Polarization of Diploid Daughter Cells Directed by Spatial Cues and GTP Hydrolysis of Cdc42 in Budding Yeast

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Lo, Wing Cheong ^a   Lee, Mid Eum ^a   Narayan, Monisha ^a   Chou, Ching Shan ^a   Park, Hay Oak ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE; PROTEIN CDC42; PROTEIN RGA1; UNCLASSIFIED DRUG;

ARTICLE; BUDDING; CELL CYCLE M PHASE; CELL POLARITY; CELL TYPE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINESIS; DAUGHTER CELL; DIPLOIDY; DYNAMICS; HYDROLYSIS; LIVE CELL; MATHEMATICAL MODEL; NOISE; NONHUMAN; POLARIZATION; YEAST;

CDC42 GTP-BINDING PROTEIN, SACCHAROMYCES CEREVISIAE; CELL DIVISION; CELL POLARITY; DIPLOIDY; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; MODELS, THEORETICAL; SACCHAROMYCES CEREVISIAE;

EID: 84874262500     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056665     Document Type: Article

References (54)

1. Etienne-Manneville S, (2004) Cdc42- the centre of polarity. J Cell Sci 117: 1291-1300.
2. Park H-O, Bi E, (2007) Central roles of small GTPases in the development of cell polarity in yeast and beyond. Microbiol Mol Biol Rev 71: 48-96.
3. Chant J, Herskowitz I, (1991) Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway. Cell 65: 1203-1212.
4. Chant J, Pringle JR, (1995) Patterns of bud-site selection in the yeast Saccharomyces cerevisiae. J Cell Biol 129: 751-765.
5. Freifelder D, (1960) Bud position in Saccharomyces cerevisiae. J Bacteriol 80: 567-568.
6. Hicks JB, Strathern JN, Herskowitz I, (1977) Interconversion of yeast mating types III. Action of the homothallism (HO) gene in cells homozygous for the mating type locus. Genetics 85: 395-405.
7. Bender A, Pringle JR, (1989) Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1. Proc Natl Acad Sci USA 86: 9976-9980.
8. Chant J, Corrado K, Pringle JR, Herskowitz I, (1991) Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1. Cell 65: 1213-1224.
9. Powers S, Gonzales E, Christensen T, Cubert J, Broek D, (1991) Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant. Cell 65: 1225-1231.
10. Park H-O, Chant J, Herskowitz I, (1993) BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast. Nature 365: 269-274.
11. Bender A, (1993) Genetic evidence for the roles of the bud-site-selection genes BUD5 and BUD2 in control of the Rsr1p (Bud1p) GTPase in yeast. Proc Natl Acad Sci, U S A 90: 9926-9929.
12. Zahner JE, Harkins HA, Pringle JR, (1996) Genetic analysis of the bipolar pattern of bud-site selection in the yeast Saccharomyces cerevisiae. Mol Cell Biol 16: 1857-1870.
13. Ni L, Snyder M, (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12: 2147-2170.
14. Sheu YJ, Barral Y, Snyder M, (2000) Polarized growth controls cell shape and bipolar bud site selection in Saccharomyces cerevisiae. Mol Cell Biol 20: 5235-5247.
15. Yang S, Ayscough KR, Drubin DG, (1997) A role for the actin cytoskeleton of Saccharomyces cerevisiae in bipolar bud-site selection. J Cell Biol 136: 111-123.
16. Schenkman LR, Caruso C, Pagé N, Pringle JR, (2002) The role of cell cycle-regulated expression in the localization of spatial landmark proteins in yeast. J Cell Biol 156: 829-841.
17. Chen T, Hiroko T, Chaudhuri A, Inose F, Lord M, et al. (2000) Multigenerational cortical inheritance of the Rax2 protein in orienting polarity and division in yeast. Science 290: 1975-1978.
18. Fujita A, Lord M, Hiroko T, Hiroko F, Chen T, et al. (2004) Rax1, a protein required for the establishment of the bipolar budding pattern in yeast. Gene 327: 161-169.
19. Kang PJ, Angerman E, Nakashima K, Pringle JR, Park H-O, (2004) Interactions among Rax1p, Rax2p, Bud8p, and Bud9p in marking cortical sites for bipolar bud-site selection in yeast. Mol Biol Cell 15: 5145-5157.
20. Harkins HA, Pagé N, Schenkman LR, De Virgilio C, Shaw S, et al. (2001) Bud8p and Bud9p, proteins that may mark the sites for bipolar budding in yeast. Mol Biol Cell 12: 2497-2518.
21. Wedlich-Soldner R, Altschler S, Wu L, Li R, (2003) Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase. Science 299: 1231-1235.
22. Irazoqui JE, Gladfelter AS, Lew DJ, (2003) Scaffold-mediated symmetry breaking by Cdc42p. Nat Cell Biol 5: 1062-1070.
23. Wedlich-Soldner R, Wai SC, Schmidt T, Li R, (2004) Robust cell polarity is a dynamic state established by coupling transport and GTPase signaling. J Cell Biol 166: 889-900.
24. Kozubowski L, Saito K, Johnson JM, Howell AS, Zyla TR, et al. (2008) Symmetry-breaking polarization driven by a Cdc42p GEF-PAK complex. Curr Biol 18: 1719-1726.
25. Ozbudak EM, Becskei A, van Oudenaarden A, (2005) A system of counteracting feedback loops regulates Cdc42p activity during spontaneous cell polarization. Dev Cell 9: 565-571.
26. Marco E, Wedlich-Soldner R, Li R, Altschuler SJ, Wu LF, (2007) Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity. Cell 129: 411-422.
27. Slaughter BD, Das A, Schwartz JW, Rubinstein B, Li R, (2009) Dual modes of cdc42 recycling fine-tune polarized morphogenesis. Dev Cell 17: 823-835.
28. Howell AS, Jin M, Wu CF, Zyla TR, Elston TC, et al. (2012) Negative feedback enhances robustness in the yeast polarity establishment circuit. Cell 149: 322-333.
29. Altschuler SJ, Angenent SB, Wang Y, Wu LF, (2008) On the spontaneous emergence of cell polarity. Nature 454: 886-889.
30. Goryachev AB, Pokhilko AV, (2008) Dynamics of Cdc42 network embodies a Turing-type mechanism of yeast cell polarity. FEBS Letters 582: 1437-1443.
31. Johnson JM, Jin M, Lew DJ, (2011) Symmetry breaking and the establishment of cell polarity in budding yeast. Curr Opin Genet Dev 21: 740-746.
32. Layton AT, Savage NS, Howell AS, Carroll SY, Drubin DG, et al. (2011) Modeling vesicle traffic reveals unexpected consequences for Cdc42p-mediated polarity establishment. Curr Biol 21: 184-194.
33. Arkowitz RA, Bassilana M, (2011) Polarized growth in fungi: symmetry breaking and hyphal formation. Semin Cell Dev Biol 22: 806-815.
34. Tong Z, Gao X-D, Howell AS, Bose I, Lew DJ, et al. (2007) Adjacent positioning of cellular structures enabled by a Cdc42 GTPase-activating protein mediated zone of inhibition. J Cell Biol 179: 1375-1384.
35. Richman TJ, Sawyer MM, Johnson DI, (2002) Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth. Eukaryot Cell 1: 458-468.
36. Caviston JP, Longtine M, Pringle JR, Bi E, (2003) The role of Cdc42p GTPase-activating proteins in assembly of the septin ring in yeast. Mol Biol Cell 14: 4051-4066.
37. Knaus M, Pelli-Gulli M-P, van Drogen F, Springer S, Jaquenoud M, et al. (2007) Phosphorylation of Bem2p and Bem3p may contribute to local activation of Cdc42p at bud emergence. EMBO J 26: 4501-4513.
38. Sopko R, Huang D, Smith JC, Figeys D, Andrews BJ, (2007) Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. EMBO J 26: 4487-4500.
39. Kozminski KG, Beven L, Angerman E, Tong AHY, Boone C, et al. (2003) Interaction between a Ras and a Rho GTPase couples selection of a growth site to the development of cell polarity in yeast. Mol Biol Cell 14: 4958-4970.
40. Zheng Y, Hart MJ, Shinjo K, Evans T, Bender A, et al. (1993) Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain. J Biol Chem 268: 24629-24634.
41. Zheng Y, Cerione R, Bender A, (1994) Control of the yeast bud-site assembly GTPase Cdc42: catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3. J Biol Chem 269: 2369-2372.
42. Marquitz AR, Harrison JC, Bose I, Zyla TR, McMillan JN, et al. (2002) The Rho-GAP Bem2p plays a GAP-independent role in the morphogenesis checkpoint. EMBO J 21: 4012-4025.
43. Bacon JS, Davidson ED, Jones D, Taylor IF, (1966) The location of chitin in the yeast cell wall. Biochem J 101: 36C-38C.
44. Frydlová I, Malcová I, Vasicová P, Hasek J, (2009) Deregulation of DSE1 gene expression results in aberrant budding within the birth scar and cell wall integrity pathway activation in Saccharomyces cerevisiae. Eukaryot Cell 8: 586-594.
45. Cullen PJ, Sprague GF Jr, (2002) The roles of bud-site-selection proteins during haploid invasive growth in yeast. Mol Biol Cell 13: 2990-3004.
46. Howell AS, Lew DJ, (2012) Morphogenesis and the cell cycle. Genetics 190: 51-77.
47. Smith GR, Givan SA, Cullen P, Sprague GF Jr, (2002) GTPase-activating proteins for Cdc42. Eukaryotic Cell 1: 469-480.
48. Chen GC, Zheng L, Chan CS, (1996) The LIM domain-containing Dbm1 GTPase-activating protein is required for normal cellular morphogenesis in Saccharomyces cerevisiae. Mol Cell Biol 16: 1376-1390.
49. Stevenson BJ, Ferguson B, De Virgilio C, Bi E, Pringle JR, et al. (1995) Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae. Genes & Dev 9: 2949-2963.
50. Watanabe M, Watanabe D, Nogami S, Morishita S, Ohya Y, (2009) Comprehensive and quantitative analysis of yeast deletion mutants defective in apical and isotropic bud growth. Curr Genet 55: 365-380.
51. Taheri N, Köhler T, Braus GH, Mösch H-U, (2000) Asymmetrically localized Bud8p and Bud9p proteins control yeast cell polarity and development. EMBO J 19: 6686-6696.
52. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, et al. (1999) Current Protocols in Molecular Biology: John Wiley & Sons, Inc.
53. Guthrie C, Fink GR (1991) Guide to Yeast Genetics and Molecular Biology. San Diego: Academic Press. 933 p.
54. Bi E, Pringle JR, (1996) ZDS1 and ZDS2, genes whose products may regulate Cdc42p in Saccharomyces cerevisiae. Mol Cell Biol 16: 5264-5275.