Purification and characterization of an antitumor polysaccharide from Portulaca oleracea L.

Carbohydrate Polymers

Volumn 93, Issue 2, 2013, Pages 395-400

  Shen, Huan ^a   Tang, Guo ^b   Zeng, Guang ^c   Yang, Yongjin ^a   Cai, Xingwei ^a   Li, Dongli ^a   Liu, Hongchen ^b   Zhou, Ningxin ^a  

^a General Hospital of the Second Artillery Corps of Chinese PLA   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antitumor activity; Immunomodulation; Murine sarcoma 180; Polysaccharide; Portulaca oleracea; Purification

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTITUMOR EFFECT; BIOCHEMICAL ANALYSIS; IMMUNO MODULATIONS; IMMUNOSTIMULATING; MURINE SARCOMA 180; PORTULACA OLERACEA; WHITE BLOOD CELLS;

AMINO ACIDS; POLYSACCHARIDES; PURIFICATION; TUMORS; UREA;

T-CELLS;

ALANINE AMINOTRANSFERASE; ANTINEOPLASTIC AGENT; ASPARTATE AMINOTRANSFERASE; CREATININE; POLYSACCHARIDE;

ANIMAL; ARTICLE; BLOOD; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; PATHOLOGY; PLANT; PORTULACA; SARCOMA 180; UREA NITROGEN BLOOD LEVEL;

ALANINE TRANSAMINASE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ASPARTATE AMINOTRANSFERASES; BLOOD UREA NITROGEN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CREATININE; DRUG SCREENING ASSAYS, ANTITUMOR; MICE; MICE, INBRED ICR; PLANT COMPONENTS, AERIAL; POLYSACCHARIDES; PORTULACA; SARCOMA 180;

ANIMALIA; MURINAE; MUS; PORTULACA OLERACEA;

EID: 84874175659     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2012.11.107     Document Type: Article

References (26)

1. N.E. Awad Lipid content and antimicrobial activity of phenolic constituents of cultivated Portulaca oleracea L. Bulletin of Faculty of Pharmacy 32 1994 137 142
2. T. Bitter, and H.M. Muir A modified uronic acid carbazole reaction Analytical biochemistry 4 1962 330 334
3. A.T. Borchers, J.S. Stern, R.M. Hackman, C.L. Keen, and M.E. Gershwin Mushrooms, tumors, and immunity Proceedings of the Society for Experimental Biology and Medicine 221 1999 281 293
4. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein binding Analytical Biochemistry 72 1976 248 254
5. K. Chan, M.W. Islam, M. Kamil, R. Radhakrishnan, M.N. Zakaria, and M. Habibullah The analgesic and anti-inflammatory effects of Portulaca oleracea L. subsp. Sativa (Haw.) Celak Journal of Ethnopharmacology 73 2000 445 451
6. M.A. Dkhil, A.E. Abdel Moniem, S. Al-Quraishy, and R.A. Saleh Antioxidant effect of purslane (Portulaca oleracea) and its mechanism of action Journal of Medicinal Plants Research 5 2011 1563 1589
7. M. Dubois, K.A. Gilles, J.K. Hamilton, P.A. Rebers, and F. Smith Colorimetric method for determination of sugars and related substances Analytical Chemistry 28 1956 350 356
8. M. Fukushima The overdose of drugs in Japan Nature 342 1989 850 851
9. M. Gerloni, and M. Zanetti CD4 T cells in tumor immunity Springer Seminars in Immunopathology 27 2005 37 48
10. J.W. Hadden Immunodeficiency and cancer: Prospects for correction International Immunopharmacology 3 2003 1061 1071
11. M.Y.K. Leung, C. Liu, J.C.M. Koon, and K.P. Fung Polysaccharide biological response modifiers Immunology Letters 105 2006 101 114
12. F. Liu, V.E.C. Ooi, and M.C. Fung Analysis of immunomodulating cytokine mRNA in the mouse induced by mushroom polysaccharides Life Science 64 1999 1005 1011
13. A. Misaki, M. Kakuta, T. Sakaki, M. Tanaka, and H. Miyaji Studies on interrelation of structure and antitumor effects of polysaccharides: Antitumor action of periodate-modified, branched (1 goes to 3)-beta-d-glucan of Auricularia auriculajudae, and other polysaccharides containing (1 goes to 3)-glycosidic linkages Carbohydrate Research 92 1981 115 129
14. T.B. Mohammad, H.B. Mohammad, and M. Farhad Antitussive effect of Portulaca oleracea L. in guinea pigs Iranian Journal of Pharmaceutical Research 3 2004 187 190
15. H. Mushiake, T. Tsunoda, M. Nukatsuka, K. Shimao, M. Fukushima, and H. Tahara Dendritic cells might be one of key factors for eliciting antitumor effect by chemoimmunotherapy in vivo Cancer Immunology Immunotherapy 54 2005 120 128
16. V.E.C. Ooi, and F. Liu Immunomodulation and anticancer activity of polysaccharide protein complexes Current Medicinal Chemistry 7 2000 715 729
17. M. Poupot, F. Pont, and F. Jean-Jacques Profiling blood lymphocyte interactions with cancer cells uncovers the innate reactivity of human γδT cells to anaplastic large cell lymphoma Journal of Immunology 174 2005 1717 1722
18. A.N. Rashed, F.U. Afifi, and A.M. Disi Simple evaluation of the wound healing activity of a crude extract of Portulaca oleracea L. (growing in Jordan) in Mus musculus JVI-1 Journal of Ethnopharmacology 88 2003 131 136
19. N. Sakai, K. Inada, M. Okamoto, Y. Shizuri, and Y. Fukuyama Portuloside A, a monoterpene glucoside from Portulaca oleracea Phytochemistry 42 1996 1625 1628
20. M.L. Salgaller, and P.A. Lodge Use of cellular and cytokine adjuvants in the immunotherapy of cancer Journal of Surgical Oncology 68 1998 122 138
21. M.G. Sevag, D.B. Lackman, and J. Smolens The isolation of the components of streptococcal nucleoproteins in serologically active form Journal of Biological Chemistry 124 1938 425 436
22. X.H. Shuai, T.J. Hu, H.L. Liu, Z. Su, Y. Zeng, and Y.H. Li Immunomodulatory effect of a Sophora subprosrate polysaccharide in mice International Journal of Biological Macromolecules 46 2010 79 84
23. L. Xiang, D. Xing, W. Wang, R. Wang, Y. Ding, and L. Du Alkaloids from Portulaca oleracea L. Phytochemistry 66 2005 2595 2601
24. J.B. Xiao, J.L. Huo, H.X. Jiang, and F. Yang Chemical compositions and bioactivities of crude polysaccharides from tea leaves beyond their useful date International Journal of Biological Macromolecules 49 2011 1143 1151
25. T.H. Yang, M. Jia, J. Meng, H. Wu, and Q.B. Mei Immunomodulatory activity of polysaccharide isolated from Angelica sinensis International Journal of Biological Macromolecules 39 2006 179 184
26. X.J. Zhang, Y.B. Ji, Z.Y. Qu, J.C. Xia, and L. Wang Experimental studies on antibiotic functions of Portulaca oleracea L. in vitro Chinese Journal of Microbiology 14 2002 277 280