Tretinoin-loaded nanocapsules: Preparation, physicochemical characterization, and photostability study

International Journal of Pharmaceutics

Volumn 352, Issue 1-2, 2008, Pages 1-4

  Ourique, A F ^a   Pohlmann, A R ^b   Guterres, S S ^b   Beck, R C R ^c  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c Centro de Ciencias da Sau   (Brazil)

Author keywords

Nanocapsules; Nanoparticles; Photostability; Retinoic acid; Tretinoin

Indexed keywords

DECANOIC ACID; LACTONE DERIVATIVE; NANOCAPSULE; OCTANOIC ACID; POLYMER EPSILON CAPROLACTONE; RETINOIC ACID; SUNFLOWER OIL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; DRUG FORMULATION; DRUG HALF LIFE; DRUG STABILITY; NANOENCAPSULATION; PHOTODEGRADATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

CAPRYLATES; CHEMISTRY, PHARMACEUTICAL; DECANOIC ACIDS; DERMATOLOGIC AGENTS; DRUG COMPOUNDING; DRUG STABILITY; FEASIBILITY STUDIES; HALF-LIFE; KINETICS; NANOCAPSULES; PARTICLE SIZE; PHOTOLYSIS; PLANT OILS; POLYESTERS; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TRETINOIN; TRIGLYCERIDES; ULTRAVIOLET RAYS;

EID: 39549106682     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.12.035     Document Type: Article

References (29)

1. Alves M.P., Scarrone A.L., Santos M., Pohlmann A.R., and Guterres S.S. Human skin penetration and distribution of nimesulide from hydrophilic gels containing nanocarriers. Int. J. Pharm. 341 (2007) 215-220
2. Beck R.C.R., Pohlmann A.R., Hoffmeister C., Gallas M.R., Collnot E., Schaefer U.F., Guterres S.S., and Lehr C.M. Dexamethasone-loaded nanoparticle-coated microparticles: correlation between in vitro drug release and drug transport across Caco-2 cell monolayers. Eur. J. Pharm. Sci. 67 (2007) 18-30
3. Brisaert M., and Plaizier-Vercammen J. Investigation on the photostability of a tretinoin lotion and stabilization with additives. Int. J. Pharm. 199 (2000) 49-57
4. Brisaert M.G., Everaerts I., and Plaizier-Vercammen J.A. Chemical stability of tretinoin in dermatological preparations. Pharm. Acta Helv. 70 (1995) 161-166
5. Brisaert M.G., Matthis V., and Plaizier-Vercammen J. Liposomes with tretinoin: a physical and chemical evaluation. J. Pharm. Biomed. Anal. 26 (2001) 909-917
6. Corbeil J., Rapaport E., Richman D., and Looney D. Antiproliferative effect of retinoid compounds on Kaposis-sarcoma cells. J. Clin. Invest. 93 (1994) 1981-1986
7. Couvreur P., Barratt G., Fattal E., Legrand P., and Vauthier C. Nanocapsule technology: a review. Crit. Rev. Ther. Drug 19 (2002) 99-134
8. Elbaum D.J. Comparison of the stability of topical isotretinoin and topical tretinoin and their efficacy in acne. J. Am. Acad. Dermatol. 19 (1988) 486-491
9. Ezpeleta I., Irache J.M., Stainmesse S., Chabenat C., Gueguen J., Popineau Y., and Orecchion A.M. Gliadin nanoparticles for the controlled release of all-trans retinoic acid. Int. J. Pharm. 131 (1996) 191-200
10. Fessi, H., Puisieux, F., Devissaguet, J.P., 1988. Procede de préparation dês systèmes coloïdaux d'une substance sous forme de nanocapsules. European Patent 0274961 A1.
11. Guterres S.S., Alves M.P., and Pohlmann A.R. Polymeric nanoparticles, nanospheres and nanocapsules, for cutaneous applications. Drug Target Insights 2 (2007) 147-157
12. Ioele G., Cione E., Risoli A., Genchi G., and Ragno G. Accelerated photostability study of tretinoin and isotretinoin in liposomes formulations. Int. J. Pharm. 293 (2005) 251-260
13. Jeong Y.-I., Kang M.-K., Sun H.-S., Kang S.-S., Kim H.-W., Moon K.-S., Lee K.-J., Kim S.-H., and Jung S. All-trans-retinoic acid release from core-shell type nanoparticles of poly(ε-caprolactone)/poly(ethylene glycol) diblock copolymer. Int. J. Pharm. 273 (2004) 95-107
14. Jimenez M.M., Pelletier J., Bobin M.F., and Martini M.C. Influence of encapsulation on the in vitro percutaneous absorption of octyl methoxycinnamate. Int. J. Pharm. 272 (2004) 45-55
15. Lim S.J., Lee M.K., and Kim C.K. Altered chemical and biological activities of all-trans-retinoic acid incorporated in solid lipid nanoparticle powders. J. Control. Release 100 (2004) 53-61
16. Lin H.S., Chean C.S., Ng Y.Y., Chan S.Y., and Ho P.C. 2-Hydroxypropyl-β-cyclodextrin increases aqueous solubility and photostability of all-trans-retinoic acid. J. Clin. Pharm. Ther. 25 (2000) 265-269
17. Manconi M., Donatella V., Sinico C., Loy G., and Fadda A.M. Niosomes as carriers for tretinoin. Part II. Influence of vesicular incorporation on tretinoin photostability. Int. J. Pharm. 260 (2003) 261-272
18. Montassier P., Duchene D., and Poelman M.C. Inclusion complexes of tretinoin with cyclodextrins. Int. J. Pharm. 153 (1997) 199-209
19. Nam Y.S., Kim K.J., Kang H.S., Park T.G., Han S.-H., and Chang I.S. Chemical immobilization of retinoic acid within poly(epsilon-caprolactone) nanoparticles based on drug-polymer bioconjugates. J. Appl. Polym. Sci. 89 (2003) 1631-1637
20. Perugini P., Simeoni S., Scalia S., Genta I., Modena T., Conti B., and Pavanetto F. Effect of nanoparticle encapsulation on the photostability of the sunscreen agent, 2-ethylhexyl-p-methoxycinnamate. Int. J. Pharm. 246 (2002) 37-45
21. Pohlmann A.R., Weiss V., Mertins O., Pesce da Silveira N., and Guterres S.S. Spray-dried indomethacin-loaded polyester nanocapsules and nanospheres: development, stability evaluation and nanostructure models. Eur. J. Pharm. Sci. 16 (2002) 305-312
22. Polano M.K. Tretinoin in dermatologie. Pharm. Weekblad. 109 (1974) 908-909
23. Rigopoulos D., Ioannides D., Kalogeromitros D., and Katsambas A. Comparison of topical retinoids in the treatment of acne. Clin. Dermatol. 22 (2004) 408-411
24. Sacks P.G., Oke V., and Mehta K. Antiproliferative effects of free and liposome-encapsulated retinoic acid in a squamous carcinoma model: monolayer cells and multicellular tumor spheroids. J. Cancer Res. Clin. Oncol. 118 (1992) 490-496
25. Schaffazick S.R., Freitas L.L., Pohlmann A.R., and Guterres S.S. Caracterização e estabilidade físico-química de sistemas poliméricos nanoparticulados para administração de fármacos. Quim. Nova 25 (2003) 726-737
26. Seo S.-J., Moon H.-S., Guo D.-D., Kim S.-H., Akaike T., and Cho C.-S. Receptor-mediated delivery of all-trans-retinoic acid (ATRA) to hepatocytes from ATRA-loaded poly (N-p-vinylbenzyl-4-o-β-d-galactopyranosyl-d-gluconamide) nanoparticles. Mater. Sci. Eng. A 26 (2006) 136-141
27. Shah, K.A., 2007. Solid lipid nanoparticles (SLN) of tretinoin: potential in topical delivery. Int J. Pharm. doi:10.1016/j.ijpharm.2007.05.061
28. Shimizu K., Tamagawa K., Takahashi N., Takayama K., and Maitani Y. Stability and antitumor effects of all-trans retinoic acid-loaded liposomes contained sterylglucoside mixture. Int. J. Pharm. 258 (2003) 45-53
29. Shin S.C., Kim H.J., Oh I.J., Cho C.W., and Yang K.H. Development of tretinoin gels for enhanced transdermal delivery. Eur. J. Pharm. Biopharm. 60 (2005) 67-71