Hashimoto's Thyroiditis, microcalcification and raised thyrotropin levels within normal range are associated with thyroid cancer

World Journal of Surgical Oncology

Volumn 11, Issue , 2013, Pages

  Ye, Zhi qiang ^a   Gu, Dian na ^a   Hu, Hong ye ^a   Zhou, Yi li ^a   Hu, Xiao qu ^a   Zhang, Xiao hua ^a  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Papillary thyroid cancer; Thyroid cancer; Thyroiditis; Thyrotropin

Indexed keywords

MICROSOME ANTIBODY; THYROGLOBULIN; THYROGLOBULIN ANTIBODY; THYROTROPIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CALCIFICATION; CANCER INFILTRATION; CANCER PATIENT; CANCER RISK; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; HASHIMOTO DISEASE; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PREDICTION; RISK ASSESSMENT; SCHOOL CHILD; THYROGLOBULIN BLOOD LEVEL; THYROID CANCER; THYROID PAPILLARY CARCINOMA; THYROIDECTOMY; THYROTROPIN BLOOD LEVEL; TUMOR INVASION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CALCINOSIS; CARCINOMA, PAPILLARY; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; HASHIMOTO DISEASE; HUMANS; INFANT; INFANT, NEWBORN; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; THYROID NEOPLASMS; THYROTROPIN; YOUNG ADULT;

EID: 84874460276     PISSN: None     EISSN: 14777819     Source Type: Journal    
DOI: 10.1186/1477-7819-11-56     Document Type: Article

References (51)

1. Sherman SI. Thyroid carcinoma. Lancet 2003, 361:501-511. 10.1016/S0140-6736(03)12488-9, 12583960.
2. Zheng W, Zhang Z. An analysis of cancer incidence in 2005 in Lucheng District, Wenzhou City, Zhejiang Province. Bulletin of Chinese Cancer 2007, 16:306-308.
3. Marqusee E, Benson CB, Frates MC, Doubilet PM, Larsen PR, Cibas ES, Mandel SJ. Usefulness of ultrasonography in the management of nodular thyroid disease. Ann Intern Med 2000, 133:696-700. 10.7326/0003-4819-133-9-200011070-00011, 11074902.
4. Shibata Y, Yamashita S, Masyakin VB, Panasyuk GD, Nagataki S. 15 years after Chernobyl: new evidence of thyroid cancer. Lancet 2001, 358:1965-1966. 10.1016/S0140-6736(01)06971-9, 11747925.
5. Hegedus L, Bonnema SJ, Bennedbaek FN. Management of simple nodular goiter: current status and future perspectives. Endocr Rev 2003, 24:102-132. 10.1210/er.2002-0016, 12588812.
6. Yeung MJ, Serpell JW. Management of the solitary thyroid nodule. Oncologist 2008, 13:105-112. 10.1634/theoncologist.2007-0212, 18305054.
7. Christensen SB, Bondeson L, Ericsson UB, Lindholm K. Prediction of malignancy in the solitary thyroid nodule by physical examination, thyroid scan, fine-needle biopsy and serum thyroglobulin. A prospective study of 100 surgically treated patients. Acta Chir Scand 1984, 150:433-439.
8. Stocker DJ, Burch HB. Thyroid cancer yield in patients with Graves' disease. Minerva Endocrinol 2003, 28:205-212.
9. Boelaert K, Horacek J, Holder RL, Watkinson JC, Sheppard MC, Franklyn JA. Serum thyrotropin concentration as a novel predictor of malignancy in thyroid nodules investigated by fine-needle aspiration. J Clin Endocrinol Metab 2006, 91:4295-4301. 10.1210/jc.2006-0527, 16868053.
10. Haymart MR, Repplinger DJ, Leverson GE, Elson DF, Sippel RS, Jaume JC, Chen H. Higher serum thyroid stimulating hormone level in thyroid nodule patients is associated with greater risks of differentiated thyroid cancer and advanced tumor stage. J Clin Endocrinol Metab 2008, 93:809-814. 2266959, 18160464.
11. Cipolla C, Sandonato L, Graceffa G, Fricano S, Torcivia A, Vieni S, Latteri S, Latteri MA. Hashimoto thyroiditis coexistent with papillary thyroid carcinoma. Am Surg 2005, 71:874-878.
12. Dailey ME, Lindsay S, Skahen R. Relation of thyroid neoplasms to Hashimoto disease of the thyroid gland. AMA 1955, 70:291-297.
13. Crile G. Struma lymphomatosa and carcinoma of the thyroid. Surg Gynecol Obstet 1978, 147:350-352.
14. Crile G, Hazard JB. Incidence of cancer in struma lymphomatosa. Surg Gynecol Obstet 1962, 115:101-103.
15. Holm LE, Blomgren H, Lowhagen T. Cancer risks in patients with chronic lymphocytic thyroiditis. N Eng J Med 1985, 312:601-604.
16. Ott RA, McCall AR, McHenry C, Jarosz H, Armin A, Lawrence AM, Paloyan E. The incidence of thyroid carcinoma in Hashimoto's thyroiditis. Am Surg 1987, 53:442-445.
17. Shands WC. Carcinoma of the thyroid in association with struma lymphomatosa (Hashimoto's disease). Ann Surg 1960, 151:675-682. 10.1097/00000658-196005000-00008, 1613703, 14445445.
18. Singh B, Shaha AR, Trivedi H, Carew JF, Poluri A, Shah JP. Coexistent Hashimoto's thyroiditis with papillary thyroid carcinoma: impact on presentation, management, and outcome. Surgery 1999, 126:1070-1076. discussion 1076-1077, 10.1067/msy.2099.101431, 10598190.
19. Fiore E, Rago T, Latrofa F, Provenzale MA, Piaggi P, Delitala A, Scutari M, Basolo F, Di Coscio G, Grasso L, et al. Hashimoto's thyroiditis is associated with papillary thyroid carcinoma: role of TSH and of treatment with L-thyroxine. Endocr Relat Cancer 2011, 18:429-437. 10.1530/ERC-11-0028, 21565972.
20. Larson SD, Jackson LN, Riall TS, Uchida T, Thomas RP, Qiu S, Evers BM. Increased incidence of well-differentiated thyroid cancer associated with Hashimoto thyroiditis and the role of the PI3k/Akt pathway. J Am Coll Surg 2007, 204:764-773. discussion 773-765, 10.1016/j.jamcollsurg.2006.12.037, 2430882, 17481480.
21. Robbins KT, Shaha AR, Medina JE, Califano JA, Wolf GT, Ferlito A, Som PM, Day TA. Consensus statement on the classification and terminology of neck dissection. Arch Otolaryngol Head Neck Surg 2008, 134:536-538. 10.1001/archotol.134.5.536, 18490577.
22. Hegedus L. Clinical practice. The thyroid nodule. N Eng J Med 2004, 351:1764-1771.
23. Mazzaferri EL. Management of a solitary thyroid nodule. N Eng J Med 1993, 328:553-559.
24. Polyzos SA, Kita M, Efstathiadou Z, Poulakos P, Slavakis A, Sofianou D, Flaris N, Leontsini M, Kourtis A, Avramidis A. Serum thyrotropin concentration as a biochemical predictor of thyroid malignancy in patients presenting with thyroid nodules. J Cancer Res Clin Oncol 2008, 134:953-960. 10.1007/s00432-008-0373-7, 18327610.
25. Jonklaas J, Nsouli-Maktabi H, Soldin SJ. Endogenous thyrotropin and triiodothyronine concentrations in individuals with thyroid cancer. Thyroid 2008, 18:943-952. 10.1089/thy.2008.0061, 2879493, 18788918.
26. Gharib H. Changing trends in thyroid practice: understanding nodular thyroid disease. Endocr Pract 2004, 10:31-39.
27. Papini E, Petrucci L, Guglielmi R, Panunzi C, Rinaldi R, Bacci V, Crescenzi A, Nardi F, Fabbrini R, Pacella CM. Long-term changes in nodular goiter: a 5-year prospective randomized trial of levothyroxine suppressive therapy for benign cold thyroid nodules. J Clin Endocrinol Metab 1998, 83:780-783. 10.1210/jc.83.3.780, 9506726.
28. Vermiglio F, Lo Presti VP, Violi MA, Moleti M, Castagna MG, Finocchiaro MD, Mattina F, Mandolfino M, Zimbaro G, Trimarchi F. Changes in both size and cytological features of thyroid nodule after levothyroxine treatment. Clin Endocrinol 2003, 59:347-353.
29. Zelmanovitz F, Genro S, Gross JL. Suppressive therapy with levothyroxine for solitary thyroid nodules: a double-blind controlled clinical study and cumulative meta-analyses. J Clin Endocrinol Metab 1998, 83:3881-3885. 10.1210/jc.83.11.3881, 9814462.
30. Fiore E, Rago T, Provenzale MA, Scutari M, Ugolini C, Basolo F, Di Coscio G, Miccoli P, Grasso L, Pinchera A, Vitti P. L-thyroxine-treated patients with nodular goiter have lower serum TSH and lower frequency of papillary thyroid cancer: results of a cross-sectional study on 27 914 patients. Endocr Relat Cancer 2010, 17:231-239. 10.1677/ERC-09-0251, 20167722.
31. Matsuo K, Friedman E, Gejman PV, Fagin JA. The thyrotropin receptor (TSH-R) is not an oncogene for thyroid tumors: structural studies of the TSH-R and the alpha-subunit of Gs in human thyroid neoplasms. J Clin Endocrinol Metab 1993, 76:1446-1451. 10.1210/jc.76.6.1446, 8501149.
32. Derwahl M, Broecker M, Kraiem Z. Clinical review 101: Thyrotropin may not be the dominant growth factor in benign and malignant thyroid tumors. J Clin Endocrinol Metab 1999, 84:829-834. 10.1210/jc.84.3.829, 10084556.
33. Mazzaferri EL. Thyroid cancer and Graves' disease: the controversy ten years later. Endocr Pract 2000, 6:221-225. 10.4158/EP.6.2.221, 11421537.
34. Kimura T, Van Keymeulen A, Golstein J, Fusco A, Dumont JE, Roger PP. Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models. Endocr Rev 2001, 22:631-656. 10.1210/er.22.5.631, 11588145.
35. Shi Y, Zou M, Farid NR. Expression of thyrotrophin receptor gene in thyroid carcinoma is associated with a good prognosis. Clin Endocrinol 1993, 39:269-274.
36. Satta MA, De Rosa G, Testa A, Maussier ML, Valenza V, Rabitti C, Saletnich I, D'Ugo D, Picciocchi A. Thyroid cancer in suppressed contralateral lobe of patients with hot thyroid nodule. Eur J Cancer 1993, 29A:1190-1192.
37. Gudmundsson J, Sulem P, Gudbjartsson DF, Jonasson JG, Sigurdsson A, Bergthorsson JT, He H, Blondal T, Geller F, Jakobsdottir M, et al. Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat Genet 2009, 41:460-464. 10.1038/ng.339, 3664837, 19198613.
38. Spencer CA. Serum thyroglobulin measurements: clinical utility and technical limitations in the management of patients with differentiated thyroid carcinomas. Endocr Pract 2000, 6:481-484.
39. Hegedus L. Thyroid ultrasound. Endocrinol Metab Clin North Am 2001, 30:339-360. viii-ix, 10.1016/S0889-8529(05)70190-0, 11444166.
40. Franklyn JA, Daykin J, Young J, Oates GD, Sheppard MC. Fine needle aspiration cytology in diffuse or multinodular goitre compared with solitary thyroid nodules. BMJ 1993, 307:240. 10.1136/bmj.307.6898.240, 1678158, 8369686.
41. Mazzaferri EL, Santos ET D, Rofagha-Keyhani S. Solitary thyroid nodule: diagnosis and management. MCNA 1988, 72:1177-1211.
42. Frates MC, Benson CB, Doubilet PM, Kunreuther E, Contreras M, Cibas ES, Orcutt J, Moore FD, Larsen PR, Marqusee E, Alexander EK. Prevalence and distribution of carcinoma in patients with solitary and multiple thyroid nodules on sonography. J Clin Endocrinol Metab 2006, 91:3411-3417. 10.1210/jc.2006-0690, 16835280.
43. Wang N, Xu Y, Ge C, Guo R, Guo K. Association of sonographically detected calcification with thyroid carcinoma. Head Neck 2006, 28:1077-1083. 10.1002/hed.20481, 17022090.
44. Okayasu I, Fujiwara M, Hara Y, Tanaka Y, Rose NR. Association of chronic lymphocytic thyroiditis and thyroid papillary carcinoma. A study of surgical cases among Japanese, and white and African Americans. Cancer 1995, 76:2312-2318. 10.1002/1097-0142(19951201)76:11<2312::AID-CNCR2820761120>3.0.CO;2-H, 8635037.
45. Harach HR, Ceballos GA. Thyroid cancer, thyroiditis and dietary iodine: a review based on the Salta, Argentina model. Endocr Pathol 2008, 19:209-220. 10.1007/s12022-008-9038-y, 18696273.
46. Kang DY, Kim KH, Kim JM, Kim SH, Kim JY, Baik HW, Kim YS. High prevalence of RET, RAS, and ERK expression in Hashimoto's thyroiditis and in papillary thyroid carcinoma in the Korean population. Thyroid 2007, 17:1031-1038. 10.1089/thy.2007.0035, 17900235.
47. Kashima K, Yokoyama S, Noguchi S, Murakami N, Yamashita H, Watanabe S, Uchino S, Toda M, Sasaki A, Daa T, Nakayama I. Chronic thyroiditis as a favorable prognostic factor in papillary thyroid carcinoma. Thyroid 1998, 8:197-202. 10.1089/thy.1998.8.197, 9545105.
48. Loh KC, Greenspan FS, Dong F, Miller TR, Yeo PP. Influence of lymphocytic thyroiditis on the prognostic outcome of patients with papillary thyroid carcinoma. J Clin Endocrinol Metab 1999, 84:458-463. 10.1210/jc.84.2.458, 10022401.
49. Matsubayashi S, Kawai K, Matsumoto Y, Mukuta T, Morita T, Hirai K, Matsuzuka F, Kakudoh K, Kuma K, Tamai H. The correlation between papillary thyroid carcinoma and lymphocytic infiltration in the thyroid gland. J Clin Endocrinol Metab 1995, 80:3421-3424. 10.1210/jc.80.12.3421, 8530576.
50. Del Rio P, Cataldo S, Sommaruga L, Concione L, Arcuri MF, Sianesi M. The association between papillary carcinoma and chronic lymphocytic thyroiditis: does it modify the prognosis of cancer?. Minerva Endocrinol 2008, 33:1-5.
51. Kim KW, Park YJ, Kim EH, Park SY, Park Do J, Ahn SH, Jang HC, Cho BY. Elevated risk of papillary thyroid cancer in Korean patients with Hashimoto's thyroiditis. Head Neck 2011, 33:691-695. 10.1002/hed.21518, 21484918.