Chronic non-cancer-related pain: Long-term treatment with rapid-release and short-acting opioids in the context of misuse and dependency;Chronische nichttumorbedingte Schmerzen: Langzeitbehandlung mit schnell freisetzenden und kurz wirksamen Opioiden im Kontext von Missbrauch und Abhängigkeit

Schmerz

Volumn 27, Issue 1, 2013, Pages 7-19

  Scharnagel, R ^a   Kaiser, U ^a   Schutze A ^a   Heineck, R ^a   Gossrau, G ^a   Sabatowski, R ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

Fentanyl; Opioid dependency; Oxycodone; Prescription drug misuse; Tilidine

Indexed keywords

OPIATE;

ARTICLE; CHRONIC PAIN; DRUG EFFICACY; DRUG MISUSE; DRUG RELEASE; HUMAN; LONG TERM CARE; OPIATE ADDICTION; PRACTICE GUIDELINE;

ABDOMINAL PAIN; ADULT; ANALGESICS, OPIOID; CHRONIC PAIN; DIABETIC NEUROPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG UTILIZATION; FEMALE; FENTANYL; GUIDELINE ADHERENCE; HEADACHE DISORDERS; HUMANS; LONG-TERM CARE; MALE; MIDDLE AGED; OPIOID-RELATED DISORDERS; OXYCODONE; PHYSICIAN'S PRACTICE PATTERNS; PHYSICIAN-PATIENT RELATIONS; PRESCRIPTION DRUG MISUSE; RISK FACTORS; TILIDINE;

EID: 84874111239     PISSN: 0932433X     EISSN: 14322129     Source Type: Journal    
DOI: 10.1007/s00482-012-1278-6     Document Type: Article

References (79)

1. Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) (2012) Langzeitanwendung von Opioiden bei nicht-tumorbedingten Schmerzen (LONTS). http://www.awmf.org/uploads/tx- szleitlinien/041-003l.pdf. Zugegriffen: 6. Juli 2012
2. Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) (2010) Medikamentenabhängigkeit (Sedativa-Hypnotika, Analgetika, Psychostimulantien). http://www.awmf.org/ uploads/tx-szleitlinien/076-009-S2-Medikamentenabhaengigkeit-05-2006-05-2011. pdf. Zugegriffen: 18. Oktober 2010
3. Arzneimittelkommission der deutschen Ärzteschaft (2012) Abhängigkeitspotenzial von Pregabalin (Lyrica®) (Aus der UAW-Datenbank). http://www.akdae.de/Arzneimittelsicherheit/Bekanntgaben/Archiv/ 2011/20110128.html. Zugegriffen: 5. September 2012
4. Ashburn MA, Slevin KA, Messina J, Xie F (2011) The efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain. Anesth Analg 112:693-702
5. Ballantyne JC, LaForge KS (2007) Opioid dependence and addiction during opioid treatment of chronic pain. Pain 129:235-255
6. Bell J (2010) The global diversion of pharmaceutical drugs: opiate treatment and the diversion of pharmaceutical opiates: a clinician's perspective. Addiction 105:1531-1537
7. Bohnert AS, Valenstein M, Bair MJ, et al. (2011) Association between opioid prescribing patterns and opioid overdose-related deaths. JAMA 305:1315-1321
8. Bradshaw DH, Empy C, Davis P, Lipschitz D, et al. (2008) Trends in funding for research on pain: a report on the National Institutes Of Health grant awards over the years 2003-2007. J Pain 9:1077-1087
9. Bundesinstitut für Arzneimittel und Medizinprodukte (2012) Sachverständigenausschuss für Betäubungsmittel. http://www.bfarm.de/DE/Bundesopiumstelle/BtM/sachverst/Protokolle/Ergebnisse-38. html. Zugegriffen: 22. August 2012
10. Caraceni A, Hanks G, Kaasa S, et al. (2012) Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC. Lancet Oncol 13:e58-e68
11. Caraceni A, Pigni A, Brunelli C (2011) Is oral morphine still the first choice opioid for moderate to severe cancer pain? A systematic review within the European Palliative Care Research Collaborative guidelines project. Palliat Med 25:402-409
12. Chapman CR, Lipschitz DL, Angst MS, et al. (2010) Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base. J Pain 11:807-829
13. Chou R (2010) What we still don't know about treating chronic noncancer pain with opioids. CMAJ 182:881-882
14. Chou R, Ballantyne JC, Fanciullo GJ, et al. (2009) Research gaps on use of opioids for chronic noncancer pain: findings from a review of the evidence for an American Pain Society and American Academy of Pain Medicine clinical practice guideline. J Pain 10:147-159
15. Chou R, Clark E, Helfand M (2003) Comparative efficacy and safety of long-acting oral opioids for chronic non-cancer pain: a systematic review. J Pain Symptom Manage 26:1026-1048
16. Chou R, Fanciullo GJ, Fine PG, et al. (2009) Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. J Pain 10:113-130
17. Chou R, Fanciullo GJ, Fine PG, et al. (2009) Opioids for chronic noncancer pain: prediction and identification of aberrant drug-related behaviors: a review of the evidence for an American Pain Society and American Academy of Pain Medicine clinical practice guideline. J Pain 10:131-146
18. Cicero TJ, Lynskey M, Todorov A, et al. (2008) Co-morbid pain and psychopathology in males and females admitted to treatment for opioid analgesic abuse. Pain 139:127-135
19. Compton WM, Volkow ND (2006) Major increases in opioid analgesic abuse in the United States: concerns and strategies. Drug Alcohol Depend 81:103-107
20. Davies AN, Dickman A, Reid C, et al. (2009) The management of cancer-related breakthrough pain: recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. Eur J Pain 13:331-338
21. Deutsche Hauptstelle für Suchtfragen e. V. (Hrsg) (2012) Jahrbuch Sucht 2012. Pabst Science, Lengerich
22. Dhalla IA, Mamdani MM, Sivilotti ML, et al. (2009) Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone. CMAJ 181:891-896
23. Dhalla IA, Persaud N, Juurlink DN (2011) Facing up to the prescription opioid crisis. BMJ 343:d5142. DOI: 10.1136/bmj.d5142.:d5142
24. Dilling H, Freyberger HJ (Hrsg) (2008) Taschenführer zur ICD-10-Klassifikation psychischer Störungen. Huber, Bern
25. DIMDI (Hrsg) (2012) ICD-10-GM 2012 Systematisches Verzeichnis. Deutscher Ärzte-Verlag, Köln
26. Dunn KM, Saunders KW, Rutter CM, et al. (2010) Opioid prescriptions for chronic pain and overdose: a cohort study. Ann Intern Med 152:85-92
27. Edlund MJ, Sullivan M, Steffick D, et al. (2007) Do users of regularly prescribed opioids have higher rates of substance use problems than nonusers? Pain Med 8:647-656
28. Farrar JT, Messina J, Xie F, Portenoy RK (2010) A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain. Pain Med 11:1313-1327
29. Fine PG, Mahajan G, McPherson ML (2009) Long-acting opioids and short-acting opioids: appropriate use in chronic pain management. Pain Med 10(Suppl 2):S79-88
30. Fine PG, Messina J, Xie F, et al. (2010) Long-term safety and tolerability of fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic pain: an 18-month study. J Pain Symptom Manage 40:747-760
31. Fine PG, Narayana A, Passik SD (2010) Treatment of breakthrough pain with fentanyl buccal tablet in opioid-tolerant patients with chronic pain: appropriate patient selection and management. Pain Med 11:1024-1036
32. Fishbain DA, Cole B, Lewis J, et al. (2008) What percentage of chronic nonmalignant pain patients exposed to chronic opioid analgesic therapy develop abuse/addiction and/or aberrant drug-related behaviors? A structured evidence-based review. Pain Med 9:444-459
33. Fleming MF, Balousek SL, Klessig CL, et al. (2007) Substance use disorders in a primary care sample receiving daily opioid therapy. J Pain 8:573-582
34. Furlan AD, Reardon R, Weppler C (2010) Opioids for chronic noncancer pain: a new Canadian practice guideline. CMAJ 182:923-930
35. Gilson AM, Kreis PG (2009) The burden of the nonmedical use of prescription opioid analgesics. Pain Med 10(Suppl 2):S89-100
36. Gomes T, Juurlink DN, Dhalla IA, et al. (2011) Trends in opioid use and dosing among socio-economically disadvantaged patients. Open Med 5:e13-e22
37. Hamunen K, Paakkari P, Kalso E (2009) Trends in opioid consumption in the Nordic countries 2002-2006. Eur J Pain 13:954-962
38. Hyman SE, Malenka RC, Nestler EJ (2006) Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci 29:565-598
39. Ives TJ, Chelminski PR, Hammett-Stabler CA, et al. (2006) Predictors of opioid misuse in patients with chronic pain: a prospective cohort study. BMC Health Serv Res 6:46
40. Jage J (2005) Opioid tolerance and dependence - do they matter? Eur J Pain 9:157-162
41. Koob GF, Ahmed SH, Boutrel B, et al. (2004) Neurobiological mechanisms in the transition from drug use to drug dependence. Neurosci Biobehav Rev 27:739-749
42. Landesapothekenkammer Baden-Würtemberg (2012) http://www.lak-bw.de/ infocenter/apothekenpraxis/vorsicht-gefaelschte-rezepte.html. Zugegriffen: 17. Oktober 2012
43. Maier C (2008) Auch Sucht ist eine Krankheit. Schmerz 22:639-643
44. Manchikanti L, Fellows B, Ailinani H, et al. (2010) Therapeutic use, abuse, and nonmedical use of opioids: a ten-year perspective. Pain Physician 13:401-435
45. Manchikanti L, Manchukonda R, Damron KS, et al. (2006) Does adherence monitoring reduce controlled substance abuse in chronic pain patients? Pain Physician 9:57-60
46. Markman JD (2008) Not so fast: the reformulation of fentanyl and breakthrough chronic non-cancer pain. Pain 136:227-229
47. Martell BA, O'Connor PG, Kerns RD, et al. (2007) Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Ann Intern Med 146:116-127
48. McLellan AT, Turner BJ (2010) Chronic noncancer pain management and opioid overdose: time to change prescribing practices. Ann Intern Med 152:123-124
49. Bundesärztekammer in Zusammenarbeit mit der Arzneimittelkommission der deutschen Ärzteschaft (Hrsg) (o J) Medikamente - schädlicher Gebrauch und Abhängigkeit. Leitfaden für die ärztliche Praxis. http://www.bundesaerztekammer.de/downloads/LeitfadenMedAbhaengigkeit.pdf. Zugegriffen: 6. Juli 2012
50. Mercadante S, Radbruch L, Caraceni A, et al. (2002) Episodic (breakthrough) pain: consensus conference of an expert working group of the European Association for Palliative Care. Cancer 94:832-839
51. Michna E, Ross EL, Hynes WL, et al. (2004) Predicting aberrant drug behavior in patients treated for chronic pain: importance of abuse history. J Pain Symptom Manage 28:250-258
52. Noble M, Treadwell JR, Tregear SJ, et al. (2010) Long-term opioid management for chronic noncancer pain. Cochrane Database Syst Rev:CD006605
53. Okie S (2010) A flood of opioids, a rising tide of deaths. N Engl J Med 363:1981-1985
54. Pabst A, Piontek D, Kraus L, Müller S (2010) Substanzkonsum und substanzbezogene Störungen. Ergebnisse des Epidemiologischen Suchtsurveys 2009. Sucht 56:327-336
55. Passik SD (2009) Issues in long-term opioid therapy: unmet needs, risks, and solutions. Mayo Clin Proc 84:593-601
56. Passik SD, Hays L, Eisner N, et al. (2006) Psychiatric and pain characteristics of prescription drug abusers entering drug rehabilitation. J Pain Palliat Care Pharmacother 20:5-13
57. Passik SD, Messina J, Golsorkhi A, et al. (2011) Aberrant drug-related behavior observed during clinical studies involving patients taking chronic opioid therapy for persistent pain and fentanyl buccal tablet for breakthrough pain. J Pain Symptom Manage 41:116-125
58. Porada S (2011) REMS; red tape, or a remedy for opioid abuse? J Fam Pract 60:S55-S62
59. Portenoy RK, Bennett DS, Rauck R, et al. (2006) Prevalence and characteristics of breakthrough pain in opioid-treated patients with chronic noncancer pain. J Pain 7:583-591
60. Portenoy RK, Messina J, Xie F, et al. (2007) Fentanyl buccal tablet (FBT) for relief of breakthrough pain in opioid-treated patients with chronic low back pain: a randomized, placebo-controlled study. Curr Med Res Opin 23:223-233
61. Reinecke H, Sorgatz H (2009) S3-Leitlinie LONTS. Langzeitanwendung von Opioiden bei nicht tumorbedingten Schmerzen. Schmerz 23:440-447
62. Roset PN, Farre M, de la Torre R, et al. (2001) Modulation of rate of onset and intensity of drug effects reduces abuse potential in healthy males. Drug Alcohol Depend 64:285-298
63. Sabatowski R (2012) Critical issues in cancer pain management. Pain Manage 2:201-204
64. Samaha AN, Robinson TE (2005) Why does the rapid delivery of drugs to the brain promote addiction? Trends Pharmacol Sci 26:82-87
65. Savage SR, Joranson DE, Covington EC, et al. (2003) Definitions related to the medical use of opioids: evolution towards universal agreement. J Pain Symptom Manage 26:655-667
66. Schubert I, Ihle P, Sabatowski R (2012) Zunahme der Opioidverordnungen in Deutschland zwischen 2000 und 2010. Eine Studie auf Basis von Krankenkassendaten. Dtsch Arztebl Int (im Druck)
67. Schwabe U, Paffrath D (Hrsg) (2011) Arzneiverordnungsreport 2011. Springer, Berlin
68. Simpson DM, Messina J, Xie F, et al. (2007) Fentanyl buccal tablet for the relief of breakthrough pain in opioid-tolerant adult patients with chronic neuropathic pain: a multicenter, randomized, double-blind, placebo-controlled study. Clin Ther 29:588- 601
69. Soyka M, Queri S, Kufner H, et al. (2005) Wo verstecken sich 1,9 Millionen Medikamentenabhängige? Nervenarzt 76:72-77
70. Sullivan MD, Ballantyne JC (2012) What are we treating with long-term opioid therapy? Arch Intern Med 172:433-434
71. Sullivan MD, Edlund MJ, Zhang L, et al. (2006) Association between mental health disorders, problem drug use, and regular prescription opioid use. Arch Intern Med 166:2087-2093
72. Taylor DR, Webster LR, Chun SY, et al. (2007) Impact of breakthrough pain on quality of life in patients with chronic, noncancer pain: patient perceptions and effect of treatment with oral transmucosal fentanyl citrate (OTFC, ACTIQ). Pain Med 8:281- 288
73. Treede RD, Jensen TS, Campbell JN, et al. (2008) Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology 70:1630-1635
74. Volkow ND, McLellan TA (2011) Curtailing diversion and abuse of opioid analgesics without jeopardizing pain treatment. JAMA 305:1346-1347
75. Volkow ND, McLellan TA, Cotto JH, et al. (2011) Characteristics of opioid prescriptions in 2009. JAMA 305:1299-1301
76. Webster LR, Messina J, Xie F, et al. (2011) Effect of fentanyl buccal tablet on pain-related anxiety: a 4-week open-label study among opioid-tolerant patients with chronic and breakthrough pain. J Opioid Manag 7:297-308
77. Weisner CM, Campbell CI, Ray GT, et al. (2009) Trends in prescribed opioid therapy for non-cancer pain for individuals with prior substance use disorders. Pain 145:287-293
78. Wissenschaftliches Institut der AOK (2012) http:// www.wido.de/fileadmin/ wido/downloads/pdf- arzneimittel/wido-arz-avr2012pk-0912.pdf. Zugegriffen: 17. Oktober 2012
79. Zeppetella G (2011) Opioids for the management of breakthrough cancer pain in adults: a systematic review undertaken as part of an EPCRC opioid guidelines project. Palliat Med 25:516-524