microRNA-18a, a member of the oncogenic miR-17-92 cluster, targets Dicer and suppresses cell proliferation in bladder cancer T24 cells

Molecular Medicine Reports

Volumn 5, Issue 1, 2012, Pages 167-172

  Tao, Jun ^a   Wu, Deyao ^a,b   Li, Pengchao ^a   Xu, Bin ^a   Lu, Qiang ^a   Zhang, Wei ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NANTONG MEDICAL COLLEGE   (China)

Author keywords

Bladder cancer; Dicer; microRNA 18a; miR 17 92 cluster; T24 cells

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DICER; MICRORNA; MICRORNA 18A; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; BINDING SITE; BLADDER CANCER; CANCER CELL; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN RNA BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

3' UNTRANSLATED REGIONS; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; DEAD-BOX RNA HELICASES; GENES, REPORTER; HUMANS; MICRORNAS; RIBONUCLEASE III; RNA INTERFERENCE; RNA, SMALL INTERFERING; URINARY BLADDER NEOPLASMS;

EID: 84855222726     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.591     Document Type: Article

References (27)

1. Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297, 2004.
2. Bernstein E, Kim SY, Carmell MA, et al.: Dicer is essential for mouse development. Nat Genet 35: 215-217, 2003. (Pubitemid 37363172)
3. Kanellopoulou C, Muljo SA, Kung AL, et al.: Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 19: 489-501, 2005. (Pubitemid 40256280)
4. Hayashita Y, Osada H, Tatematsu Y, et al.: A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 65: 9628-9632, 2005.
5. Takakura S, Mitsutake N, Nakashima M, et al.: Oncogenic role of miR-17-92 cluster in anaplastic thyroid cancer cells. Cancer Sci 99: 1147-1154, 2008. (Pubitemid 351676626)
6. Diosdado B, van de Wiel MA, Terhaar Sive Droste JS, et al.: MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br J Cancer 101: 707-714, 2009.
7. Chow TF, Mankaruos M, Scorilas A, et al.: The miR-17-92 cluster is over expressed in and has an oncogenic effect on renal cell carcinoma. J Urol 183: 743-751, 2010.
8. Rinaldi A, Poretti G, Kwee I, et al.: Concomitant MYC and microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma. Leuk Lymphoma 48: 410-412, 2007.
9. van Haaften G and Agami R: Tumorigenicity of the miR-17-92 cluster distilled. Genes Dev 24: 1-4, 2010.
10. He L, Thomson JM, Hemann MT, et al.: A microRNA polycistron as a potential human oncogene. Nature 435: 828-833, 2005.
11. O'Donnell KA, Wentzel EA, Zeller KI, Dang CV and Mendell JT: c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435: 839-843, 2005.
12. Olive V, Bennett MJ, Walker JC, et al.: miR-19 is a key oncogenic component of mir-17-92. Genes Dev 23: 2839-2849, 2009.
13. Bu Y, Lu C, Bian C, et al.: Knockdown of Dicer in MCF-7 human breast carcinoma cells results in G1 arrest and increased sensitivity to cisplatin. Oncol Rep 21: 13-17, 2009.
14. Maragkakis M, Reczko M, Simossis VA, et al.: DIANA-microT web server: elucidating microRNA functions through target prediction. Nucleic Acids Res 37: W273-W276, 2009.
15. Ohgawara T, Kubota S, Kawaki H, et al.: Regulation of chondrocytic phenotype by micro RNA 18a: involvement of Ccn2/Ctgf as a major target gene. FEBS Lett 583: 1006-1010, 2009.
16. Tsang WP and Kwok TT: The miR-18a*microRNA functions as a potential tumor suppressor by targeting on K-Ras. Carcinogenesis 30: 953-959, 2009.
17. Lee Y, Ahn C, Han J, et al.: The nuclear RNase III Drosha initiates microRNA processing. Nature 425: 415-419, 2003. (Pubitemid 37187272)
18. Jakymiw A, Patel RS, Deming N, et al.: Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells. Genes Chromosomes Cancer 49: 549-559, 2010.
19. Chiosea S, Jelezcova E, Chandran U, et al.: Overexpression of Dicer in precursor lesions of lung adenocarcinoma. Cancer Res 67: 2345-2350, 2007.
20. Martello G, Rosato A, Ferrari F, et al.: A MicroRNA targeting dicer for metastasis control. Cell 141: 1195-1207, 2010.
21. Pampalakis G, Diamandis EP, Katsaros D and Sotiropoulou G: Down-regulation of dicer expression in ovarian cancer tissues. Clin Biochem 43: 324-327, 2010.
22. Wu JF, Shen W, Liu NZ, et al.: Down-regulation of Dicer in hepatocellular carcinoma. Med Oncol 28: 804-809, 2010.
23. Pehlivan D, Gunduz E, Gunduz M, et al.: Loss of heterozygosity at chromosome 14q is associated with poor prognosis in head and neck squamous cell carcinomas. J Cancer Res Clin Oncol 134: 1267-1276, 2008.
24. Felsberg J, Yan PS, Huang TH, et al.: DNA methylation and allelic losses on chromosome arm 14q in oligodendroglial tumours. Neuropathol Appl Neurobiol 32: 517-524, 2006. (Pubitemid 44401513)
25. Al-Mulla F, AlFadhli S, Al-Hakim AH, Going JJ and Bitar MS: Metastatic recurrence of early-stage colorectal cancer is linked to loss of heterozygosity on chromosomes 4 and 14q. J Clin Pathol 59: 624-630, 2006. (Pubitemid 43886047)
26. Chang WY, Cairns P, Schoenberg MP, Polascik TJ and Sidransky D: Novel suppressor loci on chromosome 14q in primary bladder cancer. Cancer Res 55: 3246-3249, 1995.
27. Hastings RJ and Franks LM: Chromosome pattern, growth in agar and tumorigenicity in nude mice of four human bladder carcinoma cell lines. Int J Cancer 27: 15-21, 1981. (Pubitemid 11165587)