Challenges and current methods for attenuation correction in PET/MR

Magnetic Resonance Materials in Physics, Biology and Medicine

Volumn 26, Issue 1, 2013, Pages 81-98

  Keereman, Vincent ^a   Mollet, Pieter ^a   Berker, Yannick ^b,c   Schulz, Volkmar ^b,c   Vandenberghe, Stefaan ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c PHILIPS RESEARCH LABORATORIES   (Netherlands)

Author keywords

Attenuation correction; Emission; PET MR; Template; Transmission; UTE

Indexed keywords

DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ALGORITHM; COMPUTER ASSISTED DIAGNOSIS; EQUIPMENT; HUMAN; IMAGE ENHANCEMENT; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; REVIEW;

ALGORITHMS; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS;

EID: 84874108578     PISSN: 09685243     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10334-012-0334-7     Document Type: Review

References (65)

1. Grazioso R, Ladebeck R, Schmand M (2005) APD-based PET for combined MR-PET imaging. In: Proceedings of the 13th scientific meeting, international society for magnetic resonance in medicine, Miami Beach, p 408
2. Pichler BJ, Judenhofer MS, Catana C (2006) Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI. J Nucl Med 47:639-647
3. Judenhofer MS, Catana C, Swann BK, Siegel SB, Jung WI, Nutt RE, Cherry SR, Claussen CD, Pichler BJ (2007) PET/MR images acquired with a compact MR- compatible PET detector in a 7-T magnet. Radiology 244:807-814
4. Schulz V, Solf T, Weissler B, Gebhardt P, Fischer P, Ritzert M, Mlotok V, Piemonte C, Zorzi N, Melchiorri M, Vandenberghe S, Keereman V, Schaeffter T, Marsden P (2009) A preclinical PET/MR insert for a human 3T MR scanner. IEEE Nucl Sci Conf R 2577-2579
5. Solf T, Schulz V, Weissler B, Thon A, Fischer P, Ritzert M, Mlotok V, Piemonte C, Zorzi N (2009) Solid-state detector stack for ToF-PET/MR. IEEE Nucl Sci Conf R 2798-2799
6. Lalush D, Wernick M (2004) Iterative image reconstruction. In: Wernick M, Aarsvold J (eds) Emission tomography: the fundamentals of PET and SPECT. Elsevier Academic Press, San Diego
7. Zaidi H (2007) Is MR-guided attenuation correction a viable option for dual-modality PET/MR Imaging? Radiology 244:639-642
8. Hubbel J (1969) Photon cross sections, attenuation coefficients, and energy absorption coefficients from 10 keV to 100 GeV. NSRDS-NBS 29. National Bureau of Standards, Washington, DC
9. International Commission on Radiation Units and Measurements (ICRU) (1989) Tissue substitutes in radiation, dosimetry and measurement. ICRU Report 44. ICRU, Bethesda, MD
10. Bailey D, Townsend D, Valk P, Maisey M (eds) (2005) Positron emission tomography: basic sciences. Springer, London
11. Keereman V, Van Holen R, Mollet P, Vandenberghe S (2011) The effect of errors in segmented attenuation maps on PET quantification. Med Phys 38:6010-6019
12. Dahlbom M, Hoffman E (1987) Problems in signal-to-noise ratio for attenuation correction in high resolution PET. IEEE T Nucl Sci 34:288-293
13. deKemp RA, Nahmias C (1994) Attenuation correction in PET using single photon transmission measurement. Med Phys 21:771-778
14. Beyer T, Townsend D, Brun T (2000) A combined PET/CT scanner for clinical oncology. J Nucl Med 41:1369-1379
15. Kinahan P, Townsend D, Beyer T, Sashin D (1998) Attenuation correction for a combined 3D PET/CT scanner. Med Phys 25:2046-2053
16. Burger C, Goerres G, Schoenes S, Buck A (2002) PET attenuation coefficients from CT images: experimental evaluation of the transformation of CT into PET 511-keV attenuation coefficients. Eur J Nucl Med 29:922-927
17. Beyer T, Antoch G, Blodgett T, Freudenberg LF, Akhurst T, Mueller S (2003) Dual- modality PET/CT imaging: the effect of respiratory motion on combined image quality in clinical oncology. Eur J Nucl Med Mol Imaging 30:588-596
18. Goerres G, Burger C, Kamel E, Seifert B, Kaim A, Buck A, Buehler T, Schulthess G (2003) Respiration-induced attenuation artifact at PET/CT: technical considerations. Radiology 226:906-910
19. Delso G, Ziegler S (2009) PET/MRI system design. Eur J Nucl Med Mol Imaging 36(Suppl 1):S86-S92
20. Delso G, Martinez-Moller A, Bundschuh R, Ladebeck R, Candidus Y, Faul D, Ziegler S (2010) Evaluation of the attenuation properties of MR equipment for its use in a whole-body PET/MR scanner. Phys Med Biol 55:4361-4374
21. Mawlawi O, Erasmus JJ, Pan T, Cody DD, Campbell R, Lonn AH, Kohlmyer S, Macapinlac HA, Podoloff DA (2006) Truncation artifact on PET/CT: impact on measurements of activity concentration and assessment of a correction algorithm. Am J Roentgenol 186:1458-1467
22. Beyer T, Bockisch A, Kühl H, Martinez MJ (2006) Whole-body 18F-FDG PET/CT in the presence of truncation artifacts. J Nucl Med 47:91-99
23. Berker Y, Franke J, Salomon A, Palmowski M, Donker H, Temur Y, Mottaghy F, Kuhl C, Izquierdo-Garcia D, Fayad Z, Kiessling F, Schulz V (2012) MRI-based attenuation correction for hybrid PET/MRI systems: a four-class tissue segmentation technique using a combined ultra-short echo time (UTE)/Dixon MR sequence. J Nucl Med 53:796-804
24. Montandon M, Zaidi H (2005) Atlas-guided non-uniform attenuation correction in cerebral 3D PET imaging. Neuroimage 25:278-286
25. Rota Kops E, Herzog H (2007) Alternative methods for attenuation correction for PET images in MR-PET scanners. IEEE Nucl Sci Conf R 4327-4330
26. Rota Kops E, Herzog H (2008) Template based attenuation correction for PET in MR-PET scanners. IEEE Nucl Sci Conf R 3786-3789
27. Hofmann M, Steinke F, Scheel V (2008) MRI-based attenuation correction for PET/MRI: a novel approach combining pattern recognition and atlas registration. J Nucl Med 49:1875-1883
28. Hofmann M, Bezrukov I, Mantlik F, Aschoff P, Steinke F, Beyer T, Pichler BJ, Scholkopf B (2011) MRI-based attenuation correction for whole-body PET/MRI: quantitative evaluation of segmentation- and atlas-based methods. J Nucl Med 52:1392-1399
29. Beyer T, Weigert M, Quick HH, Pietrzyk U, Vogt F, Palm C, Antoch G, Mueller S, Bockisch A (2008) MR-based attenuation correction for torso-PET/MR imaging: pitfalls in mapping MR to CT data. Eur J Nucl Med Mol Imaging 35:1142-1146
30. El Fakhri G, Kijewski MF, Johnson KA, Syrkin G, Killiany RJ, Becker JA, Zimmerman RE, Albert MS (2003) MRI-guided SPECT perfusion measures and volumetric MRI in prodromal Alzheimer disease. Arch Neurol 60:1066-1072
31. El Fakhri G, Kijewski MF, Moore SC (2001) Absolute activity quantitation from projections using an analytical approach: comparison with iterative methods in Tc-99 m and I-123 brain SPECT. IEEE T Nucl Sci 48:768-773
32. Zaidi H, Montandon M, Slosman D (2003) Magnetic resonance imaging-guided attenuation and scatter corrections in three-dimensional brain positron emission tomography. Med Phys 30:937-948
33. Zaidi H, Montandon M, Slosman D (2004) Attenuation compensation in cerebral 3D PET: effect of the attenuation map on absolute and relative quantitation. Eur J Nucl Med Mol Imaging 31:52-63
34. Schlemmer H, Pichler B, Schmand M, Burbar Z, Michel C, Ladebeck R, Jattke K, Townsend D, Nahmias C, Jacob P, Heiss W, Claussen C (2008) Simultaneous MR/PET imaging of the human brain: feasibility study. Radiology 248:1028-1035
35. Hu Z, Renisch S, Schweizer B, Blaffert T, Ojha N, Guo T, Tang J, Tung C, Kaste J, Schulz V, Torres I, Shao L (2010) MR-based attenuation correction for whole-body PET/MR system. IEEE Nucl Sci Conf R 2119-2122
36. Hu Z, Ojha N, Renisch S, Schulz V, Torres I, Buhl A, Pal D, Muswick G, Penatzer J, Guo T, Bönert P, Tung C, Kaste J, Morich M, Havens T, Maniawski P, Schafer W, GuÂ̈nther R, Krombach G, Shao L (2009) MR-based attenuation correction for a whole-body sequential PET/MR system. IEEE Nucl Sci Conf R 3508-3512
37. Rota Kops E, Wagenknecht G, Scheins J, Tellmann L, Herzog H (2009) Attenuation correction in MR-PET scanners with segmented T1-weighted MR images. IEEE Nucl Sci Conf R 2530-2533
38. Steinberg J, Jia G, Sammet S, Zhang J, Hall N, Knopp M (2010) Three-region MRI-based whole-body attenuation correction for automated PET reconstruction. Nucl Med Biol 37:227-235
39. Schulz V, Torres-Espallardo I, Renisch S, Hu Z, Ojha N, Börnert P, Perkuhn M, Niendorf T, Schafer WM, Brockmann H, Krohn T, Buhl A, Günther RW, Mottaghy FM, Krombach GA (2010) Automatic, three-segment, MR-based attenuation correction for whole-body PET/MR data. Eur J Nucl Med Mol Imaging 38:138-152
40. Dixon W (1984) Simple proton spectroscopic imaging. Radiology 153:189-194
41. Martinez-Moller A, Souvatzoglou M, Delso G, Bundschuh R, Chefd'hotel C, Ziegler S, Navab N, Schwaiger M, Nekolla S (2009) Tissue classification as a potential approach for attenuation correction in whole-body PET/MRI: evaluation with PET/CT data. J Nucl Med 50:520-526
42. Coombs B, Szumowski J, Coshow W (1997) Two-point Dixon technique for water-fat signal decomposition with B0 inhomogeneity correction. Magn Reson Med 38:884-889
43. Eiber M, Martinez-Möller A, Souvatzoglou M, Holzapfel K, Pickhard A, Loffelbein D, Santi I, Rummeny E, Ziegler S, Schwaiger M, Nekolla S, Beer A (2011) Value of a Dixon-based MR/PET attenuation correction sequence for the localization and evaluation of PET-positive lesions. Eur J Nucl Med Mol Imaging 38:1691-1701
44. Eiber M, Souvatzoglou M, Pickhard A, Loeffelbein D, Knopf A, Holzapfel K, Martinez-Moller A, Nekolla S, Scherer E, Schwaiger M, Rummeny E, Beer A (2011) Simulation of a MR-PET protocol for staging of head-and-neck cancer including Dixon MR for attenuation correction. Eur J Radiol. doi: 10.1016/j.ejrad.2011.10. 005
45. Gatehouse P, Bydder G (2003) Magnetic resonance imaging of short T2 components in tissue. Clin Radiol 58:1-19
46. Robson M, Gatehouse P, So P, Bell J (2004) Contrast enhancement of short T2 tissues using ultrashort TE (UTE) pulse sequences. Clin Radiol 59:720-726
47. Keereman V, Fierens Y, Broux T, De Deene Y, Lonneux M, Vandenberghe S (2010) MRI-based attenuation correction for PET/MRI using ultrashort echo time sequences. J Nucl Med 51:812-818
48. Catana C, Kouwe A, Benner T, Michel C, Hamm M, Fenchel M, Fischl B, Rosen B, Schmand M, Sorensen A (2010) Toward implementing an MRI-based PET attenuation-correction method for neurologic studies on the MR-PET brain proto-type. J Nucl Med 51:1431-1438
49. Johansson A, Karlsson M, Nyholm T (2011) CT substitute derived from MRI sequences with ultrashort echo time. Med Phys 38:2708-2717
50. Mollet P, Keereman V, Clementel E, Vandenberghe S (2012) Simultaneous MR-compatible emission and transmission imaging for PET using time-of-flight information. IEEE Trans Med Imaging. doi: 10.1109/TMI.2012.2198831
51. Jan S, Santin G, Strul D, Staelens S, Assie K, Autret D, Avner S, Barbier R, Bardies M, Bloomfield P, Brasse D, Breton V, Bruyndonckx P, Buvat I, Chatziioannou A, Choi Y, Chung Y, Comtat C, Donnarieix D, Ferrer L, Glick S, Groiselle C, Guez D, Honore P, Kerhoas-Cavata S, Kirov A, Kohli V, Koole M, Krieguer M, van der Laan D, Lamare F, Largeron G, Lartizien C, Lazaro D, Maas M, Maigne L, Mayet F, Melot F, Merheb C, Penacchio E, Perez J, Pietrzyk U, Rannou F, Rey M, Schaart D, Schmidtlein C, Simon L, Song T, Vieira J, Visvikis D, Van de Walle R, Wieers E, Morel C (2004) GATE: a simulation toolkit for PET and SPECT. Phys Med Biol 49:4543-4561
52. Segars P (2001) Development of a new dynamic NURBS-based cardiac-torso (NCAT) phantom. PhD thesis. University of North Carolina at Chapel Hill
53. Tai Y, Lin K, Dahlbom M, Hoffman E (1996) A hybrid attenuation correction technique to compensate for lung density in 3-D total body PET. IEEE T Nucl Sci 43:323-330
54. Xu M, Cutler P, Luk W (1996) Adaptive, segmented attenuation correction for whole-body PET imaging. IEEE T Nucl Sci 43:331-336
55. Censor Y, Gustafson DE, Lent A, Tuy H (1979) A new approach to the emission computerized tomography problem: simultaneous calculation of attenuation and activity coefficients. IEEE Trans Nucl Sci 26:2775-2779
56. Nuyts J, Dupont P, Stroobants S, Benninck R, Mortelmans L, Suetens P (1999) Simultaneous maximum a posteriori reconstruction of attenuation and activity distributions from emission sinograms. IEEE Trans Med Imaging 18:393-403
57. Dicken V (1999) A new approach towards simultaneous activity and attenuation reconstruction in emission tomography. Inverse Prob 15:931-960
58. Conti M (2011) Why is TOF PET reconstruction a more robust method in the presence of inconsistent data? Phys Med Biol 56:155-168
59. Defrise M, Rezzaei A, Nuyts J (2012) Time-of-flight PET data determine the attenuation sinogram up to a constant. Phys Med Biol 57:885-899
60. Welch A, Campbell C, Clackdoyle R, Natterer F, Hudson M, Bromiley A, Mikecz P, Chillcot F, Dodd M, Hopwood P, Craib S, Gullberg GT, Sharp P (1998) Attenuation correction in PET using consistency information. IEEE T Nucl Sci 45:3134-3141
61. Bromiley A, Welch A, Chilcott F, Waikar S, McCallum S, Dodd M, Craib S, Schweiger L, Sharp P (2001) Attenuation correction in PET using consistency conditions and a three-dimensional template. IEEE T Nucl Sci 48:1371-1377
62. Salomon A, Goedicke A, Schweizer B, Aach T, Schulz V (2011) Simultaneous reconstruction of activity and attenuation for PET/MR. IEEE Trans Med Imaging 30:804-813
63. Delso G, Martinez-Möller A, Bundschuh R, Nekolla S, Ziegler S (2010) The effect of limited MR field of view in MR/PET attenuation correction. Med Phys 37:2804-2812
64. Marshall H, Prato F, Deans L, Théberge J, Thompson R, Stodilka R (2012) Variable lung density consideration in attenuation correction of whole-body PET/MRI. J Nucl Med 53:977-984
65. Buerger C, Aitken A, Tsoumpas C, King A, Schulz V, Marsden P, Schaeffter T (2011) Investigation of 4D PET attenuation correction using Ultra-short Echo Time MR. IEEE Nucl Sci Conf R 3558-3561