Static magnetic field of 6 mT induces apoptosis and alters cell cycle in p53 mutant Jurkat cells

Electromagnetic Biology and Medicine

Volumn 32, Issue 1, 2013, Pages 9-19

  Ahmadianpour, Mohammad Reza ^a   Abdolmaleki, Parviz ^a   Mowla, Seyed Javad ^a   Hosseinkhani, Saman ^a  

^a TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Apoptosis; Cell cycle; Jurkat Cell; Luminescence; Static Magnetic Field

Indexed keywords

AFTER-TREATMENT; APOPTOSIS INDUCTION; APOPTOSIS RATES; CELL CYCLE; CELL POPULATIONS; CELLULAR POPULATIONS; EFFECT OF MAGNETIC FIELD; FLOW-CYTOMETRIC ANALYSIS; JURKAT CELL; LUMINESCENCE DETECTION; P53 MUTANTS; RADICAL FORMATION; SIGNIFICANT DIFFERENCES; STATIC MAGNETIC FIELDS; WESTERN-BLOT ANALYSIS;

CELL CULTURE; CELL MEMBRANES; CELL PROLIFERATION; FREE RADICALS; INTERNET PROTOCOLS; LUMINESCENCE; MAGNETIC FIELDS; PHOSPHORYLATION; PROTEINS;

CELL DEATH;

ATM PROTEIN; E2F1 PROTEIN, HUMAN; PROTEIN P53; TRANSCRIPTION FACTOR E2F1;

APOPTOSIS; ARTICLE; CELL CYCLE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LEUKEMIA CELL LINE; MAGNETIC FIELD; METABOLISM; MUTATION; PHOSPHORYLATION; TIME; JURKAT CELL LINE;

APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL CYCLE; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HUMANS; JURKAT CELLS; MAGNETIC FIELDS; MUTATION; PHOSPHORYLATION; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84874386314     PISSN: 15368378     EISSN: 15368386     Source Type: Journal    
DOI: 10.3109/15368378.2012.692748     Document Type: Article

References (31)

1. Aldinucci, C., Garcia, J. B., Palmi, M., et al. (2003). The effect of strong static magnetic field on lymphocytes. Bioelectromagnetics 24:109-117.
2. Anderson, L. V. B. (1996). Optimised protein diagnosis in the autosomal recessive limb-girdle muscular dystrophies. Neuromusc. Disord. 6:443-446.
3. Bakkenist, C., Kastan, M. B. (2003). DNA damage activates ATM through intermolecular auto-phosphorylation and dimmer dissociation. Nature 421:499-506.
4. Bian, X., Hughes, F. M. Jr., Huang, Y., et al. (1997). Roles of cytoplasmic Ca2 and intracellular Ca2 stores in induction and suppression of apoptosis in S49 cells. Amer. J. Phys. 272:1241-1249.
5. Brune, B. (2003). Nitric oxide: NO apoptosis or turning it ON? Cell Death Diff. 10:864-869.
6. Canman, C. E., Lim, D. S., Cimprich, K. A., et al. (1998). Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281:1677-1679.
7. Chionna, A., Dwikat, M., Panzarini, E., et al. (2003). Cell shape and plasma membrane alterations after static magnetic fields exposure. Eur. J. Histoch. 47:299-308.
8. Chionna, A., Tenuzzo, B., Panzarini, E., et al. (2005). Time dependent modifications of Hep G2 cells during exposure to static magnetic fields. Bioelectromagnetics 26:275-286.
9. Dini, L., Abbro, L. (2005). Bioeffects of moderate-intensity static magnetic fields. Micron 36:195-217.
10. ++influx. FASEB J. 13:95-102.
11. Flores, E. R., Tsai, K. Y., Crowley, D., et al. (2002). p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 416:560-564.
12. Galli, C., Meucci, O., Scorziello, A., et al. (1995). Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. J. Neurosci. 15:1172-1179.
13. Guimaraes, C. A., Linden, R. (2004). Programmed cell death, apoptosis and alternative death styles. Eur. J. Biochem. 271:1638-1650.
14. Jajte, J. M. (2000). Programmed cell death as a biological function of electromagnetic fields at a frequency of (50/60 Hz). Med. Pr. 51:383-389.
15. Jajte, J., Grzegorczyk, J., Zmyślony, M., Rajkowska, E. (2002). Effect of 7 mT static magnetic field and iron ions on rat lymphocytes: apoptosis, necrosis and free radical processes. Bioelectrochemistry 57: 107-111.
16. Kim, J., Ha, C. S., Lee, H. J., Song, K. (2010). Repetitive exposure to a 60-Hz time varying magnetic field induces DNA double-strand breaks and apoptosis in human cells. Biochem. Biophys. Res. Commun. 400:739-744.
17. Lai, H., Singh, N. P. (2004). Magnetic field induced DNA strand breaks in brain cells of the rat. Environ. Health Perspect. 112:687-694.
18. Magnelli, L., Cinelli, M., Turchetti, A., Chiarugi, V. P. (1994). Bcl-2 overexpression abolishes early calcium waving preceding apoptosis in NIH-3T3 murine fibroblasts. Biochem. Biophys. Res. Commun. 204: 84-90.
19. Marinelli, F., La Sala, D., Cicciotti, G., et al. (2004). Exposure to 900 Mhz electromagnetic field induces an unbalance between pro-apoptotic and pro-survival signals in T-lymphoblastoid leukaemia CCRF-CEM cells. J. Cell. Physiol. 198:479-480.
20. 2+ concentration. Arch. Biochem. Biophys. 269: 365-370.
21. Moreira, M. E., Barcinski, M. A. (2004). Apoptotic cell and phagocyte interplay: Recognition and consequences in different cell systems. Ann. Acad. Brasil Sci. 76:93-115.
22. Nicholson, D. W., Thornberry, N. A. (1997). Caspases: Killer proteases. Trends Biochem. Sci. 22:299-306.
23. Powers, J. T., Hong, S., Mayhew, C. N., et al. (2004). E2F1 uses the ATM signaling pathway to induce p53 and chk2 phosphorylation and apoptosis. Mol. Cancer Res. 2:203-214.
24. Rosen, M. S., Rosen, A. D. (1990). Magnetic field influence on Paramecium motility. Life Sci. 46:1509-1515.
25. Rosen, A. D. (2003). Mechanism of action of moderate-intensity static magnetic fields. Biochem. Biophys. Acta 1282:149-155.
26. Stevens, R. G. (2004). Electromagnetic fields and free radicals. Environ. Health Perspect. 112:687-694.
27. Szatrowski, T. P., Nathan, C. F. (1991). Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 51:794-798.
28. Tenuzzo, B., Vergallo, C., Dini, L. (2009). Effect of 6 mT static magnetic field on the bcl-2, bax, p53 and hsp70 expression in freshly isolated and in vitro aged human lymphocytes. Tissue Cell 41:169-179.
29. Teodori, L., Gohde, W., Valente, M. G., et al. (2002a). Static magnetic fields affect calcium fluxes and inhibit stressinduced apoptosis in human glioblastoma cells. Cytometry 49:143-149.
30. Teodori, L., Grabarek, J., Smolewski, P., et al. (2002b). Exposure of cells to static magnetic fields accelerates loss of integrity of plasma membrane during apoptosis. Cytometry 49:113-118.
31. Urist, M., Tanaka, T., Poyurovsky, M. V., Prives, C. (2004). p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes Dev. 18:3041-3054.