Evaluation of antiemetic effect of intravenous palonosetron versus intravenous ondansetron in laparoscopic cholecystectomy: A randomized controlled trial

Indian Journal of Pharmacology

Volumn 45, Issue 1, 2013, Pages 24-29

  Laha, Baisakhi ^a   Hazra, Avijit ^b   Mallick, S ^a  

^a Senior Adviser   (India)

^b INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Laparoscopic cholecystectomy; ondansetron; palonosetron; postoperative nausea and vomiting; randomized controlled trial

Indexed keywords

METOCLOPRAMIDE; ONDANSETRON; PALONOSETRON;

ADULT; ADVERSE OUTCOME; ANTIEMETIC ACTIVITY; ARTICLE; CHOLECYSTECTOMY; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; MALE; POSTOPERATIVE NAUSEA AND VOMITING; QT PROLONGATION; RANDOMIZED CONTROLLED TRIAL; RETCHING; SINGLE BLIND PROCEDURE; TREATMENT OUTCOME; TREATMENT RESPONSE;

LAPAROSCOPIC CHOLECYSTECTOMY; ONDANSETRON; PALONOSETRON; POSTOPERATIVE NAUSEA AND VOMITING; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, INTRAVENOUS; ADULT; AGED; ANTIEMETICS; CHOLECYSTECTOMY, LAPAROSCOPIC; FEMALE; HUMANS; ISOQUINOLINES; MALE; MIDDLE AGED; ONDANSETRON; POSTOPERATIVE NAUSEA AND VOMITING; QUINUCLIDINES; SEROTONIN ANTAGONISTS; SINGLE-BLIND METHOD; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84874824851     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.106430     Document Type: Article

References (29)

1. Islam S, Jain PN. Post-operative nausea and vomiting (PONV): A review article. Indian J Anaesth 2004;48:253-8.
2. Turkistani A, Abdullah K, Manaa E, Delvi B, Khairy G, Abdulghani B, et al. Effect of fl uid preloading on postoperative nausea and vomiting following laparoscopic cholecystectomy. Saudi J Anaesth 2009;3:48-52.
3. Grover VK, Mathew PJ, Hegde H. Effi cacy of orally disintegrating ondansetron in preventing postoperative nausea and vomiting after laparoscopic cholecystectomy: A randomised, double-blind placebo controlled study. Anaesthesia 2009;64:595-600.
4. Wallenborn J, Eberhart LH, Kranke P. Postoperative nausea and vomiting-what's new in anti-emetic pharmacotherapy [Article in German]. Anasthesiol Intensivmed Notfallmed Schmerzther 2009;44:296-304.
5. Kloth DD. New pharmacologic fi ndings for the treatment of PONV and PDNV. Am J Health Syst Pharm 2009;66(1 Suppl 1):S11-8.
6. Navari RM. Palonosetron: A second-generation 5-hydroxytryptamine receptor antagonist. Future Oncol 2006;2:591-602.
7. Rojas C, Stathis M, Thomas AG, Massuda EB, Alt J, Zhang J, et al. Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor. Anesth Analg 2008;107:469-78.
8. Muchatuta NA, Paech MJ. Management of postoperative nausea and vomiting: Focus on palonosetron. Ther Clin Risk Manag 2009;5:21-34.
9. Lerman J. Surgical and patient factors involved in postoperative nausea and vomiting. Br J Anaesth 1992;69(7 Suppl 1):24S-32.
10. Bunce KT, Tyers MB. The role of 5-HT in postoperative nausea and vomiting. Br J Anaesth 1992;69(7 Suppl 1):60S-2.
11. Watcha MF, White PF. Postoperative nausea and vomiting. Its etiology, treatment, and prevention. Anesthesiology 1992;77:162-84.
12. Gan TJ. Mechanisms underlying postoperative nausea and vomiting and neurotransmitter receptor antagonist-based pharmacotherapy. CNS Drugs 2007;21:813-33.
13. Apfel CC, Kranke P, Katz MH, Goepfert C, Papenfuss T, Rauch S, et al. Volatile anaesthetics may be the main cause of early but not delayed postoperative vomiting: A randomized controlled trial of factorial design. Br J Anaesth 2002;88:659-68.
14. Tramer M, Moore A, McQuay H. Omitting nitrous oxide in general anaesthesia: Meta-analysis of intraoperative awareness and postoperative emesis in randomized controlled trials. Br J Anaesth 1996;76:186-93.
15. Sinclair DR, Chung F, Mezei G. Can post-operative nausea and vomiting be predicted Anesthesiology 1999;91:109-18.
16. Koivuranta M, Laara E, Snare L, Alahuhta S. A survey of postoperative nausea and vomiting. Anaesthesia 1997;52:443-9.
17. Gan TJ. Selective serotonin 5-HT3 receptor antagonists for postoperative nausea and vomiting: are they all the same CNS Drugs 2005;19:225-38.
18. Ho KY, Gan TJ. Pharmacology, pharmacogenetics, and clinical effi cacy of 5-hydroxytryptamine type 3 receptor antagonists for postoperative nausea and vomiting. Curr Opin Anaesthesiol 2006;19:606-11.
19. Helmers JH, Briggs L, Abrahamsson J, Soni J, Moodley J, Forrler M, et al. A single i.v. dose of ondansetron 8 mg prior to induction of anaesthesia reduces postoperative nausea and vomiting in gynaecological patients. Can J Anaesth 1993;40:1155-61.
20. Candiotti KA, Kovac AL, Melson TI, Clerici G, Joo Gan T. A randomized, doubleblind, study to evaluate the effi cacy and safety of 3 different doses of palonosetron versus placebo in preventing postoperative and postdischarge nausea and vomiting. Anesth Analg 2008;107:445-51.
21. Kovac AL, Eberhart L, Kotarski J, Clerici G, Apfel C. A randomized, double-blind study to evaluate the effi cacy and safety of three different doses of palonosetron versus placebo in preventing postoperative nausea and vomiting over a 72-hour period. Anesth Analg 2008;107:439-44.
22. Aspinall RL, Goodman NW. Denial of effective treatment and poor quality of clinical information in placebo controlled trials of ondansetron for postoperative nausea and vomiting: A review of published trials. Br Med J 1995;311:844-6.
23. Moon YE, Joo J, Kim JE, Lee Y. Antiemetic effect of ondansetron and palonosetron in thyroidectomy: A prospective, randomized, double-blind study. Br J Anaesth 2012;108:417-22.
24. Basu A, Saha D, Hembrom BP, Roy A, Naaz A. Comparison of palanosetron, granisetron and ondansetron as anti-emetics for prevention of postoperative nausea and vomiting in patients undergoing middle ear surgery. J Indian Med Assoc 2011;109:327-9.
25. Bajwa SS, Bajwa SK, Kaur J, Sharma V, Singh A, Singh A, et al. Palonosetron: A novel approach to control postoperative nausea and vomiting in day care surgery. Saudi J Anaesth 2011;5:19-24.
26. Park SK, Cho EJ. A randomized, double-blind trial of palonosetron compared with ondansetron in preventing postoperative nausea and vomiting after gynaecological laparoscopic surgery. J Int Med Res 2011;39:399-407.
27. Bhattacharjee DP, Dawn S, Nayak S, Roy PR, Acharya A, Dey R. A comparative study between palonosetron and granisetron to prevent postoperative nausea and vomiting after laparoscopic cholecystectomy. J Anaesthesiol Clin Pharmacol 2010;26:480-3.
28. Charbit B, Albaladejo P, Funck-Brentano C, Legrand M, Samain E, Marty J. Prolongation of QTc interval after postoperative nausea and vomiting treatment by droperidol or ondansetron. Anesthesiology 2005;102:1094-100.
29. McKechnie K, Froese A. Ventricular tachycardia after ondansetron administration in a child with undiagnosed long QT syndrome. Can J Anaesth 2010;57: 453-7.