Antibiotic resistance in pseudomonas aeruginosa is associated with decreased fitness

Cellular Physiology and Biochemistry

Volumn 31, Issue 2-3, 2013, Pages 347-354

  Sun, Zhenzhen ^a,b   Jiao, Xiaoyang ^b   Peng, Qing ^b   Jiang, Fang ^b   Huang, Yuanchun ^b   Zhang, Juan ^b   Yao, Fen ^b  

^a HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

Bacterial resistance; Nosocomial infection; Pseudomonas aeruginosa; lactam antibiotics

Indexed keywords

BETA LACTAM ANTIBIOTIC; ELASTASE; PROTEINASE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BIOFILM; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; FITNESS; GROWTH RATE; HEALTH CARE COST; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; HOSPITAL INFECTION; NONHUMAN; PROTEIN DEGRADATION; RANDOM AMPLIFIED POLYMORPHIC DNA;

BACTERIA (MICROORGANISMS); PSEUDOMONAS AERUGINOSA;

EID: 84874794063     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000343372     Document Type: Article

References (31)

1. Van Eldere J: Multicentre surveillance of pseudomonas aeruginosa susceptibility patterns in nosocomial infections. J Antimicrob Chemother 2003;51:347-352. (Pubitemid 36231155)
2. Richards MJ, Edwards JR, Culver DH, Gaynes RP: Nosocomial infections in medical intensive care units in the united states. National nosocomial infections surveillance system. Crit Care Med 1999;27:887-892. (Pubitemid 29266004)
3. Wang H, Chen MJ: Changes of antimicrobial resistance among nonfermenting gram-negative bacilli isolated from intensive care units from 1994 to 2001 in china. Zhonghua Yi Xue Za Zhi 2003;83:385-390.
4. El Solh AA, Alhajhusain A: Update on the treatment of pseudomonas aeruginosa pneumonia. J Antimicrob Chemother 2009;64:229-238.
5. Ullah F, Malik SA, Ahmed J: Antimicrobial susceptibility and esbl prevalence in pseudomonas aeruginosa isolated from burn patients in the north west of pakistan. Burns 2009;35:1020-1025.
6. Jones RN, Stilwell MG, Rhomberg PR, Sader HS: Antipseudomonal activity of piperacillin/tazobactam: More than a decade of experience from the sentry antimicrobial surveillance program (1997-2007). Diagn Microbiol Infect Dis 2009;65:331-334.
7. Shahcheraghi F, Nikbin VS, Feizabadi MM: Prevalence of esbls genes among multidrug-resistant isolates of pseudomonas aeruginosa isolated from patients in tehran. Microb Drug Resist 2009;15:37-39.
8. Hoiby N: Antibiotic therapy for chronic infection of pseudomonas in the lung. Annu Rev Med 1993;44:1-10. (Pubitemid 23117843)
9. Mulcahy H, O'Callaghan J, O'Grady EP, Macia MD, Borrell N, Gomez C, Casey PG, Hill C, Adams C, Gahan CG, Oliver A, O'Gara F: Pseudomonas aeruginosa rsma plays an important role during murine infection by influencing colonization, virulence, persistence, and pulmonary inflammation. Infect Immun 2008;76:632-638. (Pubitemid 351251733)
10. Nielsen KL, Pedersen TM, Udekwu KI, Petersen A, Skov RL, Hansen LH, Hughes D, Frimodt-Moller N: Fitness cost: a bacteriological explanation for the demise of the first international methicillin-resistant Staphylococcus aureus epidemic. J Antimicrob Chemother 2012;67:1325-1332.
11. Komp Lindgren P, Marcusson LL, Sandvang D, Frimodt-Moller N, Hughes D: Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections. Antimicrob Agents Chemother 2005;49:2343-2351. (Pubitemid 40734464)
12. Sander P, Springer B, Prammananan T, Sturmfels A, Kappler M, Pletschette M, Bottger EC: Fitness Cost of Chromosomal Drug Resistance-Conferring Mutations. Antimicrob Agents Chemother 2002;46:1204-1211. (Pubitemid 34415292)
13. Kugelberg E, Lofmark S, Wretlind B, Andersson DI: Reduction of the fitness burden of quinolone resistance in Pseudomonas aeruginosa. J Antimicrob Chemother 2005;55:22-30. (Pubitemid 40192610)
14. Hocquet D, Berthelot P, Roussel-Delvallez M, Favre R, Jeannot K, Bajolet O, Marty N, Grattard F, Mariani-Kurkdjian P, Bingen E, Husson MO, Couetdic G,Plésiat P: Pseudomonas aeruginosa may Accumulate Drug Resistance Mechanisms without Losing Its Ability To Cause Bloodstream Infections. Antimicrob Agents Chemother 2007;51:3531-3536. (Pubitemid 47519340)
15. Kong KF, Jayawardena SR, Indulkar SD, Del Puerto A, Koh CL, Hoiby N, Mathee K: Pseudomonas aeruginosa ampr is a global transcriptional factor that regulates expression of ampc and poxb beta-lactamases, proteases, quorum sensing, and other virulence factors. Antimicrob Agents Chemother 2005;49:4567-4575. (Pubitemid 41552586)
16. Moya B, Juan C, Alberti S, Perez JL, Oliver A: Benefit of having multiple ampd genes for acquiring beta-lactam resistance without losing fitness and virulence in pseudomonas aeruginosa. Antimicrob Agents Chemother 2008;52:3694-3700.
17. Sanchez P, Linares JF, Ruiz-Diez B, Campanario E, Navas A, Baquero F, Martinez JL: Fitness of in vitro selected pseudomonas aeruginosa nalb and nfxb multidrug resistant mutants. J Antimicrob Chemother 2002;50:657-664. (Pubitemid 35331682)
18. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; 19th informational supplement. CLSI document M100-S19. Wayne, PA: CLSI, 2009.
19. Mahenthiralingam E, Campbell ME, Foster J, Lam JS, Speert DP: Random amplified polymorphic DNA typing of pseudomonas aeruginosa isolates recovered from patients with cystic fibrosis. J Clin Microbiol 1996;34:1129-1135. (Pubitemid 26126878)
20. Di Martino P, Gagniere H, Berry H, Bret L: Antibiotic resistance and virulence properties of pseudomonas aeruginosa strains from mechanically ventilated patients with pneumonia in intensive care units: Comparison with imipenem-resistant extra-respiratory tract isolates from uninfected patients. Microbes Infect 2002;4:613-620. (Pubitemid 34607411)
21. Deptula A, Gospodarek E: Reduced expression of virulence factors in multidrug-resistant pseudomonas aeruginosa strains. Arch Microbiol 2010;192:79-84.
22. Kessler E, Israel M, Landshman N, Chechick A, Blumberg S: In vitro inhibition of pseudomonas aeruginosa elastase by metal-chelating peptide derivatives. Infect Immun 1982;38:716-723. (Pubitemid 12002695)
23. Hentzer M, Riedel K, Rasmussen TB, Heydorn A, Andersen JB, Parsek MR, Rice SA, Eberl L, Molin S, Hoiby N, Kjelleberg S, Givskov M: Inhibition of quorum sensing in pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology 2002;148:87-102. (Pubitemid 34083188)
24. Jackson KD, Starkey M, Kremer S, Parsek MR, Wozniak DJ: Identification of psl, a locus encoding a potential exopolysaccharide that is essential for pseudomonas aeruginosa pao1 biofilm formation. J Bacteriol 2004;186:4466-4475. (Pubitemid 38891009)
25. O'Toole GA, Kolter R: Initiation of biofilm formation in pseudomonas fluorescens wcs365 proceeds via multiple, convergent signalling pathways: A genetic analysis. Mol Microbiol 1998;28:449-461. (Pubitemid 28218392)
26. Wang YP, Li L, Shen JZ, Yang FJ, Wu YN: Quinolone-resistance in salmonella is associated with decreased mrna expression of virulence genes inva and avra, growth and intracellular invasion and survival. Vet Microbiol 2009;133:328-334.
27. Lagoumintzis G, Christofidou M, Dimitracopoulos G, Paliogianni F: Pseudomonas aeruginosa slime glycolipoprotein is a potent stimulant of tumor necrosis factor alpha gene expression and activation of transcription activators nuclear factor kappa b and activator protein 1 in human monocytes. Infect Immun 2003;71:4614-4622. (Pubitemid 36919928)
28. Kharazmi A: Interactions of pseudomonas aeruginosa proteases with the cells of the immune system. Antibiot Chemother 1989;42:42-49.
29. Cowell BA, Twining SS, Hobden JA, Kwong MS, Fleiszig SM: Mutation of lasa and lasb reduces pseudomonas aeruginosa invasion of epithelial cells. Microbiology 2003;149:2291-2299. (Pubitemid 37038435)
30. Kessler E, Safrin M, Gustin JK, Ohman DE: Elastase and the LasA protease of Pseudomonas aeruginosa are secreted with their propeptides, J Bio Chem 1998;273:30225-30231. (Pubitemid 28545487)
31. Donlan RM, Costerton JW: Biofilms: Survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 2002;15:167-193. (Pubitemid 34303762)