Hepatic stellate cells support hematopoiesis and are liver-resident mesenchymal stem cells

Cellular Physiology and Biochemistry

Volumn 31, Issue 2-3, 2013, Pages 290-304

  Kordes, Claus ^a   Sawitza, Iris ^a   Götze, Silke ^a   Häussinger, Dieter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Bone marrow mesenchymal stem cells; Extramedullary hematopoiesis; Fetal liver; Hepatic stellate cells; Liver pericytes; Nestin

Indexed keywords

DESMIN; MOLECULAR MARKER; STEM CELL ANTIGEN 1;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BLOOD CELL; BONE MARROW CELL; CELL DIFFERENTIATION; CELL ISOLATION; CELL LINEAGE; CELL SELECTION; CONTROLLED STUDY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; LIVER CELL; MALE; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOCYTE; PRIORITY JOURNAL; RAT; STELLATE CELL; STEM CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BONE MARROW DERIVED MESENCHYMAL STEM CELL; COCULTURE; CYTOCHEMISTRY; IMMUNOFLUORESCENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WHOLE CELL;

MURINAE; RATTUS;

EID: 84874799703     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000343368     Document Type: Article

References (35)

1. Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden DT: Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003;425:841-846. (Pubitemid 37351468)
2. Kiel MJ, Yilmaz OH, Iwashita T, Terhorst C, Morrison SJ: SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 2005;121:1109-1121. (Pubitemid 40884400)
3. Katayama Y, Battista M, Kao W-M, Hidalgo A, Peired AJ, Thomas SA, Frenette PS: Signals from the sympathic nervous system regulate hematopoietic stem cell egress from the bone marrow. Cell 2006;124:407-421. (Pubitemid 43121987)
4. Mendez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Maayan A, Enikolopov GN, Frenette PS: Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 2010;466:829-834.
5. Hackney JA, Charbord P, BrunkBP, Stoeckert CJ, Lemischka IR, Moore KA: A molecular profile of a hematopoietic stem cell niche. Proc Natl Acad Sci USA 2002;99:13061-13066.
6. Martin MA, Bhatia M: Analysis of the human fetal liver hematopoietic microenvironment. Stem Cells Dev 2005;14:493-504. (Pubitemid 41780802)
7. Kiassov AP, Van Eyken P, Van Pelt JF, Depla E, Fevery J, Desmet VJ, Yap SH: Desmin expressing nonhematopoietic liver cells during rat liver development: an immunohistochemical and morphometric study. Differentiation 1995;59:253-258. (Pubitemid 26004223)
8. Kubota H, Yao HL, Reid LM: Identification and characterization of vitamin A-storing cells in fetal liver: implications for functional importance of hepatic stellate cells in liver development and hematopoiesis. Stem Cells 2007;25:2339-2349. (Pubitemid 47480493)
9. Kordes C, Sawitza I, Miiller-Marbach A, Ale-Agha N, Keitel V, Klonowski-Stumpe H, Haussinger D: CD133 + hepatic stellate cells are progenitor cells. Biochem Biophys Res Commun 2007;352:410-417. (Pubitemid 44838502)
10. Kordes C, Sawitza I, Gotze S, Haussinger D: Stellate cells from rat pancreas are stem cells and can contribute to liver regeneration. PLoS One 2012;7:e51878.
11. Spangrude GJ, Heimfeld S, Weissman IL: Purification and characterization of mouse hematopoietic stem cells. Science 1988;241:58-62.
12. Akashi K, Traver D, Miyamoto T, Weissman IL: A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 2000;404:193-197. (Pubitemid 30154488)
13. Hendriks HFJ, Verhoofstad WA, Brouwer A, de Leeuw AM, Knook DL: Perisinusoidal fat-storing cells are the main vitamin A storage sites in rat liver. Exp Cell Res 1985;160:138-149. (Pubitemid 16227414)
14. Knook DL, Sleyster EC: Separation of Kupffer and endothelial cells of the rat liver by centrifugal elutriation. Exp Cell Res 1976;99:444-449.
15. Berry MN, Friend DS: High-yield preparation of isolated rat liver parenchymal cells. A biochemical and fine structural study. J Cell Biol 1969;43:506-520.
16. Metcalf D: Hematopoietic cytokines. Blood 2008;111:485-491.
17. Maxwell PH, Ferguson DJ, Osmond MK, Pugh CW, Heryet A, Doe BG, Johnson MH, Ratcliffe PJ: Expression of a homologously recombined erythopoietin-SV40 T antigen fusion gene in mouse liver: evidence for erythropoietin production by Ito cells. Blood 1994;84:1823-1830. (Pubitemid 24286131)
18. Xue Y, Lim S, Yang Y, Wang Z, Jensen LD, Hedlund EM, Andersson P, Sasahara M, Larsson 0, Gaiter D, Cao R, Hosaka K, Cao Y: PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells. Nat Med 2011;18:100-110.
19. Purton LE, Bernstein ID, Collins SJ: All-trans retinoic acid delays the differentiation of primitive hematopoietic precursors (lin-c-kit+Sca-1+) while enhancing the terminal maturation of committed granulocyte/monocyte progenitors. Blood 1999;94:483-495. (Pubitemid 29323863)
20. Sawitza I, Kordes C, Reister S, Haussinger D: The niche of stellate cells within rat liver. Hepatology 2009;50:1617-1624.
21. Athari A, Hanecke K, Jungermann K: Prostaglandin F2alpha and D2 release from primary Ito cell cultures after stimulation with noradrenaline and ATP but not adenosine. Hepatology 1994;20:142-148.
22. vom Dahl S, Bode JG, Reinehr R, Monnighoff I, Kubitz R, Haussinger D: Release of osmolytes from perfused rat liver on perivascular nerve stimulation: alpha-adrenergic control of osmolyte efflux from parenchymal and nonparenchymal liver cells. Hepatology 1999;1:195-204. (Pubitemid 29024003)
23. McCuskey RS: Anatomy of efferent hepatic nerves. Anat Rec A Discov Mol Cell Evol Biol 2004;280:821-826. (Pubitemid 39330961)
24. Ramadori G, Neubauer K, Odenthal M, Nakamura T, Knittel T, Schwogler S, Meyer zum Biischenfelde KH: The gene of hepatocyte growth factor is expressed in fat-storing cells of rat liver and is downregulated during cell growth and by transforming growth factor-beta. Biochem Biophys Res Commun 1992; 183:739-742.
25. Aleffi S, Petrai I, Bertolani C, Parola M, Colombatto S, Novo E, Vizzutti F, Anania FA, Milani S, Rombouts K, Laffi G, Pinzani M, Marra F: Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells. Hepatology 2005;42:1339-1348. (Pubitemid 43260036)
26. Crisostomo PR, Wang Y, Markel TA, Wang M, Lahm T, Meldrum DR: Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an NF kappa B-but not JNK-dependent mechanism. Am J Physiol Cell Physiol 2008;294:C675-682. (Pubitemid 351468685)
27. Taura K, De Minicis S, Seki E, Hatano E, Iwaisako K, Osterreicher CH, Kodama Y, Miura K, Ikai I, Uemoto S, Brenner DA: Hepatic stellate cells secrete angiopoietin 1 that induces angiogenesis in liver fibrosis. Gastroenterology 2008;135:1729-1738.
28. Torimura T, Ueno T, Kin M, Harada R, Taniguchi E, Nakamura T, Sakata R, Hashimoto 0, Sakamoto M, Kumashiro R, Sata M, Nakashima 0, Yano H, Kojiro M: Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma. J Hepatol 2004;40:799-807. (Pubitemid 38507361)
29. Castilho-Fernandes A, de Almeida DC, Fontes AM, Melo FU, Picanco-Castro V, Freitas MC, Orellana MD, Palma PV, Hackett PB, Friedman SL, Covas DT: Human hepatic stellate cell line (LX-2) exhibits characteristics of bone marrow-derived mesenchymal stem cells. Exp Mol Pathol 2011;91:664-672.
30. Crisan M, Yap S, Casteilla L, Chen CW, Corselli M, Park TS, Andriolo G, Sun B, Zheng B, Zhang L, Norotte C, Teng PN, Traas J, Schugar R, Deasy BM, Badylak S, Buhring HJ, Giacobino JP, Lazzari L, Huard J, Peault B: A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 2008;3:301-313.
31. Chamberlain G, Fox J, Ashton B, Middleton J: Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells 2007;25:2739-2749. (Pubitemid 350127858)
32. de Hemptinne I, Vermeiren C, Maloteaux JM, Hermans E: Induction of glial glutamate transporters in adult mesenchymal stem cells. J Neurochem 2004;91:155-166. (Pubitemid 39314946)
33. Tondreau T, Meuleman N, Delforge A, Dejeneffe M, Leroy R, Massy M, Mortier C, Bron D, Lagneaux L: Mesenchymal stem cells derived from CD133-positive cells in mobilized peripheral blood and cord blood: proliferation, 0ct4 expression, and plasticity. Stem Cells 2005;23:1105-1112. (Pubitemid 41377726)
34. Pozzobon M, Piccoli M, Ditadi A, Bollini S, Destro R, Andre-Schmutz I, Masiero L, Lenzini E, Zanesco L, Petrelli L, Cavazzana-Calvo M, Gazzola MV, De Coppi P: Mesenchymal stromal cells can be derived from bone marrow CD133+ cells: implications for therapy. Stem Cells Dev 2009;18:497-510.
35. Lepperdinger G: Inflammation and mesenchymal stem cell aging. Curr Opin Immunol 2011;23:518-524.