Dose and scanning delay using USPIO for central nervous system macrophage imaging

Magnetic Resonance Materials in Physics, Biology and Medicine

Volumn 8, Issue 3, 1999, Pages 185-189

  Dousset, Vincent ^a   Gomez, Christophe ^a   Petry, Klaus G ^b   Delalande, Christophe ^a   Caille, Jean Marie ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b INSERM   (France)

Author keywords

Allergic encephalomyelitis; Contrast agents; Macrophages; MRI

Indexed keywords

CONTRAST MEDIUM; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL TISSUE; CENTRAL NERVOUS SYSTEM; CONFERENCE PAPER; CONTROLLED STUDY; DIAGNOSTIC IMAGING; IMAGE ANALYSIS; MACROPHAGE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN STEM; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTRAST MEDIA; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GUINEA PIGS; HUMANS; IMAGE ENHANCEMENT; INJECTIONS, INTRAVENOUS; IRON; MACROPHAGES; MAGNETIC RESONANCE IMAGING; OXIDES; RATS; RATS, INBRED LEW;

ANIMALIA;

EID: 0032852425     PISSN: 13528661     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1352-8661(99)00028-9     Document Type: Conference Paper

References (14)

1. Weissleder R., Elizondo G., Wittenberg J., Lee A.S., Josephson L., Brady T.J. Ultrasmall superparamagnetic iron oxide: characterization of a new class contrast agents for MR imaging. Radiology. 175:1990;494-498.
2. Weissleder R., Cheng H.-C., Bogdanova A., Bogdanov A. Jr Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging. 7:1997;258-263.
3. Anzai Y., Blackwell K.E., Hirschowitz S.L., Rogers J.W., Sato Y., Yuh W.T.C., Runge V.M., Morris M.R., McLachan S.J., Lufkin R.B. Initial clinical experience with dextran-coated superparamagnetic iron oxide for detection of lymph node metastases in patients with head and neck cancer. Radiology. 192:1994;709-715.
4. Dousset V, Delalande C, Ballarino L, et al. In vivo macrophage activity imaging in the central nervous system detected by magnetic resonance. Magn Reson Med 1999;41:329-333.
5. Coyle P.K. The neuroimmunology of multiple sclerosis. Adv Neuroimmunol. 6:1996;143-154.
6. Batholdi D., Suchwab M.E. Methylprednisolone inhibits early inflammatory processes but not ischemic cell death after experimental cord lesion in rat. Brain Res. 672:1995;177-186.
7. Dubois-Dalcq M., Altmeyer R., Chiron M., Wilt S. HIV interactions with cells of the nervous system. Curr Opin Neurobiol. 5:1995;647-655.
8. Martin R., McFarland H. Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis. Crit Rev Clin Lab Sci. 32:1995;121-182.
9. Rossi M.L., Jones N.R., Candy E. et al. The mononuclear cell infiltrate compared with survival in high grade astrocytomas. Acta Neuropathol (Berlin). 78:1989;189-193.
10. Polman C.H., Dijkstra C.D., Sminia T., Koetsier J.C. Immunohistological analysis of the central nervous system of Lewis rats with experimental allergic encephalomyelitis. J Neuroimmunol. 11:1986;215-222.
11. Bauer J., Huitinga I., Zhao W., Lassmann H., Hickey W.F., Dijkstra C.D. The role of macrophages, perivascular cells, and microglia cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia. 15:1995;437-446.
12. Raine C.S. Multiple sclerosis: immune system molecule expression in the central nervous system. J Neuropathol Exp Neurol. 53:1994;328-337.
13. Chambon C., Clément O., Le Blanche A., Schouman-Claeys E., Frija G. Superparamagnetic iron oxides as positive MR contrast agents in vitro and in vivo. Magn Reson Imaging. 11:1993;509-519.
14. Guimareas R., Clément O., Bittoun J., Carnot F., Frija G. MR lymphography with superparamagnetic iron nanoparticles in rats: pathologic basis for contrast enhancement. AJR. 162:1994;201-207.