Interspecies extrapolation based on the RepDose database-A probabilistic approach

Toxicology Letters

Volumn 218, Issue 2, 2013, Pages 159-165

  Escher, Sylvia E ^a   Batke, Monika ^a   Hoffmann Doerr, Simone ^b   Messinger, Horst ^b   Mangelsdorf, Inge ^a  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^b BASF SE   (Germany)

Author keywords

Assessment factor; Interspecies; Probabilistic; Risk assessment

Indexed keywords

ALLOMETRY; ARTICLE; DATA BASE; EXPOSURE; HUMAN; MOUSE; NONHUMAN; NORMAL DISTRIBUTION; PRIORITY JOURNAL; RAT; REPDOSE DATABASE; RISK ASSESSMENT; SPECIES COMPARISON;

ADMINISTRATION, INHALATION; ANIMALS; DATABASES, FACTUAL; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INHALATION EXPOSURE; MICE; MODELS, STATISTICAL; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RATS; RISK ASSESSMENT; SPECIES SPECIFICITY;

EID: 84874725088     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.01.027     Document Type: Article

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