Production of sophorolipids with enhanced volumetric productivity by means of high cell density fermentation

Applied Microbiology and Biotechnology

Volumn 97, Issue 3, 2013, Pages 1103-1111

  Gao, Renjun ^a,b   Falkeborg, Mia ^a   Xu, Xuebing ^a   Guo, Zheng ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b JILIN UNIVERSITY   (China)

Author keywords

Biosurfactants; Candida bombicola; High cell density fermentation; Sophorolipids; Volumetric productivity

Indexed keywords

BIO-SURFACTANTS; CANDIDA BOMBICOLA; HIGH CELL DENSITY FERMENTATIONS; SOPHOROLIPIDS; VOLUMETRIC PRODUCTIVITY;

CANDIDA; CELLS; CYTOLOGY; FERMENTATION; YEAST;

PRODUCTIVITY;

BIOSURFACTANT; SOPHOROLIPID; SOPHOROSE; UNCLASSIFIED DRUG;

BIOLOGICAL PRODUCTION; BIOMASS; CARBON; CELL ORGANELLE; COMPUTER SIMULATION; CONCENTRATION (COMPOSITION); FERMENTATION; LIPID; NUTRIENT CYCLING; SURFACTANT; VOLUME; YEAST;

ARTICLE; BIOMASS FERMENTATION; BIOMASS PRODUCTION; BIOREACTOR; CANDIDA; CANDIDA BOMBICOLA; CARBON SOURCE; CELL DENSITY; CONTROLLED STUDY; DRY WEIGHT; FERMENTATION OPTIMIZATION; FUNGAL BIOMASS; FUNGAL CELL; HIGH CELL DENSITY FERMENTATION; NONHUMAN; NUTRIENT CONCENTRATION; PHYSICAL PARAMETERS; PRODUCTIVITY;

BIOMASS; BIOTECHNOLOGY; CANDIDA; CELL COUNT; CULTURE MEDIA; FERMENTATION; LIPID METABOLISM; TIME FACTORS;

STARMERELLA BOMBICOLA;

EID: 84874113629     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4399-z     Document Type: Article

References (34)

1. Ashby RD, Solaiman DKY, Foglia TA (2006) The use of fatty acid esters to enhance free acid sophorolipid synthesis. Biotechnol Lett 28:253-260
2. Bahcegul E, Tatli E, Haykir NI, Apaydin S, Bakir U (2011) Selecting the right blood glucose monitor for the determination of glucose during the enzymatic hydrolysis of corncob pretreated with different methods. Bioresour Technol 102:9646-9652
3. Banik RM, Santhiagu A, Kanari B, Sabarinath C, Upadhyay SN (2003) Technological aspects of extractive fermentation using aqueous two-phase systems. World J Microbiol Biotechnol 19(4):337-348
4. Casas JA, Garcia-Ochoa F (1999) Sophorolipid production by Candida bombicola: medium composition and culture methods. J Biosci Bioeng 88(5):488-494
5. Cavalero DA, Cooper DG (2003) The effect of medium composition on the structure and physical state of sophorolipids produced by Candida bombicola ATCC 22214. J Biotechnol 103:31-41
6. Daniel H-J, Otto RT, Reuss M, Syldatk C (1998a) Production of sophorolipids in high concentration from deproteinized whey and rapeseed oil in a two stage fed batch process using Candida bombicola ATCC 22214 and Cryptococcus curvatus ATCC 20509. Biotechnol Lett 20(12):1153-1156
7. Daniel H-J, Otto RT, Reuss M, Syldatk C (1998b) Sophorolipid production with high yields on whey concentrate and rapeseed oil without consumption of lactose. Biotechnol Lett 20(8):805-807
8. Daverey A, Pakshirajan K (2009) Production of sophorolipids by the yeast Candida bombicola using simple and low cost fermentative media. Food Res Int 42:499-504
9. Daverey A, Pakshirajan K, Sangeetha P (2009) Sophorolipids production by Candida bombicola using synthetic dairy wastewater. Int J Civ Environ Eng 1(4):174-176
10. Davila AM, Marchel R, Vandecasteele JP (1992) Kinetics and balance of a fermentation free from product inhibition: sophorose lipid production by Candida bombicola. Appl Microbiol Biotechnol 38:6-11
11. Davila AM, Marchal R, Monin N, Vandecasteele JP (1993) Identification and determination of individual sophorolipids in fermentation products by gradient elution high-performance liquid chromatography with evaporative light-scattering detection. J Chromatogr 648:139-149
12. Davila AM, Marchel R, Vandecasteele JP (1997) Sophorose lipid fermentation with differentiated substrate supply for growth and production phases. Appl Microbiol Biotechnol 47:496-501
13. Deshpande M, Daniels L (1995) Evaluation of sophorolipid biosurfactant production by Candida bombicola using animal fat. Bioresour Technol 54:143-150
14. Felse PA, Shah V, Chan J, Rao KJ, Gross RA (2007) Sophorolipid biosynthesis by Candida bombicola from industrial fatty acid residues. Enzyme Microb Technol 40:316-323
15. Fu SL, Wallner SR, Bowne WB, Hagler MD, Zenilman ME, Gross R, Bluth MH (2008) Sophorolipids and their derivatives are lethal against human pancreatic cancer cells. J Surg Res 148:77-82
16. Guilmanov V, Ballistreri A, Impallomeni G (2002) Oxygen transfer rate and sophorose lipid production by Candida bombicola. Biotechnol Bioeng 77(5):489-494
17. Hardin R, Pierre J, Schulze R, Mueller CM, Fu SL, Wallner SR, Stanek A, Shah V, Gross RA, Weedon J, Nowakowski M, Zenilman ME, Bluth MH (2007) Sophorolipids improve sepsis survival: effects of dosing and derivatives. J Surg Res 142(2):314-319
18. Herbert D, Phipps PJ, Strange RE (1971) Chemical analysis of microbial cells. Method Microbiol 5 Part B:209-344
19. Kim SY, Oh DK, Lee KH, Kim JH (1997) Effect of soybean oil and glucose on sophorose lipid fermentation by Torulopsis bombicola in continuous culture. Appl Microbiol Biotechnol 48:23-26
20. Kim Y-B, Yun HS, Kim E-K (2009) Enhanced sophorolipid production by feeding-rate-controlled fed-batch culture. Bioresour Technol 100:6028-6032
21. Kleman GL, Strohl WR (1992) High cell density and high-productivity microbial fermentation. Curr Opin Biotechnol 3:93-98
22. Kleman GL, Strohl WR (1994) Developments in high cell density and high productivity microbial fermentation. Curr Opin Biotechnol 5:180-186
23. Mukherjee S, Das P, Sen R (2006) Towards commercial production of microbial surfactants. Trends Biotechnol 24(11):509-515
24. Muthusamy K, Gopalakrishnan S, Ravi TK, Sivachidambaram P (2008) Biosurfactants: properties, commercial production and application. Curr Sci India 94(6):736-747
25. Pekin G, Vardar-Sukan F, Kosaric N (2005) Production of sophorolipids from Candida bombicola ATCC 22214 using Turkish corn oil and honey. Eng Life Sci 5(4):357-362
26. Rau U, Manzke C, Wagner F (1996) Influence of substrate supply on the production of sophorose lipids by Candida bombicola ATCC 22214. Biotechnol Lett 18:149-154
27. Rau U, Hammen S, Heckmann R, Wray V, Lang S (2001) Sophorolipids: a source for novel compounds. Ind Crop Prod 13:85-92
28. Saerens KMJ, Saey L, Soetaert W (2011) One-step production of unacetylated sophorolipids by an acetyltransferase negative Candida bombicola. Biotechnol Bioeng 108:2923-2931
29. Shah V, Jurjevic M, Badia D (2007) Utilization of restaurant waste oil as a precursor for sophorolipid production. Biotechnol Prog 23:512-515
30. Singh SK, Felse AP, Nunez A, Foglia TA, Gross RA (2003) Regioselective enzyme-catalyzed synthesis of sophorolipid esters, amides, and multifunctional monomers. J Org Chem 68:5466-5477
31. Solaiman DKY, Ashby RD, Zerkowski JA, Foglia TA (2007) Simplified soy molasses-based medium for reduced-cost production of sophorolipids by Candida bombicola. Biotechnol Lett 29:1341-1347
32. Spencer JFT, Spencer DM, Tulloch AP (1979) Extracellular glycolipids of yeasts. Econ Microbiol 3:523-540
33. Van Bogaert INA, Saerens K, De Muynck C, Develter D, Soetaert W, Vandamme EJ (2007) Microbial production and application of sophorolipids. Appl Microbiol Biotechnol 76:23-34
34. Zhou Q-H, Klekner V, Kosaric N (1992) Production of sophorose lipids by Torulopsis bombicola from safflower oil and glucose. J Am Oil Chem Soc 69:89-91