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Volumn 48, Issue 1, 2013, Pages 184-189

Preparative method for isosilybin isolation based on enzymatic kinetic resolution of silymarin mixture

Author keywords

Diastereomers; Isosilybin; Novozym 435; Silybin; Silymarin

Indexed keywords

DIASTEREOMERS; ISOSILYBIN; NOVOZYM435; SILYBIN; SILYMARIN;

EID: 84874112594     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2012.11.006     Document Type: Article
Times cited : (19)

References (16)
  • 1
    • 33847265733 scopus 로고    scopus 로고
    • Silybin and silymarin-new and emerging applications in medicine
    • R. Gažák, D. Walterová, and V. Křen Silybin and silymarin-new and emerging applications in medicine Curr Med Chem 14 2007 315 338
    • (2007) Curr Med Chem , vol.14 , pp. 315-338
    • Gažák, R.1    Walterová, D.2    Křen, V.3
  • 2
    • 0028956461 scopus 로고
    • Silybum marianum (Carduus marianus)
    • P. Morazzoni, and E. Bombardelli Silybum marianum (Carduus marianus) Fitoterapia 66 1995 3 42
    • (1995) Fitoterapia , vol.66 , pp. 3-42
    • Morazzoni, P.1    Bombardelli, E.2
  • 3
    • 29344461962 scopus 로고    scopus 로고
    • Effect of silymarin and its polyphenolic fraction on cholesterol absorption in rats
    • L. Sobolová, N. Škottová, R. Večeřa, and K. Urbánek Effect of silymarin and its polyphenolic fraction on cholesterol absorption in rats Pharmacol Res 53 2006 104 112
    • (2006) Pharmacol Res , vol.53 , pp. 104-112
    • Sobolová, L.1    Škottová, N.2    Večeřa, R.3    Urbánek, K.4
  • 4
    • 57349142011 scopus 로고    scopus 로고
    • Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: Comparison with silymarin and silibinin
    • G. Deep, K. Raina, R.P. Singh, N.H. Oberlies, D.J. Kroll, and R. Agarwal Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin Int J Cancer 123 2008 2750 2758
    • (2008) Int J Cancer , vol.123 , pp. 2750-2758
    • Deep, G.1    Raina, K.2    Singh, R.P.3    Oberlies, N.H.4    Kroll, D.J.5    Agarwal, R.6
  • 5
    • 0017371328 scopus 로고
    • Callus- und Suspensionskulturen von Silybum marianum
    • R. Schrall, and H. Becker Callus- und Suspensionskulturen von Silybum marianum Planta Med 32 1977 27 32
    • (1977) Planta Med , vol.32 , pp. 27-32
    • Schrall, R.1    Becker, H.2
  • 6
    • 0141566436 scopus 로고    scopus 로고
    • Molecular structure and stereochemistry of silybin A, silybin B, isosilybin A, and isosilybin B, isolated from Silybum marianum (milk thistle)
    • D.Y-W. Lee, and Y. Liu Molecular structure and stereochemistry of silybin A, silybin B, isosilybin A, and isosilybin B, isolated from Silybum marianum (milk thistle) J Nat Prod 66 2003 1171 1174
    • (2003) J Nat Prod , vol.66 , pp. 1171-1174
    • Lee, D.Y.-W.1    Liu, Y.2
  • 7
    • 0141974905 scopus 로고    scopus 로고
    • Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum)
    • N-C. Kim, T.N. Graf, C.M. Sparacino, M.C. Wani, and M.E. Wall Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum) Org Biomol Chem 1 2003 1684 1689
    • (2003) Org Biomol Chem , vol.1 , pp. 1684-1689
    • Kim, N.-C.1    Graf, T.N.2    Sparacino, C.M.3    Wani, M.C.4    Wall, M.E.5
  • 8
    • 36949024949 scopus 로고    scopus 로고
    • Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention
    • T.N. Graf, M.C. Wani, R. Agarwal, D.J. Kroll, and N.H. Oberlies Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention Planta Med 73 2007 1495 1501
    • (2007) Planta Med , vol.73 , pp. 1495-1501
    • Graf, T.N.1    Wani, M.C.2    Agarwal, R.3    Kroll, D.J.4    Oberlies, N.H.5
  • 9
    • 77951064218 scopus 로고    scopus 로고
    • Large-scale isolation of flavonolignans from Silybum marianum extract affords new minor constituents and preliminary structure-activity relationships
    • A. Sy-Cordero, T.N. Graf, Y. Nakanishi, M.C. Wani, R. Agarwal, and D.J. Kroll Large-scale isolation of flavonolignans from Silybum marianum extract affords new minor constituents and preliminary structure-activity relationships Planta Med 76 2010 644 647
    • (2010) Planta Med , vol.76 , pp. 644-647
    • Sy-Cordero, A.1    Graf, T.N.2    Nakanishi, Y.3    Wani, M.C.4    Agarwal, R.5    Kroll, D.J.6
  • 10
    • 77950299488 scopus 로고    scopus 로고
    • Isolation and purification of silychristin, silydianin and taxifolin in the co-products of the silybin refined process from the silymarin by high-speed counter-current chromatography
    • H. Liu, Q. Yuan, C.F. Li, and T.X. Huang Isolation and purification of silychristin, silydianin and taxifolin in the co-products of the silybin refined process from the silymarin by high-speed counter-current chromatography Process Biochem 45 2010 799 804
    • (2010) Process Biochem , vol.45 , pp. 799-804
    • Liu, H.1    Yuan, Q.2    Li, C.F.3    Huang, T.X.4
  • 11
    • 34547796445 scopus 로고    scopus 로고
    • Isosilybin B and isosilybin A inhibit growth, induce G(1) arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells
    • G. Deep, N.H. Oberlies, D.J. Kroll, and R. Agarwal Isosilybin B and isosilybin A inhibit growth, induce G(1) arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells Carcinogenesis 7 2007 1533 1542
    • (2007) Carcinogenesis , vol.7 , pp. 1533-1542
    • Deep, G.1    Oberlies, N.H.2    Kroll, D.J.3    Agarwal, R.4
  • 12
    • 20144372639 scopus 로고    scopus 로고
    • Milk thistle and prostate cancer: Differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells
    • P.R. Davis-Searles, Y. Nakanishi, T.N. Kim N-Ch Graf, N.H. Oberlies, M.C. Wani, and M.E. Wall Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells Cancer Res 65 2005 4448 4457
    • (2005) Cancer Res , vol.65 , pp. 4448-4457
    • Davis-Searles, P.R.1    Nakanishi, Y.2    Kim N-Ch Graf, T.N.3    Oberlies, N.H.4    Wani, M.C.5    Wall, M.E.6
  • 16
    • 80052079350 scopus 로고    scopus 로고
    • Narrow-bore core-shell particles and monolithic columns in the analysis of silybin diastereoisomers
    • P. Marhol, R. Gažák, P. Bednář, and V. Křen Narrow-bore core-shell particles and monolithic columns in the analysis of silybin diastereoisomers J Sep Sci 34 2011 2206 2213
    • (2011) J Sep Sci , vol.34 , pp. 2206-2213
    • Marhol, P.1    Gažák, R.2    Bednář, P.3    Křen, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.