How could a drug used to treat alcoholism also be effective against glioblastoma?

Expert Review of Anticancer Therapy

Volumn 13, Issue 3, 2013, Pages 239-241

  Wang, Weiguang ^a   Darling, John L ^a  

^a UNIVERSITY OF WOLVERHAMPTON   (United Kingdom)

Author keywords

aldehyde dehydrogenase; copper; disulfiram; GBM stem like cells; NF kB; reactive oxygen species

Indexed keywords

ALDEHYDE DEHYDROGENASE; ANTINEOPLASTIC AGENT; DIETHYLDITHIOCARBAMIC ACID; DISULFIRAM; DITHIOCARBAMIC ACID DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; REACTIVE OXYGEN METABOLITE;

ALCOHOLISM; ANTINEOPLASTIC ACTIVITY; BLOOD BRAIN BARRIER; BREAST CANCER; CANCER RADIOTHERAPY; CANCER STEM CELL; CANCER SURGERY; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG RESISTANCE; DRUG SELECTIVITY; DRUG SENSITIZATION; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; GENE SILENCING; GLIOBLASTOMA; HUMAN; PROTEIN EXPRESSION; REVIEW; STRUCTURE ACTIVITY RELATION;

ALCOHOL DETERRENTS; ALCOHOLISM; ANTINEOPLASTIC AGENTS; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; DISULFIRAM; GLIOBLASTOMA; HUMANS;

EID: 84874830474     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/era.12.169     Document Type: Review

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