Methicillin resistance is not a predictor of severity in community-acquired Staphylococcus aureus necrotizing pneumonia-results of a prospective observational study

Clinical Microbiology and Infection

Volumn 19, Issue 3, 2013, Pages

  Sicot, N ^a   Khanafer, N ^b,c   Meyssonnier, V ^d   Dumitrescu, O ^a   Tristan, A ^a   Bes, M ^a   Lina, G ^a   Vandenesch, F ^a   Vanhems, P ^b,c   Etienne, J ^a   Gillet, Y ^a,e  

^a UNIVERSITÉ LYON 1   (France)

^b UNIVERSITÉ DE LYON   (France)

^c EDOUARD HERRIOT HOSPITAL   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e HOSPICES CIVILS DE LYON   (France)

Author keywords

Community acquired pneumonia; Methicillin resistance; Panton Valentine leucocidin; Staphylococcus aureus

Indexed keywords

ADULT; ARTICLE; CASE CONTROL STUDY; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DISEASE SEVERITY; HUMAN; MALE; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PENICILLIN RESISTANCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; STAPHYLOCOCCAL PNEUMONIA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS NECROTIZING PNEUMONIA;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 84874321147     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/1469-0691.12022     Document Type: Article

References (36)

1. Gillet Y, Issartel B, Vanhems P et al. Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet 2002; 359: 753-759.
2. Francis JS, Doherty MC, Lopatin U et al. Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. Clin Infect Dis 2005; 40: 100-107.
3. Hageman JC, Uyeki TM, Francis JS et al. Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season. Emerg Infect Dis 2006; 12: 894-899.
4. Klein E, Smith DL, Laxminarayan R. Community-associated methicillin-resistant Staphylococcus aureus in outpatients, United States, 1999-2006. Emerg Infect Dis 2009; 15: 1925-1930.
5. Naimi TS, LeDell KH, Como-Sabetti K et al. Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection. JAMA 2003; 290: 2976-2984.
6. Gillet Y, Etienne J, Lina G, Vandenesch F. Association of necrotizing pneumonia with Panton-Valentine leukocidin-producing Staphylococcus aureus, regardless of methicillin resistance. Clin Infect Dis 2008; 47: 985-986.
7. Kallen AJ, Brunkard J, Moore Z et al. Staphylococcus aureus community-acquired pneumonia during the 2006 to 2007 influenza season. Ann Emerg Med 2009; 53: 358-365.
8. Lina G, Piemont Y, Godail-Gamot F et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 1999; 29: 1128-1132.
9. Tristan A, Ferry T, Durand G et al. Virulence determinants in community and hospital methicillin-resistant Staphylococcus aureus. J Hosp Infect 2007; 65 (Suppl 2): 105-109.
10. Diep BA, Chan L, Tattevin P et al. Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci USA 2010; 107: 5587-5592.
11. Tristan A, Bes M, Meugnier H et al. Global distribution of Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus, 2006. Emerg Infect Dis 2007; 13: 594-600.
12. Vandenesch F, Couzon F, Boisset S et al. The Panton-Valentine leukocidin is a virulence factor in a murine model of necrotizing pneumonia. J Infect Dis 2010; 201: 967-969; author reply 9-70.
13. CDC. Severe methicillin-resistant Staphylococcus aureus community-acquired pneumonia associated with influenza - Louisiana and Georgia, December 2006-January 2007. MMWR Morb Mortal Wkly Rep 2007; 56: 325-329.
14. Cremieux AC, Dumitrescu O, Lina G et al. Panton-Valentine leukocidin enhances the severity of community-associated methicillin-resistant Staphylococcus aureus rabbit osteomyelitis. PLoS ONE 2009; 4: e7204.
15. Diep BA, Palazzolo-Ballance AM, Tattevin P et al. Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. PLoS ONE 2008; 3: e3198.
16. Labandeira-Rey M, Couzon F, Boisset S et al. Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science 2007; 315: 1130-1133.
17. Jarraud S, Mougel C, Thioulouse J et al. Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease. Infect Immun 2002; 70: 631-641.
18. CLS I. Performance standards for antimicrobial susceptibility testing. 14th informationnal supplement M100-S14. National Committee for Clinical Laboratory. 2004; Wayne, PA.
19. Murakami K, Minamide W, Wada K, Nakamura E, Teraoka H, Watanabe S. Identification of methicillin-resistant strains of staphylococci by polymerase chain reaction. J Clin Microbiol 1991; 29: 2240-2244.
20. Vardakas KZ, Matthaiou DK, Falagas ME. Comparison of community-acquired pneumonia due to methicillin-resistant and methicillin-susceptible Staphylococcus aureus producing the Panton-Valentine leukocidin. Int J Tuberc Lung Dis 2009; 13: 1476-1485.
21. CDC. Methicillin-resistant Staphylococcus aureus infections in correctional facilities - Georgia, California, and Texas, 2001-2003. MMWR Morb Mortal Wkly Rep 2003; 52: 992-996.
22. Miller LG, Quan C, Shay A et al. A prospective investigation of outcomes after hospital discharge for endemic, community-acquired methicillin-resistant and -susceptible Staphylococcus aureus skin infection. Clin Infect Dis 2007; 44: 483-492.
23. Diep BA, Stone GG, Basuino L et al. The arginine catabolic mobile element and staphylococcal chromosomal cassette mec linkage: convergence of virulence and resistance in the USA300 clone of methicillin-resistant Staphylococcus aureus. J Infect Dis 2008; 197: 1523-1530.
24. O'Hara FP, Guex N, Word JM et al. A geographic variant of the Staphylococcus aureus Panton-Valentine leukocidin toxin and the origin of community-associated methicillin-resistant S. aureus USA300. J Infect Dis 2008; 197: 187-194.
25. Li M, Cheung GY, Hu J et al. Comparative analysis of virulence and toxin expression of global community-associated methicillin-resistant Staphylococcus aureus strains. J Infect Dis 2010; 202: 1866-1876.
26. Badiou C, Dumitrescu O, George N et al. Rapid detection of Staphylococcus aureus Panton-Valentine leukocidin in clinical specimens by enzyme-linked immunosorbent assay and immunochromatographic tests. J Clin Microbiol 2010; 48: 1384-1390.
27. Dauwalder O, Lina G, Durand G et al. Epidemiology of invasive methicillin-resistant Staphylococcus aureus clones collected in France in 2006 and 2007. J Clin Microbiol 2008; 46: 3454-3458.
28. Kaito C, Saito Y, Nagano G et al. Transcription and translation products of the cytolysin gene psm-mec on the mobile genetic element SCCmec regulate Staphylococcus aureus virulence. PLoS Pathog 2011; 7: e1001267.
29. Gillet Y, Vanhems P, Lina G et al. Factors predicting mortality in necrotizing community-acquired pneumonia caused by Staphylococcus aureus containing Panton-Valentine leukocidin. Clin Infect Dis 2007; 45: 315-321.
30. Centers for Disease Control and Prevention (CDC). Severe coinfection with seasonal influenza A (H3N2) virus and Staphylococcus aureus- Maryland, February-March 2012. MMWR Morb Mortal Wkly Rep 2012; 61: 289-291.
31. Lobo LJ, Reed KD, Wunderink RG. Expanded clinical presentation of community-acquired MRSA pneumonia. Chest 2010; 138: 130-136.
32. Rouzic N, Janvier F, Libert N et al. Prompt and successful toxin-targeting treatment of three patients with necrotizing pneumonia due to Staphylococcus aureus strains carrying the Panton-Valentine leukocidin genes. J Clin Microbiol 2010; 48: 1952-1955.
33. Dumitrescu O, Badiou C, Bes M et al. Effect of antibiotics, alone and in combination, on Panton-Valentine leukocidin production by a Staphylococcus aureus reference strain. Clin Microbiol Infect 2008; 14: 384-388.
34. Dumitrescu O, Boisset S, Bes M et al. Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. Antimicrob Agents Chemother 2007; 51: 1515-1519.
35. Gauduchon V, Cozon G, Vandenesch F et al. Neutralization of Staphylococcus aureus Panton-Valentine leukocidin by intravenous immunoglobulin in vitro. J Infect Dis 2004; 189: 346-353.
36. Li HT, Zhang TT, Huang J, Zhou YQ, Zhu JX, Wu BQ. Factors associated with the outcome of life-threatening necrotizing pneumonia due to community-acquired Staphylococcus aureus in adult and adolescent patients. Respiration 2011; 81: 448-460.