Pseudomonas aeruginosa slime glycolipoprotein is a potent stimulant of tumor necrosis factor alpha gene expression and activation of transcription activators nuclear factor κB and activator protein 1 in human monocytes

Infection and Immunity

Volumn 71, Issue 8, 2003, Pages 4614-4622

  Lagoumintzis, George ^a   Christofidou, Myrto ^a   Dimitracopoulos, George ^a   Paliogianni, Fotini ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; SLIME GLYCOLIPOPROTEIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN THP 1; CYTOKINE PRODUCTION; GEL MOBILITY SHIFT ASSAY; GENE INDUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; INFLAMMATION; MONOCYTE; NONHUMAN; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RNA ANALYSIS; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; CELL LINE; GENE EXPRESSION; HUMANS; KINETICS; MONOCYTES; NF-KAPPA B; PSEUDOMONAS AERUGINOSA; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; VIRULENCE;

EID: 0042265032     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.8.4614-4622.2003     Document Type: Article

References (50)

1. Anastassiou, E. D., A. C. Mintzas, C. Kounavis, and G. Dimitracopoulos. 1987. Alginate production by clinical nonmucoid Pseudomonas aeruginosa strains. J. Clin. Microbiol. 25:656-659.
2. Arsenis, G., and G. Dimitracopoulos. 1986. Chemical composition of the extracellular slime glycolipoprotein of Pseudomonas aeruginosa and its relation to gentamicin resistance. J. Med. Microbiol. 21:199-202.
3. Banck, G., and A. Forsgren. 1999. Many bacterial species are mitogenic for human blood B lymphocytes. Scand. J. Immunol. 8:347-354.
4. Belcher, R., A. J. Nutten, and C. M. Sambrook. 1954. The determination of glycosamine. Analyst (London) 79:201-208.
5. Berntzen, G., T. H. Flo, A. Medvedev, L. Kilaas, G. Skjak-Braek, A. Sundan, and T. Espevik. 1998. The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles. Clin. Diagn. Lab. Immunol. 5:355-361.
6. Bitter, T., and H. M. Muir. 1962. A modified uronic acid carbazole reaction. Anal. Biochem. 4:330-333.
7. Bodey, G. P., R. Bolivar, V. Fainstein, and L. Jadeja. 1983. Infections caused by Pseudomonas aeruginosa. Rev. Infect. Dis. 5:279-313.
8. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
9. Chen, P. S., T. Y. Toribara, and H. Warner. 1956. Microdetermination of phosphorus. Anal. Chem. 28:1756-1758.
10. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
11. Christofidou, M., N. K. Karamanos, A. C. Mintzas, G. Dimitracopoulos, and E. D. Anastassiou. 1993. Occurrence of a 29 kDa polysaccharide in the slime layer of both smooth and rough strains of Pseudomonas aeruginosa. Int. J. Biochem. 25:313-318.
12. Cusumano, V., M. A. Tufano, G. Mancuso, M. Carbone, F. Rossano, M. T. Fera, F. A. Ciliberti, E. Ruocco, R. A. Merendino, and G. Teti. 1997. Porins of Pseudomonas aeruginosa induce release of tumor necrosis factor alpha and interleukin-6 by human leukocytes. Infect. Immun. 65:1683-1687.
13. Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
14. Dimitracopoulos, G., and P. F. Bartell. 1980. Slime glycolipoproteins and the pathogenicity of various strains of Pseudomonas aeruginosa in experimental infection. Infect. Immun. 30:402-408.
15. Dimitracopoulos, G., J. W. Sensakovic, and P. F. Bartell. 1974. Slime of Pseudomonas aeruginosa: in vivo production. Infect. Immun. 10:152-156.
16. Eaves-Pyles, T., C. Szabo, and A. L. Salzman. 1999. Bacterial invasion is not required for activation of NF-κB in enterocytes. Infect. Immun. 67:800-804.
17. Epelman, S., T. F. Bruno, G. G. Neely, D. E. Woods, and C. H. Mody. 2000. Pseudomonas aeruginosa exoenzyme S induces transcriptional expression of proinflammatory cytokines and chemokines. Infect. Immun. 68:4811-4814.
18. Fraser, I. P., H. Koziel, and R. A. Ezekowitz. 1998. The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity. Semin. Immunol. 10:363-372.
19. Garcia, J., B. Lemercier, S. Roman-Roman, and G. Rawadi. 1998. A Mycoplasma fermentans-derived synthetic lipopeptide induces AP-1 and NF-κB activity and cytokine secretion in macrophages via the activation of mitogen-activated protein kinase pathways. J. Biol. Chem. 273:34391-34398.
20. Giri, D. K., R. T. Mehta, R. G. Kansal, and B. B Aggarwal. 1998. Mycobacterium avium-intracellulare complex activates nuclear transcription factor-κB in different cell types through reactive oxygen intermediates. J. Immunol. 161:4834-4841.
21. Guha, M., W. Bai, J. L. Nadler, and R. Natarajan. 2000. Molecular mechanisms of tumor necrosis factor alpha gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and independent pathways. J. Biol. Chem. 275:17728-17739.
22. Guo, L., K. B. Lim, J. S. Gunn, B. Bainbridge, R. P. Darveau, M. Hackett, and S. I. Miller. 1997. Regulation of lipid A modifications by Salmonella typhimurium virulence genes phoP-phoQ. Science 276:250-253.
23. Hambleton J., S. L Weinstein, L. Lem, and A. L. DeFranco. 1996. Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. Proc. Natl. Acad. Sci. USA 93:2774-2778.
24. Han, J., T. Brown, and B. Beutler. 1990. Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level. J. Exp. Med. 171:465-475.
25. Hauf, N., W. Goebel, F. Fiedler, Z. Sokolovic, and M. Kuhn. 1997. Listeria monocytogenes infection of P388D1 macrophages results in a biphasic NF-κB (RelA/p50) activation induced by lipoteichoic acid and bacterial phospholipases and mediated by IκBα and IκBβ degradation. Proc. Natl. Acad. Sci. USA 94:9394-9399.
26. Jahr, T. G., L. Ryan, A. Sundan, H. S. Lichenstein, G. Skjak-Braek, and T. Espevik. 1997. Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/permeability-increasing factor. Infect. Immun. 65:89-94.
27. Jongeneel, C. V. 1992. The molecules and their emerging role in medicine, p. 539-559. In B Beutler (ed.), Tumor necrosis factors. Raven Press, New York, N.Y.
28. Kuprash, D. V., I. A. Udalova, R. L. Turetskaya, D. Kwiatkowski, N. R. Rice, and S. A. Nedospasov. 1999. Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide. J. Immunol. 162:4045-4052.
29. Lowry, O., N. J. Rosebrough A. L. Farr, and R. J. Randall. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
30. McGinley, M. D., L. O. Nahri, M. J. Kelley, E. Davy, J. Robinson, M. F. Rohde, S. D. Wright, and H. S. Linchenstein. 1995. CD14: physical properties and identification of an exposed site that is protected by lipopolysaccharide. J. Biol. Chem. 270:5213-5218.
31. Orr, T., L. H. Koepp, and P. F. Bartell. 1982. Carbohydrate mediation of the biological activities of the glycolipoprotein of Pseudomonas aeruginosa. J. Gen. Microbiol. 128:2631-2638.
32. Otterlei, M., A. Sundan, G. Skjak-Braek, L. Ryan, O. Smidsrod, and T. Espevik. 1993. Similar mechanisms of action of defined polysaccharides and lipopolysaccharides: characterization of binding and tumor necrosis factor alpha induction. Infect. Immun. 61:1917-1925.
33. Papamichail, M., G. Dimitracopoulos, G. Tsokos, and J. Papavassiliou. 1980. A human lymphocyte mitogen extracted from the extracellular slime layer of Pseudomonas aeruginosa. J. Infect. Dis. 141:686-688.
34. Pier, G. B., W. J. Matthews, Jr., and D. D Eardley. 1983. Immunochemical characterization of the mucoid exopolysaccharide of Pseudomonas aeruginosa. J. Infect. Dis. 147:494-503.
35. Reese, J. F., G. Dimitracopoulos, and P. F. Bartell. 1974. Factors influencing the adsorption of bacteriophage 2 to cells of Pseudomonas aeruginosa. J. Virol. 13:22-27.
36. Rock, F. L., G. Hardiman, J. C. Timans, R. A. Kastelein, and J. F. Bazan. 1998. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA 95:588-593.
37. Sensacovic, J. W., and P. F. Bartell. 1974. The slime of Pseudomonas aeruginosa: biological characterization and possible role in experimental infection. J. Infect. Dis. 129:101-109.
38. Shakhov, A. N., M. A. Collart, P. Vassalli, S. A. Nedospasov, and C. V. Jongeneel. 1990. Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J. Exp. Med. 171:35-47.
39. Spiro, R. G. 1966. Analysis of sugars found in glycoproteins. Methods Enzymol. 8:3-26.
40. Staugas, R. E., D. P. Harvey, A. Ferrante, M. Nandoskar, and A. C. Allison. 1992. Induction of tumor necrosis factor (TNF) and interleukin-1 (IL-1) by Pseudomonas aeruginosa and exotoxin A-induced suppression of lymphoproliferation and TNF, lymphotoxin, gamma interferon, and IL-1 production in human leukocytes. Infect. Immun. 60:3162-3168.
41. Steer, J. H., K. M. Kroeger, L. J. Abraham, and D. A. Joyce. 2000. Glucocorticoids suppress tumor necrosis factor alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun activating transcription factor-2 binding sites in the promoter. J. Biol. Chem. 275:18432-18440.
42. Tracey, K. J., and A. Cerami. 1994. Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Annu. Rev. Med. 45:491-503.
43. Trede N. S., A. V. Tsytsykova, T. Chatila, A. E. Goldfeld, and R. S Geha. 1995. Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B. J. Immunol. 155:902-908.
44. Tsai, E. Y., J. V. Falvo, A. V. Tsytsycova, A. K. Barczak, A. M. Reimold, L. H. Glimcher, M. J. Fenton, D. Gordon, I. F. Dunn, and A. E. Goldfeld. 2000. A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Mol. Cell. Biol. 16:6084-6094.
45. Tsuchiya, S., Y. Kobayashi, Y. Goto, H. Okumura, S. Nakae, T. Konno, and K. Tada. 1982. Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester. Cancer Res. 42:1530-1536.
46. Ulmer, A. J., J. Pryjma, Z. Tarnok, M. Ernst, and H. D. Flad. 1990. Inhibitory and stimulatory effects of Pseudomonas aeruginosa pyocyanine on human T and B lymphocytes and human monocytes. Infect. Immun. 58:808-815.
47. Vallejo J. G., P. Knuefermann, D. L Mann, and N. Sivasubramanian. 2000. Group B Streptococcus induces TNF-alpha gene expression and activation of the transcription factors NF-kappa B and activator protein-1 in human cord blood monocytes. J. Immunol. 165:419-425.
48. Varey, A. M., A. Cooke, G. Dimitrocopoulos, and M. Papamichail. 1984. Mitogenic effects of glycolipoprotein extract from Pseudomonas aeruginosa. Clin. Exp. Immunol. 56:431-437.
49. Yao, J., N. Mackman, T. S. Edgington, and S. T. Fan. 1997. Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors. J. Biol. Chem. 272:17795-17801.
50. Zughaier, S. M., H. C. Ryley, and S. K Jackson. 1999. Lipopolysaccharide (LPS) from Burkholderia cepacia is more active than LPS from Pseudomonas aeruginosa and Stenotrophomonas maltophilia in stimulating tumor necrosis factor alpha from human monocytes. Infect. Immun. 67:1505-1507.