Aberrant drug-related behavior observed during clinical studies involving patients taking chronic opioid therapy for persistent pain and fentanyl buccal tablet for breakthrough pain

Journal of Pain and Symptom Management

Volumn 41, Issue 1, 2011, Pages 116-125

  Passik, Steven D ^a   Messina, John ^b   Golsorkhi, Anthony ^b   Xie, Fang ^b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b CEPHALON INC   (United States)

Author keywords

aberrant drug related behavior; breakthrough pain (BTP); Chronic pain; drug abuse; fentanyl buccal tablet (FBT); opioid

Indexed keywords

FENTANYL; DELAYED RELEASE FORMULATION; NARCOTIC ANALGESIC AGENT; TABLET;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BEHAVIOR; CHRONIC PAIN; DRUG ABUSE; DRUG MISUSE; DRUG OVERDOSE; DRUG TOLERANCE; FEMALE; FOLLOW UP; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; PRESCRIPTION; RETROSPECTIVE STUDY; SEX DIFFERENCE; TABLET; URINALYSIS; WITHDRAWAL SYNDROME; ADOLESCENT; BREAKTHROUGH PAIN; CLINICAL TRIAL (TOPIC); COMORBIDITY; DELAYED RELEASE FORMULATION; EPIDEMIOLOGY; INCIDENCE; INTERNATIONAL COOPERATION; MIDDLE AGED; OPIOID-RELATED DISORDERS; ORAL DRUG ADMINISTRATION; RISK FACTOR; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME; YOUNG ADULT;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; ANALGESICS, OPIOID; BREAKTHROUGH PAIN; CAUSALITY; CHRONIC PAIN; CLINICAL TRIALS AS TOPIC; COMORBIDITY; DELAYED-ACTION PREPARATIONS; FEMALE; FENTANYL; HUMANS; INCIDENCE; INTERNATIONALITY; MALE; MIDDLE AGED; OPIOID-RELATED DISORDERS; RETROSPECTIVE STUDIES; RISK FACTORS; TABLETS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 78651267244     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2010.03.012     Document Type: Article

References (21)

1. J.C. Ballantyne Chronic pain following treatment for cancer: the role of opioids Oncologist 8 2003 567 575
2. A.M. Trescot, M.V. Boswell, and S.L. Atluri Opioid guidelines in the management of chronic non-cancer pain Pain Physician 9 2006 1 39
3. World Health Organization Cancer pain relief and palliative care 1990 World Health Organization Geneva, Switzerland
4. C. Chabal, M.K. Erjavec, L. Jacobson, A. Mariano, and E. Chaney Prescription opiate abuse in chronic pain patients: clinical criteria, incidence, and predictors Clin J Pain 13 1997 150 155
5. E. Michna, E.L. Ross, and W.L. Hynes Predicting aberrant drug behavior in patients treated for chronic pain: importance of abuse history J Pain Symptom Manage 28 2004 250 258
6. S.D. Passik, K.L. Kirsh, L. Whitcomb, P.K. Dickerson, and D.E. Theobald Pain clinicians' rankings of aberrant drug-taking behaviors J Pain Palliat Care Pharmacother 16 2002 39 49
7. D.L. Gourlay, and H.A. Heit Pain and addiction: managing risk through comprehensive care J Addict Dis 27 2008 23 30
8. T.J. Ives, P.R. Chelminski, and C.A. Hammett-Stabler Predictors of opioid misuse in patients with chronic pain: a prospective cohort study BMC Health Serv Res 6 2006 46
9. A.M. Gilson, K.M. Ryan, D.E. Joranson, and J.L. Dahl A reassessment of trends in the medical use and abuse of opioid analgesics and implications for diversion control: 1997-2002 J Pain Symptom Manage 28 2004 176 188
10. L.R. Webster, and R.M. Webster Predicting aberrant behaviors in opioid-treated patients: preliminary validation of the Opioid Risk Tool Pain Med 6 2005 432 442
11. R. Chou, G.J. Fanciullo, and P.G. Fine Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain J Pain 10 2009 113 130
12. R.K. Portenoy, J.T. Farrar, and M.M. Backonja Long-term use of controlled-release oxycodone for noncancer pain: results of a 3-year registry study Clin J Pain 23 2007 287 299
13. T.J. Cicero, G. Wong, and Y. Tian Co-morbidity and utilization of medical services by pain patients receiving opioid medications: data from an insurance claims database Pain 144 2009 20 27
14. D.M. Simpson, J. Messina, F. Xie, and M. Hale Fentanyl buccal tablet for the relief of breakthrough pain in opioid-tolerant adult patients with chronic neuropathic pain: a multicenter, randomized, double-blind, placebo-controlled study Clin Ther 29 2007 588 601 (Pubitemid 47016640)
15. R.K. Portenoy, J. Messina, F. Xie, and J. Peppin Fentanyl buccal tablet (FBT) for relief of breakthrough pain in opioid-treated patients with chronic low back pain: a randomized, placebo-controlled study Curr Med Res Opin 23 2007 223 233 (Pubitemid 46191684)
16. J.T. Farrar, E. Michna, J. Messina, and F. Xie Fentanyl buccal tablet (FBT) in opioid-tolerant patients with non-cancer-related breakthrough pain (BTP) on around-the-clock opioids: a 12-week study using a novel double-blind, placebo-controlled design [abstract 130] Pain Med 9 2008 102
17. Fine PG, Messina J, Xie F, Rathmell J. Long-term safety and tolerability of fentanyl buccal tablet for the treatment of breakthrough pain in opioid-tolerant patients with chronic pain: an 18-month study. J Pain Symptom Manage XX-XX [In press].
18. R.K. Portenoy Opioid therapy for chronic nonmalignant pain: a review of the critical issues J Pain Symptom Manage 11 1996 203 217
19. S.A. Dunbar, and N.P. Katz Chronic opioid therapy for nonmalignant pain in patients with a history of substance abuse: report of 20 cases J Pain Symptom Manage 11 1996 163 171
20. S.M. Wu, P. Compton, and R. Bolus The addiction behaviors checklist: validation of a new clinician-based measure of inappropriate opioid use in chronic pain J Pain Symptom Manage 32 2006 342 351
21. S.F. Butler, S.H. Budman, and K.C. Fernandez Development and validation of the current opioid misuse measure Pain 130 2007 144 156