Retraction: HLA-B35 and dsRNA induce endothelin-1 via activation of ATF4 in human microvascular endothelial cells (PLoS ONE (2013) 8:2 (e56123) DOI: 10.1371/journal.pone.0056123);HLA-B35 and dsRNA Induce Endothelin-1 via Activation of ATF4 in Human Microvascular Endothelial Cells

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Lenna, Stefania ^a   Chrobak, Izabela ^a   Farina, G Alessandra ^a   Rodriguez Pascual, Fernando ^b   Lamas, Santiago ^b   Lafyatis, Robert ^a   Scorza, Raffaella ^c   Trojanowska, Maria ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^c FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; DOUBLE STRANDED RNA; ENDOTHELIN 1; GLUCOSE REGULATED PROTEIN 78; HLA B35 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 2ALPHA; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; PREPROENDOTHELIN 1; PROTEIN C JUN; PROTEIN KINASE; PROTEIN KINASE R; RNA DEPENDENT PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; STRESS ACTIVATED PROTEIN KINASE; THAPSIGARGIN; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TRANSCRIPTION INITIATION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

EID: 84874128788     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0241404     Document Type: Erratum

References (33)

1. Kawanabe Y, Nauli SM, (2011) Endothelin. Cell Mol Life Sci 68: 195-203.
2. Shao D, Park JE, Wort SJ, (2011) The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension. Pharmacol Res 63: 504-511.
3. Tsui JC, Shi-Wen X, (2011) Endothelin-1 in peripheral arterial disease: a potential role in muscle damage. Pharmacol Res 63: 473-476.
4. Rodriguez-Pascual F, Busnadiego O, Lagares D, Lamas S, (2011) Role of endothelin in the cardiovascular system. Pharmacol Res 63: 463-472.
5. Stow LR, Jacobs ME, Wingo CS, Cain BD, (2011) Endothelin-1 gene regulation. FASEB J 25: 16-28.
6. Rodriguez-Pascual F, Redondo-Horcajo M, Lamas S, (2003) Functional cooperation between Smad proteins and activator protein-1 regulates transforming growth factor-beta-mediated induction of endothelin-1 expression. Circ Res 92: 1288-1295.
7. Aitsebaomo J, Kingsley-Kallesen ML, Wu Y, Quertermous T, Patterson C, (2001) Vezf1/DB1 is an endothelial cell-specific transcription factor that regulates expression of the endothelin-1 promoter. J Biol Chem 276: 39197-39205.
8. Zhang K, Kaufman RJ, (2008) From endoplasmic-reticulum stress to the inflammatory response. Nature 454: 455-462.
9. Rath E, Haller D, (2011) Inflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologies. Eur J Nutr 50: 219-233.
10. Gargalovic PS, Gharavi NM, Clark MJ, Pagnon J, Yang WP, et al. (2006) The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arterioscler Thromb Vasc Biol 26: 2490-2496.
11. He B, (2006) Viruses, endoplasmic reticulum stress, and interferon responses. Cell Death Differ 13: 393-403.
12. Martinon F, Chen X, Lee AH, Glimcher LH, (2010) TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat Immunol 11: 411-418.
13. Arnett FC, Howard RF, Tan F, Moulds JM, Bias WB, et al. (1996) Increased prevalence of systemic sclerosis in a Native American tribe in Oklahoma. Association with an Amerindian HLA haplotype. Arthritis Rheum 39: 1362-1370.
14. Santaniello A, Salazar G, Lenna S, Antonioli R, Colombo G, et al. (2006) HLA-B35 upregulates the production of endothelin-1 in HLA-transfected cells: a possible pathogenetic role in pulmonary hypertension. Tissue Antigens 68: 239-244.
15. Scorza R, Caronni M, Bazzi S, Nador F, Beretta L, et al. (2002) Post-menopause is the main risk factor for developing isolated pulmonary hypertension in systemic sclerosis. Ann N Y Acad Sci 966: 238-246.
16. Lenna S, Townsend DM, Tan FK, Kapanadze B, Markiewicz M, et al. (2010) HLA-B35 upregulates endothelin-1 and downregulates endothelial nitric oxide synthase via endoplasmic reticulum stress response in endothelial cells. J Immunol 184: 4654-4661.
17. Farina G, York M, Collins C, Lafyatis R, (2011) dsRNA activation of endothelin-1 and markers of vascular activation in endothelial cells and fibroblasts. Ann Rheum Dis 70: 544-550.
18. Lenna S, Townsend DM, Tan FK, Kapanadze B, Markiewicz M,et al. HLA-B35 upregulates endothelin-1 and downregulates endothelial nitric oxide synthase via endoplasmic reticulum stress response in endothelial cells. J Immunol 184: 4654-4661.
19. Pfaller CK, Li Z, George CX, Samuel CE, (2011) Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response. Curr Opin Immunol 23: 573-582.
20. Sulli A, Soldano S, Pizzorni C, Montagna P, Secchi ME, et al. (2009) Raynaud's phenomenon and plasma endothelin: correlations with capillaroscopic patterns in systemic sclerosis. J Rheumatol 36: 1235-1239.
21. Kato Y, Koike Y, Tomizawa K, Ogawa S, Hosaka K, et al. (1999) Presence of activating transcription factor 4 (ATF4) in the porcine anterior pituitary. Mol Cell Endocrinol 154: 151-159.
22. Ameri K, Harris AL, (2008) Activating transcription factor 4. Int J Biochem Cell Biol 40: 14-21.
23. Caselli E, Benedetti S, Grigolato J, Caruso A, Di Luca D, (2012) Activating transcription factor 4 (ATF4) is upregulated by human herpesvirus 8 infection, increases virus replication and promotes proangiogenic properties. Arch Virol 157: 63-74.
24. Malabanan KP, Kanellakis P, Bobik A, Khachigian LM, (2008) Activation transcription factor-4 induced by fibroblast growth factor-2 regulates vascular endothelial growth factor-A transcription in vascular smooth muscle cells and mediates intimal thickening in rat arteries following balloon injury. Circ Res 103: 378-387.
25. Malabanan KP, Khachigian LM, (2010) Activation transcription factor-4 and the acute vascular response to injury. J Mol Med (Berl) 88: 545-552.
26. Kawai T, Akira S, (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384.
27. Yu M, Levine SJ, (2011) Toll-like receptor, RIG-I-like receptors and the NLRP3 inflammasome: key modulators of innate immune responses to double-stranded RNA viruses. Cytokine Growth Factor Rev 22: 63-72.
28. Zimmer S, Steinmetz M, Asdonk T, Motz I, Coch C, et al. (2011) Activation of endothelial toll-like receptor 3 impairs endothelial function. Circ Res 108: 1358-1366.
29. Agarwal SK, Wu M, Livingston CK, Parks DH, Mayes MD, et al. (2011) Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts. Arthritis Res Ther 13: R3.
30. van Bon L, Cossu M, Radstake TR, (2011) An update on an immune system that goes awry in systemic sclerosis. Curr Opin Rheumatol 23: 505-510.
31. Doukas J, Cutler AH, Mordes JP, (1994) Polyinosinic:polycytidylic acid is a potent activator of endothelial cells. Am J Pathol 145: 137-147.
32. Shibamiya A, Hersemeyer K, Schmidt Woll T, Sedding D, Daniel JM, et al. (2009) A key role for Toll-like receptor-3 in disrupting the hemostasis balance on endothelial cells. Blood 113: 714-722.
33. Chan SY, Loscalzo J, (2008) Pathogenic mechanisms of pulmonary arterial hypertension. J Mol Cell Cardiol 44: 14-30.