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Volumn 41, Issue 3, 2013, Pages 247-261

Meta-analysis of second-trimester markers for trisomy 21

Author keywords

Down syndrome; pyramid of care; second trimester screening; sonographic markers; trisomy 21

Indexed keywords

DOWN SYNDROME; ECHOGRAPHY; FEMALE; FETUS ECHOGRAPHY; HUMAN; META ANALYSIS; METHODOLOGY; PREGNANCY; PRENATAL DIAGNOSIS; REVIEW; RISK FACTOR; SECOND TRIMESTER PREGNANCY; SENSITIVITY AND SPECIFICITY;

EID: 84874732295     PISSN: 09607692     EISSN: 14690705     Source Type: Journal    
DOI: 10.1002/uog.12364     Document Type: Review
Times cited : (209)

References (61)
  • 1
    • 0028822791 scopus 로고
    • Normal nuchal thickness in the midtrimester indicates reduced risk of Down syndrome in pregnancies with abnormal triple-screen results
    • Bahado-Singh RO, Goldstein I, Uerpairojkit B, Copel JA, Mahoney MJ, Baumgarten A,. Normal nuchal thickness in the midtrimester indicates reduced risk of Down syndrome in pregnancies with abnormal triple-screen results. Am J Obstet Gynecol 1995; 173: 1106-1110.
    • (1995) Am J Obstet Gynecol , vol.173 , pp. 1106-1110
    • Bahado-Singh, R.O.1    Goldstein, I.2    Uerpairojkit, B.3    Copel, J.A.4    Mahoney, M.J.5    Baumgarten, A.6
  • 2
    • 0028817636 scopus 로고
    • The use of color Doppler ultrasound to identify fetuses at increased risk for trisomy 21: An alternative for high-risk patients who decline genetic amniocentesis
    • DeVore GR, Alfi O,. The use of color Doppler ultrasound to identify fetuses at increased risk for trisomy 21: an alternative for high-risk patients who decline genetic amniocentesis. Obstet Gynecol 1995; 85: 378-386.
    • (1995) Obstet Gynecol , vol.85 , pp. 378-386
    • Devore, G.R.1    Alfi, O.2
  • 3
    • 0028859291 scopus 로고
    • Sonographic measurement of nuchal skinfold thickness for detection of Down syndrome in the second-trimester fetus: A multicenter prospective study. the AFDPHE Study Group. Association Française pour le Dépistage et la Prévention des Handicaps de l'Enfant
    • Grandjean H, Sarramon MF,. Sonographic measurement of nuchal skinfold thickness for detection of Down syndrome in the second-trimester fetus: a multicenter prospective study. The AFDPHE Study Group. Association Française pour le Dépistage et la Prévention des Handicaps de l'Enfant. Obstet Gynecol 1995; 85: 103-106.
    • (1995) Obstet Gynecol , vol.85 , pp. 103-106
    • Grandjean, H.1    Sarramon, M.F.2
  • 4
    • 0029116509 scopus 로고
    • Femur/foot length ratio for detection of Down syndrome: Results of a multicenter prospective study. the Association Française pour le Dépistage et la Prévention des Handicaps de l'Enfant Study Group
    • Grandjean H, Sarramon MF,. Femur/foot length ratio for detection of Down syndrome: results of a multicenter prospective study. The Association Française pour le Dépistage et la Prévention des Handicaps de l'Enfant Study Group. Am J Obstet Gynecol 1995; 173: 16-19.
    • (1995) Am J Obstet Gynecol , vol.173 , pp. 16-19
    • Grandjean, H.1    Sarramon, M.F.2
  • 5
    • 0028822788 scopus 로고
    • Role of prenatal ultrasonography in women with positive screen for Down syndrome on the basis of maternal serum markers
    • Nyberg DA, Luthy DA, Cheng EY, Sheley RC, Resta RG, Williams MA,. Role of prenatal ultrasonography in women with positive screen for Down syndrome on the basis of maternal serum markers. Am J Obstet Gynecol 1995; 173: 1030-1035.
    • (1995) Am J Obstet Gynecol , vol.173 , pp. 1030-1035
    • Nyberg, D.A.1    Luthy, D.A.2    Cheng, E.Y.3    Sheley, R.C.4    Resta, R.G.5    Williams, M.A.6
  • 6
    • 0029950690 scopus 로고    scopus 로고
    • The use of second-trimester genetic sonogram in guiding clinical management of patients at increased risk for fetal trisomy 21
    • Vintzileos AM, Campbell WA, Rodis JF, Guzman ER, Smulian JC, Knuppel RA,. The use of second-trimester genetic sonogram in guiding clinical management of patients at increased risk for fetal trisomy 21. Obstet Gynecol 1996; 87: 948-952.
    • (1996) Obstet Gynecol , vol.87 , pp. 948-952
    • Vintzileos, A.M.1    Campbell, W.A.2    Rodis, J.F.3    Guzman, E.R.4    Smulian, J.C.5    Knuppel, R.A.6
  • 8
    • 0031967934 scopus 로고    scopus 로고
    • Subtle ultrasonographic anomalies: Do they improve the Down syndrome detection rate?
    • Deren O, Mahoney MJ, Copel JA, Bahado-Singh RO,. Subtle ultrasonographic anomalies: do they improve the Down syndrome detection rate? Am J Obstet Gynecol 1998; 178: 441-445.
    • (1998) Am J Obstet Gynecol , vol.178 , pp. 441-445
    • Deren, O.1    Mahoney, M.J.2    Copel, J.A.3    Bahado-Singh, R.O.4
  • 9
    • 0031945877 scopus 로고    scopus 로고
    • Significance of fetal intracardiac echogenic foci in relation to trisomy 21: A prospective sonographic study of high-risk pregnant women
    • Manning JE, Ragavendra N, Sayre J, Laifer-Narin SL, Melany ML, Grant EG, Crandall BF,. Significance of fetal intracardiac echogenic foci in relation to trisomy 21: a prospective sonographic study of high-risk pregnant women. AJR Am J Roentgenol 1998; 170: 1083-1084.
    • (1998) AJR Am J Roentgenol , vol.170 , pp. 1083-1084
    • Manning, J.E.1    Ragavendra, N.2    Sayre, J.3    Laifer-Narin, S.L.4    Melany, M.L.5    Grant, E.G.6    Crandall, B.F.7
  • 10
    • 0032717179 scopus 로고    scopus 로고
    • Utility of minor ultrasonographic markers in the prediction of abnormal fetal karyotype at a prenatal diagnostic center
    • Sohl BD, Scioscia AL, Budorick NE, Moore TR,. Utility of minor ultrasonographic markers in the prediction of abnormal fetal karyotype at a prenatal diagnostic center. Am J Obstet Gynecol 1999; 181: 898-903.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 898-903
    • Sohl, B.D.1    Scioscia, A.L.2    Budorick, N.E.3    Moore, T.R.4
  • 13
    • 0033779423 scopus 로고    scopus 로고
    • Efficacy of community-based second trimester genetic ultrasonography in detecting the chromosomally abnormal fetus
    • Wax JR, Guilbert J, Mather J, Chen C, Royer D, Steinfeld JD, Ingardia CJ,. Efficacy of community-based second trimester genetic ultrasonography in detecting the chromosomally abnormal fetus. J Ultrasound Med 2000; 19: 689-694.
    • (2000) J Ultrasound Med , vol.19 , pp. 689-694
    • Wax, J.R.1    Guilbert, J.2    Mather, J.3    Chen, C.4    Royer, D.5    Steinfeld, J.D.6    Ingardia, C.J.7
  • 15
    • 0034789740 scopus 로고    scopus 로고
    • Isolated sonographic markers for detection of fetal Down syndrome in the second trimester of pregnancy
    • Nyberg DA, Souter VL, El-Bastawissi A, Young S, Luthhardt F, Luthy DA,. Isolated sonographic markers for detection of fetal Down syndrome in the second trimester of pregnancy. J Ultrasound Med 2001; 20: 1053-1063.
    • (2001) J Ultrasound Med , vol.20 , pp. 1053-1063
    • Nyberg, D.A.1    Souter, V.L.2    El-Bastawissi, A.3    Young, S.4    Luthhardt, F.5    Luthy, D.A.6
  • 16
    • 0034880507 scopus 로고    scopus 로고
    • Isolated echogenic foci in the fetal heart: Do they increase the risk of trisomy 21 in a population previously screened by nuchal translucency?
    • Prefumo F, Presti F, Mavrides E, Sanusi AF, Bland JM, Campbell S, Carvalho JS,. Isolated echogenic foci in the fetal heart: do they increase the risk of trisomy 21 in a population previously screened by nuchal translucency? Ultrasound Obstet Gynecol 2001; 18: 126-130.
    • (2001) Ultrasound Obstet Gynecol , vol.18 , pp. 126-130
    • Prefumo, F.1    Presti, F.2    Mavrides, E.3    Sanusi, A.F.4    Bland, J.M.5    Campbell, S.6    Carvalho, J.S.7
  • 17
    • 0035704652 scopus 로고    scopus 로고
    • Minor sonographic signs of trisomy 21 at 15-20 weeks' gestation in fetuses born without malformations: A prospective study
    • Viora E, Errante G, Bastonero S, Sciarrone A, Campogrande M,. Minor sonographic signs of trisomy 21 at 15-20 weeks' gestation in fetuses born without malformations: a prospective study. Prenat Diagn 2001; 21: 1163-1166.
    • (2001) Prenat Diagn , vol.21 , pp. 1163-1166
    • Viora, E.1    Errante, G.2    Bastonero, S.3    Sciarrone, A.4    Campogrande, M.5
  • 19
    • 0036898671 scopus 로고    scopus 로고
    • Fetal nose bone length: A marker for Down syndrome in the second trimester
    • Bromley B, Lieberman E, Shipp TD, Benacerraf BR,. Fetal nose bone length: a marker for Down syndrome in the second trimester. J Ultrasound Med 2002; 21: 1387-1394.
    • (2002) J Ultrasound Med , vol.21 , pp. 1387-1394
    • Bromley, B.1    Lieberman, E.2    Shipp, T.D.3    Benacerraf, B.R.4
  • 20
    • 0036789475 scopus 로고    scopus 로고
    • The genetic sonogram: A method of risk assessment for Down syndrome in the second trimester
    • Bromley B, Lieberman E, Shipp TD, Benacerraf BR,. The genetic sonogram: a method of risk assessment for Down syndrome in the second trimester. J Ultrasound Med 2002; 21: 1087-1096.
    • (2002) J Ultrasound Med , vol.21 , pp. 1087-1096
    • Bromley, B.1    Lieberman, E.2    Shipp, T.D.3    Benacerraf, B.R.4
  • 22
  • 24
    • 0038404607 scopus 로고    scopus 로고
    • Absent nasal bone in the prenatal detection of fetuses with trisomy 21 in a high-risk population
    • Vintzileos A, Walters C, Yeo L,. Absent nasal bone in the prenatal detection of fetuses with trisomy 21 in a high-risk population. Obstet Gynecol 2003; 101: 905-908.
    • (2003) Obstet Gynecol , vol.101 , pp. 905-908
    • Vintzileos, A.1    Walters, C.2    Yeo, L.3
  • 25
    • 2442581378 scopus 로고    scopus 로고
    • An isolated echogenic heart focus is not an indication for amniocentesis in 12,672 unselected patients
    • Coco C, Jeanty P, Jeanty C,. An isolated echogenic heart focus is not an indication for amniocentesis in 12,672 unselected patients. J Ultrasound Med 2004; 23: 489-496.
    • (2004) J Ultrasound Med , vol.23 , pp. 489-496
    • Coco, C.1    Jeanty, P.2    Jeanty, C.3
  • 26
    • 4644359218 scopus 로고    scopus 로고
    • Fetal nasal bone length in euploid and aneuploid fetuses between 11 and 20 weeks' gestation: A prospective study
    • Cusick W, Provenzano J, Sullivan CA, Gallousis FM, Rodis JF,. Fetal nasal bone length in euploid and aneuploid fetuses between 11 and 20 weeks' gestation: a prospective study. J Ultrasound Med 2004; 23: 1327-1333.
    • (2004) J Ultrasound Med , vol.23 , pp. 1327-1333
    • Cusick, W.1    Provenzano, J.2    Sullivan, C.A.3    Gallousis, F.M.4    Rodis, J.F.5
  • 27
    • 1242269812 scopus 로고    scopus 로고
    • Ultrasonographic measurement of fetal nasal bone in a low-risk population at 19-22 gestational weeks
    • Gámez F, Ferreiro P, Salmeán JM,. Ultrasonographic measurement of fetal nasal bone in a low-risk population at 19-22 gestational weeks. Ultrasound Obstet Gynecol 2004; 23: 152-153.
    • (2004) Ultrasound Obstet Gynecol , vol.23 , pp. 152-153
    • Gámez, F.1    Ferreiro, P.2    Salmeán, J.M.3
  • 29
    • 24344455177 scopus 로고    scopus 로고
    • Isolated fetal pyelectasis and chromosomal abnormalities
    • Coco C, Jeanty P,. Isolated fetal pyelectasis and chromosomal abnormalities. Am J Obstet Gynecol 2005; 193: 732-738.
    • (2005) Am J Obstet Gynecol , vol.193 , pp. 732-738
    • Coco, C.1    Jeanty, P.2
  • 30
    • 12844255048 scopus 로고    scopus 로고
    • Mid trimester sonographic findings for the prediction of Down syndrome in a sonographically screened population
    • Schluter PJ, Pritchard G,. Mid trimester sonographic findings for the prediction of Down syndrome in a sonographically screened population. Am J Obstet Gynecol 2005; 192: 10-16.
    • (2005) Am J Obstet Gynecol , vol.192 , pp. 10-16
    • Schluter, P.J.1    Pritchard, G.2
  • 31
    • 19544371023 scopus 로고    scopus 로고
    • Second-trimester biparietal diameter/nasal bone length ratio is an independent predictor of trisomy 21
    • Tran LT, Carr DB, Mitsumori LM, Uhrich SB, Shields LE,. Second-trimester biparietal diameter/nasal bone length ratio is an independent predictor of trisomy 21. J Ultrasound Med 2005; 24: 805-810.
    • (2005) J Ultrasound Med , vol.24 , pp. 805-810
    • Tran, L.T.1    Carr, D.B.2    Mitsumori, L.M.3    Uhrich, S.B.4    Shields, L.E.5
  • 33
    • 33646046806 scopus 로고    scopus 로고
    • Evaluating the efficiency of using second-trimester nasal bone hypoplasia as a single or a combined marker for fetal aneuploidy
    • Odibo AO, Sehdev HM, Sproat L, Parra C, Odibo L, Dunn L, Macones GA,. Evaluating the efficiency of using second-trimester nasal bone hypoplasia as a single or a combined marker for fetal aneuploidy. J Ultrasound Med 2006; 25: 437-441.
    • (2006) J Ultrasound Med , vol.25 , pp. 437-441
    • Odibo, A.O.1    Sehdev, H.M.2    Sproat, L.3    Parra, C.4    Odibo, L.5    Dunn, L.6    MacOnes, G.A.7
  • 34
  • 35
    • 33846674238 scopus 로고    scopus 로고
    • Absent or shortened nasal bone length and the detection of Down Syndrome in second-trimester fetuses
    • Gianferrari EA, Benn PA, Dries L, Brault K, Egan JF, Zelop CM,. Absent or shortened nasal bone length and the detection of Down Syndrome in second-trimester fetuses. Obstet Gynecol 2007; 109: 371-375.
    • (2007) Obstet Gynecol , vol.109 , pp. 371-375
    • Gianferrari, E.A.1    Benn, P.A.2    Dries, L.3    Brault, K.4    Egan, J.F.5    Zelop, C.M.6
  • 37
    • 34347209394 scopus 로고    scopus 로고
    • Second trimester prenatal ultrasound for the detection of pregnancies at increased risk of Down syndrome
    • Smith-Bindman R, Chu P, Goldberg JD,. Second trimester prenatal ultrasound for the detection of pregnancies at increased risk of Down syndrome. Prenat Diagn 2007; 27: 535-544.
    • (2007) Prenat Diagn , vol.27 , pp. 535-544
    • Smith-Bindman, R.1    Chu, P.2    Goldberg, J.D.3
  • 38
    • 34247551800 scopus 로고    scopus 로고
    • Ultrasound findings after screening for Down syndrome using the integrated test
    • Weisz B, Pandya PP, David AL, Huttly W, Jones P, Rodeck CH,. Ultrasound findings after screening for Down syndrome using the integrated test. Obstet Gynecol 2007; 109: 1046-1052.
    • (2007) Obstet Gynecol , vol.109 , pp. 1046-1052
    • Weisz, B.1    Pandya, P.P.2    David, A.L.3    Huttly, W.4    Jones, P.5    Rodeck, C.H.6
  • 39
    • 38949154798 scopus 로고    scopus 로고
    • Fetal aberrant right subclavian artery in normal and Down syndrome fetuses
    • Zalel Y, Achiron R, Yagel S, Kivilevitch Z,. Fetal aberrant right subclavian artery in normal and Down syndrome fetuses. Ultrasound Obstet Gynecol 2008; 31: 25-29.
    • (2008) Ultrasound Obstet Gynecol , vol.31 , pp. 25-29
    • Zalel, Y.1    Achiron, R.2    Yagel, S.3    Kivilevitch, Z.4
  • 43
    • 59949090290 scopus 로고    scopus 로고
    • Second-trimester genetic sonogram for detection of fetal chromosomal abnormalities in a community-based antenatal testing unit
    • Bottalico JN, Chen X, Tartaglia M, Rosario B, Yarabothu D, Nelson L,. Second-trimester genetic sonogram for detection of fetal chromosomal abnormalities in a community-based antenatal testing unit. Ultrasound Obstet Gynecol 2009; 33: 161-168.
    • (2009) Ultrasound Obstet Gynecol , vol.33 , pp. 161-168
    • Bottalico, J.N.1    Chen, X.2    Tartaglia, M.3    Rosario, B.4    Yarabothu, D.5    Nelson, L.6
  • 44
    • 74749107303 scopus 로고    scopus 로고
    • Echogenic intracardiac foci: Associated with increased risk for fetal trisomy 21 or not?
    • Shanks AL, Odibo AO, Gray DL,. Echogenic intracardiac foci: associated with increased risk for fetal trisomy 21 or not? J Ultrasound Med 2009; 28: 1639-1643.
    • (2009) J Ultrasound Med , vol.28 , pp. 1639-1643
    • Shanks, A.L.1    Odibo, A.O.2    Gray, D.L.3
  • 45
    • 78349242537 scopus 로고    scopus 로고
    • Aberrant right subclavian artery at 16 to 23 + 6 weeks of gestation: A marker for chromosomal abnormality
    • Borenstein M, Minekawa R, Zidere V, Nicolaides KH, Allan LD,. Aberrant right subclavian artery at 16 to 23 + 6 weeks of gestation: a marker for chromosomal abnormality. Ultrasound Obstet Gynecol 2010; 36: 548-552.
    • (2010) Ultrasound Obstet Gynecol , vol.36 , pp. 548-552
    • Borenstein, M.1    Minekawa, R.2    Zidere, V.3    Nicolaides, K.H.4    Allan, L.D.5
  • 46
    • 77954855948 scopus 로고    scopus 로고
    • Intracardiac echogenic focus and trisomy 21 in a population previously evaluated by first-trimester combined screening
    • Huang SY, Shaw SW, Cheuh HY, Cheng PJ,. Intracardiac echogenic focus and trisomy 21 in a population previously evaluated by first-trimester combined screening. Acta Obstet Gynecol Scand 2010; 89: 1017-1023.
    • (2010) Acta Obstet Gynecol Scand , vol.89 , pp. 1017-1023
    • Huang, S.Y.1    Shaw, S.W.2    Cheuh, H.Y.3    Cheng, P.J.4
  • 47
    • 77957809155 scopus 로고    scopus 로고
    • Fetal facial sonographic markers for second trimester Down syndrome screening in a Thai population
    • Sooklim R, Manotaya S,. Fetal facial sonographic markers for second trimester Down syndrome screening in a Thai population. Int J Gynaecol Obstet 2010; 111: 144-147.
    • (2010) Int J Gynaecol Obstet , vol.111 , pp. 144-147
    • Sooklim, R.1    Manotaya, S.2
  • 49
    • 68049122102 scopus 로고    scopus 로고
    • Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009; 6: e1000097.
    • (2009) PLoS Med , vol.6
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 52
    • 0038742106 scopus 로고    scopus 로고
    • Diagnostic performance of intracardiac echogenic foci for Down syndrome: A meta-analysis
    • Sotiriadis A, Makrydimas G, Ioannidis JP,. Diagnostic performance of intracardiac echogenic foci for Down syndrome: a meta-analysis. Obstet Gynecol 2003; 101: 1009-1016.
    • (2003) Obstet Gynecol , vol.101 , pp. 1009-1016
    • Sotiriadis, A.1    Makrydimas, G.2    Ioannidis, J.P.3
  • 53
    • 0035961570 scopus 로고    scopus 로고
    • Second-trimester ultrasound to detect fetuses with Down syndrome: A meta-analysis
    • Smith-Bindman R, Hosmer W, Feldstein VA, Deeks JJ, Goldberg JD,. Second-trimester ultrasound to detect fetuses with Down syndrome: a meta-analysis. JAMA 2001; 285: 1044-1055.
    • (2001) JAMA , vol.285 , pp. 1044-1055
    • Smith-Bindman, R.1    Hosmer, W.2    Feldstein, V.A.3    Deeks, J.J.4    Goldberg, J.D.5
  • 54
    • 0035682245 scopus 로고    scopus 로고
    • Relationship between nuchal translucency at 11-14 weeks and nuchal fold at 20-24 weeks of gestation
    • Salomon LJ, Bernard JP, Taupin P, Benard C, Ville Y,. Relationship between nuchal translucency at 11-14 weeks and nuchal fold at 20-24 weeks of gestation. Ultrasound Obstet Gynecol 2001; 18: 636-637.
    • (2001) Ultrasound Obstet Gynecol , vol.18 , pp. 636-637
    • Salomon, L.J.1    Bernard, J.P.2    Taupin, P.3    Benard, C.4    Ville, Y.5
  • 56
    • 41149146371 scopus 로고    scopus 로고
    • Correlation between nuchal translucency and nuchal skin-fold measurements in Down syndrome and unaffected fetuses
    • Maymon R, Zimerman AL, Weinraub Z, Herman A, Cuckle H,. Correlation between nuchal translucency and nuchal skin-fold measurements in Down syndrome and unaffected fetuses. Ultrasound Obstet Gynecol 2008; 32: 501-505.
    • (2008) Ultrasound Obstet Gynecol , vol.32 , pp. 501-505
    • Maymon, R.1    Zimerman, A.L.2    Weinraub, Z.3    Herman, A.4    Cuckle, H.5
  • 58
    • 0028932931 scopus 로고
    • Adjusting the risk for trisomy 21 on the basis of second-trimester ultrasonography
    • Vintzileos AM, Egan JF,. Adjusting the risk for trisomy 21 on the basis of second-trimester ultrasonography. Am J Obstet Gynecol 1995; 172: 837-844.
    • (1995) Am J Obstet Gynecol , vol.172 , pp. 837-844
    • Vintzileos, A.M.1    Egan, J.F.2
  • 59
    • 0029278250 scopus 로고
    • Can the presumed risk of autosomal trisomy be decreased in fetuses or older women following a normal sonogram?
    • Nadel AS, Bromley B, Frigoletto FD Jr, Benacerraf BR,. Can the presumed risk of autosomal trisomy be decreased in fetuses or older women following a normal sonogram? J Ultrasound Med 1995; 14: 297-302.
    • (1995) J Ultrasound Med , vol.14 , pp. 297-302
    • Nadel, A.S.1    Bromley, B.2    Frigoletto, Jr.F.D.3    Benacerraf, B.R.4
  • 60
    • 0029957255 scopus 로고    scopus 로고
    • Risk of Down syndrome and any clinically significant chromosome defect in pregnancies with abnormal triple-screen and normal targeted ultrasonographic results
    • Bahado-Singh RO
    • Bahado-Singh RO, Tan A, Deren O, Hunter D, Copel J, Mahoney MJ,. Risk of Down syndrome and any clinically significant chromosome defect in pregnancies with abnormal triple-screen and normal targeted ultrasonographic results. Am J Obstet Gynecol 1996; 175: 824-829.
    • (1996) Am J Obstet Gynecol , vol.175 , pp. 824-829
    • Tan, A.1    Deren, O.2    Hunter, D.3    Copel, J.4    Mahoney, M.J.5
  • 61
    • 0037541122 scopus 로고    scopus 로고
    • Screening for chromosomal defects
    • Nicolaides KH,. Screening for chromosomal defects. Ultrasound Obstet Gynecol 2003; 21: 313-321.
    • (2003) Ultrasound Obstet Gynecol , vol.21 , pp. 313-321
    • Nicolaides, K.H.1


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