Microfluidic screening of electrophoretic mobility shifts elucidates riboswitch binding function

Journal of the American Chemical Society

Volumn 135, Issue 8, 2013, Pages 3136-3143

  Karns, Kelly ^a   Vogan, Jacob M ^a   Qin, Qian ^a   Hickey, Scott F ^a   Wilson, Stephen C ^a   Hammond, Ming C ^a   Herr, Amy E ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California at Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; DISSOCIATION; EQUILIBRIUM CONSTANTS; GENE EXPRESSION; LIGANDS; METABOLITES; MICROFLUIDICS;

CONFORMATIONAL CHANGE; ELECTROPHORETIC MOBILITY SHIFT; EQUILIBRIUM DISSOCIATION CONSTANT; HIGH-RESOLUTION SEPARATIONS; MOBILITY SHIFT ASSAYS; QUANTITATIVE SCREENING; REGULATORY FUNCTIONS; STATISTICAL ASSESSMENT;

ELECTROPHORETIC MOBILITY;

APTAMER; BACTERIAL RNA;

ARTICLE; BACILLUS SUBTILIS; BACTERIUM; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; DISSOCIATION CONSTANT; ELECTROPHORETIC MOBILITY; LIGAND BINDING; MICROFLUIDIC ANALYSIS; NONHUMAN; POLARIBACTER IRGENSII; QUANTITATIVE ANALYSIS; RIBOSWITCH; RNA BINDING; RNA CONFORMATION;

EID: 84874611408     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja310742m     Document Type: Article

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