Synthesis and characterization of a novel gadolinium-based contrast agent for magnetic resonance imaging of myelination

Journal of Medicinal Chemistry

Volumn 56, Issue 4, 2013, Pages 1629-1640

  Frullano, Luca ^a   Zhu, Junqing ^a   Miller, Robert H ^a   Wang, Yanming ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,2',2' [10 [2 [[3 [4 [[4 [4 (METHYLAMINO)STYRYL] PHENOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]PROPYL]AMINO] 2 OXOETHYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETIC ACID; 2,2',2' [10 [2 [[3 [4 [[4 [4 (METHYLAMINO)STYRYL]PHENOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]PROPYL]AMINO] 2 OXOETHYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL)TRIACETIC ACETATE; CONTRAST MEDIUM; GADOLINIUM; MYELIN; TERT BUTYL METHYL[4 [4 (PROP 2 YN 1 YLOXY)STYRYL]PHENYL]CARBAMATE; TERT BUTYL[4 [(DIETHOXYPHOSPHORYL)METHYL]PHENYL](METHYL)CARBAMATE; TERT BUTYL[4 [4 [[1 (3 AMINOPROPYL) 1H 1,2,3 TRIAZOL 4 YL]METHOXY]STYRYL]PHENYL]METHYLCARBAMATE; TRI TERT BUTYL 2,2',2' [10 [2 [[3 [4 [[4 [4 [(TERT BUTOXYCARBONYL)(METHYL)AMINO]STYRYL]PHENOXY]METHYL] 1H 1,2,3 TRIAZOL 1 YL]PROPYL]AMINO] 2 OXOETHYL] 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7 TRIYL]TRIACETATE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; IN VIVO STUDY; MULTIPLE SCLEROSIS; MYELINATION; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING;

EID: 84874584796     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301435z     Document Type: Article

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