A randomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo in preventing postoperative nausea and vomiting over a 72-hour period

Anesthesia and Analgesia

Volumn 107, Issue 2, 2008, Pages 439-444

  Kovac, Anthony L ^a   Eberhart, Leopold ^b   Kotarski, Jan ^c   Clerici, Giuseppina ^d,f   Apfel, Christian ^e  

^a Department of Anesthesiology   (United States)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^d HELSINN HEALTHCARE SA   (Switzerland)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f NONE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

PALONOSETRON; PLACEBO; ANTIEMETIC AGENT; ISOQUINOLINE DERIVATIVE; QUINUCLIDINE DERIVATIVE; SEROTONIN ANTAGONIST;

ADULT; ANESTHESIA INDUCTION; ARTICLE; BREAST SURGERY; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SAFETY; FEMALE; GYNECOLOGIC SURGERY; HUMAN; MAJOR CLINICAL STUDY; MOTION SICKNESS; MULTICENTER STUDY; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; QT PROLONGATION; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; STATISTICAL SIGNIFICANCE; TREATMENT FAILURE; ADOLESCENT; AGED; BREAST; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIEMETICS; BREAST; DOUBLE-BLIND METHOD; FEMALE; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; INJECTIONS, INTRAVENOUS; ISOQUINOLINES; MIDDLE AGED; POSTOPERATIVE NAUSEA AND VOMITING; QUINUCLIDINES; SEROTONIN ANTAGONISTS; TREATMENT FAILURE;

EID: 49949106632     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e31817abcd3     Document Type: Article

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