial cell lines. J Cell Physiol 1999;181:83-95.
20. Singer M, Martin LD, Vargaftig BB, Park J, Gruber AD, Li Y, Adler KB. A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma. Nat Med 2004;10:193-196.
21. Takashi S, Park J, Fang S, Koyama S, Parikh I, Adler KB. A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate inhibits degranulation of human leukocytes in vitro. Am J Respir Cell Mol Biol 2006;34:647-652.
22. Attaur R, Harvey K, Siddiqui RA. Interleukin-8: an autocrine inflammatory mediator. Curr Pharm Des 1999;5:241-253.
23. Massion PP, Hebert CA, Leong S, Chan B, Inoue H, Grattan K, Sheppard D, Nadel JA. Staphylococcus aureus stimulates neutrophil recruitment by stimulating interleukin-8 production in dog trachea. Am J Physiol 1995;268:L85-L94.
24. Baggiolini M, Walz A, Kunkel SL. Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest 1989;84:1045-1049.
25. Schumacher C, Clark-Lewis I, Baggiolini M, Moser B. High-and lowaffinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophils. Proc Natl Acad Sci USA 1992;89:10542-10546.
26. Carr MW, Roth SJ, Luther E, Rose SS, Springer TA. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci USA 1994;91:3652-3656.
27. Xu LL, Warren MK, Rose WL, Gong W, Wang JM. Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro. J Leukoc Biol 1996;60:365-371.
28. Mancek-KeberM, BencinaM, Japelj B, Panter G, Andra J, Brandenburg K, Triantafilou M, Triantafilou K, Jerala R. Marcks as a negative regulator of lipopolysaccharide signaling. J Immunol 2012;188:3893-3902.
29. Damera G, Jester WF, Jiang M, Zhao H, Fogle HW, Mittelman M, Haczku A, Murphy E, Parikh I, Panettieri RA Jr. Inhibition of myristoylated alanine-rich C kinase substrate (MARCKS) protein inhibits ozone-induced airway neutrophilia and inflammation. Exp Lung Res 2010;36:75-84.
30. Newton K, Dixit VM. Signaling in innate immunity and inflammation. Cold Spring Harb Perspect Biol 2012;4.
31. Jiang C, Lin X. Regulation of NF-kappaB by the card proteins. Immunol Rev 2012;246:141-153.
32. Ivashkiv LB. Cross-regulation of signaling by ITAM-associated receptors. Nat Immunol 2009;10:340-347.
33. Li Y, Martin LD, Spizz G, Adler KB. MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro. J Biol Chem 2001;276:40982-40990.
34. Bhatia M, Zemans RL, Jeyaseelan S. Role of chemokines in the pathogenesis of acute lung injury. Am J Respir Cell Mol Biol 2012;46:566-572.