Cytokine in cancer chemotherapy-Clinical trials of IL-3, IL-11 and Throm. Bopoietin against thrombocytopenia

Japanese Journal of Cancer and Chemotherapy

Volumn 25, Issue 1, 1998, Pages 171-176

  Kudoh, Shinzoh ^a   Yamada, Masashi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Chemotherapy; IL 11; IL 3; Thrombocytopenia; Thrombopoietin

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 11; INTERLEUKIN 3; PACLITAXEL; THROMBOPOIETIN;

BLOOD; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; DRUG ADMINISTRATION; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; PHASE 2 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; THROMBOCYTE COUNT; THROMBOCYTOPENIA; UNITED STATES;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARBOPLATIN; CARCINOMA, NON-SMALL-CELL LUNG; CLINICAL TRIALS; CLINICAL TRIALS, PHASE II; DRUG ADMINISTRATION SCHEDULE; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-11; INTERLEUKIN-3; LUNG NEOPLASMS; PACLITAXEL; PLATELET COUNT; RANDOMIZED CONTROLLED TRIALS; THROMBOCYTOPENIA; THROMBOPOIETIN; UNITED STATES;

EID: 84874307442     PISSN: 03850684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Slichter, S. J.: Principles of Platelet transfusion therapy. In: Hematology (eds. by Hoffman, R., Benz, E. J. Jr., Shattil, S. J. et al) : basic principles and practice. Churchill, Livingstone, New York, 1991, pp. 1610-1622.
2. Leary, A. G., Yang, Y.-C, Clark, S. C. et al: Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: Comparison with recombinant human granulocyte-macrophage colony-stimulating factor. Blood 70:1343-1348, 1987.
3. Sealand, S., Caux, C, Favre, C. et al: Effects of recombinant human interleukin-3 on CD 34-enriched normal hematopoietic progenitors and on myeloblastic leukemia cells. Blood 72: 1580-1588, 1988.
4. Sonoda, Y., Chang, Y.-C, Wong, G. G. et al: Analysis in serum-free culture of the targets of recombinant human hematopoietic growth factors : Interleukin 3 and granulocyte/macro-phage-colony-stimulating factor are specific for early developmental stages. Proc. Natl. Acad. Set. USA 85: 4360-4364, 1988.
5. Biesma, B., Willemse, P. H., Mulder, N. H. et al: Effects of interleukin-3 after chemotherapy for advanced ovarian cancer. Blood 80:1141-1148, 1992.
6. D'Hondt, V., Weynants, P., Humblet, Y. et al: Dose-dependent interleukin-3 stimulation of thrombopoiesis and neutropoiesis in patients with small-cell lung carcinoma before and following chemotherapy: a placebo-controlled randomized phase lb study. J. Clin. Oncol. 11: 2063-2071, 1993.
7. Kudoh, S., Sawa T., Ariyoshi, Y. et al: Phase II study of recombinant human interleukin 3 administration following carboplatin and etoposide chemotherapy in small-cell lung cancer patients. Cancer Chemother. Pharmacol. 38: S 89-S 95, 1996.
8. Lemoli, R. M., Rosti, G., Visani, G. et al: Concomitant and sequential administration of recombinant human granulocyte colony-stimulating factor and recombinant human interleukin-3 to accelerate hematopoietic recovery after autologous bone marrow transplantation for malignant lymphoma. J. Clin. Oncol. 14: 3018-3025, 1996.
9. Paul, S., Bennett, F., Calvetti, J. et al: Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Proc. Natl. Acad. Sci. USA 87 :7512, 1990.
10. Gordon, M.S., McCaskill - Stevens, W. J., Battiato, L. A. et al: A phase I trial of recombinant human interleukin-11 (neumega rhlL-11 growth factor) in women with breast cancer receiving chemotherapy. Blood 87: 3615-3624, 1996.
11. Tepler, I., Elias, L., Smith, J. et al: A randomized placebo-controlled trial of recombinant human interleukin-11 in cancer patients with severe thrombocytopenia due to chemotherapy. Blood 87 : 3607-3614, 1996.
12. Kato, T., Ogami, K., Shimada, Y. et al: Purification and characterization of thrombopoietin. J. Biochem. (Tokyo) 118:229-236, 1995.
13. Lok, S., Kaushansky, K., Holly, R.D. et al: Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 369: 565-568,1994.
14. de Sauvage, F. J., Hass, P. E., Spencer, S. D. et al: Stimulation of megakaryopoiesis and thrombopoiesis by the c-mpl ligand. Nature 369:533-538, 1994.
15. Wendling, F., Maraskovsky, E., Debill, N. et al: c-mpl ligand is a humoral regulator of megakaryopoiesis. Nature 369:571-574, 1994.
16. Bartley, T. D., Bogenberger, J., Hunt, P. et al: Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor mpl. Cell 77:1117-1124, 1994.
17. Kuter, D. J., Beeler, D. L. and Rosenberg, R. D.: The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production. Proc. Natl. Acad. Sci. USA 91:11104-11108, 1994.
18. Basser, R. L., Rasko, J. E. J., Ciarke, K. et al: Thrombopoietic effects of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) in patients with advanced cancer. Lancet 348: 1279-1281, 1996.
19. O'Malley, C. J., Rasko, J. E. J., Basser, R. L. et al: Administration of pegylated recombinant human megakaryocyte growth and development factor to humans stimulates the production of functional platelets that show no evidence of in vivo activation. Blood 88: 3288-3298, 1996.
20. Fanucchi, M., Glapsy, J., Crawford, J. et al: Effects of polyethyleneglycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer. N. Engl. J. Med. 336:404-409, 1997.