Profiling two indole-2-carboxamides for allosteric modulation of the CB1 receptor

Journal of Neurochemistry

Volumn 124, Issue 5, 2013, Pages 584-589

  Ahn, Kwang H ^a   Mahmoud, Mariam M ^a   Samala, Sushma ^b   Lu, Dai ^b   Kendall, Debra A ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

allosteric modulator; biased signaling; CB1; G protein coupling; GPCR; ligand binding

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 5 CHLORO 3 ETHYL 1 METHYL N [4 (PIPERIDIN 1 YL)PHENETHYL] 1H INDOLE 2 CARBOXAMIDE; 5 CHLORO 3 PENTYL N [4 (PIPERIDIN 1 YL)PHENETHYL] 1H INDOLE 2 CARBOXAMIDE; AMIDE; BETA ARRESTIN; CANNABINOID 1 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; INDOLES; LIGANDS; PIPERIDINES; PROTEIN BINDING; RECEPTOR, CANNABINOID, CB1; SIGNAL TRANSDUCTION;

EID: 84874117655     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12115     Document Type: Article

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