Amberlite IR-120H catalyzed MCR: Design, synthesis and crystal structure analysis of 1,8-dioxodecahydroacridines as potential inhibitors of sirtuins

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 6, 2013, Pages 1828-1833

  Nakhi, Ali ^a   Srinivas, P T V A ^b   Rahman, Md Shafiqur ^a,c   Kishore, Ravada ^d   Seerapu, G P K ^a   Lalith Kumar, K ^a   Haldar, Devyani ^a   Rao, M V Basaveswara ^e   Pal, Manojit ^a  

^a INSTITUTE OF LIFE SCIENCES   (India)

^b K L UNIVERSITY   (India)

^c UNIVERSITY OF DELHI   (India)

^d UNIVERSITY OF HYDERABAD   (India)

^e KRISHNA UNIVERSITY   (India)

Author keywords

Acridine; Amberlite IR 120H; Cancer; MCR; Sirtuin

Indexed keywords

1,8 DIOXODECAHYDROACRIDINE DERIVATIVE; 5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; ACRIDINE DERIVATIVE; ANTINEOPLASTIC AGENT; POLACRILIN; PROTEIN INHIBITOR; SILENT INFORMATION REGULATOR PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; CATALYST; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; IN VITRO STUDY; NONHUMAN; PROTEIN BINDING; STRUCTURE ANALYSIS; YEAST CELL;

ACRIDINES; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HISTONE DEACETYLASE INHIBITORS; HYDROGEN BONDING; MOLECULAR CONFORMATION; MOLECULAR DOCKING SIMULATION; PALLADIUM; PROTEIN STRUCTURE, TERTIARY; RESINS, SYNTHETIC; SACCHAROMYCES CEREVISIAE; SIRTUINS;

EID: 84874655200     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.01.026     Document Type: Article

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