Hypoxia-inducible factor-1α (HIF-1α) potentiates β-cell survival after islet transplantation of human and mouse islets

Cell Transplantation

Volumn 22, Issue 2, 2013, Pages 259-266

  Stokes, Rebecca A ^a   Cheng, Kim ^a   Deters, Natasha ^a   Lau, Sue Mei ^a   Hawthorne, Wayne J ^b   O'Connell, Philip J ^b   Stolp, Jessica ^c   Grey, Shane ^c   Loudovaris, Thomas ^d   Kay, Thomas W ^d   Thomas, Helen E ^d   Gonzalez, Frank J ^e   Gunton, Jenny E ^a,b,f,g  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b WESTMEAD HOSPITAL   (Australia)

^c GIMR   (Australia)

^d ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e NATIONAL CANCER INSTITUTE   (United States)

^f UNIVERSITY OF NEW SOUTH WALES   (Australia)

^g University of Sydney   (Australia)

Author keywords

cell function; Deferoxamine (DFO); Diabetes; Hypoxia; Hypoxia inducible factor 1 (HIF 1 ); Islet transplantation

Indexed keywords

CASPASE 3; DEFEROXAMINE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 1BETA; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B BETA; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CONTROL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GLUCOSE OXIDATION; GLUCOSE TOLERANCE; GLYCEMIC CONTROL; HUMAN; HUMAN CELL; HUMAN TISSUE; IRON CHELATION; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; ANIMAL; C57BL MOUSE; CELL HYPOXIA; DEFICIENCY; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PROCEDURES; SCID MOUSE;

ANIMALS; APOPTOSIS; CELL HYPOXIA; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, SCID; TRANSCRIPTION, GENETIC;

EID: 84874367752     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368912X647180     Document Type: Article

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