Large-scale isolation of flavonolignans from silybum marianum extract affords new minor constituents and preliminary structure-activity relationships

Planta Medica

Volumn 76, Issue 6, 2010, Pages 644-647

  Sy Cordero, Arlene ^a   Graf, Tyler N ^a   Nakanishi, Yuka ^a   Wani, Mansukh C ^a   Agarwal, Rajesh ^b   Kroll, David J ^c   Oberlies, Nicholas H ^a  

^a RTI INTERNATIONAL   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

Author keywords

Asteraceae; Isosilybin; Milk thistle; Silybin; Silybum marianum; Silymarin

Indexed keywords

ANTINEOPLASTIC AGENT; FLAVONOLIGNAN; ISOSILYBIN A; ISOSILYBIN B; ISOSILYBIN C; ISOSILYBIN D; SILYBIN A; SILYBIN B; SILYBUM MARIANUM EXTRACT; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DIASTEREOISOMER; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; PROSTATE CANCER; SILYBUM MARIANUM; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; FLAVONOLIGNANS; HUMANS; MALE; MILK THISTLE; MOLECULAR STRUCTURE; PLANT EXTRACTS; PROSTATIC NEOPLASMS; SILYMARIN; STRUCTURE-ACTIVITY RELATIONSHIP;

ASTERACEAE; SILYBUM MARIANUM;

EID: 77951064218     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1240624     Document Type: Article

References (11)

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