Hepatoprotective activity of Cyperus articulatus Linn. against paracetamol induced hepatotoxicity in rats

Journal of Chemical and Pharmaceutical Research

Volumn 5, Issue 1, 2013, Pages 314-319

  Datta, Samaresh ^a   Dhar, Susmita ^b   Nayak, S S ^c   Dinda, Subas Chandra ^d  

^a AND College of Pharmacy   (India)

^b AL AMEEN COLLEGE OF PHARMACY   (India)

^c Department of Pharmaceutics   (India)

^d BERHAMPUR UNIVERSITY   (India)

Author keywords

Antioxidant; Cyperus articulatus; Hepatoprotective; Paracetamol; Silymarin

Indexed keywords

ANTIOXIDANT ASSAYS; ANTIOXIDANT STATUS; BIOCHEMICAL PARAMETERS; CARBOXY-METHYL CELLULOSE; CATALASE ACTIVITY; CYPERACEAE; CYPERUS ARTICULATUS; HEPATOPROTECTIVE; HEPATOPROTECTIVE ACTIVITIES; HEPATOTOXICITY; LIPID PEROXIDATION; LIVER DAMAGE; LIVER FUNCTIONS; LIVER TISSUE; MEDICINAL PLANTS; METHANOL EXTRACT; ORAL ADMINISTRATION; PARACETAMOL; REDUCED GLUTATHIONE; SILYMARIN; SUPER OXIDE DISMUTASE; TOTAL PROTEIN; TOXIC EFFECT; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; FLAVONOIDS; METHANOL; OXYGEN; PLANT EXTRACTS; PROTEINS; TISSUE;

RATS;

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CATALASE; CYPERUS ARTICULATUS EXTRACT; GLUTATHIONE; LIVER PROTECTIVE AGENT; METHANOL; PARACETAMOL; PLANT EXTRACT; SILYMARIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; CYPERUS; CYPERUS ARTICULATUS; ENZYME ACTIVITY; FATTY LIVER; FEMALE; HISTOPATHOLOGY; LD 50; LIPID PEROXIDATION; LIVER HOMOGENATE; LIVER NECROSIS; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; RAT;

EID: 84874444615     PISSN: None     EISSN: 09757384     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. RK Patel; MM Patel; MP Patel; NR Kanzaria; KR Vaghela; NJ Patel, Phcog mag., 2008, 4, 118-23.
2. FV DeFeuids; V Papadopoulos; K Drieu, Fundam Clin Pharamacol., 2003, 17, 405-17.
3. AH Banskota; Y Tezuka; IK Adnyana; Q Xiong; K Hase; KQ Tran, Biol Pharm Bull., 23, 2000, 456-60.
4. GR Takeoka; LT Dao, J. Agri Food Chem., 2003, 51, 496-501.
5. EN Bum; A Rakotonirina; SV Rakotonirina; P Herrling, J. Ethnopharmacol., 2003, 87, 27-34.
6. VS Rakotonirina; EN Bum; A Rakotonirina; M Bopelet, Fitoterapia; 2001, 72, 22-29.
7. H Ohshima; Y Yoshie; S Auriol; I Gilibert, Free Rad Bio & Medicine, 1998, 25(9), 1057-65.
8. DJ Jollow; SS Thorgeirsson; WZ Potter; M Hashimoto; JR Mitchell, Pharmacology, 1974, 12, 251-71.
9. LT Wong; LW Whitehouse; G Solemonraj; CJ Paul, Toxicity Lett., 1981, 9, 145-51.
10. MC Savides; FW Oehne, J. App Toxicol., 1983, 3, 95-111.
11. NPE Vermeulen; JGM Bessems; RV Streat, Drug Metab Rev., 1992, 24, 367-407.
12. M Moore; H Thor; G Moore; S Nelson; P Moldeus; S Correnius, J. Biol Chem., 1985, 260, 13035-40.
13. H Ohkawa; N Onishi; K Yagi, Anal Biochem., 1979, 95, 351-58.
14. GL Ellman, Arch Biochem Biophys., 1959, 82, 70-77.
15. P Kakkar; B Das; PN Vishwanath, Indian J. Biochem Biophys., 1984, 21, 130-32.
16. H Aebi, L Packer. Methods in Enzymatic Analysis, Vol. II, Academic Press, New York, 1974, 673-84.
17. PB Watkins; LB Seef, Hepatology, 2006, 43, 618-31.
18. EM Boyd; GM Bereczky, Br J. Pharmacol., 1966, 26, 606-14.
19. SK Mitra; MV Venkataranganna; R Sudaram; S Gopumadhavan, J. Ethnopharmacol., 1998, 63, 181-86.
20. th Edition, Williams and Wilkins, Baltimore, 1984, 101-07.
21. RO Recknagel; EA Glende; JA Jr Dolak; RL Walter, Pharmacol Ther., 1989, 43, 139-54.
22. MR Venukumar; MS Latha, Indian J. Clin Biochem., 2002, 17(2), 80-87.
23. AK Shenoy; SN Somayaji; KL Bairy, Indian J. Pharmacol., 2001, 33, 260-66.
24. OECD. Guidelines for the Testing of Chemicals/Section 4: Health Effects Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure. Paris, Organisation for Economic Co-operation and Development Publishing, 2008.