-
1
-
-
77957765210
-
Innate immunity in systemic lupus erythematosus: sensing endogenous nucleic acids
-
Kontaki E, Boumpas DT, (2010) Innate immunity in systemic lupus erythematosus: sensing endogenous nucleic acids. J Autoimmun 35: 206-211.
-
(2010)
J Autoimmun
, vol.35
, pp. 206-211
-
-
Kontaki, E.1
Boumpas, D.T.2
-
2
-
-
84861235405
-
Emerging therapies for systemic lupus erythematosus-focus on targeting interferon-alpha
-
Lichtman EI, Helfgott SM, Kriegel MA, (2012) Emerging therapies for systemic lupus erythematosus-focus on targeting interferon-alpha. Clin Immunol 143: 210-221.
-
(2012)
Clin Immunol
, vol.143
, pp. 210-221
-
-
Lichtman, E.I.1
Helfgott, S.M.2
Kriegel, M.A.3
-
3
-
-
78649830454
-
Genetic susceptibility to systemic lupus erythematosus in the genomic era
-
Deng Y, Tsao BP, (2010) Genetic susceptibility to systemic lupus erythematosus in the genomic era. Nat Rev Rheumatol 6: 683-692.
-
(2010)
Nat Rev Rheumatol
, vol.6
, pp. 683-692
-
-
Deng, Y.1
Tsao, B.P.2
-
4
-
-
84867745567
-
The genetics of type I interferon in systemic lupus erythematosus
-
Bronson PG, Chaivorapol C, Ortmann W, Behrens TW, Graham RR, (2012) The genetics of type I interferon in systemic lupus erythematosus. Curr Opin Immunol [Epub ahead of print].
-
(2012)
Curr Opin Immunol
-
-
Bronson, P.G.1
Chaivorapol, C.2
Ortmann, W.3
Behrens, T.W.4
Graham, R.R.5
-
5
-
-
77957673544
-
Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus
-
Shen N, Fu Q, Deng Y, Qian X, Zhao J, et al. (2010) Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus. Proc Natl Acad Sci U S A 107: 15838-15843.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15838-15843
-
-
Shen, N.1
Fu, Q.2
Deng, Y.3
Qian, X.4
Zhao, J.5
-
7
-
-
33847665108
-
Human polymorphism at microRNAs and microRNA target sites
-
Saunders MA, Liang H, Li WH, (2007) Human polymorphism at microRNAs and microRNA target sites. Proc Natl Acad Sci U S A 104: 3300-3305.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3300-3305
-
-
Saunders, M.A.1
Liang, H.2
Li, W.H.3
-
8
-
-
84863116007
-
miRNA-mediated relationships between Cis-SNP genotypes and transcript intensities in lymphocyte cell lines
-
doi:10.1371/journal.pone.0031429
-
Zhang W, Edwards A, Zhu D, Flemington EK, Deininger P, et al. (2012) miRNA-mediated relationships between Cis-SNP genotypes and transcript intensities in lymphocyte cell lines. PLoS ONE 7: e31429 doi:10.1371/journal.pone.0031429.
-
(2012)
PLoS ONE
, vol.7
-
-
Zhang, W.1
Edwards, A.2
Zhu, D.3
Flemington, E.K.4
Deininger, P.5
-
9
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Pisitkun P, Deane JD, Diffilipantonio MJ, Tarasenko T, Satterthwaite AB, et al. (2006) Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 312: 1669-1672.
-
(2006)
Science
, vol.312
, pp. 1669-1672
-
-
Pisitkun, P.1
Deane, J.D.2
Diffilipantonio, M.J.3
Tarasenko, T.4
Satterthwaite, A.B.5
-
10
-
-
33745617886
-
A TLR7 translocation accelerates systemic autoimmunity in murine lupus
-
Subramanian S, Tus K, Li QZ, Wang A, Tian XH, et al. (2006) A TLR7 translocation accelerates systemic autoimmunity in murine lupus. Proc Natl Acad Sci USA 103: 9970-9975.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9970-9975
-
-
Subramanian, S.1
Tus, K.2
Li, Q.Z.3
Wang, A.4
Tian, X.H.5
-
11
-
-
50549086761
-
Yaa autoimmune phenotypes are conferred by overexpression of TLR7
-
Fairhurst AM, Hwang SH, Wang A, Tian XH, Boudreaux C, et al. (2008) Yaa autoimmune phenotypes are conferred by overexpression of TLR7. Eur J Immunol 38: 1971-1978.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1971-1978
-
-
Fairhurst, A.M.1
Hwang, S.H.2
Wang, A.3
Tian, X.H.4
Boudreaux, C.5
-
12
-
-
36048962438
-
Control of Toll-like Receptor 7 Expression Is Essential to Restrict Autoimmunity and Dendritic Cell Proliferation
-
Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, et al. (2007) Control of Toll-like Receptor 7 Expression Is Essential to Restrict Autoimmunity and Dendritic Cell Proliferation. Immunity 27: 801-810.
-
(2007)
Immunity
, vol.27
, pp. 801-810
-
-
Deane, J.A.1
Pisitkun, P.2
Barrett, R.S.3
Feigenbaum, L.4
Town, T.5
-
13
-
-
32444451688
-
The type I interferon system in systemic lupus erythematosus
-
Ronnblom L, Eloranta ML, Alm GV, (2006) The type I interferon system in systemic lupus erythematosus. Arthritis Rheum 54: 408-420.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 408-420
-
-
Ronnblom, L.1
Eloranta, M.L.2
Alm, G.V.3
-
14
-
-
43349094856
-
Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
-
Komatsuda A, Wakui H, Iwamoto K, Ozawa M, Togashi M, et al. (2008) Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Clin Exp Immunol 152: 482-487.
-
(2008)
Clin Exp Immunol
, vol.152
, pp. 482-487
-
-
Komatsuda, A.1
Wakui, H.2
Iwamoto, K.3
Ozawa, M.4
Togashi, M.5
-
15
-
-
84860255736
-
Expression of Toll-like receptors and their detection of nuclear self-antigen leading to immune activation in JSLE
-
Midgley A, Thorbinson C, Beresford MW, (2012) Expression of Toll-like receptors and their detection of nuclear self-antigen leading to immune activation in JSLE. Rheumatology (Oxford) 51: 824-832.
-
(2012)
Rheumatology (Oxford)
, vol.51
, pp. 824-832
-
-
Midgley, A.1
Thorbinson, C.2
Beresford, M.W.3
-
16
-
-
77957282676
-
Association of TLR7 copy number variation with susceptibility to childhood-onset systemic lupus erythematosus in Mexican population
-
Garcia-Ortiz H, Velazquez-Cruz R, Espinosa-Rosales F, Jimenez-Morales S, Baca V, et al. (2010) Association of TLR7 copy number variation with susceptibility to childhood-onset systemic lupus erythematosus in Mexican population. Ann Rheum Dis 69: 1861-1865.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1861-1865
-
-
Garcia-Ortiz, H.1
Velazquez-Cruz, R.2
Espinosa-Rosales, F.3
Jimenez-Morales, S.4
Baca, V.5
-
17
-
-
77950461601
-
Origins and functional impact of copy number variation in the human genome
-
Conrad DF, Pinto D, Redon R, Feuk L, Gokcumen O, et al. (2010) Origins and functional impact of copy number variation in the human genome. Nature 464: 704-712.
-
(2010)
Nature
, vol.464
, pp. 704-712
-
-
Conrad, D.F.1
Pinto, D.2
Redon, R.3
Feuk, L.4
Gokcumen, O.5
-
18
-
-
77951719393
-
Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing
-
Park H, Kim JI, Ju YS, Gokcumen O, Mills RE, et al. (2010) Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing. Nat Genet 42: 400-405.
-
(2010)
Nat Genet
, vol.42
, pp. 400-405
-
-
Park, H.1
Kim, J.I.2
Ju, Y.S.3
Gokcumen, O.4
Mills, R.E.5
-
19
-
-
40049108936
-
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
-
Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, et al. (2008) Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 358: 900-909.
-
(2008)
N Engl J Med
, vol.358
, pp. 900-909
-
-
Hom, G.1
Graham, R.R.2
Modrek, B.3
Taylor, K.E.4
Ortmann, W.5
-
20
-
-
38649125210
-
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
-
Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, et al. (2008) Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 40: 204-210.
-
(2008)
Nat Genet
, vol.40
, pp. 204-210
-
-
Harley, J.B.1
Alarcon-Riquelme, M.E.2
Criswell, L.A.3
Jacob, C.O.4
Kimberly, R.P.5
-
21
-
-
38649138296
-
Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus
-
Kozyrev SV, Abelson AK, Wojcik J, Zaghlool A, Linga Reddy MV, et al. (2008) Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Nat Genet 40: 211-216.
-
(2008)
Nat Genet
, vol.40
, pp. 211-216
-
-
Kozyrev, S.V.1
Abelson, A.K.2
Wojcik, J.3
Zaghlool, A.4
Linga Reddy, M.V.5
-
22
-
-
50449111452
-
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
-
Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, et al. (2008) Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 40: 1059-1061.
-
(2008)
Nat Genet
, vol.40
, pp. 1059-1061
-
-
Graham, R.R.1
Cotsapas, C.2
Davies, L.3
Hackett, R.4
Lessard, C.J.5
-
23
-
-
70350629871
-
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
-
Han JW, Zheng HF, Cui Y, Sun LD, Ye DQ, et al. (2009) Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet 41: 1234-1237.
-
(2009)
Nat Genet
, vol.41
, pp. 1234-1237
-
-
Han, J.W.1
Zheng, H.F.2
Cui, Y.3
Sun, L.D.4
Ye, D.Q.5
-
24
-
-
77649206245
-
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus
-
doi:10.1371/journal.pgen.1000841
-
Yang W, Shen N, Ye DQ, Liu Q, Zhang Y, et al. (2010) Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus. PLoS Genet 6: e1000841 doi:10.1371/journal.pgen.1000841.
-
(2010)
PLoS Genet
, vol.6
-
-
Yang, W.1
Shen, N.2
Ye, D.Q.3
Liu, Q.4
Zhang, Y.5
-
25
-
-
84857487791
-
A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese
-
doi:10.1371/journal.pgen.1002455
-
Okada Y, Shimane K, Kochi Y, Tahira T, Suzuki A, et al. (2012) A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. PLoS Genet 8: e1002455 doi:10.1371/journal.pgen.1002455.
-
(2012)
PLoS Genet
, vol.8
-
-
Okada, Y.1
Shimane, K.2
Kochi, Y.3
Tahira, T.4
Suzuki, A.5
-
26
-
-
79952461669
-
TLR7 single-nucleotide polymorphisms in the 3′ untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study
-
Kawasaki A, Furukawa H, Kondo Y, Ito S, Hayashi T, et al. (2011) TLR7 single-nucleotide polymorphisms in the 3′ untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study. Arthritis Res Ther 13: R41.
-
(2011)
Arthritis Res Ther
, vol.13
-
-
Kawasaki, A.1
Furukawa, H.2
Kondo, Y.3
Ito, S.4
Hayashi, T.5
-
27
-
-
84856761468
-
TLR7/8/9 polymorphisms and their associations in systemic lupus erythematosus patients from southern Brazil
-
dos Santos BP, Valverde JV, Rohr P, Monticielo OA, Brenol JC, et al. (2012) TLR7/8/9 polymorphisms and their associations in systemic lupus erythematosus patients from southern Brazil. Lupus 21: 302-309.
-
(2012)
Lupus
, vol.21
, pp. 302-309
-
-
dos Santos, B.P.1
Valverde, J.V.2
Rohr, P.3
Monticielo, O.A.4
Brenol, J.C.5
-
28
-
-
55449113946
-
Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis
-
doi:10.1371/journal.pgen.1000218
-
Davila S, Hibberd ML, Hari Dass R, Wong HE, Sahiratmadja E, et al. (2008) Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis. PLoS Genet 4: e1000218 doi:10.1371/journal.pgen.1000218.
-
(2008)
PLoS Genet
, vol.4
-
-
Davila, S.1
Hibberd, M.L.2
Hari Dass, R.3
Wong, H.E.4
Sahiratmadja, E.5
-
29
-
-
50949083798
-
A functional toll-like receptor 8 variant is associated with HIV disease restriction
-
Oh DY, Taube S, Hamouda O, Kucherer C, Poggensee G, et al. (2008) A functional toll-like receptor 8 variant is associated with HIV disease restriction. J Infect Dis 198: 701-709.
-
(2008)
J Infect Dis
, vol.198
, pp. 701-709
-
-
Oh, D.Y.1
Taube, S.2
Hamouda, O.3
Kucherer, C.4
Poggensee, G.5
-
30
-
-
60349092402
-
Mapping complex disease traits with global gene expression
-
Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M, (2009) Mapping complex disease traits with global gene expression. Nat Rev Genet 10: 184-194.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 184-194
-
-
Cookson, W.1
Liang, L.2
Abecasis, G.3
Moffatt, M.4
Lathrop, M.5
-
31
-
-
84860596557
-
Patterns of cis regulatory variation in diverse human populations
-
doi:10.1371/journal.pgen.1002639
-
Stranger BE, Montgomery SB, Dimas AS, Parts L, Stegle O, et al. (2012) Patterns of cis regulatory variation in diverse human populations. PLoS Genet 8: e1002639 doi:10.1371/journal.pgen.1002639.
-
(2012)
PLoS Genet
, vol.8
-
-
Stranger, B.E.1
Montgomery, S.B.2
Dimas, A.S.3
Parts, L.4
Stegle, O.5
-
32
-
-
79952186298
-
MicroRNAs: the fine-tuners of Toll-like receptor signalling
-
O'Neill LA, Sheedy FJ, McCoy CE, (2011) MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nat Rev Immunol 11: 163-175.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 163-175
-
-
O'Neill, L.A.1
Sheedy, F.J.2
McCoy, C.E.3
-
33
-
-
84858000196
-
MicroRNAs in inflammation and immune responses
-
Contreras J, Rao DS, (2012) MicroRNAs in inflammation and immune responses. Leukemia 26: 404-413.
-
(2012)
Leukemia
, vol.26
, pp. 404-413
-
-
Contreras, J.1
Rao, D.S.2
-
34
-
-
69249085731
-
Modulation of TLR2 protein expression by miR-105 in human oral keratinocytes
-
Benakanakere MR, Li Q, Eskan MA, Singh AV, Zhao J, et al. (2009) Modulation of TLR2 protein expression by miR-105 in human oral keratinocytes. J Biol Chem 284: 23107-23115.
-
(2009)
J Biol Chem
, vol.284
, pp. 23107-23115
-
-
Benakanakere, M.R.1
Li, Q.2
Eskan, M.A.3
Singh, A.V.4
Zhao, J.5
-
35
-
-
35348929402
-
A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection
-
Chen XM, Splinter PL, O'Hara SP, LaRusso NF, (2007) A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection. J Biol Chem 282: 28929-28938.
-
(2007)
J Biol Chem
, vol.282
, pp. 28929-28938
-
-
Chen, X.M.1
Splinter, P.L.2
O'Hara, S.P.3
LaRusso, N.F.4
-
36
-
-
77950456855
-
Characterization of the Melanoma miRNAome by Deep Sequencing
-
doi:10.1371/journal.pone.0009685
-
Stark MS, Tyagi S, Nancarrow DJ, Boyle GM, Cook AL, et al. (2010) Characterization of the Melanoma miRNAome by Deep Sequencing. PLoS ONE 5: e9685 doi:10.1371/journal.pone.0009685.
-
(2010)
PLoS ONE
, vol.5
-
-
Stark, M.S.1
Tyagi, S.2
Nancarrow, D.J.3
Boyle, G.M.4
Cook, A.L.5
-
37
-
-
84861577379
-
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration
-
Lehmann SM, Kruger C, Park B, Derkow K, Rosenberger K, et al. (2012) An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat Neurosci 15: 827-835.
-
(2012)
Nat Neurosci
, vol.15
, pp. 827-835
-
-
Lehmann, S.M.1
Kruger, C.2
Park, B.3
Derkow, K.4
Rosenberger, K.5
-
38
-
-
84864503916
-
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
-
Fabbri M, Paone A, Calore F, Galli R, Gaudio E, et al. (2012) MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response. Proc Natl Acad Sci U S A 109: E2110-2116.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
-
-
Fabbri, M.1
Paone, A.2
Calore, F.3
Galli, R.4
Gaudio, E.5
-
39
-
-
0031229830
-
Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
-
Hochberg MC, (1997) Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 40: 1725.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1725
-
-
Hochberg, M.C.1
-
40
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nature Genetics 38: 904-909.
-
(2006)
Nature Genetics
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
-
41
-
-
0037648359
-
Control of confounding of genetic associations in stratified populations
-
Hoggart CJ, Parra EJ, Shriver MD, Bonilla C, Kittles RA, et al. (2003) Control of confounding of genetic associations in stratified populations. Am J Hum Genet 72: 1492-1504.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1492-1504
-
-
Hoggart, C.J.1
Parra, E.J.2
Shriver, M.D.3
Bonilla, C.4
Kittles, R.A.5
-
42
-
-
78650862201
-
Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study
-
Lessard CJ, Adrianto I, Kelly JA, Kaufman KM, Grundahl KM, et al. (2011) Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet 88: 83-91.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 83-91
-
-
Lessard, C.J.1
Adrianto, I.2
Kelly, J.A.3
Kaufman, K.M.4
Grundahl, K.M.5
-
43
-
-
67651222400
-
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
doi:10.1371/journal.pgen.1000529
-
Howie BN, Donnelly P, Marchini J, (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet 5: e1000529 doi:10.1371/journal.pgen.1000529.
-
(2009)
PLoS Genet
, vol.5
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
44
-
-
0024151602
-
The HL60 cell line: a model system for studying human myeloid cell differentiation
-
Birnie GD, (1988) The HL60 cell line: a model system for studying human myeloid cell differentiation. Br J Cancer Suppl 9: pp. 41-45.
-
(1988)
Br J Cancer
, Issue.SUPPL. 9
, pp. 41-45
-
-
Birnie, G.D.1
|