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Volumn 3, Issue 2, 2013, Pages 195-204

Immunotoxin targeting CD133+ breast carcinoma cells

Author keywords

Breast cancer; Cancer stem cells; CD133; Immunotoxin; Pseudomonas exotoxin; Xenograft model

Indexed keywords

ANTINEOPLASTIC AGENT; CD133 ANTIGEN; IMMUNOTOXIN; IMMUNOTOXIN DCD133KDEL; UNCLASSIFIED DRUG;

EID: 84874794401     PISSN: 2190393X     EISSN: 21903948     Source Type: Journal    
DOI: 10.1007/s13346-012-0066-2     Document Type: Article
Times cited : (33)

References (47)
  • 1
    • 5444256238 scopus 로고    scopus 로고
    • Self-renewal and solid tumor stem cells
    • Al-Hajj M, Clarke MF. Self-renewal and solid tumor stem cells. Oncogene. 2004; 23(43): 7274-82.
    • (2004) Oncogene , vol.23 , Issue.43 , pp. 7274-7282
    • Al-Hajj, M.1    Clarke, M.F.2
  • 2
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001; 414(6859): 105-11.
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 3
    • 45549093647 scopus 로고    scopus 로고
    • Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis
    • Eyler CE, Rich JN. Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis. J Clin Oncol. 2008; 26(17): 2839-45.
    • (2008) J Clin Oncol , vol.26 , Issue.17 , pp. 2839-2845
    • Eyler, C.E.1    Rich, J.N.2
  • 4
    • 45549096766 scopus 로고    scopus 로고
    • Cancer stem cells: a step toward the cure
    • Boman BM, Wicha MS. Cancer stem cells: a step toward the cure. J Clin Oncol. 2008; 26(17): 2795-9.
    • (2008) J Clin Oncol , vol.26 , Issue.17 , pp. 2795-2799
    • Boman, B.M.1    Wicha, M.S.2
  • 5
    • 65649087098 scopus 로고    scopus 로고
    • Breast cancer: understanding sensitivity and resistance to chemotherapy and targeted therapies to aid in personalised medicine
    • Germano S, O'Driscoll L. Breast cancer: understanding sensitivity and resistance to chemotherapy and targeted therapies to aid in personalised medicine. Curr Cancer Drug Targets. 2009; 9(3): 398-418.
    • (2009) Curr Cancer Drug Targets , vol.9 , Issue.3 , pp. 398-418
    • Germano, S.1    O'Driscoll, L.2
  • 7
    • 0032055819 scopus 로고    scopus 로고
    • AC133 hematopoietic stem cell antigen: human homologue of mouse kidney prominin or distinct member of a novel protein family?
    • Corbeil D, Roper K, Weigmann A, Huttner WB. AC133 hematopoietic stem cell antigen: human homologue of mouse kidney prominin or distinct member of a novel protein family? Blood. 1998; 91(7): 2625-6.
    • (1998) Blood , vol.91 , Issue.7 , pp. 2625-2626
    • Corbeil, D.1    Roper, K.2    Weigmann, A.3    Huttner, W.B.4
  • 8
    • 0039765237 scopus 로고    scopus 로고
    • The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions
    • Corbeil D, Roper K, Hellwig A, Tavian M, Miraglia S, Watt SM, et al. The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions. J Biol Chem. 2000; 275(8): 5512-20.
    • (2000) J Biol Chem , vol.275 , Issue.8 , pp. 5512-5520
    • Corbeil, D.1    Roper, K.2    Hellwig, A.3    Tavian, M.4    Miraglia, S.5    Watt, S.M.6
  • 9
    • 0031453534 scopus 로고    scopus 로고
    • AC133, a novel marker for human hematopoietic stem and progenitor cells
    • Yin AH, Miraglia S, Zanjani ED, Almeida-Porada G, Ogawa M, Leary AG, et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood. 1997; 90(12): 5002-12.
    • (1997) Blood , vol.90 , Issue.12 , pp. 5002-5012
    • Yin, A.H.1    Miraglia, S.2    Zanjani, E.D.3    Almeida-Porada, G.4    Ogawa, M.5    Leary, A.G.6
  • 10
    • 12944253116 scopus 로고    scopus 로고
    • Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors
    • Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood. 2000; 95(3): 952-8.
    • (2000) Blood , vol.95 , Issue.3 , pp. 952-958
    • Peichev, M.1    Naiyer, A.J.2    Pereira, D.3    Zhu, Z.4    Lane, W.J.5    Williams, M.6
  • 13
    • 35349017905 scopus 로고    scopus 로고
    • Stem cell patterns in cell lines derived from head and neck squamous cell carcinoma
    • Harper LJ, Piper K, Common J, Fortune F, Mackenzie IC. Stem cell patterns in cell lines derived from head and neck squamous cell carcinoma. J Oral Pathol Med. 2007; 36(10): 594-603.
    • (2007) J Oral Pathol Med , vol.36 , Issue.10 , pp. 594-603
    • Harper, L.J.1    Piper, K.2    Common, J.3    Fortune, F.4    Mackenzie, I.C.5
  • 14
    • 79952453864 scopus 로고    scopus 로고
    • Pancreatic cancer cells resistant to chemoradiotherapy rich in "stem-cell-like" tumor cells
    • Du Z, Qin R, Wei C, Wang M, Shi C, Tian R, et al. Pancreatic cancer cells resistant to chemoradiotherapy rich in "stem-cell-like" tumor cells. Dig Dis Sci. 2010; 56(3): 741-50.
    • (2010) Dig Dis Sci , vol.56 , Issue.3 , pp. 741-750
    • Du, Z.1    Qin, R.2    Wei, C.3    Wang, M.4    Shi, C.5    Tian, R.6
  • 20
    • 54249143589 scopus 로고    scopus 로고
    • Cell cycle-dependent variation of a CD133 epitope in human embryonic stem cell, colon cancer, and melanoma cell lines
    • Jaksch M, Munera J, Bajpai R, Terskikh A, Oshima RG. Cell cycle-dependent variation of a CD133 epitope in human embryonic stem cell, colon cancer, and melanoma cell lines. Cancer Res. 2008; 68(19): 7882-6.
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 7882-7886
    • Jaksch, M.1    Munera, J.2    Bajpai, R.3    Terskikh, A.4    Oshima, R.G.5
  • 21
    • 49749144107 scopus 로고    scopus 로고
    • The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells
    • Bidlingmaier S, Zhu X, Liu B. The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells. J Mol Med (Berl). 2008; 86(9): 1025-32.
    • (2008) J Mol Med (Berl) , vol.86 , Issue.9 , pp. 1025-1032
    • Bidlingmaier, S.1    Zhu, X.2    Liu, B.3
  • 22
    • 76549120193 scopus 로고    scopus 로고
    • The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation
    • Kemper K, Sprick MR, de Bree M, Scopelliti A, Vermeulen L, Hoek M, et al. The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. Cancer Res. 2010; 70(2): 719-29.
    • (2010) Cancer Res , vol.70 , Issue.2 , pp. 719-729
    • Kemper, K.1    Sprick, M.R.2    de Bree, M.3    Scopelliti, A.4    Vermeulen, L.5    Hoek, M.6
  • 25
    • 36148995870 scopus 로고    scopus 로고
    • Influence of oxygen tension on CD133 phenotype in human glioma cell cultures
    • Platet N, Liu SY, Atifi ME, Oliver L, Vallette FM, Berger F, et al. Influence of oxygen tension on CD133 phenotype in human glioma cell cultures. Cancer Lett. 2007; 258(2): 286-90.
    • (2007) Cancer Lett , vol.258 , Issue.2 , pp. 286-290
    • Platet, N.1    Liu, S.Y.2    Atifi, M.E.3    Oliver, L.4    Vallette, F.M.5    Berger, F.6
  • 29
    • 0024426607 scopus 로고
    • Targeted toxin therapy for the treatment of cancer
    • FitzGerald D, Pastan I. Targeted toxin therapy for the treatment of cancer. J Natl Cancer Inst. 1989; 81(19): 1455-63.
    • (1989) J Natl Cancer Inst , vol.81 , Issue.19 , pp. 1455-1463
    • FitzGerald, D.1    Pastan, I.2
  • 30
    • 0032032442 scopus 로고    scopus 로고
    • Accumulation of a recombinant immunotoxin in a tumor in vivo: fewer than 1000 molecules per cell are sufficient for complete responses
    • Kreitman RJ, Pastan I. Accumulation of a recombinant immunotoxin in a tumor in vivo: fewer than 1000 molecules per cell are sufficient for complete responses. Cancer Res. 1998; 58(5): 968-75.
    • (1998) Cancer Res , vol.58 , Issue.5 , pp. 968-975
    • Kreitman, R.J.1    Pastan, I.2
  • 31
    • 0028951457 scopus 로고
    • Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor
    • Kreitman RJ, Pastan I. Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor. Biochem J. 1995; 307(Pt 1): 29-37.
    • (1995) Biochem J , vol.307 , Issue.Pt 1 , pp. 29-37
    • Kreitman, R.J.1    Pastan, I.2
  • 32
    • 67649933809 scopus 로고    scopus 로고
    • Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemia
    • Kreitman RJ, Stetler-Stevenson M, Margulies I, Noel P, Fitzgerald DJ, Wilson WH, et al. Phase II trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with hairy cell leukemia. J Clin Oncol. 2009; 27(18): 2983-90.
    • (2009) J Clin Oncol , vol.27 , Issue.18 , pp. 2983-2990
    • Kreitman, R.J.1    Stetler-Stevenson, M.2    Margulies, I.3    Noel, P.4    Fitzgerald, D.J.5    Wilson, W.H.6
  • 33
    • 70349653790 scopus 로고    scopus 로고
    • A novel reduced immunogenicity bispecific targeted toxin simultaneously recognizing human epidermal growth factor and interleukin-4 receptors in a mouse model of metastatic breast carcinoma
    • Oh S, Stish BJ, Sachdev D, Chen H, Dudek AZ, Vallera DA. A novel reduced immunogenicity bispecific targeted toxin simultaneously recognizing human epidermal growth factor and interleukin-4 receptors in a mouse model of metastatic breast carcinoma. Clin Cancer Res. 2009; 15(19): 6137-47.
    • (2009) Clin Cancer Res , vol.15 , Issue.19 , pp. 6137-6147
    • Oh, S.1    Stish, B.J.2    Sachdev, D.3    Chen, H.4    Dudek, A.Z.5    Vallera, D.A.6
  • 34
    • 70349655268 scopus 로고    scopus 로고
    • Design and modification of EGF4KDEL 7Mut, a novel bispecific ligand-directed toxin, with decreased immunogenicity and potent anti-mesothelioma activity
    • Stish BJ, Oh S, Chen H, Dudek AZ, Kratzke RA, Vallera DA. Design and modification of EGF4KDEL 7Mut, a novel bispecific ligand-directed toxin, with decreased immunogenicity and potent anti-mesothelioma activity. Br J Cancer. 2009; 101(7): 1114-23.
    • (2009) Br J Cancer , vol.101 , Issue.7 , pp. 1114-1123
    • Stish, B.J.1    Oh, S.2    Chen, H.3    Dudek, A.Z.4    Kratzke, R.A.5    Vallera, D.A.6
  • 35
    • 49649091350 scopus 로고    scopus 로고
    • An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes
    • Onda M, Beers R, Xiang L, Nagata S, Wang QC, Pastan I. An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes. Proc Natl Acad Sci U S A. 2008; 105(32): 11311-6.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.32 , pp. 11311-11316
    • Onda, M.1    Beers, R.2    Xiang, L.3    Nagata, S.4    Wang, Q.C.5    Pastan, I.6
  • 36
    • 33845457606 scopus 로고    scopus 로고
    • Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients
    • Onda M, Nagata S, FitzGerald DJ, Beers R, Fisher RJ, Vincent JJ, et al. Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients. J Immunol. 2006; 177(12): 8822-34.
    • (2006) J Immunol , vol.177 , Issue.12 , pp. 8822-8834
    • Onda, M.1    Nagata, S.2    FitzGerald, D.J.3    Beers, R.4    Fisher, R.J.5    Vincent, J.J.6
  • 37
    • 80054003177 scopus 로고    scopus 로고
    • Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancer
    • Waldron NN, Kaufman DS, Oh S, Inde Z, Hexum MK, Ohlfest JR, et al. Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancer. Mol Cancer Ther. 2011; 10(10): 1829-38.
    • (2011) Mol Cancer Ther , vol.10 , Issue.10 , pp. 1829-1838
    • Waldron, N.N.1    Kaufman, D.S.2    Oh, S.3    Inde, Z.4    Hexum, M.K.5    Ohlfest, J.R.6
  • 38
    • 77953435950 scopus 로고    scopus 로고
    • Bioengineering a unique deimmunized bispecific targeted toxin that simultaneously recognizes human CD22 and CD19 receptors in a mouse model of B-cell metastases
    • Vallera DA, Oh S, Chen H, Shu Y, Frankel AE. Bioengineering a unique deimmunized bispecific targeted toxin that simultaneously recognizes human CD22 and CD19 receptors in a mouse model of B-cell metastases. Mol Cancer Ther. 2010; 9(6): 1872-83.
    • (2010) Mol Cancer Ther , vol.9 , Issue.6 , pp. 1872-1883
    • Vallera, D.A.1    Oh, S.2    Chen, H.3    Shu, Y.4    Frankel, A.E.5
  • 39
    • 0015945729 scopus 로고
    • Establishment of epithelial cell line MDA-MB-157 from metastatic pleural effusion of human breast carcinoma
    • Young RK, Cailleau RM, Mackay B, Reeves Jr WJ. Establishment of epithelial cell line MDA-MB-157 from metastatic pleural effusion of human breast carcinoma. In Vitro. 1974; 9(4): 239-45.
    • (1974) In Vitro , vol.9 , Issue.4 , pp. 239-245
    • Young, R.K.1    Cailleau, R.M.2    Mackay, B.3    Reeves Jr., W.J.4
  • 40
    • 49149107236 scopus 로고    scopus 로고
    • Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy
    • Dylla SJ, Beviglia L, Park IK, Chartier C, Raval J, Ngan L, et al. Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. PLoS One. 2008; 3(6): e2428.
    • (2008) PLoS One , vol.3 , Issue.6
    • Dylla, S.J.1    Beviglia, L.2    Park, I.K.3    Chartier, C.4    Raval, J.5    Ngan, L.6
  • 41
    • 62449205665 scopus 로고    scopus 로고
    • Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
    • Dallas NA, Xia L, Fan F, Gray MJ, Gaur P, van Buren 2nd G, et al. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res. 2009; 69(5): 1951-7.
    • (2009) Cancer Res , vol.69 , Issue.5 , pp. 1951-1957
    • Dallas, N.A.1    Xia, L.2    Fan, F.3    Gray, M.J.4    Gaur, P.5    van Buren 2nd, G.6
  • 42
    • 12144263254 scopus 로고    scopus 로고
    • Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer
    • Florek M, Haase M, Marzesco AM, Freund D, Ehninger G, Huttner WB, et al. Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer. Cell Tissue Res. 2005; 319(1): 15-26.
    • (2005) Cell Tissue Res , vol.319 , Issue.1 , pp. 15-26
    • Florek, M.1    Haase, M.2    Marzesco, A.M.3    Freund, D.4    Ehninger, G.5    Huttner, W.B.6
  • 43
    • 0030817282 scopus 로고    scopus 로고
    • Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells
    • Weigmann A, Corbeil D, Hellwig A, Huttner WB. Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc Natl Acad Sci U S A. 1997; 94(23): 12425-30.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.23 , pp. 12425-12430
    • Weigmann, A.1    Corbeil, D.2    Hellwig, A.3    Huttner, W.B.4
  • 44
    • 46349107401 scopus 로고    scopus 로고
    • CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers
    • Smith LM, Nesterova A, Ryan MC, Duniho S, Jonas M, Anderson M, et al. CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers. Br J Cancer. 2008; 99(1): 100-9.
    • (2008) Br J Cancer , vol.99 , Issue.1 , pp. 100-109
    • Smith, L.M.1    Nesterova, A.2    Ryan, M.C.3    Duniho, S.4    Jonas, M.5    Anderson, M.6
  • 45
    • 78149479157 scopus 로고    scopus 로고
    • Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma
    • Kunwar S, Chang S, Westphal M, Vogelbaum M, Sampson J, Barnett G, et al. Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma. Neuro Oncol. 2010; 12(8): 871-81.
    • (2010) Neuro Oncol , vol.12 , Issue.8 , pp. 871-881
    • Kunwar, S.1    Chang, S.2    Westphal, M.3    Vogelbaum, M.4    Sampson, J.5    Barnett, G.6


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