Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysis

Cancer Immunology, Immunotherapy

Volumn 58, Issue 8, 2009, Pages 1275-1285

  Zhang, Cai ^a   Wang, Yiping ^a   Zhou, Zhixia ^a   Zhang, Jian ^a   Tian, Zhigang ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

HDAC inhibitor; NKG2D; NKG2D ligand; Sodium butyrate; Transcription factor

Indexed keywords

BUTYRIC ACID; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; HISTONE DEACETYLASE INHIBITOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS I RELATED CHAIN MOLECULE A; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS I RELATED CHAIN MOLECULE B; MESSENGER RNA; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2D; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ARTICLE; CELL INTERACTION; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOLYSIS; HELA CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LIGAND BINDING; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BUTYRATES; CELL LINE, TUMOR; CYTOTOXICITY, IMMUNOLOGIC; DNA-BINDING PROTEINS; ENZYME INHIBITORS; HELA CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTONE DEACETYLASES; HSP70 HEAT-SHOCK PROTEINS; HUMANS; KILLER CELLS, NATURAL; NEOPLASMS; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING; SP1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; UP-REGULATION; VALPROIC ACID;

EID: 67349128297     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-008-0645-8     Document Type: Article

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