Plasma cysteine/cystine reduction potential correlates with plasma creatinine levels in chronic kidney disease

Blood Purification

Volumn 34, Issue 3-4, 2013, Pages 231-237

  Rodrigues, Silvia D ^a   Batista, Giuseppe B ^a   Ingberman, Max ^a   Pecoits Filho, Roberto ^b   Nakao, Lia S ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

Chronic kidney disease; Cysteine; Oxidative stress; Reduction potential; Uremia

Indexed keywords

CREATININE; CYSTEINE;

ADULT; AGED; AMINO ACID BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; COLORIMETRY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ELECTROCHEMICAL DETECTION; FEMALE; HEMODIALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; MALE; OXIDATION REDUCTION POTENTIAL; PHOTOMETRY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CREATININE; CYSTEINE; CYSTINE; FEMALE; HUMANS; MALE; MIDDLE AGED; OXIDATIVE STRESS; RENAL INSUFFICIENCY, CHRONIC; YOUNG ADULT;

EID: 84874684082     PISSN: 02535068     EISSN: 14219735     Source Type: Journal    
DOI: 10.1159/000342627     Document Type: Article

References (50)

1. Luke RG: Chronic renal failure-a vasculopathic state. N Engl J Med 1998; 339: 841-843. (Pubitemid 28447461)
2. Ikizler TA: Epidemiology of vascular disease in renal failure. Blood Purif 2002; 20: 6-10. (Pubitemid 34102502)
3. Yao Q, Pecoits-Filho R, Lindholm B, Stenvinkel P: Traditional and non-traditional risk factors as contributors to atherosclerotic cardiovascular disease in end-stage renal disease. Scand J Urol Nephrol 2004; 38: 405-416. (Pubitemid 39551351)
4. Halliwell B, Gutteridge JMC: Free Radicals in Biology and Medicine, ed 4. New York, Oxford University Press, 2007.
5. Himmelfarb J, McMonagle E, McMenamin E: Plasma protein thiol oxidation and carbonyl formation in chronic renal failure. Kidney Int 2000; 58: 2571-2578.
6. Himmelfarb J, Stenvinkel P, Ikizler TA, Hakim RM: The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int 2002; 62: 1524-1538. (Pubitemid 35286260)
7. Simmons EM, Langone A, Sezer MT, Vella JP, Recupero P, Morrow JD, Ikizler TA, Himmelfarb J: Effect of renal transplantation on biomarkers of inflammation and oxidative stress in end-stage renal disease patients. Transplantation 2005; 79: 914-919. (Pubitemid 40586863)
8. Aveles PR, Criminacio CR, Goncalves S, Bignelli AT, Claro LM, Siqueira SS, Nakao LS, Pecoits-Filho R: Association between biomarkers of carbonyl stress with increased systemic inflammatory response in different stages of chronic kidney disease and after renal transplantation. Nephron Clin Pract 2010; 116:c294-c299.
9. Matsuyama Y, Terawaki H, Terada T, Era S: Albumin thiol oxidation and serum protein carbonyl formation are progressively enhanced with advancing stages of chronic kidney disease. Clin Exp Nephrol 2009; 13: 308-315.
10. Witko-Sarsat V, Friedlander M, Capeillere- Blandin C, Nguyen-Khoa T, Nguyen AT, Zingraff J, Jungers P, Descamps-Latscha B: Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int 1996; 49: 1304-1313. (Pubitemid 26166404)
11. Clermont G, Lecour S, Lahet J, Siohan P, Vergely C, Chevet D, Rifle G, Rochette L: Alteration in plasma antioxidant capacities in chronic renal failure and hemodialysis patients: a possible explanation for the increased cardiovascular risk in these patients. Cardiovasc Res 2000; 47: 618-623. (Pubitemid 30646084)
12. Handelman GJ, Walter MF, Adhikarla R, Gross J, Dallal GE, Levin NW, Blumberg JB: Elevated plasma F2-isoprostanes in patients on long-term hemodialysis. Kidney Int 2001; 59: 1960-1966. (Pubitemid 32336813)
13. Himmelfarb J, McMenamin ME, Loseto G, Heinecke JW: Myeloperoxidase- catalyzed 3-chlorotyrosine formation in dialysis patients. Free Radic Biol Med 2001; 31: 1163-1169. (Pubitemid 33052491)
14. Massy ZA, Borderie D, Nguyen-Khoa T, Drueke TB, Ekindjian OG, Lacour B: Increased plasma S-nitrosothiol levels in chronic haemodialysis patients. Nephrol Dial Transplant 2003; 18: 153-157. (Pubitemid 36104492)
15. Vaziri ND, Dicus M, Ho ND, Boroujerdi-Rad L, Sindhu RK: Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency. Kidney Int 2003; 63: 179-185. (Pubitemid 35463919)
16. Gelasco AK, Raymond JR: Indoxyl sulfate induces complex redox alterations in mesangial cells. Am J Physiol Renal Physiol 2006; 290:F1551-F1558. (Pubitemid 43830783)
17. Dou L, Jourde-Chiche N, Faure V, Cerini C, Berland Y, Dignat-George F, Brunet P: The uremic solute indoxyl sulfate induces oxidative stress in endothelial cells. J Thromb Haemost 2007; 5: 1302-1308. (Pubitemid 46902134)
18. Jones DP: Redefining oxidative stress. Antioxid Redox Signal 2006; 8: 1865-1879. (Pubitemid 44726359)
19. Jones DP: Radical-free biology of oxidative stress. Am J Physiol Cell Physiol 2008; 295:C849-C868.
20. Schafer FQ, Buettner GR: Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med 2001; 30: 1191-1212. (Pubitemid 32463931)
21. Jones DP, Carlson JL, Mody VC, Cai J, Lynn MJ, Sternberg P: Redox state of glutathione in human plasma. Free Radic Biol Med 2000; 28: 625-635. (Pubitemid 30136044)
22. Jones DP, Mody VC Jr, Carlson JL, Lynn MJ, Sternberg P Jr: Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses. Free Radic Biol Med 2002; 33: 1290-1300. (Pubitemid 35246597)
23. Moriarty SE, Shah JH, Lynn M, Jiang S, Openo K, Jones DP, Sternberg P: Oxidation of glutathione and cysteine in human plasma associated with smoking. Free Radic Biol Med 2003; 35: 1582-1588. (Pubitemid 37532909)
24. Go YM, Jones DP: Intracellular proatherogenic events and cell adhesion modulated by extracellular thiol/disulfide redox state. Circulation 2005; 111: 2973-2980. (Pubitemid 40814191)
25. Iyer SS, Accardi CJ, Ziegler TR, Blanco RA, Ritzenthaler JD, Rojas M, Roman J, Jones DP: Cysteine redox potential determines pro-inflammatory IL-1beta levels. PLoS One 2009; 4:e5017.
26. Ramirez A, Ramadan B, Ritzenthaler JD, Rivera HN, Jones DP, Roman J: Extracellular cysteine/cystine redox potential controls lung fibroblast proliferation and matrix expression through upregulation of transforming growth factor-beta. Am J Physiol Lung Cell Mol Physiol 2007; 293:L972-L981. (Pubitemid 47572245)
27. Jocelyn PC: Chemical reduction of disulfides. Methods Enzymol 1987; 143: 246-256.
28. Buege JA, Aust SD: Microsomal lipid peroxidation. Methods Enzymol 1978; 52: 302-310.
29. Jones DP, Park Y, Gletsu-Miller N, Liang Y, Yu T, Accardi CJ, Ziegler TR: Dietary sulfur amino acid effects on fasting plasma cysteine/ cystine redox potential in humans. Nutrition 2011; 27: 199-205.
30. Park Y, Ziegler TR, Gletsu-Miller N, Liang Y, Yu T, Accardi CJ, Jones DP: Postprandial cysteine/cystine redox potential in human plasma varies with meal content of sulfur amino acids. J Nutr 2010; 140: 760-765.
31. Melnyk S, Pogribna M, Pogribny I, Hine RJ, James SJ: A new HPLC method for the simultaneous determination of oxidized and reduced plasma aminothiols using coulometric electrochemical detection. J Nutr Biochem 1999; 10: 490-497. (Pubitemid 29378307)
32. Petrlova J, Mikelova R, Stejskal K, Kleckerova A, Zitka O, Petrek J, Havel L, Zehnalek J, Vojtech A, Trnkova L, Kizek R: Simultaneous determination of eight biologically active thiol compounds using gradient elutionliquid chromatography with Coul-Array detection. J Sep Sci 2006; 29: 1166-1173. (Pubitemid 43871372)
33. Kleinman WA, Richie JP Jr: Status of glutathione and other thiols and disulfides in human plasma. Biochem Pharmacol 2000; 60: 19-29. (Pubitemid 30243081)
34. Gaitonde MK: A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids. Biochem J 1967; 104: 627-633.
35. Babu CK, Ansari KM, Mehrotra S, Khanna R, Khanna SK, Das M: Alterations in redox potential of glutathione/glutathione disulfide and cysteine/cysteine disulfide couples in plasma of dropsy patients with argemone oil poisoning. Food Chem Toxicol 2008; 46: 2409-2414.
36. Wlodek PJ, Smolenski OB, Chwatko G, Iciek MB, Milkowski A, Bald E, Wlodek L: Disruption of thiol homeostasis in plasma of terminal renal failure patients. Clin Chim Acta 2006; 366: 137-145. (Pubitemid 43330974)
37. Wlodek PJ, Iciek MB, Milkowski A, Smolenski OB: Various forms of plasma cysteine and its metabolites in patients undergoing hemodialysis. Clin Chim Acta 2001; 304: 9-18. (Pubitemid 32124734)
38. Vanholder R, Baurmeister U, Brunet P, Cohen G, Glorieux G, Jankowski J: A bench to bedside view of uremic toxins. J Am Soc Nephrol 2008; 19: 863-870.
39. Himmelfarb J: Uremic toxicity, oxidative stress, and hemodialysis as renal replacement therapy. Semin Dial 2009; 22: 636-643.
40. Niwa T: Uremic toxicity of indoxyl sulfate. Nagoya J Med Sci 2010; 72: 1-11.
41. Cendoroglo M, Jaber BL, Balakrishnan VS, Perianayagam M, King AJ, Pereira BJ: Neutrophil apoptosis and dysfunction in uremia. J Am Soc Nephrol 1999; 10: 93-100. (Pubitemid 29034947)
42. Galli F, Ghibelli L, Buoncristiani U, Bordoni V, D'Intini V, Benedetti S, Canestrari F, Ronco C, Floridi A: Mononuclear leukocyte apoptosis in haemodialysis patients: the role of cell thiols and vitamin E. Nephrol Dial Transplant 2003; 18: 1592-1600. (Pubitemid 36939634)
43. Serradell M, Diaz-Ricart M, Cases A, Zurbano MJ, Lopez-Pedret J, Arranz O, Ordinas A, Escolar G: Uremic medium causes expression, redistribution and shedding of adhesion molecules in cultured endothelial cells. Haematologica 2002; 87: 1053-1061. (Pubitemid 35192217)
44. Diaz-Buxo JA, Woods HF: Protecting the endothelium: a new focus for management of chronic kidney disease. Hemodial Int 2006; 10: 42-48. (Pubitemid 43263290)
45. Di Marco GS, Hausberg M, Hillebrand U, Rustemeyer P, Wittkowski W, Lang D, Pavenstadt H: Increased inorganic phosphate induces human endothelial cell apoptosis in vitro. Am J Physiol Renal Physiol 2008; 294:F1381-F1387.
46. Muteliefu G, Enomoto A, Jiang P, Takahashi M, Niwa T: Indoxyl sulphate induces oxidative stress and the expression of osteoblastspecific proteins in vascular smooth muscle cells. Nephrol Dial Transplant 2009; 24: 2051-2058.
47. Stinghen AE, Goncalves SM, Martines EG, Nakao LS, Riella MC, Aita CA, Pecoits-Filho R: Increased plasma and endothelial cell expression of chemokines and adhesion molecules in chronic kidney disease. Nephron Clin Pract 2009; 111:c117-c126.
48. Caimi G, Carollo C, Montana M, Iatrino R, Bondi B, Lo Presti R: Nitric oxide metabolites, leukocyte activation markers and oxidative status in dialyzed subjects. Blood Purif 2009; 27: 194-198.
49. Peskin AV, Winterbourn CC: Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate. Free Radic Biol Med 2001; 30: 572-579. (Pubitemid 32162964)
50. Kim HJ, Vaziri ND: Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. Am J Physiol Renal Physiol 2010; 298:F662-F671.