H3.3 G34R mutations in pediatric primitive neuroectodermal tumors of central nervous system (CNS-PNET) and pediatric glioblastomas: Possible diagnostic and therapeutic implications?

Journal of Neuro-Oncology

Volumn 112, Issue 1, 2013, Pages 67-72

  Gessi, Marco ^a   Gielen, Gerrit H ^a   Hammes, Jennifer ^a   Dörner, Evelyn ^a   Mühlen, Anja Zur ^a   Waha, Andreas ^a   Pietsch, Torsten ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

CNS PNET; Glioblastoma; H3.3; MLPA; Mutations; Pediatric primitive neuroectodermal tumors; Pyrosequencing

Indexed keywords

ARGININE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLYCINE; HISTONE H3; METHIONINE; MICROTUBULE ASSOCIATED PROTEIN 2; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR;

ADOLESCENT; ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CDKN2A GENE; CHILD; CHROMOSOME 20Q; CHROMOSOME 4P; CHROMOSOME 4Q; CHROMOSOME DELETION; CHROMOSOME DELETION 14Q31; CHROMOSOME DELETION 14Q32; CHROMOSOME DELETION 21Q22; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; EGFR GENE; FEMALE; GENE AMPLIFICATION; GENE LOCUS; GENE LOSS; GENE MUTATION; GENETIC GAIN; GLIOBLASTOMA; H3.3 GENE; HOMOZYGOSITY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; MUTATIONAL ANALYSIS; NEUROECTODERM TUMOR; PDGFR ALPHA GENE; PRESCHOOL CHILD; PRIMITIVE NEUROECTODERMAL TUMOR OF THE CENTRAL NERVOUS SYSTEM; PYROSEQUENCING; SCHOOL CHILD; TUMOR DIAGNOSIS;

ADOLESCENT; ARGININE; CENTRAL NERVOUS SYSTEM NEOPLASMS; CHILD; CHILD, PRESCHOOL; DNA MUTATIONAL ANALYSIS; FEMALE; GLIOBLASTOMA; GLYCINE; HISTONES; HUMANS; MALE; MUTATION; NEUROECTODERMAL TUMORS, PRIMITIVE; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA;

EID: 84874659208     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-012-1040-z     Document Type: Article

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