Hematoma expansion following acute intracerebral hemorrhage

Cerebrovascular Diseases

Volumn 35, Issue 3, 2013, Pages 195-201

  Brouwers, H Bart ^a   Greenberg, Steven M ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Clinical trials; CT angiography spot sign; Functional outcome; Hematoma expansion; Intracerebral hemorrhage

Indexed keywords

RECOMBINANT BLOOD CLOTTING FACTOR 7A; APOLIPOPROTEIN E; CORTICOSTEROID;

ANEURYSM; ARTERIOVENOUS MALFORMATION; BRAIN HEMORRHAGE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; HEMATOMA; HUMAN; NEOPLASM; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RISK FACTOR; BRAIN HEMATOMA; CLINICAL EFFECTIVENESS; CLINICAL TRIAL (TOPIC); CORTICOSTEROID THERAPY; FUTUROLOGY; INTERVENTION STUDY; MATHEMATICAL MODEL; MINIMALLY INVASIVE SURGERY; MORBIDITY; NEUROIMAGING; PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); SIMULATION; SYSTEMATIC REVIEW (TOPIC); TREATMENT OUTCOME;

ACUTE DISEASE; CEREBRAL ANGIOGRAPHY; CEREBRAL HEMORRHAGE; CLINICAL TRIALS AS TOPIC; HEMATOMA; HUMANS; STROKE;

EID: 84874586293     PISSN: 10159770     EISSN: 14219786     Source Type: Journal    
DOI: 10.1159/000346599     Document Type: Review

References (54)

1. Qureshi AI, Mendelow AD, Hanley DF: In-tracerebral haemorrhage. Lancet 2009; 373: 1632-1644.
2. van Asch CJ, Luitse MJ, Rinkel GJ, van der Tweel I, Algra A, Klijn CJ: Incidence, case fatality, and functional outcome of intracere-bral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol 2010; 9:167-176.
3. Broderick JP, Brott TG, Duldner JE, Tomsick T, Huster G: Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality. Stroke 1993; 24:987-993.
4. Flaherty ML, Haverbusch M, Sekar P, Kissela B, Kleindorfer D, Moomaw CJ, et al: Longterm mortality after intracerebral hemorrhage. Neurology 2006; 66:1182-1186.
5. Davis SM, Broderick J, Hennerici M, Brun NC, Diringer MN, Mayer SA, et al: Hemato-ma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage. Neurology 2006; 66:1175-1181.
6. Dowlatshahi D, Demchuk AM, Flaherty ML, Ali M, Lyden PL, Smith EE, et al: Defining he-matoma expansion in intracerebral hemorrhage: relationship with patient outcomes. Neurology 2011; 76:1238-1244.
7. Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al: Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 2008; 358:2127-2137.
8. Delcourt C, Huang Y, Wang J, Heeley E, Lind-ley R, Stapf C, et al: The second (main) phase of an open, randomised, multicentre study to investigate the effectiveness of an intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT2). Int J Stroke 2010; 5:110-116.
9. Qureshi AI, Palesch YY: Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) II: design, methods, and rationale. Neurocrit Care 2011; 15:559-576.
10. Mayer SA, Davis SM, Skolnick BE, Brun NC, Begtrup K, Broderick JP, et al: Can a subset of intracerebral hemorrhage patients benefit from hemostatic therapy with recombinant activated factor VII? Stroke 2009; 40:833-840.
11. Ginde AA, Foianini A, Renner DM, Valley M, Camargo CA Jr: Availability and quality of computed tomography and magnetic resonance imaging equipment in US emergency departments. Acad Emerg Med 2008; 15:780-783.
12. Divani AA, Majidi S, Luo X, Souslian FG, Zhang J, Abosch A, et al: The ABCs of accurate volumetric measurement of cerebral he-matoma. Stroke 2011; 42:1569-1574.
13. Delgado Almandoz JE, Romero JM: Advanced CT imaging in the evaluation of hem-orrhagic stroke. Neuroimaging Clin N Am 2011; 21:197-213, ix.
14. Goldstein JN, Fazen LE, Snider R, Schwab K, Greenberg SM, Smith EE, et al: Contrast extravasation on CT angiography predicts he-matoma expansion in intracerebral hemorrhage. Neurology 2007; 68:889-894.
15. Wada R, Aviv RI, Fox AJ, Sahlas DJ, Gladstone DJ, Tomlinson G, et al: CT angiography 'spot sign' predicts hematoma expansion in acute intracerebral hemorrhage. Stroke 2007; 38:1257-1262.
16. Demchuk AM, Dowlatshahi D, Rodriguez-Luna D, Molina CA, Blas YS, Dzialowski I, et al: Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational study. Lancet Neurol 2012; 11:307-314.
17. Kidwell CS, Chalela JA, Saver JL, Starkman S, Hill MD, Demchuk AM, et al: Comparison of MRI and CT for detection of acute intracere-bral hemorrhage. JAMA 2004; 292:1823-1830.
18. Greenberg SM, Eng JA, Ning M, Smith EE, Rosand J: Hemorrhage burden predicts recurrent intracerebral hemorrhage after lobar hemorrhage. Stroke 2004; 35:1415-1420.
19. Greenberg SM, Vernooij MW, Cordonnier C, Viswanathan A, Al-Shahi Salman R, Warach S, et al: Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol 2009; 8:165-174.
20. Brott T, Broderick J, Kothari R, Barsan W, Tomsick T, Sauerbeck L, et al: Early hemorrhage growth in patients with intracerebral hemorrhage. Stroke 1997; 28:1-5.
21. Mayer SA: Ultra-early hemostatic therapy for intracerebral hemorrhage. Stroke 2003; 34: 224-229.
22. Brouwers HB, Falcone GJ, McNamara KA, Ayres AM, Oleinik A, Schwab K, et al: CTA spot sign predicts hematoma expansion in patients with delayed presentation after intrace-rebral hemorrhage. Neurocrit Care 2012; 17: 421-428.
23. Kim J, Smith A, Hemphill JC3rd, Smith WS, Lu Y, Dillon WP, et al: Contrast extravasation on CT predicts mortality in primary intrace-rebral hemorrhage. AJNR Am J Neuroradiol 2008; 29:520-525.
24. Fisher CM: Pathological observations in hypertensive cerebral hemorrhage. J Neuro-pathol Exp Neurol 1971; 30:536-550.
25. Greenberg SM, Nandigam RN, Delgado P, Betensky RA, Rosand J, Viswanathan A, et al: Microbleeds versus macrobleeds: evidence for distinct entities. Stroke 2009; 40:2382-2386.
26. Brouwers HB, Biffi A, Ayres AM, Schwab K, Cortellini L, Romero JM, et al: Apolipopro-tein E genotype predicts hematoma expansion in lobar intracerebral hemorrhage. Stroke 2012; 43:1490-1495.
27. Greenberg SM, Vonsattel JP, Segal AZ, Chiu RI, Clatworthy AE, Liao A, et al: Association of apolipoprotein E epsilon2 and vasculopa-thy in cerebral amyloid angiopathy. Neurology 1998; 50:961-965.
28. McCarron MO, Nicoll JA, Stewart J, Ironside JW, Mann DM, Love S, et al: The apolipopro-tein E epsilon2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage. J Neuropathol Exp Neurol 1999; 58:711-718.
29. Delgado Almandoz JE, Yoo AJ, Stone MJ, Schaefer PW, Goldstein JN, Rosand J, et al: Systematic characterization of the computed tomography angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: the spot sign score. Stroke 2009; 40: 2994-3000.
30. Brouwers HB, Biffi A, McNamara KA, Ayres AM, Valant V, Schwab K, et al: Apolipopro-tein E genotype is associated with CT angiog-raphy spot sign in lobar intracerebral hemorrhage. Stroke 2012; 43:2120-2125.
31. Greenberg CH, Frosch MP, Goldstein JN, Rosand J, Greenberg SM: Modeling intracere-bral hemorrhage growth and response to anticoagulation. PLoS One 2012; 7:e48458.
32. Broderick JP, Diringer MN, Hill MD, Brun NC, Mayer SA, Steiner T, et al: Determinants of intracerebral hemorrhage growth: an exploratory analysis. Stroke 2007; 38:1072-1075.
33. Dowlatshahi D, Smith EE, Flaherty ML, Ali M, Lyden P, Demchuk AM, et al: Small intra-cerebral haemorrhages are associated with less haematoma expansion and better outcomes. Int J Stroke 2011; 6:201-206.
34. Flibotte JJ, Hagan N, O'Donnell J, Greenberg SM, Rosand J: Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology 2004; 63:1059-1064.
35. Cucchiara B, Messe S, Sansing L, Kasner S, Lyden P; CHANT Investigators: Hematoma growth in oral anticoagulant related intrace-rebral hemorrhage. Stroke 2008; 39:2993-2996.
36. Delgado Almandoz JE, Yoo AJ, Stone MJ, Schaefer PW, Oleinik A, Brouwers HB, et al: The spot sign score in primary intracerebral hemorrhage identifies patients at highest risk of in-hospital mortality and poor outcome among survivors. Stroke 2010; 41:54-60.
37. Delcourt C, Huang Y, Arima H, Chalmers J, Davis SM, Heeley EL, et al: Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study. Neurology 2012; 79: 314-319.
38. Diringer MN, Edwards DF: Admission to a neurologic/neurosurgical intensive care unit is associated with reduced mortality rate after intracerebral hemorrhage. Crit Care Med 2001; 29:635-640.
39. Poungvarin N, Bhoopat W, Viriyavejakul A, Rodprasert P, Buranasiri P, Sukondhabhant S, et al: Effects of dexamethasone in primary supratentorial intracerebral hemorrhage. N Engl J Med 1987; 316:1229-1233.
40. Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al: Recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med 2005; 352:777-785.
41. Anderson CS, Huang Y, Wang JG, Arima H, Neal B, Peng B, et al: Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. Lancet Neurol 2008; 7:391-399.
42. Qureshi AI, Palesch YY, Martin R, Novitzke J, Cruz-Flores S, Ehtisham A, et al: Effect of systolic blood pressure reduction on hema-toma expansion, perihematomal edema, and 3-month outcome among patients with intra-cerebral hemorrhage: results from the antihy-pertensive treatment of acute cerebral hemorrhage study. Arch Neurol 2010; 67:570-576.
43. Da Pian R, Bazzan A, Pasqualin A: Surgical versus medical treatment of spontaneous posterior fossa haematomas: a cooperative study on 205 cases. Neurol Res 1984; 6:145-151.
44. van Loon J, Van Calenbergh F, Goffin J, Plets C: Controversies in the management of spontaneous cerebellar haemorrhage. A consecutive series of 49 cases and review of the literature. Acta Neurochir (Wien) 1993; 122:187-193.
45. Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, Hope DT, et al: Early surgery versus initial conservative treatment in patients with spontaneous supraten-torial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet 2005; 365:387-397.
46. Prasad K, Mendelow AD, Gregson B: Surgery for primary supratentorial intracerebral haemorrhage. Cochrane Database Syst Rev 2008; 4:CD000200.
47. Gregson BA, Broderick JP, Auer LM, Batjer H, Chen XC, Juvela S, et al: Individual patient data subgroup meta-analysis of surgery for spontaneous supratentorial intracerebral hemorrhage. Stroke 2012; 43:1496-1504.
48. Mendelow AD, Gregson BA, Mitchell PM, Murray GD, Rowan EN, Gholkar AR, et al: Surgical trial in lobar intracerebral haemorrhage (STICH II) protocol. Trials 2011; 12: 124.
49. Teernstra OP, Evers SM, Lodder J, Leffers P, Franke CL, Blaauw G, et al: Stereotactic treatment of intracerebral hematoma by means of a plasminogen activator: a multicenter randomized controlled trial (SICHPA). Stroke 2003; 34:968-974.
50. Vespa P, McArthur D, Miller C, O'Phelan K, Frazee J, Kidwell C, et al: Frameless stereotac-tic aspiration and thrombolysis of deep intra-cerebral hemorrhage is associated with reduction of hemorrhage volume and neurological improvement. Neurocrit Care 2005; 2:274-281.
51. Newell DW, Shah MM, Wilcox R, Hansmann DR, Melnychuk E, Muschelli J, et al: Minimally invasive evacuation of spontaneous intra-cerebral hemorrhage using sonothromboly-sis. J Neurosurg 2011; 115:592-601.
52. Xi G, Keep RF, Hoff JT: Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol 2006; 5:53-63.
53. Brouwers HB, Goldstein JN, Romero JM, Rosand J: Clinical applications of the computed tomography angiography spot sign in acute intracerebral hemorrhage: a review. Stroke 2012; 43:3427-3432.
54. Selim M, Yeatts S, Goldstein JN, Gomes J, Greenberg S, Morgenstern LB, et al:. Safety and tolerability of deferoxamine mesylate in patients with acute intracerebral hemorrhage. Stroke 2011; 42:3067-307.