Hashimoto's thyroiditis is associated with papillary thyroid carcinoma: Role of TSH and of treatment with L-thyroxine

Endocrine-Related Cancer

Volumn 18, Issue 4, 2011, Pages 429-437

  Fiore, E ^a   Rago, T ^a   Latrofa, F ^a   Provenzale, M A ^a   Piaggi, P ^a   Delitala, A ^a   Scutari, M ^a   Basolo, F ^a   Di Coscio, G ^a   Grasso, L ^a   Pinchera, A ^a   Vitti, P ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOTHYROXINE; LIOTHYRONINE; THYROGLOBULIN ANTIBODY; THYROID ANTIBODY; THYROID PEROXIDASE ANTIBODY; THYROTROPIN; THYROXINE;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HASHIMOTO DISEASE; HUMAN; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; MALE; NODULAR GOITER; THYROID PAPILLARY CARCINOMA; THYROTROPIN BLOOD LEVEL;

ADULT; AUTOANTIBODIES; CARCINOMA, PAPILLARY; FEMALE; GOITER, NODULAR; HASHIMOTO DISEASE; HUMANS; HYPOTHYROIDISM; MALE; PROGNOSIS; THYROID NEOPLASMS; THYROIDITIS, AUTOIMMUNE; THYROTROPIN; THYROXINE;

EID: 79960839823     PISSN: 13510088     EISSN: 14796821     Source Type: Journal    
DOI: 10.1530/ERC-11-0028     Document Type: Article

References (35)

1. Anil C, Goksel S & Gursoy A 2010 Hashimoto's thyroiditis is not associated with increased risk of thyroid cancer in patients with thyroid nodules: a single-center prospective study. Thyroid 20 601-606. (doi:10.1089/thy.2009.0450)
2. Baker JR Jr 1995 The immune response to papillary thyroid cancer. Journal of Clinical Endocrinology and Metabolism 80 3419-3420. (doi:10.1210/jc.80.12. 3419)
3. Boelaert K, Horacek J, Holder RL, Watkinson JC, Sheppard MC & Franklyn JA 2006 Serum thyrotropin concentration as a novel predictor of malignancy in thyroid nodules investigated by fine-needle aspiration. Journal of Clinical Endocrinology and Metabolism 91 4295-4301. (doi:10.1210/jc.2006-0527)
4. British Thyroid Association 2007 Fine-needle aspiration cytology. In Report of the thyroid cancer guidelines update group, 2nd edn, pp 9-10. London, UK: Royal College of Physicians.
5. Ciampi R & Nikiforov YE 2007 RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis. Endocrinology 148 936-941. (doi:10.1210/en.2006-0921)
6. Dailey ME, Lindsay S & Skahen R 1955 Relation of thyroid neoplasms to Hashimoto disease of the thyroid gland. A.M.A. Archives of Surgery 70 291-297.
7. Fiore E, Rago T, Provenzale MA, Scutari M, Ugolini C, Basolo F, Di Coscio G, Berti P, Grasso L, Elisei R et al. 2009a Lower levels of TSH are associated with a lower risk of papillary thyroid cancer in patients with thyroid nodular disease: thyroid autonomy may play a protective role. Endocrine-Related Cancer 16 1251-1260. (doi:10.1677/ERC-09-0036)
8. Fiore E, Rago T, Scutari M, Ugolini C, Proietti A, Di Coscio G, Provenzale MA, Berti P, Grasso L, Mariotti S et al. 2009b Papillary thyroid cancer, although strongly associated with lymphocytic infiltration on histology, is only weakly predicted by serum thyroid auto-antibodies in patients with nodular thyroid diseases. Journal of Endocrinological Investigation 32 344-351.
9. Fiore E, Rago T, Provenzale MA, Scutari M, Ugolini C, Basolo F, Di Coscio G, Miccoli P, Grasso L, Pinchera A et al. 2010 L-thyroxine-treated patients with nodular goiter have lower serum TSH and lower frequency of papillary thyroid cancer: results of a cross-sectional study on 27 914 patients. Endocrine-Related Cancer 17 231-239. (doi:10.1677/ERC-09-0251)
10. Franco AT, Malaguarnera R, Refetoff S, Liao XH, Lundsmith E, Kimura S, Pritchard C, Marais R, Davies TF, Weinstein LS et al. 2011 Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. PNAS 108 1615-1620. (doi:10.1073/pnas.1015557108)
11. Haymart MR, Glinberg SL, Liu J, Sippel RS, Jaume JC &Chen H 2008a Higher serum TSH in thyroid cancer patients occurs independent of age and correlates with extrathyroidal extension. Clinical Endocrinology 71 434-439. (doi:10.1111/j.1365-2265.2008.03489.x)
12. Haymart MR, Repplinger DJ, Leverson GE, Elson DF, Sippel RS, Jaume JC & Chen H 2008b Higher serum thyroid stimulating hormone level in thyroid nodule patients is associated with greater risks of differentiated thyroid cancer and advanced tumor stage. Journal of Clinical Endocrinology and Metabolism 93 809-814. (doi:10.1210/jc.2007-2215)
13. Hirabayashi RN & Lindsay S 1965 The relation of thyroid carcinoma and chronic thyroiditis. Surgery, Gynecology & Obstetrics 121 243-252.
14. Hollowell JG, Staehling NW, Flanders WD, Hannon WH, GunterEW, SpencerCA&BravermanLE2002 SerumTSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). Journal of Clinical Endocrinology and Metabolism 87 489-499. (doi:10.1210/jc.87.2.489)
15. Holm LE, Blomgren H & Lowhagen T 1985 Cancer risks in patients with chronic lymphocytic thyroiditis. New England Journal of Medicine 312 601-604. (doi:10.1056/NEJM198503073121001)
16. Jin J, Machekano R & McHenry CR 2010 The utility of preoperative serum thyroid-stimulating hormone level for predicting malignant nodular thyroid disease. American Journal of Surgery 199 294-297. (doi:10.1016/j.amjsurg.2009. 08.028)
17. Jonklaas J, Nsouli-Maktabi H & Soldin SJ 2008 Endogenous thyrotropin and triiodothyronine concentrations in individuals with thyroid cancer. Thyroid 18 943-952. (doi:10.1089/thy.2008.0061)
18. Kim ES, Lim DJ, Baek KH, Lee JM, Kim MK, Kwon HS, Song KH, Kang MI, Cha BY, Lee KW et al. 2010 Thyroglobulin antibody is associated with increased cancer risk in thyroid nodules. Thyroid 20 885-891. (doi:10.1089/thy.2009.0384)
19. Knobel M, Barca MF, Pedrinola F & Medeiros-Neto G 1994 Prevalence of anti-thyroid peroxidase antibodies in autoimmune and nonautoimmune thyroid disorders in a relatively low-iodine environment. Journal of Endocrinological Investigation 17 837-842.
20. Latrofa F, Ricci D, Grasso L, Vitti P, Masserini L, Basolo F, Ugolini C, Mascia G, Lucacchini A & Pinchera A 2008 Characterization of thyroglobulin epitopes in patients with autoimmune and non-autoimmune thyroid diseases using recombinant human monoclonal thyroglobulin autoantibodies. Journal of Clinical Endocrinology and Metabolism 93 591-596. (doi:10.1210/jc.2007-1199)
21. Marcocci C, Vitti P, Cetani F, Catalano F, Concetti R &Pinchera A 1991 Thyroid ultrasonography helps to identify patients with diffuse lymphocytic thyroiditis who are prone to develop hypothyroidism. Journal of Clinical Endocrinology and Metabolism 72 209-213. (doi:10.1210/jcem-72-1-209)
22. Mariotti S, Caturegli P, Piccolo P, Barbesino G & Pinchera A 1990 Antithyroid peroxidase autoantibodies in thyroid diseases. Journal of Clinical Endocrinology and Metabolism 71 661-669. (doi:10.1210/jcem-71-3-661)
23. Mechler C, Bounacer A, Suarez H, Saint FM, Magois C, Aillet G & Gaulier A 2001 Papillary thyroid carcinoma: 6 cases from 2 families with associated lymphocytic thyroiditis harbouring RET/PTC rearrangements. British Journal of Cancer 85 1831-1837. (doi:10.1054/bjoc.2001.2187)
24. Nikiforov YE 2006 RET/PTC rearrangement - a link between Hashimoto's thyroiditis and thyroid cancer.or not. Journal of Clinical Endocrinology and Metabolism 91 2040-2042. (doi:10.1210/jc.2006-0791)
25. Nikiforova MN & Nikiforov YE 2008 Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis. Expert Review of Molecular Diagnostics 8 83-95. (doi:10.1586/14737159.8.1.83)
26. Okayasu I 1997 The relationship of lymphocytic thyroiditis to the development of thyroid carcinoma. Endocrine Pathology 8 225-230. (doi:10.1007/BF02738789)
27. Okayasu I, Fujiwara M, Hara Y, Tanaka Y & Rose NR 1995 Association of chronic lymphocytic thyroiditis and thyroid papillary carcinoma. A study of surgical cases among Japanese, andwhite andAfricanAmericans. Cancer 76 2312-2318. (doi:10.1002/1097-0142(19951201) 76:11〈2312::AID- CNCR2820761120〉3.0.CO;2-H)
28. Polyzos SA, Kappaita M, Efstathiadou Z, Poulakos P, Slavakis A, Sofianou D, Flaris N, Leontsini M, Kourtis A & Avramidis A 2008 Serum thyrotropin concentration as a biochemical predictor of thyroid malignancy in patients presenting with thyroid nodules. Journal of Cancer Research and Clinical Oncology 134 953-960. (doi:10.1007/s00432-008-0373-7)
29. Rago T, Fiore E, Scutari M, Santini F, Di Coscio G, Romani R, Piaggi P, Ugolini C, Basolo F, Miccoli P et al. 2010 Male sex, single nodularity, and young age are associated with the risk of finding a papillary thyroid cancer on fine-needle aspiration cytology in a large series of patients with nodular thyroid disease. European Journal of Endocrinology 162 763-770. (doi:10.1530/EJE-09-0895)
30. Rhoden KJ, Unger K, Salvatore G, Yilmaz Y, Vovk V, Chiappetta G, Qumsiyeh MB, Rothstein JL, Fusco A, Santoro M et al. 2006 RET/papillary thyroid cancer rearrangement in non neoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma. Journal of Clinical Endocrinology and Metabolism 91 2414-2423. (doi:10.1210/jc.2006-0240)
31. Singh B, Shaha AR, Trivedi H, Carew JF, Poluri A & Shah JP 1999 Coexistent Hashimoto's thyroiditis with papillary thyroid carcinoma: impact on presentation, management, and outcome. Surgery 126 1070-1076. (doi:10.1067/msy.2099.101431)
32. The Papanicolaou Society of Cytopathology Task Force on Standards of Practice 1996 Guidelines of the Papanicolaou Society of Cytopathology for the examination of fine-needle aspiration specimens from thyroid nodules. Diagnostic Cytopathology 15 84-89. (doi:10.1002/(SICI)1097-0339(199607)15:1〈84::AID- DC18〉3.0.CO;2-8)
33. Vanderpump MP, Tunbridge WM, French JM, Appleton D, Bates D, Clark F, Grimley EJ, Hasan DM, Rodgers H, Tunbridge F et al. 1995 The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clinical Endocrinology 43 55-68. (doi:10.1111/j.1365-2265.1995.tb01894. x)
34. Vejbjerg P, Knudsen N, Perrild H, Laurberg P, Pedersen IB, Rasmussen LB, Ovesen L & Jorgensen T 2006 The association between hypoechogenicity or irregular echo pattern at thyroid ultrasonography and thyroid function in the general population. European Journal of Endocrinology 155 547-552. (doi:10.1530/eje.1.02255)
35. Walsh JP, Bremner AP, Feddema P, Leedman PJ, Brown SJ & O'Leary P 2010 Thyrotropin and thyroid antibodies as predictors of hypothyroidism: a 13-year, longitudinal study of a community-based cohort using current immunoassay techniques. Journal of Clinical Endocrinology and Metabolism 95 1095-1104. (doi:10.1210/jc.2009-1977)