Attenuation of Hind-Limb Ischemia in Mice with Endothelial-Like Cells Derived from Different Sources of Human Stem Cells

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Lai, Wing Hon ^a   Ho, Jenny C Y ^a,b   Chan, Yau Chi ^a   Ng, Joyce H L ^a   Au, Ka Wing ^a   Wong, Lai Yung ^a   Siu, Chung Wah ^a,b   Tse, Hung Fat ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; LECTIN; LOW DENSITY LIPOPROTEIN; PLACENTAL GROWTH FACTOR; SCATTER FACTOR; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN; ANGIOGENIC PROTEIN; CULTURE MEDIUM; CYTOKINE;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; BONE MARROW MONONUCLEAR CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL MIGRATION; CELL TRANSPLANTATION; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE SEVERITY; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; HINDLIMB ISCHEMIA; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; LIMB ISCHEMIA; MALE; MONONUCLEAR CELL; MORPHOLOGY; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PLURIPOTENT STEM CELL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN TRANSPORT; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; ANGIOGENESIS; ANIMAL; BONE MARROW CELL; CELL HYPOXIA; COMPARATIVE STUDY; CULTURE MEDIUM; CYTOLOGY; HINDLIMB; ISCHEMIA; METABOLISM; MIDDLE AGED; PATHOLOGY; PERFUSION; PHARMACOLOGY; STEM CELL TRANSPLANTATION; TIME; TRANSPLANTATION;

AGED; ANGIOGENIC PROTEINS; ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL HYPOXIA; CULTURE MEDIA, CONDITIONED; CYTOKINES; ENDOTHELIAL CELLS; HINDLIMB; HUMANS; INDUCED PLURIPOTENT STEM CELLS; ISCHEMIA; MALE; MICE; MIDDLE AGED; NEOVASCULARIZATION, PHYSIOLOGIC; PERFUSION; STEM CELL TRANSPLANTATION; TIME FACTORS;

EID: 84874592081     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057876     Document Type: Article

References (26)

1. Tse HF, Siu CW, Zhu SG, Songyan L, Zhang QY, et al. (2007) Paracrine effects of direct intramyocardial implantation of bone marrow derived cells to enhance neovascularization in chronic ischemic myocardium. Eur J Heart Fail 9: 747-753.
2. Tse HF, Kwong YL, Chan JK, Lo G, Ho CL, et al. (2003) Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet 361: 47-49.
3. Kang S, Yang YJ, Li CJ, Gao RL, (2008) Effects of intracoronary autologous bone marrow cells on left ventricular function in acute myocardial infarction: a systematic review and meta-analysis for randomized controlled trials. Coron Artery Dis 19: 327-335.
4. Martin-Rendon E, Brunskill SJ, Hyde CJ, Stanworth SJ, Mathur A, et al. (2008) Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review. Eur Heart J 29: 1807-1818.
5. Dimmeler S, Leri A, (2008) Aging and disease as modifiers of efficacy of cell therapy. Circ Res 102: 1319-1330.
6. Fortini C, Toffoletto B, Fucili A, Puppato E, Olivares A, et al. (2010) Circulating stem cell vary with nyha stage in heart failure patients. J Cell Mol Med 15: 1726-1736.
7. Li M, Ho JC, Lai KW, Au KK, Xu A, et al. (2011) The decrement in circulating endothelial progenitor cells (EPCs) in type 2 diabetes is independent of the severity of the hypoadiponectemia. Diabetes Metab Res Rev 27: 185-194.
8. Vasa M, Fichtlscherer S, Aicher A, Adler K, Urbich C, et al. (2001) Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 89: E1-7.
9. Cho SW, Moon SH, Lee SH, Kang SW, Kim J, et al. (2007) Improvement of postnatal neovascularization by human embryonic stem cell derived endothelial-like cell transplantation in a mouse model of hindlimb ischemia. Circulation 116: 2409-2419.
10. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
11. Yamanaka S, (2007) Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell 1: 39-49.
12. Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, et al. (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318: 1917-1920.
13. Li Z, Hu S, Ghosh Z, Han Z, Wu JC, (2011) Functional Characterization and Expression Profiling of Human Induced Pluripotent Stem Cell- and Embryonic Stem Cell-Derived Endothelial Cells. Stem Cells Dev 20: 1701-1710.
14. Lai WH, Ho JC, Lee YK, Ng KM, Au KW, et al. (2010) ROCK inhibition facilitates the generation of human-induced pluripotent stem cells in a defined, feeder-, and serum-free system. Cell Reprogram 12: 641-653.
15. Tse HF, Thambar S, Kwong YL, Rowlings P, Bellamy G, et al. (2007) Prospective randomized trial of direct endomyocardial implantation of bone marrow cells for treatment of severe coronary artery diseases (PROTECT-CAD trial). Eur Heart J 28: 2998-3005.
16. Limbourg A, Korff T, Napp LC, Schaper W, Drexler H, et al. (2009) Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia. Nat Protoc 4: 1737-1746.
17. Yoon CH, Hur J, Park KW, Kim JH, Lee CS, et al. (2005) Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases. Circulation 112: 1618-1627.
18. Siu CW, Tse HF, (2012) Cardiac regeneration: messages from CADUCEUS. Lancet. 379: 870-1.
19. Seifinejad A, Tabebordbar M, Baharvand H, Boyer LA, Salekdeh GH, (2010) Progress and promise towards safe induced pluripotent stem cells for therapy. Stem Cell Rev 6: 297-306.
20. Schultz A, Lavie L, Hochberg I, Beyar R, Stone T, et al. (1999) Interindividual heterogeneity in the hypoxic regulation of VEGF: significance for the development of the coronary artery collateral circulation. Circulation 100: 547-552.
21. Kim SW, Kim H, Cho HJ, Lee JU, Levit R, et al. (2010) Human peripheral blood-derived CD31+ cells have robust angiogenic and vasculogenic properties and are effective for treating ischemic vascular disease. J Am Coll Cardiol 56: 593-607.
22. Kim MH, Jin E, et al. (2011) Robust angiogenic properties of cultured human peripheral blood-derived CD31(+) cells. Int J Cardiol. 2011 Dec 19. [Epub ahead of print].
23. Bhang SH, Lee S, Lee TJ, La WG, Yang HS, et al. (2012) Three-dimensional cell grafting enhances the angiogenic efficacy of human umbilical vein endothelial cells. Tissue Eng Part A. 18: 310-319.
24. Zhou T, Benda C, Duzinger S, Huang Y, Li X, et al. (2011) Generation of induced pluripotent stem cells from urine. J Am Soc Nephrol 22: 1221-1228.
25. Novak A, Shtrichman R, Germanguz I, Segev H, Zeevi-Levin N, et al. (2010) Enhanced reprogramming and cardiac differentiation of human keratinocytes derived from plucked hair follicles, using a single excisable lentivirus. Cell Reprogram 12: 665-678.
26. Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, et al. (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7: 618-630.