Optimization of chemotherapy and immunotherapy: In silico analysis using pharmacokinetic-pharmacodynamic and tumor growth models

Journal of Process Control

Volumn 23, Issue 3, 2013, Pages 396-403

  Kiran, Kanchi Lakshmi ^a   Lakshminarayanan, S ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Cancer; Chemotherapy; Immunotherapy; Mathematical model; Multi objective optimization; Non dominated sorting genetic algorithm

Indexed keywords

CANCER; CANCER PATIENTS; COMBINATION THERAPY; DOXORUBICIN; IMMUNE CELLS; IMMUNOTHERAPY; IN-SILICO; MULTI OBJECTIVE OPTIMIZATIONS (MOO); MULTI-OBJECTIVE OPTIMIZATION PROBLEM; NON-DOMINATED SORTING GENETIC ALGORITHMS; NOVEL STRATEGIES; SIDE EFFECT; TREATMENT MODALITY; TUMOR CELLS; TUMOR GROWTH; TUMOR GROWTH MODELS; TUMOR REGRESSION; TUMOR SIZE;

CHEMOTHERAPY; DISEASES; MATHEMATICAL MODELS; MULTIOBJECTIVE OPTIMIZATION; TUMORS;

PATIENT TREATMENT;

EID: 84874630593     PISSN: 09591524     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jprocont.2012.12.006     Document Type: Article

References (40)

1. L.J. Kleinsmith Principles of Cancer Biology 2005 Pearson San Francisco
2. D.I. Gabrilovich Combination of chemotherapy and immunotherapy for cancer: a paradigm revisited The Lancet Oncology 8 2007 2 3 (Pubitemid 44943085)
3. R.A. Lake, and B.W.S. Robinson Immunotherapy and chemotherapy-a practical partnership Nature Reviews Cancer 5 2005 397 405
4. J.K. Adam, B. Odhav, and K.D. Bhoola Immune responses in cancer Pharmacology & Therapeutics 99 2003 113 132 (Pubitemid 36700437)
5. S.A. Rosenberg, N.P. Restifo, J.C. Yang, R.A. Morgan, and M.E. Dudley Adoptive cell transfer: a clinical path to effective cancer immunotherapy Nature Reviews Cancer 8 2008 299 308 (Pubitemid 351430867)
6. M.E. Dudley, and S.A. Rosenberg Adoptive-cell-transfer therapy for the treatment of patients with cancer Nature Reviews Cancer 3 2003 666 675 (Pubitemid 37328821)
7. W.Y. Ho, J.N. Blattman, M.L. Dossett, C. Yee, and P.D. Greenberg Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction Cancer Cell 3 2003 431 437 (Pubitemid 38340289)
8. M.E. Dudley, J.R. Wunderlich, P.F. Robbins, J.C. Yang, P. Hwu, D.J. Schwartzentruber, S.L. Topalian, R. Sherry, N.P. Restifo, A.M. Hubicki, M.R. Robinson, M. Raffeld, P. Duray, C.A. Seipp, L. Rogers-Freezer, K.E. Morton, S.A. Mavroukakis, D.E. White, and S.A. Rosenberg Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes Science 298 2002 850 854 (Pubitemid 35231542)
9. N. Holford, S.C. Ma, and B.A. Ploeger Clinical trial simulation: a review Clinical Pharmacology and Therapeutics 88 2010 166 182
10. C. Lord, and A. Ashworth Biology-driven cancer drug development: back to the future BMC Biology 8 2010 38
11. S.F. Hudachek, and D.L. Gustafson Customized in silico population mimics actual population in docetaxel population pharmacokinetic analysis Journal of Pharmaceutical Sciences 100 2011 1156 1166
12. M. Eisen Mathematical Models in Cell Biology and Cancer Chemotherapy 1979 Springer-Verlag Berlin/New York
13. G.W. Swan Optimal control of drug administration in cancer chemotherapy Bulletin of Mathematical Biology 57 1995 503 504
14. A. Swierniak, M. Kimmel, and J. Smieja Mathematical modeling as a tool for planning anticancer therapy European Journal of Pharmacology 625 2009 108 121
15. V.F. Smolen, B.D. Turrie, and W.A. Welgand Drug input optimization: bioavailability-effected time-optimal control of multiple, simultaneous, pharmacological effects and their interrelationships Journal of Pharmaceutical Sciences 61 1972 1941 1952
16. R.B. Martin Optimal control drug scheduling of cancer chemotherapy Automatica 28 1992 1113 1123 (Pubitemid 23587963)
17. A. Cappuccio, F. Castiglione, and B. Piccoli Determination of the optimal therapeutic protocols in cancer immunotherapy Mathematical Biosciences 209 2007 1 13 (Pubitemid 47238117)
18. D. Barbolosi, and A. Iliadis Optimizing drug regimens in cancer chemotherapy: a simulation study using a PK-PD model Computers in Biology and Medicine 31 2001 157 172 (Pubitemid 32149922)
19. P. Dua, V. Dua, and E.N. Pistikopoulos Optimal delivery of chemotherapeutic agents in cancer Computers & Chemical Engineering 32 2008 99 107 (Pubitemid 350016267)
20. A. Ghaffari, and N. Naserifar Optimal therapeutic protocols in cancer immunotherapy Computers in Biology and Medicine 40 2010 261 270
21. S. Chareyron, and M. Alamir Mixed immunotherapy and chemotherapy of tumors: feedback design and model updating schemes Journal of Theoretical Biology 258 2009 444 454
22. L.G. de Pillis, W. Gu, and A.E. Radunskaya Mixed immunotherapy and chemotherapy of tumors: modeling, applications and biological interpretations Journal of Theoretical Biology 238 2006 841 862 (Pubitemid 43175834)
23. K.L. Kiran, D. Jayachandran, and S. Lakshminarayanan Multi-objective optimization of cancer immuno-chemotherapy 13th International Conference on Biomedical Engineering 2009 1337 1340
24. S.-M. Tse, Y. Liang, K.-S. Leung, K.-H. Lee, and T.S.-K. Mok A memetic algorithm for multiple-drug cancer chemotherapy schedule optimization IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics 37 2007 84 91 (Pubitemid 46358483)
25. J. McCall, A. Petrovski, and S. Shakya Evolutionary algorithms for cancer chemotherapy optimization G.B. Fogel, D.W. Corne, Y. Pan, Computational Intelligence in Bioinformatics 2007 263 296
26. K.L. Kiran, and S. Lakshminarayanan Treatment planning of cancer dendritic cell therapy using multi-objective optimization Proceedings of ADCHEM 2009 Istanbul, Turkey 2009
27. N. Bellomo, and L. Preziosi Modelling and mathematical problems related to tumor evolution and its interaction with the immune system Mathematical and Computer Modelling 32 2000 413 452 (Pubitemid 30610360)
28. D. Kirschner, and J.C. Panetta Modeling immunotherapy of the tumor-immune interaction Journal of Mathematical Biology 37 1998 235 252
29. F. Castiglione, and B. Piccoli Cancer immunotherapy, mathematical modeling and optimal control Journal of Theoretical Biology 247 2007 723 732 (Pubitemid 47081044)
30. R.J. De Boer, and P. Hogeweg Interactions between macrophages and T-lymphocytes: tumor sneaking through intrinsic to helper T cell dynamics Journal of Theoretical Biology 120 1986 331 351 (Pubitemid 16099217)
31. A. Matzavinos, M.A.J. Chaplain, and V.A. Kuznetsov Mathematical modelling of the spatio-temporal response of cytotoxic T-lymphocytes to a solid tumour Mathematical Medicine and Biology 21 2004 1 34 (Pubitemid 38380172)
32. V.A. Kuznetsov, I.A. Makalkin, M.A. Taylor, and A.S. Perelson Nonlinear dynamics of immunogenic tumors: parameter estimation and global bifurcation analysis Bulletin of Mathematical Biology 56 1994 295 321
33. V.A. Kuznetsov, and G.D. Knott Modeling tumor regrowth and immunotherapy Mathematical and Computer Modelling 33 2001 1275 1287 (Pubitemid 32417937)
34. L. de Pillis, K. Renee Fister, W. Gu, C. Collins, M. Daub, D. Gross, J. Moore, and B. Preskill Mathematical model creation for cancer chemo-immunotherapy Computational and Mathematical Methods in Medicine: An Interdisciplinary Journal of Mathematical, Theoretical and Clinical Aspects of Medicine 10 2009 165 184
35. H. Siu, E. Vitetta, R. May, and J. Uhr Tumor dormancy. I. Regression of BCL1 tumor and induction of a dormant tumor state in mice chimeric at the major histocompatibility complex Journal of Immunology 137 1986 1376 1382 (Pubitemid 16041132)
36. H. Tamaki, H. Kita, and S. Kobayashi Multi-objective optimization by genetic algorithms: a review Proceedings of IEEE International Conference on Evolutionary Computation 1996 517 522
37. G.L. Nemhauser, A.H.G. Rinnooy Kan, and M.J. Todd Optimization 1989 North-Holland Amsterdam
38. K. Deb, S. Agrawal, A. Pratap, and T. Meyarivan A Fast Elitist Non-dominated Sorting Genetic Algorithm for Multi-objective Optimization: NSGA-II 2000 Springer-Verlag Paris, France pp. 849-858
39. E.M. Kasprzak, and K.E. Lewis Pareto analysis in multiobjective optimization using the collinearity theorem and scaling method Structural and Multidisciplinary Optimization 22 2001 208 218 (Pubitemid 33046331)
40. P.G. Rose Pegylated liposomal doxorubicin: optimizing the dosing schedule in ovarian cancer Oncologist 10 2005 205 214 (Pubitemid 40463158)