S-nitrosoglutathione reductase (GSNOR) enhances vasculogenesis by mesenchymal stem cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages 2834-2839

  Gomes, Samirah A ^a   Rangel, Erika B ^a   Premer, Courtney ^a   Dulce, Raul A ^a   Cao, Yenong ^a   Florea, Victoria ^a   Balkan, Wayne ^a   Rodrigues, Claudia O ^a   Schally, Andrew V ^a,b   Hare, Joshua M ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Angiogenesis; Nitroso redox imbalance

Indexed keywords

5' NUCLEOTIDASE; ENDOGLIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GROWTH HORMONE RELEASING FACTOR RECEPTOR; MATRIGEL; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; S NITROSOGLUTATHIONE; S NITROSOGLUTATHIONE REDUCTASE; S NITROSOTHIOL; STEM CELL ANTIGEN 1; THY 1 ANTIGEN; UNCLASSIFIED DRUG; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CAPILLARY TUBE; CELL ASSAY; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIAL PROGENITOR CELL; HEMATOPOIETIC STEM CELL; HOMOZYGOTE; HUMAN; HUMAN CELL; HYPOTHESIS; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MOLECULAR WEIGHT; MOUSE; NITROSYLATION; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WESTERN BLOTTING;

HYDROGEN-ION CONCENTRATION;

EID: 84874233217     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1220185110     Document Type: Article

References (37)

1. Asahara T, et al. (1997) Isolation of putative progenitor endothelial cells for angio-genesis. Science 275 (5302):964-967.
2. Murohara T, et al. (1998) Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest 101 (11):2567-2578.
3. Aicher A, et al. (2009) cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis. PLoS ONE 4 (3):e4879.
4. Aicher A, et al. (2003) Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med 9 (11):1370-1376.
5. Asahara T, et al. (1999) Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 85 (3):221-228.
6. Ferrara N, Gerber HP, LeCouter J (2003) The biology of VEGF and its receptors. Nat Med 9 (6):669-676.
7. Coultas L, Chawengsaksophak K, Rossant J (2005) Endothelial cells and VEGF in vascular development. Nature 438 (7070):937-945.
8. Nagaya N, et al. (2004) Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis. Am J Physiol Heart Circ Physiol 287 (6):H2670-H2676.
9. Bautch VL (2011) Stem cells and the vasculature. Nat Med 17 (11):1437-1443.
10. Caplan AI (2008) All MSCs are pericytes? Cell Stem Cell 3 (3):229-230.
11. Chen J, et al. (2003) Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ Res 92 (6):692-699.
12. Quevedo HC, et al. (2009) Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity. Proc Natl Acad Sci USA 106 (33):14022-14027.
13. Williams AR, et al. (2011) Intramyocardial stem cell injection in patients with ischemic cardiomyopathy: Functional recovery and reverse remodeling. Circ Res 108 (7):792-796.
14. Oswald J, et al. (2004) Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 22 (3):377-384.
15. Sun B, et al. (2005) Correlation between melanoma angiogenesis and the mesen-chymal stem cells and endothelial progenitor cells derived from bone marrow. Stem Cells Dev 14 (3):292-298.
16. Ball SG, Shuttleworth CA, Kielty CM (2007) Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol 177 (3):489-500.
17. Liu L, et al. (2001) A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. Nature 410 (6827):490-494.
18. Liu L, et al. (2004) Essential roles of S-nitrosothiols in vascular homeostasis and en-dotoxic shock. Cell 116 (4):617-628.
19. Beitz JG, Kim IS, Calabresi P, Frackelton AR, Jr. (1991) Human microvascular endo-thelial cells express receptors for platelet-derived growth factor. Proc Natl Acad Sci USA 88 (5):2021-2025.
20. Izdebski J, et al. (1995) Synthesis and biological evaluation of superactive agonists of growth hormone-releasing hormone. Proc Natl Acad Sci USA 92 (11):4872-4876.
21. Beigi F, et al. (2012) Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function. Proc Natl Acad Sci USA 109 (11):4314-4319.
22. Lima B, et al. (2009) Endogenous S-nitrosothiols protect against myocardial injury. Proc Natl Acad Sci USA 106 (15):6297-6302.
23. Anand P, Stamler JS (2012) Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease. J Mol Med (Berl) 90 (3):233-244.
24. Ball SG, Shuttleworth CA, Kielty CM (2007) Mesenchymal stem cells and neo-vascularization: Role of platelet-derived growth factor receptors. J Cell Mol Med 11 (5):1012-1030.
25. Ball SG, Shuttleworth CA, Kielty CM (2010) Platelet-derived growth factor receptors regulate mesenchymal stem cell fate: Implications for neovascularization. Expert Opin Biol Ther 10 (1):57-71.
26. Wu X, et al. (2005) Mesenchymal stem cells participating in ex vivo endothelium repair and its effect on vascular smooth muscle cells growth. Int J Cardiol 105 (3):274-282.
27. Hall AP (2006) Review of the pericyte during angiogenesis and its role in cancer and diabetic retinopathy. Toxicol Pathol 34 (6):763-775.
28. Kanashiro-Takeuchi RM, et al. (2012) Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI). Proc Natl Acad Sci USA 109 (2):559-563.
29. Kanashiro-Takeuchi RM, et al. (2010) Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction. Proc Natl Acad Sci USA 107 (6):2604-2609.
30. Dioufa N, et al. (2010) Acceleration of wound healing by growth hormone-releasing hormone and its agonists. Proc Natl Acad Sci USA 107 (43):18611-18615.
31. Ludwig B, et al. (2010) Agonist of growth hormone-releasing hormone as a potential effector for survival and proliferation of pancreatic islets. Proc Natl Acad Sci USA 107 (28):12623-12628.
32. Wang Y, et al. (2008) Nitric oxide suppresses the secretion of vascular endothelial growth factor and hepatocyte growth factor from human mesenchymal stem cells. Shock 30 (5):527-531.
33. Cipriani P, et al. (2007) Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: New insight into the pathogenesis of systemic sclerosis. Arthritis Rheum 56 (6):1994-2004.
34. Hare JM (2004) Nitroso-redox balance in the cardiovascular system. N Engl J Med 351 (20):2112-2114.
35. Kuhlencordt PJ, et al. (2004) Role of endothelial nitric oxide synthase in endothelial activation: Insights from eNOS knockout endothelial cells. Am J Physiol Cell Physiol 286 (5):C1195-C1202.
36. Huang PL (2003) Endothelial nitric oxide synthase and endothelial dysfunction. Curr Hypertens Rep 5 (6):473-480.
37. Gupta TK, Toruner M, Chung MK, Groszmann RJ (1998) Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats. Hepatology 28 (4):926-931.