Visualizing brain inflammation with a shingled-leg radio-frequency head probe for 19F/1H MRI

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Waiczies, Helmar ^a   Lepore, Stefano ^a   Drechsler, Susanne ^a   Qadri, Fatimunnisa ^a   Purfürst, Bettina ^a   Sydow, Karl ^b   Dathe, Margitta ^b   Kühne, André ^c   Lindel, Tomasz ^c   Hoffmann, Werner ^c   Pohlmann, Andreas ^a   Niendorf, Thoralf ^a   Waiczies, Sonia ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^c PHYSIKALISCH TECHNISCHE BUNDESANSTALT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSTIC AGENT; FLUORINE; NANOPARTICLE; PROTON;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL; ARTICLE; BRAIN; CYTOLOGY; EQUIPMENT; EQUIPMENT DESIGN; METHODOLOGY; MOUSE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY;

ANIMALS; BRAIN; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; EQUIPMENT DESIGN; FLUORINE; MAGNETIC RESONANCE IMAGING; MICE; NANOPARTICLES; NEUROIMAGING; PROTONS;

MLCS; MLOWN;

EID: 84874292174     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep01280     Document Type: Article

References (37)

1. Charil, A. & Filippi, M. Inflammatory demyelination and neurodegeneration in early multiple sclerosis. J. Neurol. Sci. 259, 7-15 (2007).
2. Trapp, B. D. & Nave, K.-A. Multiple sclerosis: an immune or neurodegenerative disorder? Annu. Rev. Neurosci. 31, 247-69 (2008).
3. Stadelmann, C. Multiple sclerosis as a neurodegenerative disease: pathology, mechanisms and therapeutic implications. Curr. Opin. Neurol. 24, 224-9 (2011).
4. Dousset, V., Gomez, C., Petry, K. G., Delalande, C. & Caille, J. M. Dose and scanning delay using USPIO for central nervous system macrophage imaging. Magma 8, 185-9 (1999).
5. Floris, S. et al. Blood-brain barrier permeability and monocyte infiltration in experimental allergic encephalomyelitis: a quantitative MRI study. Brain 127, 616-27 (2004).
6. Tysiak, E. et al. Beyond blood brain barrier breakdown-in vivo detection of occult neuroinflammatory foci by magnetic nanoparticles in high field MRI. J. Neuroinflamm. 6, 20 (2009).
7. Oude Engberink, R. D. et al. Dynamics and fate of USPIO in the central nervous system in experimental autoimmune encephalomyelitis. NMR Biomed. 23, 1087-96 (2010).
8. Ruiz-Cabello, J., Barnett, B. P., Bottomley, P. a. & Bulte, J. W. M. Fluorine ((19)F) MRS and MRI in biomedicine. NMR Biomed. (2010).
9. Hoult, D. & Richards, R. The signal-to-noise ratio of the nuclear magnetic resonance experiment. J. Magn. Reson. 24, 71-85 (1976).
10. Wong Ernest, W. H. Millipede Coils. Encycl. Magn. Reson. (2007).
11. Tomanek, B., Volotovskyy, V., Gruwel, M. L. H., McKenzie, E. & King, S. B. Double-frequency birdcage volume coils for 4.7T and 7T. Concept. Magn. Reson. B 26B, 16-22 (2005).
12. Waiczies, H. et al. Identification of Cellular Infiltrates during Early Stages of Brain Inflammation with Magnetic Resonance Microscopy. PLoS ONE7, e32796 (2012).
13. Hornak, J.P., Szumowski, J. & Bryant, R.G. Magnetic field mapping. Magn. Reson. Med. 6, 158-63 (1988).
14. Dowell, N. G. & Tofts, P. S. Fast, accurate, and precise mapping of the RF field in vivo using the 180 degrees signal null. Magn. Reson. Med. 58, 622-30 (2007).
15. Holland, G. N. & Hinshaw, P. A. B. W. S. Communications 19F Magnetic Resonance Imaging. J. Magn. Reson. 136, 133-136 (1977).
16. Liu, M. S. & Long, D. M. Perfluoroctylbromide as adiagnostic contrast medium in gastroenterography. Radiology 122, 71-6 (1977).
17. Ahrens, E. T., Flores, R., Xu, H. & Morel, P. a In vivo imaging platform for tracking immunotherapeutic cells. Nat. Biotechnol. 23, 983-7 (2005).
18. Srinivas, M., Morel, P. a., Ernst, L. A., Laidlaw, D. H. & Ahrens, E. T. Fluorine-19 MRI for visualization and quantification of cell migration in a diabetes model. Magn. Reson. Med. 58, 725-34 (2007).
19. Partlow, K. C. et al. 19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons. FASEB J. 21, 1647-54 (2007).
20. Srinivas, M. et al. In vivo cytometry of antigen-specific t cells using 19F MRI. Magn. Reson. Med. 62, 747-53 (2009).
21. Waiczies, H. et al. Perfluorocarbon particle size influences magnetic resonance signal and immunological properties of dendritic cells. PloS one 6, e21981 (2011).
22. Srinivas, M., Boehm-Sturm, P., Figdor, C. G., De Vries, I. J. & Hoehn, M. Labeling cells for in vivo tracking using 19F MRI. Biomaterials (2012).
23. Doty, F. D., Entzminger, G., Kulkarni, J., Pamarthy, K. & Staab, J. P. Radio frequency coil technology for small-animal MRI. NMR Biomed. 20, 304-25 (2007).
24. Hill, H. D. W. & Richards, R. E. Limits of measurement in magnetic resonance. J. Phys. E Sci. Instrum. 1, 977-983 (1968).
25. Crozier, S., Luescher, K., Forbes, L. K. & Doddrell, D. M. Optimized Small-Bore, High-Pass Resonator Designs. Magn. Reson. Med., Series B 109, 1-11 (1995).
26. Mispelter, J. & Lupu, M. Homogeneous resonators for magnetic resonance: A review. C. R. Chim. 11, 340-355 (2008).
27. Giovannetti, G., Hartwig, V., Landini, L. & Santarelli, M. F. Low-Field MR Coils: Comparison between Strip and Wire Conductors. Appl. Magn. Reson. 39, 391-399 (2010).
28. Shen, G. X., Wu, J. F., Boada, F. E. & Thulborn, K. R. Experimentally verified, theoretical design of dual-tuned, low-pass birdcage radiofrequency resonators for magnetic resonance imaging and magnetic resonance spectroscopy of human brain at 3.0 Tesla. Magn. Reson. Med. 41, 268-75 (1999).
29. Hu, L. et al. A generalized strategy for designing (19)F/(1)H dual-frequency MRI coil for small animal imaging at 4.7Tesla. J. Magn. Reson. Im. 34, 245-52 (2011).
30. Phillips, M. J., Needham, M. & Weller, R. O. Role of cervical lymph nodes in autoimmune encephalomyelitis in the Lewis rat. J. Pathol. 182, 457-64 (1997).
31. Kaminski, M. et al. Migration of monocytes after intracerebral injection at entorhinal cortex lesion site. J. Leukocyte. Biol. 92, 31-9 (2012).
32. Laman, J. D. & Weller, R. O. Editorial: route by which monocytes leave the brain is revealed. J. Leukocyte. Biol. 92, 6-9 (2012).
33. Chin, C.-L., Collins, C. M., Li, S., Dardzinski, B. J. & Smith, M. B. BirdcageBuilder: Design of specified-geometry birdcage coils with desired current pattern and resonant frequency. Concept. Magnetic. Res. 15, 156-163 (2002).
34. Jiru, F. & Klose, U. Fast 3D radiofrequency field mapping using echo-planar imaging. Magn. Reson. Med. 56, 1375-9 (2006).
35. Seifert, F., Wübbeler, G., Junge, S., Ittermann, B. & Rinneberg, H. Patient safety concept for multichannel transmit coils. J. Magn. Reson. Im. 26, 1315-21 (2007).
36. Bendix, I. et al. MAPK3 deficiency drives autoimmunity via DC arming. Eur. J. Immunol. 40, 1486-95 (2010).
37. Gruetter, R. Automatic, localizedin Vivo adjustment of all first-and second-order shim coils. Magn. Reson. Med. 29, 804-811 (1993).