Time extrapolation and interspecies extrapolation for locally acting substances in case of limited toxicological data

Annals of Occupational Hygiene

Volumn 46, Issue 2, 2002, Pages 175-185

  Kalberlah, F ^a   Fost U ^b   Schneider, K ^a  

^a Res/Advsy Inst on Hazardous Subs   (Germany)

^b FEDERAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (Germany)

Author keywords

Interspecies extrapolation; Occupational exposure limits; Respiratory toxicity; Risk assessment; Time extrapolation

Indexed keywords

EXTRAPOLATION; MATHEMATICAL MODELS; OCCUPATIONAL RISKS; RISK ASSESSMENT; TOXICITY; ANIMALS; ENVIRONMENTAL PROTECTION AGENCY; MAMMALS;

INTERSPECIES EXTRAPOLATION;

HEALTH CARE; EXTRAPOLATION;

ACROLEIN; AMMONIA; CHLORINE; EPICHLOROHYDRIN; FORMALDEHYDE; NITROGEN OXIDE; OZONE; SULFUR DIOXIDE;

ARTICLE; CONCENTRATION (PARAMETERS); DOSIMETRY; ENVIRONMENTAL FACTOR; HISTOLOGY; HUMAN; LONG TERM EXPOSURE; LUNG TOXICITY; NONHUMAN; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OCCUPATIONAL TOXICOLOGY; PARTICLE SIZE; PARTICULATE MATTER; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; SEX DIFFERENCE; SPECIES DIFFERENCE; TOXICOKINETICS; ANIMAL; BIOMETRY; DANGEROUS GOODS; FEMALE; INHALATIONAL DRUG ADMINISTRATION; MALE; MOUSE; RAT; STANDARD; TIME;

ADMINISTRATION, INHALATION; ANIMALS; BIOMETRY; FEMALE; HAZARDOUS SUBSTANCES; HUMANS; MALE; MICE; OCCUPATIONAL EXPOSURE; RATS; RISK ASSESSMENT; SPECIES SPECIFICITY; TIME FACTORS;

EFFECT CONCENTRATION; GEOMETRIC MEAN VALUE; OCCUPATIONAL EXPOSURE LIMITS; QUALITATIVE PREDICTIONS; REFERENCE CONCENTRATION; UPPER RESPIRATORY TRACT; US ENVIRONMENTAL PROTECTION AGENCY; US NATIONAL TOXICOLOGY PROGRAMS;

EID: 0036490028     PISSN: 00034878     EISSN: None     Source Type: Journal    
DOI: 10.1093/annhyg/mef014     Document Type: Article

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