메뉴 건너뛰기




Volumn 3, Issue JAN, 2012, Pages

Novel immune modulators used in hematology: Impact on NK cells

Author keywords

bortezomib; Glivec ; HDACi; Imid ; Lenalidomide; NK cell; Thalidomide; TKi

Indexed keywords


EID: 84874296249     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2012.00388     Document Type: Review
Times cited : (45)

References (90)
  • 1
    • 84864143073 scopus 로고    scopus 로고
    • Dasatinib may overcome the negative prognostic impact of KIR2DS1 in newly diagnosed patients with chronic myeloid leukemia
    • Ali, S., Sergeant, R., O'Brien, S. G., Foroni, L., Hedgley, C., Ger-rard, G., et al. (2012). Dasatinib may overcome the negative prognostic impact of KIR2DS1 in newly diagnosed patients with chronic myeloid leukemia. Blood 120, 697-698.
    • (2012) Blood , vol.120 , pp. 697-698
    • Ali, S.1    Sergeant, R.2    O'Brien, S.G.3    Foroni, L.4    Hedgley, C.5    Ger-rard, G.6
  • 2
    • 84861406715 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon
    • Alvarez-Breckenridge, C. A., Yu, J., Price, R., Wei, M., Wang, Y., Nowicki, M. O., et al. (2012). The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon. J. Virol. 86, 4566-4577.
    • (2012) J. Virol. , vol.86 , pp. 4566-4577
    • Alvarez-Breckenridge, C.A.1    Yu, J.2    Price, R.3    Wei, M.4    Wang, Y.5    Nowicki, M.O.6
  • 3
    • 59249101291 scopus 로고    scopus 로고
    • Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition
    • Ames, E., Hallett, W H., and Murphy, W J. (2009). Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition. Clin. Exp. Immunol. 155, 504-513.
    • (2009) Clin. Exp. Immunol. , vol.155 , pp. 504-513
    • Ames, E.1    Hallett, W.H.2    Murphy, W.J.3
  • 4
    • 84874341407 scopus 로고    scopus 로고
    • Minimizing the immuno-suppressive effects of histone deacetylase inhibitors (HDACi): implications for therapy of cutaneous T-cell lymphoma (CTCL)
    • September 22-25, Chicago, IL
    • Anshelevich, A., Wysocka, M., Benoit, B. M., and Rook, A. H. (2010). "Minimizing the immuno-suppressive effects of histone deacetylase inhibitors (HDACi): implications for therapy of cutaneous T-cell lymphoma (CTCL)," in First World Congress of Cutaneous Lymphomas, September 22-25, Chicago, IL.
    • (2010) First World Congress of Cutaneous Lymphomas
    • Anshelevich, A.1    Wysocka, M.2    Benoit, B.M.3    Rook, A.H.4
  • 5
    • 22244485707 scopus 로고    scopus 로고
    • Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproate
    • Armeanu, S., Bitzer, M., Lauer, U. M., Venturelli, S., Pathil, A., Krusch, M., et al. (2005). Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproate. Cancer Res. 65, 6321-6329.
    • (2005) Cancer Res , vol.65 , pp. 6321-6329
    • Armeanu, S.1    Bitzer, M.2    Lauer, U.M.3    Venturelli, S.4    Pathil, A.5    Krusch, M.6
  • 6
    • 80052493233 scopus 로고    scopus 로고
    • Ima-tinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
    • Balachandran, V. P., Cavnar, M. J., Zeng, S., Bamboat, Z. M., Ocuin, L. M., Obaid, H., et al. (2011). Ima-tinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido. Nat.Med. 17, 1094-1100.
    • (2011) Nat. Med. , vol.17 , pp. 1094-1100
    • Balachandran, V.P.1    Cavnar, M.J.2    Zeng, S.3    Bamboat, Z.M.4    Ocuin, L.M.5    Obaid, H.6
  • 7
    • 0037085760 scopus 로고    scopus 로고
    • Leukemic target susceptibility to natural killer cytotoxicity: relationship with BCR-ABL expression
    • Baron, F., Turhan, A. G., Giron-Michel, J., Azzarone, B., Bentires-Alj, M., Bours, V., et al. (2002). Leukemic target susceptibility to natural killer cytotoxicity: relationship with BCR-ABL expression. Blood 99, 2107-2113.
    • (2002) Blood , vol.99 , pp. 2107-2113
    • Baron, F.1    Turhan, A.G.2    Giron-Michel, J.3    Azzarone, B.4    Bentires-Alj, M.5    Bours, V.6
  • 8
    • 1942534043 scopus 로고    scopus 로고
    • The evolution of thalidomide and its IMiD derivatives as anticancer agents
    • Bartlett, J. B., Dredge, K., and Dal-gleish, A. G. (2004a). The evolution of thalidomide and its IMiD derivatives as anticancer agents. Nat. Rev. Cancer 4, 314-322.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 314-322
    • Bartlett, J.B.1    Dredge, K.2    Dal-gleish, A.G.3
  • 9
    • 11144355748 scopus 로고    scopus 로고
    • Phase I study to determine the safety, tolera-bility and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers
    • Bartlett, J. B., Michael, A., Clarke, I. A., Dredge, K., Nicholson, S., Kris-teleit, H., et al. (2004b). Phase I study to determine the safety, tolera-bility and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers. Br. J. Cancer 90, 955-961.
    • (2004) Br. J. Cancer , vol.90 , pp. 955-961
    • Bartlett, J.B.1    Michael, A.2    Clarke, I.A.3    Dredge, K.4    Nicholson, S.5    Kris-teleit, H.6
  • 11
    • 43249096013 scopus 로고    scopus 로고
    • Dasatinib suppresses in vitro natural killer cell cytotoxicity
    • Blake, S. J., Bruce Lyons, A., Fraser, C. K., Hayball, J. D., and Hughes, T. P. (2008). Dasatinib suppresses in vitro natural killer cell cytotoxicity. Blood 111, 4415-4416.
    • (2008) Blood , vol.111 , pp. 4415-4416
    • Blake, S.J.1    Bruce Lyons, A.2    Fraser, C.K.3    Hayball, J.D.4    Hughes, T.P.5
  • 12
    • 33645767415 scopus 로고    scopus 로고
    • BCR/ABL oncogene directly controls MHC class I chain-related molecule A expression in chronic myelogenous leukemia
    • Boissel, N., Rea, D., Tieng, V., Dulphy, N., Brun, M., Cayuela, J. M., et al. (2006). BCR/ABL oncogene directly controls MHC class I chain-related molecule A expression in chronic myelogenous leukemia. J. Immunol. 176, 5108-5116.
    • (2006) J. Immunol. , vol.176 , pp. 5108-5116
    • Boissel, N.1    Rea, D.2    Tieng, V.3    Dulphy, N.4    Brun, M.5    Cayuela, J.M.6
  • 13
    • 4043134677 scopus 로고    scopus 로고
    • Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects
    • Borg, C., Terme, M., Taïeb, J., Ménard, C., Flament, C., Robert, C., et al. (2004). Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects. J. Clin. Invest. 114, 379-388.
    • (2004) J. Clin. Invest. , vol.114 , pp. 379-388
    • Borg, C.1    Terme, M.2    Taïeb, J.3    Ménard, C.4    Flament, C.5    Robert, C.6
  • 15
    • 30744462293 scopus 로고    scopus 로고
    • The decreased susceptibility of Bcr/Abl targets to NK cell-mediated lysis in response to imatinib mesylate involves modulation of NKG2D ligands, GM1 expression, and synapse formation
    • Cebo, C., Da Rocha, S., Wittnebel, S., Turhan, A. G., Abdelali, J., Caillat-Zucman, S., et al. (2006). The decreased susceptibility of Bcr/Abl targets to NK cell-mediated lysis in response to imatinib mesylate involves modulation of NKG2D ligands, GM1 expression, and synapse formation. J. Immunol. 176, 864-872.
    • (2006) J. Immunol. , vol.176 , pp. 864-872
    • Cebo, C.1    Da Rocha, S.2    Wittnebel, S.3    Turhan, A.G.4    Abdelali, J.5    Caillat-Zucman, S.6
  • 16
    • 27144509642 scopus 로고    scopus 로고
    • Epige-netic control of highly homologous killer Ig-like receptor gene alleles
    • Chan, H. W., Miller, J. S., Moore, M. B., and Lutz, C. T. (2005). Epige-netic control of highly homologous killer Ig-like receptor gene alleles. J. Immunol. 175, 5966-5974.
    • (2005) J. Immunol. , vol.175 , pp. 5966-5974
    • Chan, H.W.1    Miller, J.S.2    Moore, M.B.3    Lutz, C.T.4
  • 17
    • 84857996055 scopus 로고    scopus 로고
    • NK cells are dysfunctional in human chronic myelogenous leukemia before and on imatinib treatment and in BCR-ABL-positive mice
    • Chen, C. I., Koschmieder, S., Kerstiens, L., Schemionek, M., Altvater, B., Pscherer, S., et al. (2012). NK cells are dysfunctional in human chronic myelogenous leukemia before and on imatinib treatment and in BCR-ABL-positive mice. Leukemia 26, 465-474.
    • (2012) Leukemia , vol.26 , pp. 465-474
    • Chen, C.I.1    Koschmieder, S.2    Kerstiens, L.3    Schemionek, M.4    Altvater, B.5    Pscherer, S.6
  • 18
    • 53749086585 scopus 로고    scopus 로고
    • Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling
    • Chen, J., Schmitt, A., Chen, B., Rojew-ski, M., Rübeler, V., Fei, F., et al. (2008). Nilotinib hampers the proliferation and function of CD8+ T lymphocytes through inhibition of T cell receptor signalling. J. Cell. Mol. Med. 12, 2107-2118.
    • (2008) J. Cell. Mol. Med. , vol.12 , pp. 2107-2118
    • Chen, J.1    Schmitt, A.2    Chen, B.3    Rojew-ski, M.4    Rübeler, V.5    Fei, F.6
  • 19
    • 0037068379 scopus 로고    scopus 로고
    • 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy
    • Christman, J. K. (2002). 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy. Oncogene 21, 5483-5495.
    • (2002) Oncogene , vol.21 , pp. 5483-5495
    • Christman, J.K.1
  • 20
    • 77955092382 scopus 로고    scopus 로고
    • Lenalido-mide down regulates the production of interferon-gamma and the expression of inhibitory cytotoxic receptors of human natural killer cells
    • Dauguet, N., Fournie, J., Poupot, R., and Poupot, M. (2010). Lenalido-mide down regulates the production of interferon-gamma and the expression of inhibitory cytotoxic receptors of human natural killer cells. Cell. Immunol. 264, 163-170.
    • (2010) Cell. Immunol. , vol.264 , pp. 163-170
    • Dauguet, N.1    Fournie, J.2    Poupot, R.3    Poupot, M.4
  • 21
    • 0035412366 scopus 로고    scopus 로고
    • Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
    • Davies, F. E., Raje, N., Hideshima, T., Lentzsch, S., Young, G., Tai, Y. T., et al. (2001). Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma. Blood 98, 210-216.
    • (2001) Blood , vol.98 , pp. 210-216
    • Davies, F.E.1    Raje, N.2    Hideshima, T.3    Lentzsch, S.4    Young, G.5    Tai, Y.T.6
  • 22
    • 38949193232 scopus 로고    scopus 로고
    • NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities
    • Diermayr, S., Himmelreich, H., Durovic, B., Mathys-Schneeberger, A., Siegler, U., Langenkamp, U., et al. (2008). NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities. Blood 111, 1428-1436.
    • (2008) Blood , vol.111 , pp. 1428-1436
    • Diermayr, S.1    Himmelreich, H.2    Durovic, B.3    Mathys-Schneeberger, A.4    Siegler, U.5    Langenkamp, U.6
  • 23
    • 77955415749 scopus 로고    scopus 로고
    • The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells
    • Feng, X., Yan, J., Wang, Y., Zierath, J. R., Nordenskjöld, M., Henter, J. I., et al. (2010). The proteasome inhibitor bortezomib disrupts tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression and natural killer (NK) cell killing of TRAIL receptor-positive multiple myeloma cells. Mol. Immunol. 47, 2388-2396.
    • (2010) Mol. Immunol. , vol.47 , pp. 2388-2396
    • Feng, X.1    Yan, J.2    Wang, Y.3    Zierath, J.R.4    Nordenskjöld, M.5    Henter, J.I.6
  • 24
    • 58149181387 scopus 로고    scopus 로고
    • Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo
    • Fraser, C. K., Blake, S. J., Diener, K. R., Lyons, A. B., Brown, M. P., Hughes, T. P., et al. (2009). Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo. Exp. Hematol. 37, 256-265.
    • (2009) Exp. Hematol. , vol.37 , pp. 256-265
    • Fraser, C.K.1    Blake, S.J.2    Diener, K.R.3    Lyons, A.B.4    Brown, M.P.5    Hughes, T.P.6
  • 25
    • 67349255288 scopus 로고    scopus 로고
    • Demethylating treatment suppresses natural killer cell cytolytic activity
    • Gao, X. N., Lin, J., Wang, L. L., and Yu, L. (2009). Demethylating treatment suppresses natural killer cell cytolytic activity. Mol. Immunol. 46, 2064-2070.
    • (2009) Mol. Immunol. , vol.46 , pp. 2064-2070
    • Gao, X.N.1    Lin, J.2    Wang, L.L.3    Yu, L.4
  • 26
    • 55749110754 scopus 로고    scopus 로고
    • Demethylating agents in myeloid malignancies
    • Garcia-Manero, G. (2008). Demethylating agents in myeloid malignancies. Curr. Opin. Oncol. 20, 705-710.
    • (2008) Curr. Opin. Oncol. , vol.20 , pp. 705-710
    • Garcia-Manero, G.1
  • 27
    • 24144443517 scopus 로고    scopus 로고
    • The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
    • Gasser, S., Orsulic, S., Brown, E. J., and Raulet, D. H. (2005). The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 436, 1186-1190.
    • (2005) Nature , vol.436 , pp. 1186-1190
    • Gasser, S.1    Orsulic, S.2    Brown, E.J.3    Raulet, D.H.4
  • 28
    • 34547897023 scopus 로고    scopus 로고
    • Histone deacetylases and cancer
    • Glozak, M. A., and Seto, E. (2007). Histone deacetylases and cancer. Oncogene 26, 5420-5432.
    • (2007) Oncogene , vol.26 , pp. 5420-5432
    • Glozak, M.A.1    Seto, E.2
  • 29
    • 78049386125 scopus 로고    scopus 로고
    • Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma
    • Gorgun, G., Calabrese, E., Soydan, E., Hideshima, T., Perrone, G., Bandi, M., et al. (2010). Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma. Blood 116, 3227-3237.
    • (2010) Blood , vol.116 , pp. 3227-3237
    • Gorgun, G.1    Calabrese, E.2    Soydan, E.3    Hideshima, T.4    Perrone, G.5    Bandi, M.6
  • 30
    • 40449100492 scopus 로고    scopus 로고
    • Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition
    • Hallett, W H., Ames, E., Motarjemi, M., Barao, I., Shanker, A., Tamang, D. L., et al. (2008). Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition. J. Immunol. 180, 163-170.
    • (2008) J. Immunol. , vol.180 , pp. 163-170
    • Hallett, W.H.1    Ames, E.2    Motarjemi, M.3    Barao, I.4    Shanker, A.5    Tamang, D.L.6
  • 31
    • 84864152607 scopus 로고    scopus 로고
    • Enhancement of natural killer cell effector functions against selected lymphoma and leukemia cell lines by dasatinib
    • Hassold, N., Seystahl, K., Kempf, K., Urlaub, D., Zekl, M., Einsele, H., et al. (2012). Enhancement of natural killer cell effector functions against selected lymphoma and leukemia cell lines by dasatinib. Int. J. Cancer 131, E916-E927.
    • (2012) Int. J. Cancer , vol.131
    • Hassold, N.1    Seystahl, K.2    Kempf, K.3    Urlaub, D.4    Zekl, M.5    Einsele, H.6
  • 32
    • 19944430437 scopus 로고    scopus 로고
    • Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application
    • Hayashi, T., Hideshima, T., Akiyama, M., Podar, K., Yasui, H., Raje, N., et al. (2005). Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application. Br. J. Haematol. 128, 192-203.
    • (2005) Br. J. Haematol. , vol.128 , pp. 192-203
    • Hayashi, T.1    Hideshima, T.2    Akiyama, M.3    Podar, K.4    Yasui, H.5    Raje, N.6
  • 33
    • 23844435619 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model
    • Hernandez-Ilizaliturri, F. J., Reddy, N., Holkova, B., Ottman, E., and Czucz-man, M. S. (2005). Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model. Clin. Cancer Res. 11, 5984-5992.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 5984-5992
    • Hernandez-Ilizaliturri, F.J.1    Reddy, N.2    Holkova, B.3    Ottman, E.4    Czucz-man, M.S.5
  • 34
    • 79955691460 scopus 로고    scopus 로고
    • Role of sorafenib and sunitinib in the induction of expressions of NKG2D ligands in nasopharyngeal carcinoma with high expression of ABCG2
    • Huang, Y., Wang, Y., Li, Y., Guo, K., and He, Y. (2011). Role of sorafenib and sunitinib in the induction of expressions of NKG2D ligands in nasopharyngeal carcinoma with high expression of ABCG2. J. Cancer Res. Clin. Oncol. 137, 829-837.
    • (2011) J. Cancer Res. Clin. Oncol. , vol.137 , pp. 829-837
    • Huang, Y.1    Wang, Y.2    Li, Y.3    Guo, K.4    He, Y.5
  • 36
    • 84870897858 scopus 로고    scopus 로고
    • Sensitizing primary acute lymphoblastic leukemia to natural killer cell recognition by induction of NKG2D ligands
    • doi: 10.3109/10428194.2012.708026 [Epub ahead of print]
    • Jardine, L., Hambleton, S., Bigley, V., Pagan, S., Wang, X. N., and Collin, M. (2012). Sensitizing primary acute lymphoblastic leukemia to natural killer cell recognition by induction of NKG2D ligands. Leuk. Lymphoma. doi: 10.3109/10428194.2012.708026 [Epub ahead of print].
    • (2012) Leuk. Lymphoma.
    • Jardine, L.1    Hambleton, S.2    Bigley, V.3    Pagan, S.4    Wang, X.N.5    Collin, M.6
  • 37
    • 34548779134 scopus 로고    scopus 로고
    • Regulation of the expression of MHC class I-related chain A, B (MICA MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells
    • Kato, N., Tanaka, J., Sugita, J., Toubai, T., Miura, Y., Ibata, M., et al. (2007). Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells. Leukemia 21, 2103-2108.
    • (2007) Leukemia , vol.21 , pp. 2103-2108
    • Kato, N.1    Tanaka, J.2    Sugita, J.3    Toubai, T.4    Miura, Y.5    Ibata, M.6
  • 38
    • 84862777176 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients
    • Kelly-Sell, M. J., Kim, Y H., Straus, S., Benoit, B., Harrison, C., Sutherland, K., et al. (2012). The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients. Am. J. Hematol. 87, 354-360.
    • (2012) Am. J. Hematol. , vol.87 , pp. 354-360
    • Kelly-Sell, M.J.1    Kim, Y.H.2    Straus, S.3    Benoit, B.4    Harrison, C.5    Sutherland, K.6
  • 39
    • 84855471990 scopus 로고    scopus 로고
    • HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications
    • Khan, O., and La Thangue, N. B. (2012). HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications. Immunol. Cell Biol. 90, 85-94.
    • (2012) Immunol. Cell Biol. , vol.90 , pp. 85-94
    • Khan, O.1    La Thangue, N.B.2
  • 40
    • 58149267985 scopus 로고    scopus 로고
    • Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia
    • Kim, D. H., Kamel-Reid, S., Chang, H., Sutherland, R., Jung, C. W., Kim, H. J., et al. (2009). Natural killer or natural killer/T cell lineage large granular lymphocytosis associated with dasatinib therapy for Philadelphia chromosome positive leukemia. Haema-tologica94, 135-139.
    • (2009) Haema-tologica94 , pp. 135-139
    • Kim, D.H.1    Kamel-Reid, S.2    Chang, H.3    Sutherland, R.4    Jung, C.W.5    Kim, H.J.6
  • 41
    • 77950613332 scopus 로고    scopus 로고
    • Sorafenib inhibits the shedding of major histocompatibil-ity complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9
    • Kohga, K., Takehara, T., Tatsumi, T., Ishida, H., Miyagi, T., Hosui, A., et al. (2010). Sorafenib inhibits the shedding of major histocompatibil-ity complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9. Hepatology 51, 1264-1273.
    • (2010) Hepatology , vol.51 , pp. 1264-1273
    • Kohga, K.1    Takehara, T.2    Tatsumi, T.3    Ishida, H.4    Miyagi, T.5    Hosui, A.6
  • 42
    • 84867399697 scopus 로고    scopus 로고
    • Killer-cell immunoglobulin-like receptor gene profile predicts good molecular response to dasatinib therapy in chronic myeloid leukemia
    • e1
    • Kreutzman, A., Jaatinen, T., Greco, D., Vakkila, E., Richter, J., Ekblom, M., et al. (2012). Killer-cell immunoglobulin-like receptor gene profile predicts good molecular response to dasatinib therapy in chronic myeloid leukemia. Exp. Hematol. 40, 906-913.e1.
    • (2012) Exp. Hematol. , vol.40 , pp. 906-913
    • Kreutzman, A.1    Jaatinen, T.2    Greco, D.3    Vakkila, E.4    Richter, J.5    Ekblom, M.6
  • 43
    • 77956280601 scopus 로고    scopus 로고
    • Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy
    • Kreutzman, A., Juvonen, V., Kairisto, V., Ekblom, M., Stenke, L., Seggewiss, R., et al. (2010). Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy. Blood 116, 772-782.
    • (2010) Blood , vol.116 , pp. 772-782
    • Kreutzman, A.1    Juvonen, V.2    Kairisto, V.3    Ekblom, M.4    Stenke, L.5    Seggewiss, R.6
  • 44
    • 82255169327 scopus 로고    scopus 로고
    • Effects of BCR-ABL inhibitors on anti-tumor immunity
    • Krusch, M., and Salih, H. R. (2011). Effects of BCR-ABL inhibitors on anti-tumor immunity. Curr. Med. Chem. 18,5174-5184.
    • Curr. Med. Chem. , vol.18 , pp. 5174-5184
    • Krusch, M.1    Salih, H.R.2
  • 45
    • 76249129410 scopus 로고    scopus 로고
    • The kinase inhibitors sunitinib and sorafenib differentially affect NK cell antitumor reactivity in vitro
    • Krusch, M., Salih, J., Schlicke, M., Baessler, T., Kampa, K. M., Mayer, E, et al. (2009). The kinase inhibitors sunitinib and sorafenib differentially affect NK cell antitumor reactivity in vitro.J. Immunol. 183, 8286-8294.
    • (2011) J. Immunol , vol.183 , pp. 8286-8294
    • Krusch, M.1    Salih, J.2    Schlicke, M.3    Baessler, T.4    Kampa, K.M.5    Mayer, E.6
  • 46
    • 76749162262 scopus 로고    scopus 로고
    • Lenalidomide as salvage therapy after allo-SCT for multiple myeloma is effective and leads to an increase of activated NK (NKp44+) and T (HLA-DR+) cells
    • Lioznov, M., El-Cheikh, J. Jr., Hoffmann, F., Hildebrandt, Y., Ayuk, E, Wolschke, C., et al. (2010). Lenalidomide as salvage therapy after allo-SCT for multiple myeloma is effective and leads to an increase of activated NK (NKp44+) and T (HLA-DR+) cells. Bone Marrow Transplant. 45, 349-353.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 349-353
    • Lioznov, M.1    El-Cheikh Jr., J.2    Hoffmann, F.3    Hildebrandt, Y.4    Ayuk, E.5    Wolschke, C.6
  • 47
    • 33746917919 scopus 로고    scopus 로고
    • Borte-zomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity
    • Lundqvist, A., Abrams, S. I., Schrump, D. S., Alvarez, G., Suffredini, D., Berg, M., et al. (2006). Borte-zomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Res. 66, 7317-7325.
    • (2006) Cancer Res , vol.66 , pp. 7317-7325
    • Lundqvist, A.1    Abrams, S.I.2    Schrump, D.S.3    Alvarez, G.4    Suffredini, D.5    Berg, M.6
  • 48
    • 84861669615 scopus 로고    scopus 로고
    • Borte-zomib treatment to potentiate the anti-tumor immunity of ex-vivo expanded adoptively infused autolo-gous natural killer cells
    • Lundqvist, A., Berg, M., Smith, A., and Childs, R. W. (2011). Borte-zomib treatment to potentiate the anti-tumor immunity of ex-vivo expanded adoptively infused autolo-gous natural killer cells. J. Cancer 2, 383-385.
    • (2011) J. Cancer , vol.2 , pp. 383-385
    • Lundqvist, A.1    Berg, M.2    Smith, A.3    Childs, R.W.4
  • 49
    • 77949331656 scopus 로고    scopus 로고
    • Cutting edge: bortezomib-treated tumors sensitized to NK cell apoptosis paradoxically acquire resistance to antigen-specific T cells
    • Lundqvist, A., Su, S.,Rao, S., and Childs, R. (2010). Cutting edge: bortezomib-treated tumors sensitized to NK cell apoptosis paradoxically acquire resistance to antigen-specific T cells. J. Immunol. 184, 1139-1142.
    • (2010) J. Immunol. , vol.184 , pp. 1139-1142
    • Lundqvist, A.1    Su, S.2    Rao, S.3    Childs, R.4
  • 50
    • 67650355477 scopus 로고    scopus 로고
    • Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells
    • Lundqvist, A., Yokoyama, H., Smith, A., Berg, M., and Childs, R. (2009). Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells. Blood 113, 6120-6127.
    • (2009) Blood , vol.113 , pp. 6120-6127
    • Lundqvist, A.1    Yokoyama, H.2    Smith, A.3    Berg, M.4    Childs, R.5
  • 51
    • 79953781185 scopus 로고    scopus 로고
    • Immunocompetent cell functions in Ph+ acute lym-phoblastic leukemia patients on prolonged imatinib maintenance treatment
    • Maggio, R., Peragine, N., De Propris, M. S., Vitale, A., Elia, L., Calabrese, E., et al. (2011). Immunocompetent cell functions in Ph+ acute lym-phoblastic leukemia patients on prolonged imatinib maintenance treatment. Cancer Immunol. Immunother. 60, 599-607.
    • (2011) Cancer Immunol. Immunother. , vol.60 , pp. 599-607
    • Maggio, R.1    Peragine, N.2    De Propris, M.S.3    Vitale, A.4    Elia, L.5    Calabrese, E.6
  • 52
    • 84856704243 scopus 로고    scopus 로고
    • KIR2DS1 genotype predicts for complete cyto-genetic response and survival in newly diagnosed chronic myeloid leukemia patients treated with imatinib
    • Marin, D., Gabriel, I. H., Ahmad, S., Foroni, L., de Lavallade, H., Clark, R., et al. (2012). KIR2DS1 genotype predicts for complete cyto-genetic response and survival in newly diagnosed chronic myeloid leukemia patients treated with imatinib. Leukemia 26, 296-302.
    • (2012) Leukemia , vol.26 , pp. 296-302
    • Marin, D.1    Gabriel, I.H.2    Ahmad, S.3    Foroni, L.4    de Lavallade, H.5    Clark, R.6
  • 53
    • 67650090545 scopus 로고    scopus 로고
    • His-tone deacetylase inhibitors: potential in cancer therapy
    • Marks, P. A., and Xu, W. S. (2009). His-tone deacetylase inhibitors: potential in cancer therapy. J. Cell. Biochem. 107, 600-608.
    • (2009) J. Cell. Biochem. , vol.107 , pp. 600-608
    • Marks, P.A.1    Xu, W.S.2
  • 54
    • 65949085379 scopus 로고    scopus 로고
    • Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients
    • Menard, C., Blay, J. Y., Borg, C., Michiels, S., Ghiringhelli, F., Robert, C., et al. (2009). Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients. Cancer Res. 69, 3563-3569.
    • (2009) Cancer Res , vol.69 , pp. 3563-3569
    • Menard, C.1    Blay, J.Y.2    Borg, C.3    Michiels, S.4    Ghiringhelli, F.5    Robert, C.6
  • 55
    • 68749108104 scopus 로고    scopus 로고
    • Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
    • Mustjoki, S., Ekblom, M., Dybedal, I., Epling-Burnette, P. K., Guilhot, E, et al. (2009). Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Leukemia 23, 1398-1405.
    • (2009) Leukemia , vol.23 , pp. 1398-1405
    • Mustjoki, S.1    Ekblom, M.2    Dybedal, I.3    Epling-Burnette, P.K.4    Guilhot, E.5
  • 56
    • 84859787650 scopus 로고    scopus 로고
    • Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benza-mide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity
    • Ning, Z. Q., Li, Z. B., Newman, M. J., Shan, S., Wang, X. H., Pan, D. S., et al. (2012). Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benza-mide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity. Cancer Chemother. Pharmacol. 69, 901-909.
    • (2012) Cancer Chemother. Pharmacol. , vol.69 , pp. 901-909
    • Ning, Z.Q.1    Li, Z.B.2    Newman, M.J.3    Shan, S.4    Wang, X.H.5    Pan, D.S.6
  • 57
    • 33947429267 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors suppress natural killer cell cytolytic activity
    • Ogbomo, H., Michaelis, M., Kreuter, J., Doerr, H. W., and Cinatl, J. Jr. (2007). Histone deacetylase inhibitors suppress natural killer cell cytolytic activity. FEBSLett. 581, 1317-1322.
    • (2007) FEBSLett , vol.581 , pp. 1317-1322
    • Ogbomo, H.1    Michaelis, M.2    Kreuter, J.3    Doerr, H.W.4    Cinatl Jr., J.5
  • 58
    • 84859218819 scopus 로고    scopus 로고
    • Increased natural killer cells and decreased CD3+ CD8+ CD62L+ T cells in CML patients who sustained complete molecular remission after discontinuation of imatinib
    • Ohyashiki, K., Katagiri, S., Tauchi, T., Ohyashiki, J. H., Maeda, Y., Matsumura, I., et al. (2012). Increased natural killer cells and decreased CD3+ CD8+ CD62L+ T cells in CML patients who sustained complete molecular remission after discontinuation of imatinib. Br. J. Haematol. 157, 254-256.
    • (2012) Br. J. Haematol. , vol.157 , pp. 254-256
    • Ohyashiki, K.1    Katagiri, S.2    Tauchi, T.3    Ohyashiki, J.H.4    Maeda, Y.5    Matsumura, I.6
  • 59
    • 41549133200 scopus 로고    scopus 로고
    • Proteasome inhibitors in cancer therapy: lessons from the first decade
    • Orlowski, R. Z., and Kuhn, D. J. (2008). Proteasome inhibitors in cancer therapy: lessons from the first decade. Clin. Cancer Res. 14, 1649-1657.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 1649-1657
    • Orlowski, R.Z.1    Kuhn, D.J.2
  • 60
    • 27144458424 scopus 로고    scopus 로고
    • ®) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT
    • Payvandi, F., Wu, L., Naziruddin, S. D., Haley, M., Parton, A., Schafer, P. H., et al. (2005). Immunomodulatory drugs (IMiDs®) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT. J. Interferon Cytokine Res. 25, 604-616.
    • (2005) J. Interferon Cytokine Res. , vol.25 , pp. 604-616
    • Payvandi, F.1    Wu, L.2    Naziruddin, S.D.3    Haley, M.4    Parton, A.5    Schafer, P.H.6
  • 61
  • 62
    • 79951810777 scopus 로고    scopus 로고
    • The effect of sunitinib on immune subsets in metastatic clear cell renal cancer
    • Powles, T., Chowdhury, S., Bower, M., Saunders, N., Lim, L., Shamash, J., et al. (2011). The effect of sunitinib on immune subsets in metastatic clear cell renal cancer. Urol. Int. 86, 53-59.
    • (2011) Urol. Int. , vol.86 , pp. 53-59
    • Powles, T.1    Chowdhury, S.2    Bower, M.3    Saunders, N.4    Lim, L.5    Shamash, J.6
  • 63
    • 36849024949 scopus 로고    scopus 로고
    • Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo
    • Reddy, N., Hernandez-Ilizaliturri, E J., Deeb, G., Roth, M., Vaughn, M., Knight, J., et al. (2008). Immunomodulatory drugs stimulate natural killer-cell function, alter cytokine production by dendritic cells, and inhibit angiogenesis enhancing the anti-tumour activity of rituximab in vivo. Br. J. Haematol. 140, 36-45.
    • (2008) Br. J. Haematol. , vol.140 , pp. 36-45
    • Reddy, N.1    Hernandez-Ilizaliturri, E.J.2    Deeb, G.3    Roth, M.4    Vaughn, M.5    Knight, J.6
  • 64
    • 34547667110 scopus 로고    scopus 로고
    • Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis
    • Rohner, A., Langenkamp, U., Siegler, U., Kalberer, C. P., and Wodnar-Filipowicz, A. (2007). Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis. Leuk. Res. 31, 1393-1402.
    • (2007) Leuk. Res. , vol.31 , pp. 1393-1402
    • Rohner, A.1    Langenkamp, U.2    Siegler, U.3    Kalberer, C.P.4    Wodnar-Filipowicz, A.5
  • 65
    • 84856490854 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression
    • Rossi, L. E., Avila, D. E., Spallan-zani, R. G., Ziblat, A., Fuertes, M, B., Lapyckyj, L., et al. (2012). Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression. J. Leukoc. Biol. 91, 321-331.
    • (2012) J. Leukoc. Biol. , vol.91 , pp. 321-331
    • Rossi, L.E.1    Avila, D.E.2    Spallan-zani, R.G.3    Ziblat, A.4    Fuertes, M.5    Lapyckyj, B.L.6
  • 66
    • 77956634317 scopus 로고    scopus 로고
    • The BCR/ABL-inhibitors imatinib, nilotinib and dasatinib differentially affect NK cell reactivity
    • Salih, J., Hilpert, J., Placke, T., Grünebach, F., Steinle, A., Salih, H. R., et al. (2010). The BCR/ABL-inhibitors imatinib, nilotinib and dasatinib differentially affect NK cell reactivity. Int. J. Cancer 127, 2119-2128.
    • (2010) Int. J. Cancer , vol.127 , pp. 2119-2128
    • Salih, J.1    Hilpert, J.2    Placke, T.3    Grünebach, F.4    Steinle, A.5    Salih, H.R.6
  • 67
    • 0037108489 scopus 로고    scopus 로고
    • Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells
    • Santourlidis, S., Trompeter, H. I., Wein-hold, S., Eisermann, B., Meyer, K. L., Wernet, P., et al. (2002). Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells. J. Immunol. 169, 4253-4261.
    • (2002) J. Immunol. , vol.169 , pp. 4253-4261
    • Santourlidis, S.1    Trompeter, H.I.2    Wein-hold, S.3    Eisermann, B.4    Meyer, K.L.5    Wernet, P.6
  • 68
    • 38949210227 scopus 로고    scopus 로고
    • Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation
    • Schade, A. E., Schieven, G. L., Townsend, R., Jankowska, A. M., Susulic, V., Zhang, R., et al. (2008). Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation. Blood 111, 1366-1377.
    • (2008) Blood , vol.111 , pp. 1366-1377
    • Schade, A.E.1    Schieven, G.L.2    Townsend, R.3    Jankowska, A.M.4    Susulic, V.5    Zhang, R.6
  • 69
    • 79955413027 scopus 로고    scopus 로고
    • Azacyti-dine impairs NK cell reactivity while decitabine augments NK cell responsiveness toward stimulation
    • Schmiedel, B. J., Arélin, V., Gruenebach, E, Krusch, M., Schmidt, S. M., Salih, H. R., et al. (2011). Azacyti-dine impairs NK cell reactivity while decitabine augments NK cell responsiveness toward stimulation. Int. J. Cancer 128, 2911-2922.
    • (2011) Int. J. Cancer , vol.128 , pp. 2911-2922
    • Schmiedel, B.J.1    Arélin, V.2    Gruenebach, E.3    Krusch, M.4    Schmidt, S.M.5    Salih, H.R.6
  • 70
    • 53949108746 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cells
    • Schmudde, M., Braun, A., Pende, D., Sonnemann, J., Klier, U., Beck, J. E, et al. (2008). Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cells. Cancer Lett. 272, 110-121.
    • (2008) Cancer Lett , vol.272 , pp. 110-121
    • Schmudde, M.1    Braun, A.2    Pende, D.3    Sonnemann, J.4    Klier, U.5    Beck, J.E.6
  • 71
    • 15244351682 scopus 로고    scopus 로고
    • Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner
    • Seggewiss, R., Loré, K., Greiner, E., Magnusson, M. K., Price, D. A., Douek, D. C., et al. (2005). Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. Blood 105, 2473-2479.
    • (2005) Blood , vol.105 , pp. 2473-2479
    • Seggewiss, R.1    Loré, K.2    Greiner, E.3    Magnusson, M.K.4    Price, D.A.5    Douek, D.C.6
  • 72
    • 38949113714 scopus 로고    scopus 로고
    • Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma
    • Shi, J., Tricot, G. J., Malaviarachchi, P. A., Szmania, S. M., Kellum, R. E., Storrie, B., et al. (2008). Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma. Blood 111, 1309-1317.
    • (2008) Blood , vol.111 , pp. 1309-1317
    • Shi, J.1    Tricot, G.J.2    Malaviarachchi, P.A.3    Szmania, S.M.4    Kellum, R.E.5    Storrie, B.6
  • 73
    • 28244502269 scopus 로고    scopus 로고
    • Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A andB
    • Skov, S., Pedersen, M. T., Andresen, L., Straten, P. T., Woetmann, A., Odum, N., et al. (2005). Cancer cells become susceptible to natural killer cell killing after exposure to histone deacetylase inhibitors due to glycogen synthase kinase-3-dependent expression of MHC class I-related chain A andB. Cancer Res. 65, 11136-11145.
    • (2005) Cancer Res , vol.65 , pp. 11136-11145
    • Skov, S.1    Pedersen, M.T.2    Andresen, L.3    Straten, P.T.4    Woetmann, A.5    Odum, N.6
  • 74
    • 65349131915 scopus 로고    scopus 로고
    • ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype
    • Soriani, A., Zingoni, A., Cerboni, C., Iannitto, M. L., Ricciardi, M. R., Di Gialleonardo, V., et al. (2009). ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype. Blood 113, 3503-3511.
    • (2009) Blood , vol.113 , pp. 3503-3511
    • Soriani, A.1    Zingoni, A.2    Cerboni, C.3    Iannitto, M.L.4    Ricciardi, M.R.5    Di Gialleonardo, V.6
  • 76
    • 29244488561 scopus 로고    scopus 로고
    • Immunomodulatory drug lenalidomide (CC-5013 IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: clinical implications
    • Tai, Y T., Li, X. F., Catley, L., Coffey, R., Breitkreutz, I., Bae, J., et al. (2005). Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: clinical implications. Cancer Res. 65, 11712-11720.
    • (2005) Cancer Res , vol.65 , pp. 11712-11720
    • Tai, Y.T.1    Li, X.F.2    Catley, L.3    Coffey, R.4    Breitkreutz, I.5    Bae, J.6
  • 77
    • 32244445715 scopus 로고    scopus 로고
    • A novel dendritic cell subset involved in tumor immuno-surveillance
    • Taieb, J., Chaput, N., Ménard, C., Apetoh, L., Ullrich, E., Bonmort, M., et al. (2006). A novel dendritic cell subset involved in tumor immuno-surveillance. Nat. Med. 12, 214-219.
    • (2006) Nat. Med. , vol.12 , pp. 214-219
    • Taieb, J.1    Chaput, N.2    Ménard, C.3    Apetoh, L.4    Ullrich, E.5    Bonmort, M.6
  • 78
    • 84867023568 scopus 로고    scopus 로고
    • Rapid and sustained increase of large granular lymphocytes and rare cytomegalovirus reactivation during dasatinib treatment in chronic myelogenous leukemia patients
    • Tanaka, H., Nakashima, S., and Usuda, M. (2012). Rapid and sustained increase of large granular lymphocytes and rare cytomegalovirus reactivation during dasatinib treatment in chronic myelogenous leukemia patients. Int. J. Hematol. 308-319.
    • (2012) Int. J. Hematol. , pp. 308-319
    • Tanaka, H.1    Nakashima, S.2    Usuda, M.3
  • 81
    • 42449123606 scopus 로고    scopus 로고
    • Natural killer cell-directed therapies: moving from unexpected results to successful strategies
    • Terme, M., Ullrich, E., Delahaye, N. F., Chaput, N., and Zitvogel, L. (2008). Natural killer cell-directed therapies: moving from unexpected results to successful strategies. Nat. Immunol. 9, 486-494.
    • (2008) Nat. Immunol. , vol.9 , pp. 486-494
    • Terme, M.1    Ullrich, E.2    Delahaye, N.F.3    Chaput, N.4    Zitvogel, L.5
  • 82
    • 40449129958 scopus 로고    scopus 로고
    • Selective induction of expression of a ligand for the NKG2D receptor by proteasome inhibitors
    • Vales-Gomez, M., Chisholm, S. E., Cassady-Cain, R. L., Roda-Navarro, P., and Reyburn, H. T. (2008). Selective induction of expression of a ligand for the NKG2D receptor by proteasome inhibitors. Cancer Res. 68, 1546-1554.
    • (2008) Cancer Res , vol.68 , pp. 1546-1554
    • Vales-Gomez, M.1    Chisholm, S.E.2    Cassady-Cain, R.L.3    Roda-Navarro, P.4    Reyburn, H.T.5
  • 84
    • 33144469102 scopus 로고    scopus 로고
    • The proteasome and pro-teasome inhibitors in cancer therapy
    • Voorhees, P. M., and Orlowski, R. Z. (2006). The proteasome and pro-teasome inhibitors in cancer therapy. Annu. Rev. Pharmacol Toxicol. 46, 189-213.
    • (2006) Annu. Rev. Pharmacol Toxicol. , vol.46 , pp. 189-213
    • Voorhees, P.M.1    Orlowski, R.Z.2
  • 85
    • 66349096076 scopus 로고    scopus 로고
    • Proteasome inhibition induces apoptosis in primary human natural killer cells and suppresses NKp46-mediated cytotoxic-ity
    • Wang, X., Ottosson, A., Ji, C., Feng, X., Nordenskjöld, M., Henter, J. I., et al. (2009). Proteasome inhibition induces apoptosis in primary human natural killer cells and suppresses NKp46-mediated cytotoxic-ity. Haematologica 94, 470-478.
    • (2009) Haematologica , vol.94 , pp. 470-478
    • Wang, X.1    Ottosson, A.2    Ji, C.3    Feng, X.4    Nordenskjöld, M.5    Henter, J.I.6
  • 87
    • 77958180004 scopus 로고    scopus 로고
    • Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2'-deoxycytidine
    • Wu, J. F., Zeng, G. L., Shen, W., Yang, M., Wang, F., Tian, L., et al. (2009). Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2'-deoxycytidine. Zhonghua Gan Zang Bing Za Zhi 17, 675-678.
    • (2009) Zhonghua Gan Zang Bing Za Zhi , vol.17 , pp. 675-678
    • Wu, J.F.1    Zeng, G.L.2    Shen, W.3    Yang, M.4    Wang, F.5    Tian, L.6
  • 88
    • 59649118271 scopus 로고    scopus 로고
    • Primitive quiescent CD34+ cells in chronic myeloid leukemia are targeted by in vitro expanded natural killer cells, which are functionally enhanced by bortezomib
    • Yong, A. S., Keyvanfar, K., Hensel, N., Eniafe, R., Savani, B. N., Berg, M., et al. (2009). Primitive quiescent CD34+ cells in chronic myeloid leukemia are targeted by in vitro expanded natural killer cells, which are functionally enhanced by bortezomib. Blood 113, 875-882.
    • (2009) Blood , vol.113 , pp. 875-882
    • Yong, A.S.1    Keyvanfar, K.2    Hensel, N.3    Eniafe, R.4    Savani, B.N.5    Berg, M.6
  • 89
    • 67349128297 scopus 로고    scopus 로고
    • Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysis
    • Zhang, C., Wang, Y., Zhou, Z., Zhang, J., and Tian, Z. (2009). Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysis. Cancer Immunol Immunother. 58, 1275-1285.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1275-1285
    • Zhang, C.1    Wang, Y.2    Zhou, Z.3    Zhang, J.4    Tian, Z.5
  • 90
    • 52549088421 scopus 로고    scopus 로고
    • Immunomodu-latory drugs Revlimid (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation
    • Zhu, D., Corral, L. G., Fleming, Y W., and Stein, B. (2008). Immunomodu-latory drugs Revlimid (lenalidomide) and CC-4047 induce apoptosis of both hematological and solid tumor cells through NK cell activation. Cancer Immunol Immunother. 57, 1849-1859.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1849-1859
    • Zhu, D.1    Corral, L.G.2    Fleming, Y.W.3    Stein, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.