Improved tretinoin photostability in a topical nanomedicine replacing original liquid suspension with spray-dried powder with no loss of effectiveness

Drug Development and Industrial Pharmacy

Volumn 39, Issue 4, 2013, Pages 579-586

  Marchiori, M C L ^a   Rascovetzki, R H ^a   Ourique, A F ^b   Rigo, L A ^a   Silva, C B ^a   Beck, R C R ^b  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Hydrogels; Nanocapsules; Photostability; Spray drying; Tretinoin

Indexed keywords

NANOCAPSULE; RETINOIC ACID;

AQUEOUS SOLUTION; ARTICLE; DISPERSION; DRUG EFFICACY; DRUG FORMULATION; DRUG HALF LIFE; DRUG STABILITY; DRY POWDER; FEASIBILITY STUDY; HYDROGEL; NANOENCAPSULATION; NANOMEDICINE; PHOTODEGRADATION; PHOTOSTABILITY; PHYSICAL CHEMISTRY; SHEAR RATE; SPRAY DRYING; SUSPENSION;

ADMINISTRATION, TOPICAL; ANTINEOPLASTIC AGENTS; CHEMISTRY, PHARMACEUTICAL; DESICCATION; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; HALF-LIFE; NANOMEDICINE; NANOSPHERES; PARTICLE SIZE; PHOTOLYSIS; POLYMERS; POWDERS; SUSPENSIONS; TECHNOLOGY, PHARMACEUTICAL; TRETINOIN; ULTRAVIOLET RAYS;

EID: 84874493430     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2012.691510     Document Type: Article

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