Integration, stability and expression of the E. coli phytase transgene in the Cassie line of Yorkshire Enviropig™

Transgenic Research

Volumn 22, Issue 2, 2013, Pages 379-389

  Forsberg, Cecil W ^a   Meidinger, Roy G ^a   Liu, Mingfu ^b   Cottrill, Michael ^a   Golovan, Serguei ^c   Phillips, John P ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b HARBOR UCLA MEDICAL CENTER   (United States)

^c UNIVERSITY OF DELAWARE   (United States)

Author keywords

Phosphorus; Phytase; Porcine; Saliva; Transgenic

Indexed keywords

EID: 84874797089     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11248-012-9646-7     Document Type: Article

References (24)

1. Bishop JO (1996) Chromosomal insertion of foreign DNA. Reprod Nutr Dev 36: 607-618.
2. Brinster RL, Chen HY, Trumbauer ME, Yagle MK (1985) Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proc Natl Acad Sci USA 82: 4438-4442.
3. Carpenter SR (2008) Phosphorus control is critical to mitigating eutrophication. Proc Natl Acad Sci USA 105: 11039-11040.
4. Corring T (1980) Endogenous secretions in the pig. In: Low AG, Partridge IG (eds) Current concepts of digestion and absorption in pigs. National Institute for Research in Dairying, Reading, pp 136-150.
5. Covarrubias L, Nishida Y, Terao M, D'Eustachio P, Mintz B (1987) Cellular DNA rearrangements and early developmental arrest caused by DNA insertion in transgenic mouse embryos. Mol Cell Biol 7: 2243-2247.
6. Ewing B, Green P (1998) Base-calling of automated sequencer traces using phred. II. Error probabilities. Genome Res 8: 186-194.
7. Ewing B, Hillier L, Wendl MC, Green P (1998) Base-calling of automated sequencer traces using Phred. I. Accuracy assessment. Genome Res 8: 175-185.
8. Garrick D, Fiering S, Martin DIK, Whitelaw E (1998) Repeat-induced gene silencing in mammals. Nat Genet 18: 56-59.
9. Gerber PJ, Vellinga TV, Steinfeld H (2010) Issues and options in addressing the environmental consequences of livestock sector's growth. Meat Sci 84: 244-247.
10. Golovan S, Wang G, Zhang J, Forsberg CW (2000) Characterization and overproduction of the Escherichia coliappA encoded bifunctional enzyme which exhibits both phytase and acid phosphatase activities. Can J Microbiol 46: 59-71.
11. Golovan SP, Hayes MA, Phillips JP, Forsberg CW (2001a) Transgenic mice expressing bacterial phytase as a model for phosphorus pollution control. Nat Biotechnol 19: 429-433.
12. Golovan SP, Meidinger RG, Ajakaiye A, Cottrill M, Wiederkehr MZ, Barney D, Plante C, Pollard J, Fan MZ, Hayes MA, Laursen J, Hjorth JP, Hacker RR, Phillips JP, Forsberg CW (2001b) Pigs expressing salivary phytase produce low phosphorus manure. Nat Biotechnol 19: 741-745.
13. Hamada T, Sasaki H, Seki R, Sakaki Y (1993) Mechanism of chromosomal integration of transgenes in microinjected mouse eggs: sequence analysis of genome-transgene and transgene-transgene junctions at two loci. Gene 128: 197-202.
14. Hammer RE, Pursel VG, Rexroad CE Jr, Wall RJ, Bolt DJ, Ebert KM, Palmiter RD, Brinster RL (1985) Production of transgenic rabbits, sheep and pigs by microinjection. Nature 315: 680-683.
15. Higuchi R (1989) Simple and rapid preparation of samples for PCR. In: Erlich HA (ed) PCR technology: principles and applications for DNA amplification. MacMillan Publishers; Stockton Press, New York, pp 31-38.
16. Key N, McBride WD, Ribaudo M, Sneeringer S (2011) Trends and developments in hog manure management: 1998-2009. 81: 1-33. USDA (http://www. ers. usda. gov/Publications/EIB81/).
17. Lam JS, Mutharia LM (1994) Antigen-antibody reactions. In: Gerhardt P, Murray RGE, Wood WA, Krieg NR (eds) Methods for general and molecular bacteriology. American Society for Microbiology, Washington DC, pp 104-132.
18. Rohan RM, King D, Frels WI (1990) Direct sequencing of PCR-amplified junction fragments from tandemly repeated transgenes. Nucleic Acids Res 18: 6089-6095.
19. Sharma PL, Nurpeisov V, Schinazi RF (2005) Retrovirus reverse transcriptases containing a modified YXDD motif. Antivir Chem Chemother 16: 169-182.
20. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC (1985) Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85.
21. Sommer JR, Wong F, Petters RM (2011) Phenotypic stability of Pro347Leu rhodopsin transgenic pigs as indicated by photoreceptor cell degeneration. Transgenic Res 20: 1391-1395.
22. Viveros A, Centeno C, Brenes A, Canales R, Lozano A (2000) Phytase and acid phosphatase activities in plant feedstuffs. J Agric Food Chem 48: 4009-4013.
23. Wagner EF, Stewart TA, Mintz B (1981) The human beta-globin gene and a functional viral thymidine kinase gene in developing mice. Proc Natl Acad Sci USA 78: 5016-5020.
24. Wurtele H, Little KC, Chartrand P (2003) Illegitimate DNA integration in mammalian cells. Gene Ther 10: 1791-1799.